-
公开(公告)号：US20240041798A1
公开(公告)日：2024-02-08
申请号：US18462648
申请日：2023-09-07
Applicant: The Cleveland Clinic Foundation
Inventor： Vincent K. Tuohy , Suparna Mazumder , Justin M. Johnson
IPC: A61K31/138 , A61K31/337 , A61K31/555 , A61K31/7068 , A61K31/4745 , A61K31/675 , A61K31/502 , A61K31/7048 , A61K31/7064 , A61K31/4985 , A61K31/4196 , A61K45/06 , A61K31/704 , A61K33/243 , A61P35/00 , A61K39/00
CPC classification number: A61K31/138 , A61K31/337 , A61K31/555 , A61K31/7068 , A61K31/4745 , A61K31/675 , A61K31/502 , A61K31/7048 , A61K31/7064 , A61K31/4985 , A61K31/4196 , A61K45/06 , A61K31/704 , A61K33/243 , A61P35/00 , A61K39/001102 , A61K2039/575 , A61K33/244
Abstract: Provided herein are methods, kits and compositions for the treatment and/or prevention of ovarian cancer through the induction of an immune response against Anti-Mullerian Hormone Receptor, Type II (AMHR2).
-
公开(公告)号：US11835503B2
公开(公告)日：2023-12-05
申请号：US17234229
申请日：2021-04-19
Applicant: The Cleveland Clinic Foundation
Inventor： Stanley L. Hazen , Zeneng Wang , Bruce S. Levison
IPC: G01N30/88 , C12Q1/18 , G01N33/68 , A61K31/4164 , A61K31/43 , A61K31/7036 , G01N30/72 , C12Q1/02 , A61K31/496
CPC classification number: G01N30/88 , A61K31/4164 , A61K31/43 , A61K31/496 , A61K31/7036 , C12Q1/025 , C12Q1/18 , G01N33/6893 , G01N30/7233 , G01N2030/8813 , G01N2030/8822 , G01N2800/04 , G01N2800/042 , G01N2800/044 , G01N2800/32 , G01N2800/323 , G01N2800/50 , G01N2800/52
Abstract: The present invention provides markers and methods for determining whether a subject, particularly a human subject, has or is at risk of developing, a disease such as cardiovascular disease, diabetes mellitus, insulin resistance, metabolic syndrome, NAFLD (Nonalcoholic Fatty Liver Disease) or NASH (Nonalcoholic Steatohepatitis) (e.g., within the ensuing year, two years, and/or three years). The present application also relates to the use of such markers and methods for monitoring the status of such diseases in a subject or the effects of therapeutic agents on subjects with such diseases.
-
公开(公告)号：US11786489B2
公开(公告)日：2023-10-17
申请号：US17404025
申请日：2021-08-17
Applicant: The Cleveland Clinic Foundation
Inventor： Vincent K. Tuohy , Suparna Mazumder , Justin M. Johnson
IPC: A61K31/138 , A61K31/337 , A61K31/555 , A61K31/7068 , A61K31/4745 , A61K31/675 , A61K31/502 , A61K31/7048 , A61K31/7064 , A61K31/4985 , A61K31/4196 , A61K45/06 , A61K31/704 , A61K33/243 , A61P35/00 , A61K39/00 , A61K33/244
CPC classification number: A61K31/138 , A61K31/337 , A61K31/4196 , A61K31/4745 , A61K31/4985 , A61K31/502 , A61K31/555 , A61K31/675 , A61K31/704 , A61K31/7048 , A61K31/7064 , A61K31/7068 , A61K33/243 , A61K39/001102 , A61K45/06 , A61P35/00 , A61K33/244 , A61K2039/575 , A61K2300/00 , A61K31/555 , A61K2300/00 , A61K31/675 , A61K2300/00 , A61K31/704 , A61K2300/00 , A61K31/7048 , A61K2300/00 , A61K31/7068 , A61K2300/00 , A61K33/24 , A61K2300/00 , A61K31/7064 , A61K2300/00 , A61K31/4985 , A61K2300/00
Abstract: Provided herein are methods, kits and compositions for the treatment and/or prevention of ovarian cancer through the induction of an immune response against Anti-Mullerian Hormone Receptor, Type II (AMHR2).
-
公开(公告)号：US20230285035A1
公开(公告)日：2023-09-14
申请号：US18120385
申请日：2023-03-11
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Guillermo Ortiz Blanco
IPC: A61B17/16
CPC classification number: A61B17/1635 , A61B2217/005
Abstract: A bone tissue collection device is provided with an exterior collection container and a porous interior filter container. The device includes a lid having an upper face and is configured to releaseably seal the exterior collection container and interior filter container. A suction inlet tube and a suction outlet tube are operably coupled to the lid and angled from the upper face of the lid.
-
公开(公告)号：US20230263998A1
公开(公告)日：2023-08-24
申请号：US18111138
申请日：2023-02-17
Applicant: The Cleveland Clinic Foundation
Inventor： Charles Martin, III , Mark A. Miller
CPC classification number: A61M25/02 , A61B46/10 , A61M25/0009 , A61M2025/0253
Abstract: A medical assembly includes a sheath having a channel that extends therethrough; a medical device that extends into the channel of the sheath via a proximal end of the sheath; and a cover at least partially enclosing a space and having a first opening that provides access to the space, wherein the sheath extends through the first opening such that the medical device emerges from the proximal end of the sheath within the space.
