公开(公告)号：US20050268535A1

公开(公告)日：2005-12-08

申请号：US10709868

申请日：2004-06-02

Applicant: Otis Nelson ,  Mark Nelson ,  A. Nelson ,  Chandra Prakash ,  Gilbert Chapelet

Inventor： Otis Nelson ,  Mark Nelson ,  A. Nelson ,  Chandra Prakash ,  Gilbert Chapelet

IPC: C10L1/18

CPC classification number: C10L10/02 ,  C10L1/143 ,  C10L1/1805 ,  C10L1/1852 ,  C10L1/19 ,  C10L1/1985 ,  C10L1/221 ,  C10L1/2383 ,  C10L1/2387 ,  C10L10/12

Abstract: Disclosed is a biodiesel fuel additive composition which accelerates combustion phenomenon, reduces ignition delay, and improves Cetane number, thereby lowering particulate emissions, and improving fuel economy in diesel engines.

Abstract translation: 公开了一种生物柴油燃料添加剂组合物，其加速燃烧现象，减少点火延迟，并提高十六烷值，从而降低颗粒物排放，并提高柴油发动机的燃油经济性。

公开(公告)号：US20050268533A1

公开(公告)日：2005-12-08

申请号：US10709863

申请日：2004-06-02

Applicant: Otis Nelson ,  Mark Nelson ,  A. Nelson ,  Chandra Prakash ,  Gilbert Chapelet

Inventor： Otis Nelson ,  Mark Nelson ,  A. Nelson ,  Chandra Prakash ,  Gilbert Chapelet

IPC: C10L1/18

CPC classification number: C10L1/14 ,  C10L1/143 ,  C10L1/1805 ,  C10L1/1852 ,  C10L1/1985 ,  C10L1/221 ,  C10L1/2383 ,  C10L1/2387 ,  C10L10/04

Abstract: Disclosed is an ether containing motor fuel additive composition which synergistically interacts with the ether additive to reduce fuel intake system deposit formation and/or combustion chamber deposit formation, thereby reducing engine ORI and maintaining desired engine performance.

Abstract translation: 公开了一种含醚的运动燃料添加剂组合物，其与醚添加剂协同相互作用以减少燃料进入系统沉积物形成和/或燃烧室沉积物形成，从而减少发动机ORI并保持期望的发动机性能。

公开(公告)号：US20050268532A1

公开(公告)日：2005-12-08

申请号：US10709862

申请日：2004-06-02

Applicant: Otis Nelson ,  Mark Nelson ,  A. Nelson ,  Chandra Prakash ,  Gilbert Chapelet

Inventor： Otis Nelson ,  Mark Nelson ,  A. Nelson ,  Chandra Prakash ,  Gilbert Chapelet

IPC: C10L1/18

CPC classification number: C10L10/10 ,  C10L1/143 ,  C10L1/1805 ,  C10L1/1824 ,  C10L1/1852 ,  C10L1/1985 ,  C10L1/221 ,  C10L1/2383 ,  C10L1/2387 ,  C10L1/305 ,  C10L10/04

Abstract: Disclosed is a MMT containing motor fuel additive composition which synergistically combines the octane enhancing capabilities of MMT with the benefits of a special additive package to reduce both fuel intake system deposit formation and combustion chamber deposit formation, thereby reducing engine ORI and maintaining desired engine performance.

Abstract translation: 公开了一种含有MMT的运动燃料添加剂组合物，其协同地将MMT的辛烷值增强能力与特殊添加剂包装的优点相结合，以减少燃料进料系统沉积物形成和燃烧室沉积物形成，从而减少发动机ORI并保持期望的发动机性能。

公开(公告)号：US20050256177A1

公开(公告)日：2005-11-17

申请号：US11131020

申请日：2005-05-16

Applicant: Matthew Marx ,  Chandra Prakash ,  Zhuang Miao

Inventor： Matthew Marx ,  Chandra Prakash ,  Zhuang Miao

IPC: A61K31/425 ,  C07D275/02 ,  C07D275/03 ,  C07D417/02

CPC classification number: C07D275/03

Abstract: The invention relates to compounds of the formula 1 wherein X1, X2 and X3 independently is a halogen; p is an integer from 1 to 3; and R is —COOH, OR1 wherein R1 is a substituted isothiazole ring, or SR2 wherein R2 is (CH2)qC(COOH)(NHC(O)R3) wherein q is an integer from 0 to 3, and R3 is (C1-C4)alkyl; and to pharmaceutically acceptable salts, prodrugs and solvates thereof. The invention also relates to methods of treating a hyperproliferative disorder in a mammal by administering the compounds of formula 1 and to pharmaceutical compositions containing the compounds of formula 1.

Abstract translation: 本发明涉及式1的化合物，其中X 1，X 2和X 3独立地是卤素; p是1至3的整数; 并且R是-COOH，其中R 1是取代的异噻唑环或其中R 2 O 2的SR 2 是（CH 2）2 C（COOH）（NHC（O）R 3）其中q是0-3的整数， 和R 3是（C 1 -C 4 - ）烷基; 以及其药学上可接受的盐，前药和溶剂化物。 本发明还涉及通过施用式1化合物和含有式1化合物的药物组合物来治疗哺乳动物中过度增殖性疾病的方法。