公开(公告)号：US06992226B2

公开(公告)日：2006-01-31

申请号：US10475215

申请日：2002-04-24

Applicant: Rolf-Hartmuth Fischer ,  Markus Rösch ,  Norbert Götz

Inventor： Rolf-Hartmuth Fischer ,  Markus Rösch ,  Norbert Götz

IPC: C07C41/18

CPC classification number: C07C41/18 ,  C07B31/00 ,  C07C43/2055

Abstract: A process for preparing toluene derivatives of the formula I where R1, R2 and R3 are, independently of one another, hydrogen, alkyl radicals, hydroxyl groups and/or alkoxy groups, comprises reacting the corresponding benzoic acids, benzoic esters or benzoic anhydrides with hydrogen in the presence of a catalyst.

Abstract translation: 制备式I的甲苯衍生物的方法，其中R 1，R 2和R 3 3彼此独立地为氢，烷基 基团，羟基和/或烷氧基包括在催化剂存在下使相应的苯甲酸，苯甲酸酯或苯甲酸酐与氢反应。

公开(公告)号：US06906228B2

公开(公告)日：2005-06-14

申请号：US10220566

申请日：2001-03-01

Applicant: Rolf Hartmuth Fischer ,  Rolf Pinkos ,  Stephan Andreas Schunk ,  Joachim Wulff-Döring ,  Frank Stein ,  Thomas Nöbel ,  Sylvia Huber

Inventor： Rolf Hartmuth Fischer ,  Rolf Pinkos ,  Stephan Andreas Schunk ,  Joachim Wulff-Döring ,  Frank Stein ,  Thomas Nöbel ,  Sylvia Huber

IPC: B01J21/18 ,  B01J23/656 ,  B01J23/89 ,  C07C29/17 ,  C07C29/136 ,  C07C29/14 ,  C07C29/141 ,  C07C29/143 ,  C07C29/145 ,  C07C29/147 ,  C07C29/149 ,  C07C29/146 ,  C07C29/148

CPC classification number: C07C29/177 ,  B01J21/18 ,  B01J23/6567 ,  B01J23/8986 ,  C07C2601/20 ,  C07C31/207 ,  C07C31/20 ,  C07C31/133

Abstract: In a process for preparing alcohols by catalytic hydrogenation of carbonyl compounds over a catalyst comprising rhenium on activated carbon, the catalyst used comprises rhenium (calculated as metal) in a weight ratio to the activated carbon of from 0.0001 to 0.5, platinum (calculated as metal) in a weight ratio to the activated carbon of from 0.0001 to 0.5 and, if appropriate, at least one further metal selected from among Zn, Cu, Ag, Au, Ni, Fe, Ru, Mn, Cr, Mo, W and V in a weight ratio to the activated carbon of from 0 to 0.25, and the activated carbon has been nonoxidatively pretreated It is also possible to prepare ethers and lactones if the hydrogen pressure is not more than 25 bar. In this case, the activated carbon in the catalyst may also have been nonoxidatively pretreated.

Abstract translation: 在通过羰基化合物催化氢化羰基化合物的方法中，所用的催化剂包括铼在活性炭上的催化剂，所用的催化剂包括铼（以金属计）与活性炭的重量比为0.0001至0.5，铂（以金属计算 ），活性炭的重量比为0.0001〜0.5，如果合适，选自Zn，Cu，Ag，Au，Ni，Fe，Ru，Mn，Cr，Mo，W和V中的至少一种以上的金属 活性炭的重量比为0至0.25，并且活性炭未经氧化预处理。如果氢气压力不超过25巴，也可制备醚和内酯。 在这种情况下，催化剂中的活性炭也可以被非氧化预处理。

公开(公告)号：US20050032627A1

公开(公告)日：2005-02-10

申请号：US10500718

申请日：2003-01-20

Applicant: Nils Bottke ,  Rolf-Hartmuth Fischer ,  Thomas Nobel ,  Markus Rosch

Inventor： Nils Bottke ,  Rolf-Hartmuth Fischer ,  Thomas Nobel ,  Markus Rosch

IPC: C07C41/18 ,  B01J23/00 ,  B01J23/72 ,  B01J23/755 ,  B01J23/885 ,  B01J23/889 ,  C07B61/00 ,  C07C43/205 ,  B01J29/04

CPC classification number: B01J23/8892 ,  B01J23/002 ,  B01J23/72 ,  B01J23/755 ,  B01J23/885 ,  B01J23/8898 ,  B01J2523/00 ,  C07C2523/72 ,  C07C2523/75 ,  C07C2523/755 ,  B01J2523/17 ,  B01J2523/31 ,  B01J2523/68 ,  B01J2523/847 ,  B01J2523/12 ,  B01J2523/51 ,  B01J2523/72 ,  B01J2523/845 ,  B01J2523/41 ,  B01J2523/48

Abstract: A process for preparing toluene derivatives of the formula I, where R1, R2 and R3 independently of one another are hydrogen, halogen, C1-C6-alkyl, hydroxyl or C1-C6-alkoxy, by hydrogenating benzaldehydes and/or benzyl alcohols of the formula II, with hydrogen in the presence of a catalyst, which is described in more detail in the description.