-
Patent Agency Ranking
公开(公告)号：US11696717B2
公开(公告)日：2023-07-11
申请号：US16676997
申请日：2019-11-07
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Mark J. Niebauer
IPC: A61B5/0452 , A61B5/0408 , A61B5/00 , G06N20/20 , A61B5/349 , A61B5/25
CPC classification number: A61B5/349 , A61B5/25 , A61B5/7225 , A61B5/7275 , G06N20/20
Abstract: Systems and methods are provided for evaluating infranodal pacing is applied to a patient. Electrocardiogram (ECG) data representing the pacing is obtained from a set of electrodes as an ECG lead. A predictor value representing a frequency content a portion of the ECG lead is extracted. A fitness parameter is determined for the pacing from at least the predictor value. The fitness parameter represents a likelihood that the applied infranodal pacing will induce left ventricular dysfunction in the patient. The fitness parameter is displayed to a user at an associated display.
-
公开(公告)号：US11691280B2
公开(公告)日：2023-07-04
申请号：US17157693
申请日：2021-01-25
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Robb Colbrunn , Tara Nagle , Callan Gillespie
CPC classification number: B25J9/1633 , B25J9/1638 , B25J9/1653 , B25J9/1664 , B25J13/085 , B25J13/088 , B25J13/089
Abstract: An object can be moved via a robotic system with a combination of force and position control. The control system can include the object to be moved, the robotic system that moves the object, at least one force sensor, at least one position sensor, and a controller. A position control output, a force control output, and a hybrid weighting value can each be determined by the controller based on sensor data and then combined to determine an amount of position control and/or force control to be applied to move the object and/or modify an object in motion's trajectory.
-
28.发明公开公开(公告)号：US20230184804A1
公开(公告)日：2023-06-15
申请号：US18108738
申请日：2023-02-13
Inventor： George F. Muschler , James K. Monnich , Edward J. Kwee , Kimerly A. Powell , Edward E. Herderick , Cynthia A. Boehm , Thomas R. Adams , Robert Germanoski , Frank Krakosh, III , James Dunn , Daniel Bantz
CPC classification number: G01N35/1011 , C12M41/48 , B01L9/56 , B01L3/0262 , G01B11/0608 , G01B11/14 , B01L2300/0654 , G01N2035/1013
Abstract: Systems and methods provide for detection and controlled interaction with one or more objects. The system can include an imaging subsystem (20), a tool subsystem (26) containing one or more tools, a stage subsystem (16) and a control system (40). The control system (40) can integrate controls for each of the other subsystems, which controls can be implement desired functions over a variety of process parameters to perform the controlled interaction.
-
29.发明公开公开(公告)号：US20230146428A1
公开(公告)日：2023-05-11
申请号：US17984624
申请日：2022-11-10
Inventor： Anant Madabhushi , Golnoush Asaeikheybari , Amogh Hiremath , Mina K. Chung , John Barnard
IPC: G06T7/33 , G06V10/44 , G06V10/764 , G06T7/00
CPC classification number: G06T7/33 , G06T7/0016 , G06V10/44 , G06V10/764 , G06T2207/10081 , G06T2207/20224 , G06T2207/30041 , G06T2207/30048 , G06T2207/30061 , G06T2207/30096 , G06T2207/30101
Abstract: Systems, methods, and apparatus are provided for generating an atlas image of a branched structure and predicting a likelihood of success of certain treatments based on the atlas image. In one example, a method includes registering a plurality of images of instances of a branched structure to generate an aligned image for a cohort, wherein the branched structure comprises a central structure and at least one primary branch connected to the central structure; for each primary branch of the branched structure, iteratively registering respective portions of a plurality of images containing the primary branch to generate an aligned image portion of the primary branch; and applying a control grid of the aligned image portion of the primary branch to respective image portions containing the central structure and the other primary branches prior to iteratively registering a next primary branch; and generating an atlas image for the cohort based on the aligned image portions.
-
公开(公告)号：US20230145832A1
公开(公告)日：2023-05-11
申请号：US17980164
申请日：2022-11-03
Applicant: The Cleveland Clinic Foundation , The United States Government as Represented by the Department of Veterans Affairs
Inventor： Paul D. Marasco , Jonathon S. Schofield , Courtney E. Shell , Zachary C. Thumser , Dylan Beckler , Jonathan Sakai
CPC classification number: A61M21/02 , A61M5/52 , A61M2021/0022
Abstract: A cognitive illusion of ownership over a proxy extremity (e.g. a hand) is provided by discordant touch and visual information to a user. While the user feels the touch on their real extremity, they see a corresponding touch on the proxy extremity. The user's internally modeled reality is then updated to move the felt location of the real extremity to the seen location of the proxy extremity. As a result, the user embodies the proxy extremity, thereby disembodying the real extremity. Pain associated with medical procedures performed on the real extremity is then mitigated. And because an epileptic brain is less stringent when resolving conflict between what is seen and what is felt, correlations in time or space can shift attribution of the sensation of the felt touch on the user's real extremity to the location of the proxy extremity. This can be helpful in treating and/or diagnosing epilepsy.
-
-
-
-
-
-
-
-
-
Search Results
1180
records
(took 0.032 seconds)
