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公开(公告)号：US20100074901A1
公开(公告)日：2010-03-25
申请号：US12251518
申请日：2008-10-15
Applicant: Marc Hubert Mercken , Jacqueline M. Benson , Sun-Yung S. Jung , Haiyan Jiang , Gopalan Raghunathan , Lionella Borozdina-Birch
Inventor： Marc Hubert Mercken , Jacqueline M. Benson , Sun-Yung S. Jung , Haiyan Jiang , Gopalan Raghunathan , Lionella Borozdina-Birch
IPC: A61K39/395 , G01N33/567 , C12P21/06 , C12N5/00 , C12N5/02 , C12N1/00 , C07K16/18 , C07H21/04 , C12P21/00
CPC classification number: C07K16/18 , A61K2039/505 , C07K2317/21 , C07K2317/56 , C07K2317/565
Abstract: The present invention relates to at least one novel human anti-amyloid antibody, including isolated nucleic acids that encode at least one anti-amyloid antibody, amyloid, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
Abstract translation: 本发明涉及至少一种新的人抗淀粉样蛋白抗体，包括编码至少一种抗淀粉样蛋白抗体，淀粉样蛋白，载体，宿主细胞，转基因动物或植物的分离的核酸及其制备和使用方法，包括 治疗组合物，方法和装置。
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公开(公告)号：USD586725S1
公开(公告)日：2009-02-17
申请号：US29324355
申请日：2008-09-11
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公开(公告)号：USD533132S1
公开(公告)日：2006-12-05
申请号：US29243856
申请日：2005-12-01
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公开(公告)号：USD533131S1
公开(公告)日：2006-12-05
申请号：US29243855
申请日：2005-12-01
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公开(公告)号：US5793895A
公开(公告)日：1998-08-11
申请号：US697652
申请日：1996-08-28
Applicant: Yuan-Chi Chang , Zon-Yin Shae , Marc Hubert Willebeek-LeMair
Inventor： Yuan-Chi Chang , Zon-Yin Shae , Marc Hubert Willebeek-LeMair
CPC classification number: H04N19/89 , H04N19/45 , H04N19/60 , H04N19/61 , H04N19/107
Abstract: A method and apparatus for compressing video data to improve its tolerance to error, especially with a low bit rate network. With this invention video data is divided into a number of frames and each frame is divided into a number of macroblocks. A dependency count is assigned to each macroblock, and if the dependency count for the macroblock exceeds or is equal to a threshold, the dependency block is intra-coded using low bit rate coding algorithm. If the dependency count is below the threshold, the macroblock is inter-coded.
Abstract translation: 一种用于压缩视频数据以提高其对错误的容忍度的方法和装置，特别是对于低比特率网络。 利用本发明，视频数据被分成多个帧，并且每个帧被分成多个宏块。 对每个宏块分配依赖关系计数，如果宏块的相关性计数超过或等于阈值，则使用低比特率编码算法对依赖关系块进行帧内编码。 如果依赖关系计数低于阈值，则宏块被编码。
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Patent Agency Ranking
26.发明授权N-11 truncated amyloid-beta Aβ11-x monoclonal antibodies and compositions 有权N-11截短的淀粉样蛋白-βA和b-11单克隆抗体和组合物公开(公告)号：US09329189B2
公开(公告)日：2016-05-03
申请号：US10528928
申请日：2003-09-09
Applicant: Marc Hubert Mercken , Marc Maria Pierre Vandermeeren
Inventor： Marc Hubert Mercken , Marc Maria Pierre Vandermeeren
CPC classification number: G01N33/6896 , C07K16/18 , C07K2317/34 , G01N2333/4709 , G01N2800/2821 , G01N2800/52
Abstract: This invention relates to antibodies, including specified portions or variants, specific for at least the human Amyloid-beta 11 N-terminal site, i.e. Aβ11-x peptides. It further provides methods of making and using said antibodies, including therapeutic formulations, administration and devices.
Abstract translation: 本发明涉及针对至少人淀粉样蛋白-β11N-末端位点即A和B-11肽的特异性的抗体，包括特定的部分或变体。 其进一步提供制备和使用所述抗体的方法，包括治疗剂型，给药方式和装置。
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公开(公告)号：US08919494B2
公开(公告)日：2014-12-30
申请号：US13585533
申请日：2012-08-14
Applicant: Brian Bobby Burkett , Galdemir Cezar Botura , Claude Marc Hubert , David Bert Sweet , Joseph Christopher Zecca , Timothy Robert Olson
Inventor： Brian Bobby Burkett , Galdemir Cezar Botura , Claude Marc Hubert , David Bert Sweet , Joseph Christopher Zecca , Timothy Robert Olson
IPC: E04B1/86
CPC classification number: H01C17/02 , B64D15/12 , B64D33/02 , B64D2033/0206 , B64D2033/0233 , Y10T29/49083
Abstract: An electric heater (40) for integration into an acoustic panel (20) having sound-penetrating pores (30) communicating with a sound-canceling medium. The heater (40) includes an electrically conductive layer (53) with resistance-setting apertures (63) filled with sealant (73). Openings (83), which contribute to the sound-penetrating pores (30), extend through the sealant-filled apertures (63). The acoustic panel (20) can be assimilated into an aircraft component, such as a nacelle inlet lip, which requires both noise-reducing and ice-protecting features.