Abstract translation: 制备式I的甲苯衍生物的方法，其中R 1，R 2和R 3彼此独立地是氢，卤素，C 1 -C 6 - 烷基，羟基或C 1 -C 6 - 烷氧基，由 在催化剂存在下用氢气将式II的苯甲醛和/或苄醇氢化，这在描述中更详细地描述。

公开(公告)号：US06730800B2

公开(公告)日：2004-05-04

申请号：US10433425

申请日：2003-06-04

Applicant: Rolf-Hartmuth Fischer ,  Frank Stein ,  Rolf Pinkos ,  Michael Hesse ,  Michael Jolyon Sprague ,  Markus Rösch ,  Holger Borchert ,  Stephan Schlitter ,  Ralf-Thomas Rahn ,  Alexander Weck

Inventor： Rolf-Hartmuth Fischer ,  Frank Stein ,  Rolf Pinkos ,  Michael Hesse ,  Michael Jolyon Sprague ,  Markus Rösch ,  Holger Borchert ,  Stephan Schlitter ,  Ralf-Thomas Rahn ,  Alexander Weck

IPC: C07D33102

CPC classification number: B01J23/72 ,  B01J23/80 ,  C07D307/08

Abstract: Unsubstituted or alkyl-substituted THF is obtained by catalytic hydrogenation in the gas phase of C4-dicarboxylic acids and/or their derivatives using a catalyst comprising 20% by weight, preferably >30% by weight, in particular from 35 to 90% by weight, of an oxidic support having acid centers, at a hot spot temperature of from 240 to 310° C., preferably from 240 to 280° C., and a WHSV over the catalyst of from 0.01 to 1.0, preferably from 0.02 to 1, in particular from 0.05 to 0.5, kg of starting material/l of catalyst x hour.

Abstract translation: 未取代或烷基取代的THF通过使用包含<80重量％，优选<70重量％，特别是10至65重量％的催化剂在C4-二羧酸和/或其衍生物的气相中通过催化氢化获得， 重量的CuO和> 20重量％，优选> 30重量％，特别是35至90重量％的具有酸中心的氧化载体，在热点温度为240-310℃， 优选为240〜280℃，催化剂上的WHSV为0.01〜1.0，优选为0.02〜1，特别优选为0.05〜0.5kg的原料/ l催化剂x小时。

公开(公告)号：US06716937B2

公开(公告)日：2004-04-06

申请号：US10312851

申请日：2003-01-02

Applicant: Gerd Bohner ,  Thomas Domschke ,  Rolf-Hartmuth Fischer ,  Martin Haubner ,  Christoph Sigwart ,  Ulrich Steinbrenner ,  Christian Tragut

Inventor： Gerd Bohner ,  Thomas Domschke ,  Rolf-Hartmuth Fischer ,  Martin Haubner ,  Christoph Sigwart ,  Ulrich Steinbrenner ,  Christian Tragut

IPC: C08F244

CPC classification number: C08G65/30 ,  C08G65/20

Abstract: A process for the single-stage preparation of polytetrahydrofuran and/or tetrahydrofuran copolymers having a mean molecular weight of from 650 to 5000 dalton by polymerization of tetrahydrofuran over a heterogeneous acid catalyst in the presence of at least one telogen and/or comonomer selected from the group consisting of alpha,omega-diols, water, polytetrahydrofuran having a molecular weight of from 200 to 700 dalton and cyclic ethers comprises a) separating off the catalyst and/or downstream products of the catalyst suspended and/or dissolved in the output from the polymerization, b) fractionating the resulting catalyst-free output from the polymerization in at least one distillation step to give a distillation residue comprising the polymerization product and at least one tetrahydrofuran fraction and returning at least part of the tetrahydrofuran fraction to the polymerization and c) separating low molecular weight polytetrahydrofuran and/or tetrahydrofuran copolymers having a mean molecular weight of from 200 to 700 dalton from the distillation residue from work-up step b) and isolating polytetrahydrofuran and/or tetrahydrofuran copolymers having a mean molecular weight of from 650 to 5000 dalton.

