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公开(公告)号:US20130186975A1
公开(公告)日:2013-07-25
申请号:US13720759
申请日:2012-12-19
Applicant: Stamford Devices Limited
Inventor: Brendan Hogan , Daniela Butan , Seamus Clifford , Michael Pomeroy , Mark Southern , David Shiel
IPC: B05B17/06
CPC classification number: B05B17/0646 , B05B15/18 , B05B17/06 , B05B17/0653 , B05B17/0669
Abstract: An aperture plate is formed from a palladium nickel alloy comprising about 89% palladium and about 11% nickel. There is a generally fine substantially equiaxed grain microstructure throughout the thickness of the aperture plate. The average grain width (W) is in the range of from 0.2 μm to 5.0 μm, in some cases from 0.2 μm to 2.0 μm. Because the grain structure is equiaxed (L/W=1) the grain length (L) is the same as the grain width. The improved aperture plate extends the life of nebulisers, eliminates the risk of premature and unpredictable failure of a nebuliser in service, eliminates the risk of product returns from hospitals and patients, and eliminates the possible risk of fragments of the aperture plate breaking free from the nebulizer.
Abstract translation: 孔板由包含约89%钯和约11%镍的钯镍合金形成。 在孔板的整个厚度上存在通常细的基本上等轴晶粒微观结构。 平均晶粒宽度(W)在0.2μm至5.0μm的范围内,在一些情况下为0.2μm至2.0μm。 由于晶粒结构为等轴(L / W = 1),晶粒长度(L)与晶粒宽度相同。 改进的孔板延长了雾化器的寿命,消除了雾化器在使用过程中过早和不可预测的故障的风险,消除了医院和患者的产品返回风险,并消除了孔板破碎的可能性, 喷雾器。
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公开(公告)号:US12144923B2
公开(公告)日:2024-11-19
申请号:US17818549
申请日:2022-08-09
Applicant: Stamford Devices Limited
Inventor: Patrick Power
Abstract: An aerosol delivery system has a nebulizer and a humidifier providing a gas flow to the nebulizer. A controller varies humidity level of the gas flow to the nebulizer so that if the nebulizer is not operating it has about 100% humidity and it is operating the value is less to allow for the humidification effect of the nebulizer. The control may be achieved by dynamically varying proportions of flow through a dry branch and a humidification branch.
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公开(公告)号:US11905615B2
公开(公告)日:2024-02-20
申请号:US17808432
申请日:2022-06-23
Applicant: Stamford Devices Limited
Inventor: Hong Xu
IPC: C25D7/00 , B41J2/16 , C25D5/02 , C25D5/10 , C25D1/00 , C25D5/00 , A61M11/00 , C25D5/54 , B05B17/00 , C25D3/38 , C25D3/46 , C25D3/48 , C25D3/54 , C25D5/34 , C25D5/48
CPC classification number: C25D7/00 , A61M11/005 , B05B17/0646 , B41J2/162 , B41J2/1625 , B41J2/1629 , B41J2/1631 , C25D1/003 , C25D3/38 , C25D3/46 , C25D3/48 , C25D3/54 , C25D5/022 , C25D5/10 , C25D5/34 , C25D5/48 , C25D5/54 , C25D5/611
Abstract: In one embodiment, a method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described according to other embodiments.
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公开(公告)号:US20230321368A1
公开(公告)日:2023-10-12
申请号:US17818549
申请日:2022-08-09
Applicant: Stamford Devices Limited
Inventor: Patrick POWER
CPC classification number: A61M11/02 , A61M11/00 , A61M16/024 , A61M16/16 , A61M16/161 , A61M11/06
Abstract: An aerosol delivery system has a nebulizer and a humidifier providing a gas flow to the nebulizer. A controller varies humidity level of the gas flow to the nebulizer so that if the nebulizer is not operating it has about 100% humidity and it is operating the value is less to allow for the humidification effect of the nebulizer. The control may be achieved by dynamically varying proportions of flow through a dry branch and a humidification branch.
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公开(公告)号:US11759581B2
公开(公告)日:2023-09-19
申请号:US16857701
申请日:2020-04-24
Applicant: Stamford Devices Limited
Inventor: Patrick Joseph Power , Jimmy Eaton-Evans
CPC classification number: A61M11/02 , A61M15/0021 , A61M15/0085 , A61M16/06 , A61M16/208 , A61M11/003 , A61M2202/0208 , A61M2202/04
Abstract: A system for delivery of aerosol therapy includes a housing defining a chamber. The housing has a base, a top and a main body extending therebetween. An ambient air inlet is adjacent the base and is normally closed by an inlet valve. The housing has a patient port. Exhaled air is exhausted through valves in a mouthpiece or a face mask to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port. A boss extends upwardly from the base and is spaced-apart inwardly of the main body of the housing to define a reception space or well.