Abstract translation: 一种用于集成到具有与声音消除介质通信的声音穿透孔（30）的声学面板（20）的电加热器（40）。 加热器（40）包括具有填充有密封剂（73）的电阻设定孔（63）的导电层（53）。 有助于声音穿透孔（30）的开口（83）延伸穿过密封剂填充的孔（63）。 声学面板（20）可以被吸收到飞机部件中，例如机舱入口唇缘，其需要降噪和防冰特征。
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公开(公告)号：US08461145B2
公开(公告)日：2013-06-11
申请号：US12746092
申请日：2008-12-04
Applicant: Henricus Jacobus Maria Gijsen , Marc Hubert Mercken
Inventor： Henricus Jacobus Maria Gijsen , Marc Hubert Mercken
IPC: A61K31/55 , A61K31/553 , C07D233/20 , C07D267/20 , A61P25/00
CPC classification number: C07D267/20 , C07D223/20
Abstract: The present invention is related to novel tricyclic compounds of formula (I) having TRPA1 receptor agonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use as pharmacological tools, or as irritant incapacitants, or in the treatment of diseases linked to the modulation of the TRPA1 receptors in animals, in particular humans.
Abstract translation: 本发明涉及具有TRPA1受体激动性的式（I）的新型三环化合物，包含这些化合物的药物组合物，用于制备这些化合物的化学方法及其作为药理学工具的用途，或作为刺激性丧失能力的治疗或治疗疾病 与动物，特别是人类中TRPA1受体的调节有关。
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公开(公告)号：US20110308723A1
公开(公告)日：2011-12-22
申请号：US13217709
申请日：2011-08-25
Applicant: CLAUDE MARC HUBERT , MICHAEL JOHN LAYLAND , LEE A. TICHENOR , MICHAEL RAY ATEN , RON LONG
Inventor： CLAUDE MARC HUBERT , MICHAEL JOHN LAYLAND , LEE A. TICHENOR , MICHAEL RAY ATEN , RON LONG
CPC classification number: B29C70/446 , B29C33/48 , B29C70/54 , B29L2031/3076 , Y10S425/06 , Y10T29/49895 , Y10T29/49904
Abstract: A multi-segment tool and tooling system for vacuum forming a composite part. A tool can include a first tool having first and second surfaces. A second tool can have an opening positioned on a first tool in a location other than the first surface or the second surface. The first tool and second tool can receive at least a portion of a preform composite. The first tool can have a vacuum barrier attached to the first surface and to the second surface encapsulating the preform composite and the second tool. A tooling system can include a first tool having a core and a base with a core extending upwards from the base. A second tool can be positioned upon the core where the core extends above the second tool. A vacuum barrier sealed to the base and the core can include a composite, the first tool and the second tool.
Abstract translation: 用于真空成型复合部件的多段工具和加工系统。 工具可以包括具有第一和第二表面的第一工具。 第二工具可以具有位于除了第一表面或第二表面之外的位置处的第一工具上的开口。 第一工具和第二工具可以容纳预制件复合材料的至少一部分。 第一工具可以具有附接到第一表面的真空阻挡层和封装预型件复合材料和第二工具的第二表面。 工具系统可以包括具有芯的第一工具和具有从基部向上延伸的芯的基部。 第二工具可以定位在芯部上，其中芯部在第二工具上方延伸。 密封到基部和芯部的真空屏障可以包括复合材料，第一工具和第二工具。
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公开(公告)号：US08025499B2
公开(公告)日：2011-09-27
申请号：US12263915
申请日：2008-11-03
Applicant: Claude Marc Hubert , Michael John Layland , Lee A. Tichenor , Michael Ray Aten , Ron Long
Inventor： Claude Marc Hubert , Michael John Layland , Lee A. Tichenor , Michael Ray Aten , Ron Long
CPC classification number: B29C70/446 , B29C33/48 , B29C70/54 , B29L2031/3076 , Y10S425/06 , Y10T29/49895 , Y10T29/49904
Abstract: A multi-segment tool and tooling system for vacuum forming a composite part. A tool can include a first tool having first and second surfaces. A second tool can have an opening positioned on a first tool in a location other than the first surface or the second surface. The first tool and second tool can receive at least a portion of a preform composite. The first tool can have a vacuum barrier attached to the first surface and to the second surface encapsulating the preform composite and the second tool. A tooling system can include a first tool having a core and a base with a core extending upwards from the base. A second tool can be positioned upon the core where the core extends above the second tool. A vacuum barrier sealed to the base and the core can include a composite, the first tool and the second tool.
Abstract translation: 用于真空成型复合部件的多段工具和加工系统。 工具可以包括具有第一和第二表面的第一工具。 第二工具可以具有位于除了第一表面或第二表面之外的位置处的第一工具上的开口。 第一工具和第二工具可以容纳预制件复合材料的至少一部分。 第一工具可以具有附接到第一表面的真空阻挡层和封装预型件复合材料和第二工具的第二表面。 工具系统可以包括具有芯的第一工具和具有从基部向上延伸的芯的基部。 第二工具可以定位在芯部上，其中芯部在第二工具上方延伸。 密封到基部和芯部的真空屏障可以包括复合材料，第一工具和第二工具。
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