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    APPARATUS AND METHODS FOR ANALYZING BODY FLUID SAMPLES
    27.
    发明申请
    APPARATUS AND METHODS FOR ANALYZING BODY FLUID SAMPLES 审中-公开

    公开(公告)号：US20100030137A1

    公开(公告)日：2010-02-04

    申请号：US12511014

    申请日：2009-07-28

    Applicant: W. Dale Hall ,  David N. Callicoat ,  Jennifer H. Gable ,  James R. Braig ,  Kenneth G. Witte ,  Mark Wechsler ,  Peter Rule ,  Richard Keenan

    Inventor： W. Dale Hall ,  David N. Callicoat ,  Jennifer H. Gable ,  James R. Braig ,  Kenneth G. Witte ,  Mark Wechsler ,  Peter Rule ,  Richard Keenan

    IPC: A61M5/168

    CPC classification number: A61B5/14546 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150358 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61M5/14212 ,  A61M2230/20

    Abstract: An apparatus is provided for monitoring a predetermined parameter of a patient's body fluid while infusing an infusion fluid into the patient. The apparatus comprises an infusion line and a catheter configured for insertion into a blood vessel of the patient, and a reversible infusion pump connected between a source of an infusion fluid and the infusion line and catheter. The apparatus further comprises a body fluid sensor assembly mounted in fluid communication with the infusion line and which includes a first sensor and a sample cell. The first sensor provides a signal indicative of a predetermined parameter of any fluid present in the infusion line. The sample cell is substantially transmissive to light comprising a wavelength λ. The apparatus further comprises a controller that is configured to operate the infusion pump in a forward direction so as to pump the infusion fluid through the infusion line and catheter for infusion into the patient. The controller is configured to intermittently interrupt its operating of the infusion pump in the forward direction to operate the infusion pump in a rearward direction so as to draw a body fluid sample from the patient through the catheter and infusion line. The body fluid sample drawn from the patient is disposed such that a first portion of the body fluid sample is in sensing contact with the first sensor of the body fluid sensor assembly, and a second portion of the body fluid sample is disposed within the sample cell of the body fluid sensor assembly. The controller further is configured to monitor the signal provided by the first sensor of the body fluid sensor assembly and to detect a change in the signal indicative of the arrival of the body fluid sample at the first sensor. The controller, in response to detecting the arrival of the body fluid sample at the first sensor, is configured to cease its operating of the infusion pump in the rearward direction. The signal produced by the first sensor provides an indication of a predetermined parameter of the patient's body fluid when the body fluid sample is in sensing contact with the first sensor.

    INFUSION FLOW INTERRUPTION METHOD AND APPARATUS
    28.
    发明申请
    INFUSION FLOW INTERRUPTION METHOD AND APPARATUS 审中-公开
    输注流中断方法和装置

    公开(公告)号：US20080161723A1

    公开(公告)日：2008-07-03

    申请号：US11850972

    申请日：2007-09-06

    Applicant: Richard Keenan ,  Jeffrey Chiou ,  Peter Rule ,  James R. Braig

    Inventor： Richard Keenan ,  Jeffrey Chiou ,  Peter Rule ,  James R. Braig

    IPC: A61B5/00 ,  A61M5/142

    CPC classification number: A61B5/4839 ,  A61B5/14532 ,  A61B5/14557 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150267 ,  A61B5/150305 ,  A61B5/150755 ,  A61B5/150786 ,  A61B5/150824 ,  A61B5/150854 ,  A61B5/153 ,  A61B5/157 ,  A61M1/3609 ,  A61M5/14 ,  A61M5/1415 ,  A61M2005/1404 ,  A61M2005/1726 ,  A61M2230/201

    Abstract: Disclosed are systems, apparatus and methods for determining information related to analyte(s) (e.g., concentration) in a sample such as biological fluid. An analysis system for determining information relating to at least one analyte in a sample of biological fluid can be configured to: withdraw the sample of biological fluid from the source of biological fluid; interrupt the flow of infusion fluid while the sample of biological fluid is withdrawn; analyze the withdrawn biological fluid to determine information relating to at least one analyte; and resume the flow of infusion fluid after the sample of biological fluid is withdrawn. A method of interrupting flow of an infusion fluid without triggering an alarm can comprise, while the flow of the infusion fluid is interrupted, diverting the flow of the infusion fluid from a fluid passageway to an expandable volume at a rate that maintains constant flow from an infusion pump.

    Abstract translation: 公开了用于确定样品（例如生物流体）中与分析物（例如浓度）相关的信息的系统，装置和方法。 用于确定与生物流体样品中的至少一种分析物相关的信息的分析系统可以被配置为：从生物流体源中抽出生物流体的样品; 中断生物流体样本取出时输液的流动; 分析所抽取的生物流体以确定与至少一种分析物有关的信息; 并在取出生物流体的样品后恢复输注液的流动。 一种在不触发报警的情况下中断输注流体的流动的方法可以包括在输注流体的流动被中断的同时将输注流体的流动从流体通道转移到可膨胀体积，其速率保持恒定的流量 输液泵。

    Analyte detection system for multiple analytes
    30.
    发明申请
    Analyte detection system for multiple analytes 有权
    多种分析物的分析物检测系统

    公开(公告)号：US20060189858A1

    公开(公告)日：2006-08-24

    申请号：US11314176

    申请日：2005-12-21

    Applicant: Bernhard Sterling ,  James Braig ,  Kenneth Witte ,  Peter Rule ,  Richard Keenan ,  W. Hall

    Inventor： Bernhard Sterling ,  James Braig ,  Kenneth Witte ,  Peter Rule ,  Richard Keenan ,  W. Hall

    IPC: A61B5/00 ,  A61M31/00

    CPC classification number: A61M5/1723 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14557 ,  A61B5/1495 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61M5/14212 ,  A61M5/14232 ,  A61M5/16854 ,  A61M2205/12 ,  A61M2230/20 ,  A61M2230/201 ,  G01N1/14 ,  G01N21/05 ,  G01N21/274 ,  G01N21/35 ,  G01N2021/0346

    Abstract: An apparatus for analyzing the composition of bodily fluid. The apparatus comprises a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient; and a pump unit in operative engagement with the fluid handling network. The pump unit has an infusion mode in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus further comprises a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample. In one implementation, the pump unit comprises a first pump operable in the infusion mode but not in the sample draw mode, and a second pump operable in the sample draw mode but not in the infusion mode.

    Abstract translation: 一种用于分析体液组成的装置。 该装置包括流体处理网络，其包括被配置为保持患者体内与体液的流体连通的患者端; 以及与所述流体处理网络操作地接合的泵单元。 泵单元具有输注模式，其中泵单元可操作以通过患者端向患者输送输注流体，以及抽样模式，其中泵单元可操作以从患者抽取体液样本，通过 病人结束 所述设备还包括定位成分析样品的至少一部分的光谱分析仪; 与光谱分析仪通信或并入其中的处理器; 以及可由处理器执行的存储的程序指令，以获得样本的两个或多个属性的测量。 在一个实施方案中，泵单元包括可在输液模式中操作但不在样品抽取模式中的第一泵，以及可在样品抽取模式中操作但不在输注模式中的第二泵。

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