Abstract translation: 一种通过在多相酸催化剂的存在下，在四氢呋喃和/或共聚单体的存在下，通过四氢呋喃聚合，单分级制备平均分子量为650-5000道尔顿的聚四氢呋喃和/或四氢呋喃共聚物的方法，该共聚单体选自 由α，ω-二醇，水，分子量为200至700道尔顿的聚四氢呋喃和环醚组成的组包括：a）将催化剂和/或催化剂的下游产物分离出悬浮和/或溶解在聚合物的输出中 b）在至少一个蒸馏步骤中将所得无催化剂的产物从聚合中分馏，得到包含聚合产物和至少一种四氢呋喃馏分的蒸馏残余物，并将至少部分四氢呋喃馏分返回到聚合反应中， 分子量的四氢呋喃和/或四氢呋喃共聚物 来自后处理步骤b）的蒸馏残余物的200至700道尔顿的颗粒重量，并分离平均分子量为650-5000道尔顿的聚四氢呋喃和/或四氢呋喃共聚物。

公开(公告)号：US06686465B2

公开(公告)日：2004-02-03

申请号：US10258943

申请日：2002-10-29

Applicant: Frank Ohlbach ,  Andreas Ansmann ,  Peter Bassler ,  Rolf-Hartmuth Fischer ,  Hermann Luyken ,  Stefan Maixner ,  Johann-Peter Melder

Inventor： Frank Ohlbach ,  Andreas Ansmann ,  Peter Bassler ,  Rolf-Hartmuth Fischer ,  Hermann Luyken ,  Stefan Maixner ,  Johann-Peter Melder

IPC: C07D20108

CPC classification number: C07D201/08

Abstract: A process is provided for the preparation of cyclic lactams of formula (II): in which n and m can each have the values 0, 1, 2, 3, 4, 5, 6, 7, 8 and 9 and the sum of n+m is at least 3, preferably at least 4, and R1 and R2 are C1-C6-alkyl, C5-C7-cycloalkyl or C6-C12-aryl groups, by reacting a compound (I) of the formula in which R1, R2, m and n are as defined above and R are [sic] nitrile, carboxamide and carboxylic acid groups, with steam in the gas phase.

Abstract translation: 提供了制备式（II）的环状内酰胺的方法：其中n和m各自可以具有0,1,2,3,4,5,6,7,8和9以及n + m为至少3，优选至少4，R 1和R 2为C 1 -C 6 - 烷基，C 5 -C 7 - 环烷基或C 6 -C 12 - 芳基，通过使 R 1，R 2，m和n如上所定义，R是具有气相中蒸汽的[sic]腈，甲酰胺和羧酸基团的甲醛。

公开(公告)号：US06683180B2

公开(公告)日：2004-01-27

申请号：US10297209

申请日：2002-12-04

Applicant: Frank Ohlbach ,  Andreas Ansmann ,  Rolf-Hartmuth Fischer ,  Johann-Peter Melder

Inventor： Frank Ohlbach ,  Andreas Ansmann ,  Rolf-Hartmuth Fischer ,  Johann-Peter Melder

IPC: C07D20108

CPC classification number: C07D201/08 ,  Y02P20/52

Abstract: A process is provided for the preparation of caprolactam from a compound of formula (I): NC—(CH2)5—CO—R  (I) in which R is a carboxamide, carboxylic acid or carboxylic acid ester group, wherein a) a compound (I) or a mixture of such compounds, in the presence of ammonia and optionally a liquid diluent (VI), is hydrogenated with hydrogen in the presence of a catalyst (II) to give a mixture (III), b) the hydrogen and the catalyst (II) are separated from the mixture (III) to give a mixture (IV), and c) the mixture (IV), optionally in the presence of a liquid diluent (VII), is converted to caprolactam in the presence of a catalyst (V).

Abstract translation: 提供了从式（I）化合物制备己内酰胺的方法：其中R是羧酰胺，羧酸或羧酸酯基，其中a）化合物（I）或这些化合物的混合物，在存在下 的氨和任选的液体稀释剂（VI）在催化剂（II）的存在下用氢氢化，得到混合物（III），b）将氢气和催化剂（II）从混合物（III）中分离出来， 任选在液体稀释剂（VII）的存在下，将混合物（IV）和（c）混合物（IV）在催化剂（V）的存在下转化成己内酰胺。

公开(公告)号：US5827938A

公开(公告)日：1998-10-27

申请号：US635684

申请日：1996-04-22

Applicant: Werner Schnurr ,  Guido Voit ,  Klemens Flick ,  Johann-Peter Melder ,  Rolf-Hartmuth Fischer ,  Wolfgang Harder