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公开(公告)号:US11672939B2
公开(公告)日:2023-06-13
申请号:US16749024
申请日:2020-01-22
Applicant: Stamford Devices Limited
Inventor: John Sylvester Power , James B. Fink , Conor Paul Duffy , Trevor Stephen Fahy
IPC: A61M16/00 , A61M16/14 , A61M15/00 , A61M11/00 , A61M16/06 , A61M16/08 , A61M16/16 , B05B12/08 , B05B17/00 , B05B17/06
CPC classification number: A61M16/14 , A61M11/002 , A61M11/003 , A61M11/005 , A61M15/0085 , A61M16/0057 , A61M16/0666 , A61M16/0672 , A61M16/0833 , A61M16/0875 , A61M16/147 , A61M16/16 , A61M16/0808 , A61M2202/0208 , A61M2206/14 , B05B12/081 , B05B17/0646 , B05B17/0669
Abstract: A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 10, 20, which sits in the circuit from the supplemental oxygen supply and optional humidifier. The supplemental oxygen passes through this chamber 10, 20 in which the aerosol is located, and collects the aerosol transporting it to a patient via a nasal cannula 3 or a face mask 4. An aerosol generator 9 is mounted to the housing 10, 20 and delivers aerosol into an oxygen stream 13 flowing between an inlet 14 and an outlet 15 of the housing 10. The housing 10 also has a removable plug 16 in the base 17 thereof for draining any liquid that accumulates in the housing 10. There is no disruption of oxygen delivery to patients using nasal cannulas who currently have to use a separate face-mask when receiving nebulized medication.
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公开(公告)号:US11654448B2
公开(公告)日:2023-05-23
申请号:US16756204
申请日:2018-11-27
Applicant: STAMFORD DEVICES LIMITED
Inventor: Michael Aherne , Colga Coye , Philip Scanlon
CPC classification number: B05B17/0646
Abstract: An aperture plate (1) is attached at its rim (203) to a support washer (3) by adhesive. Anchor grooves (204) having a zig-zag pattern in plan are machined in the lower surface of the rim (203 of the aperture plate before application of the adhesive. The grooves (204) extend out to the edge of the aperture plate (1). The anchor grooves have a depth in the range of 10 μm to 40 μm, and a width in the range of 20 μm to 150 μm, and an angular pitch in the range of 2.5° to 12.5°. Excellent bonding strength is achieved for long term reliable attachment in an environment of high frequency vibration and moisture and chemical corrosion.
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公开(公告)号:US20230044607A1
公开(公告)日:2023-02-09
申请号:US17888334
申请日:2022-08-15
Applicant: Stamford Devices Limited
Inventor: Brendan HOGAN , Kieran HYLAND , Anthony REDMOND
Abstract: An aerosol generator with electrical power conducting pins has a vibratable plate with apertures therein and an annular piezo. An annular support member supports the piezo and the vibratable plate. A first electrical power conducting pin engages directly with a first, top, surface of the piezo. A second electrical power conducting pin indirectly conducts electrical power to a second surface of the piezo, by contacting an extension tab. There is a film of cured epoxy adhesive on the tab. The aerosol generator avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the same lateral and top side of the piezo and support member. The pins may have multi-point tips for particularly effective electrical contact.
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公开(公告)号:US11534559B2
公开(公告)日:2022-12-27
申请号:US16118668
申请日:2018-08-31
Applicant: Stamford Devices Limited
Inventor: Patrick Joseph Power , Jimmy Eaton-Evans
Abstract: A system for delivery of aerosol therapy to spontaneously breathing patients comprises a housing which defines a chamber. The housing has a base, a top and a main body extending between the base and the top. An ambient air inlet is located adjacent to the base and is normally closed by an inlet valve. The housing also has a patient port for receiving a mouthpiece or a face mask. The mouthpiece has an exhaust outlet closed by an exhaust valve. Similarly, the face mask has an exhaust outlet closed by an exhaust valve. Exhaled air is exhausted through the valves and to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing also has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port. A boss extends upwardly from the base and is spaced-apart inwardly of the main body of the housing to define a reception space or well.
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公开(公告)号:US11446695B2
公开(公告)日:2022-09-20
申请号:US17227559
申请日:2021-04-12
Applicant: Stamford Devices Limited
Inventor: Brendan Hogan , Kieran Hyland , Anthony Redmond
Abstract: An aerosol generator has a vibratable plate with apertures therein and an annular piezo which causes movement of the vibratable plate. An annular support member supports the piezo and the vibratable plate. A first electrical power conducting pin engages directly with a first, top, surface of the piezo. A second electrical power conducting pin indirectly conducts electrical power to a second surface of the piezo, by contacting an extension tab of the support member, also on its top side. There is a film of cured epoxy adhesive on the tab, providing excellent gripping force between the pin and the support. The aerosol generator avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the same lateral and top side of the piezo and support member. The pins may have multi-point tips for particularly effective electrical contact.
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