Inventor： Werner Schnurr ,  Guido Voit ,  Klemens Flick ,  Johann-Peter Melder ,  Rolf-Hartmuth Fischer ,  Wolfgang Harder

IPC: B01J25/02 ,  C07B61/00 ,  C07C209/48 ,  C07C211/12 ,  C07C253/30 ,  C07C255/24 ,  C07C255/00

CPC classification number: C07C209/48 ,  C07C253/30 ,  Y02P20/584

Abstract: A process for the coproduction of 6-aminocapronitrile (ACN) and hexamethylenediamine (HMD) by treatment of adiponitrile (ADN) with hydrogen in the presence of a nickel-containing catalyst at temperatures not below room temperature and elevated hydrogen partial pressure in the presence or absence of a solvent comprises, after the conversion based on ADN and/or the selectivity based on ACN has or have dropped below a defined value (a) interrupting the treatment of ADN with hydrogen by stopping the feed of ADN and of the solvent, if used, (b) treating the catalyst at from 150.degree. to 400.degree. C. with hydrogen using a hydrogen pressure within the range from 0.1 to 30 MPa and a treatment time within the range from 2 to 48 h, and (c) then continuing the hydrogenation of ADN with the treated catalyst of stage (b).

Abstract translation: 在含镍催化剂存在下，在不低于室温的温度和氢分压升高的情况下，通过用氢气处理己二腈（ADN），共同生产6-氨基己腈（ACN）和六亚甲基二胺（HMD）的方法， 没有溶剂包括在基于ADN的转化和/或基于ACN的选择性之后，或者已经降低到低于定义的值（a）通过停止ADN和溶剂的进料而中止用氢处理ADN，如果 使用，（b）使用氢气压力为0.1〜30MPa，处理时间为2〜48小时，用氢气在150〜400℃下处理催化剂，（c）然后继续 用（b）阶段处理的催化剂氢化ADN。

公开(公告)号：US20110015429A1

公开(公告)日：2011-01-20

申请号：US12867509

申请日：2009-01-29

Applicant: Rolf Pinkos ,  Tilman Sirch ,  Gerd-Dieter Tebben ,  Rolf-Hartmuth Fischer

Inventor： Rolf Pinkos ,  Tilman Sirch ,  Gerd-Dieter Tebben ,  Rolf-Hartmuth Fischer

IPC: C07C69/67

CPC classification number: C07C29/50 ,  C07C45/33 ,  C07C51/367 ,  C07C67/08 ,  C07C2601/14 ,  C07C49/403 ,  C07C59/01 ,  C07C69/675 ,  C07C35/08

Abstract: The present application relates to an improved process for preparing 6-hydroxycaproic esters from the by-product mixtures which are obtained in the oxidation of cyclohexane to cyclohexanol and cyclohexanone with oxygen or oxygen-comprising gas mixtures.

Abstract translation: 本申请涉及一种从副产物混合物中制备6-羟基己酸酯的改进方法，该方法是在用含氧或含氧气体混合物将环己烷氧化成环己醇和环己酮时获得的。

公开(公告)号：US07227029B2

公开(公告)日：2007-06-05

申请号：US10495358

申请日：2002-11-15

Applicant: Martin Rudloff ,  Peter Stops ,  Erhard Henkes ,  Helmut Schmidtke ,  Rolf-Hartmuth Fischer ,  Manfred Julius ,  Rolf Lebkücher ,  Karl-Heinz Ross

Inventor： Martin Rudloff ,  Peter Stops ,  Erhard Henkes ,  Helmut Schmidtke ,  Rolf-Hartmuth Fischer ,  Manfred Julius ,  Rolf Lebkücher ,  Karl-Heinz Ross

IPC: C07D207/12 ,  C07D307/20

CPC classification number: C07D207/267

Abstract: Process for the continuous preparation of N-methyl-2-pyrrolidone (NMP) by reacting gamma-butyrolactone (GBL) with monomethylamine (MMA) in the liquid phase, wherein GBL and MMA are used in a molar ratio of from 1:1.08 to 1:2 and the reaction is carried out at from 320 to 380° C. and an absolute pressure of from 70 to 120 bar.

Abstract translation: 通过使γ-丁内酯（GBL）与一甲胺（MMA）在液相中连续制备N-甲基-2-吡咯烷酮（NMP）的方法，其中GBL和MMA的摩尔比为1:1.08至 1：2，反应在320〜380℃，绝对压力为70〜120巴下进行。