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公开(公告)号：US20220266015A1
公开(公告)日：2022-08-25
申请号：US17694655
申请日：2022-03-14
Applicant: ELECTROCORE, INC
Inventor： Bruce J. Simon , Joseph P. Errico , John T. Raffle
Abstract: Devices, systems and methods for treating various disorders and medical conditions through noninvasive stimulation of a nerve. A system comprises a stimulator including an electrode configured to contact an outer skin surface of a patient and an energy source coupled to the housing, The energy source generates an electrical impulse and the stimulator transmits the electrical impulse from the electrode transcutaneously through an outer skin surface of the patient to a selected nerve within the patient. The system further includes an application on a mobile device that receives data from a remote source. The mobile device couples to the stimulator and the application causes the mobile device to transmit the data to the stimulator.
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公开(公告)号：US20210402173A1
公开(公告)日：2021-12-30
申请号：US17472061
申请日：2021-09-10
Applicant: ElectroCore, Inc.
Inventor： Bruce J. Simon , Joseph P. Errico , John T. Raffle
Abstract: Methods and devices for stimulating a nerve in a patient include emitting an electrical signal near a spinal nerve within the patient. The electrical signal is generated within the housing and comprises bursts of pulses. Each burst of pulses comprises a burst period and a constant period, Each burst period comprises 2 to 20 pulses and at least a portion of each constant period comprises zero pulses. At least one of the pulses has a duration of about 50 microseconds to about 1000 microseconds.
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公开(公告)号：US11141582B2
公开(公告)日：2021-10-12
申请号：US17010634
申请日：2020-09-02
Applicant: ElectroCore, Inc.
Inventor： Bruce J. Simon , Joseph P. Errico , John T. Raffle
Abstract: Methods and devices for stimulating a nerve in a patient include emitting an electrical signal near a spinal nerve within the patient such that the patient experiences at least some pain relief. The methods include varying an electric field such that burst periods and constant periods are created. The electric field has a charge that alternates between positive and negative during the burst periods and a charge with a magnitude of zero during the constant periods.
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公开(公告)号：US20210031026A1
公开(公告)日：2021-02-04
申请号：US17072392
申请日：2020-10-16
Applicant: ELECTROCORE, INC.
Inventor： Bruce J. Simon , Joseph P. Errico , John T. Raffle
Abstract: Devices and methods for non-invasive stimulation of nerves, such as the vagus nerve, include a housing and an electrode spaced from the housing. The electrode is configured to be positioned adjacent to, or in contact with, an outer skin surface of a patient. A source of energy is positioned within the housing and operably coupled to the electrode, either wirelessly or via a lead or other wired connection. The source of energy emits an electrical impulse to the electrode such that the electrical impulse passes through the outer skin surface of the patient to a nerve at a target region in the patient sufficient to modulate the nerve. The electrical impulse comprises bursts each with a frequency from about 1 Hz to about 100 Hz, wherein each of the bursts comprises 2 pulses to 20 pulses.
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25.发明申请公开(公告)号：US20200171304A1
公开(公告)日：2020-06-04
申请号：US16356376
申请日：2019-03-18
Applicant: ElectroCore, Inc.
Inventor： Bruce J. Simon , Joseph P. Errico , John T. Raffle
Abstract: Transcutaneous electrical and magnetic nerve stimulation devices are disclosed, along with methods of treating lower urinary tract disorders using energy that is delivered noninvasively by the devices. The disorders comprise overactive bladder, urge incontinence, stress, incontinence, urge frequency, non-obstructive urinary retention and interstitial cystitis/painful bladder syndrome. In embodiments of the disclosed methods, a posterior tibial nerve of a patient is stimulated non-invasively. Methods are disclosed for selecting protocol parameters for a nerve stimulation session for treating each individual patient, wherein modules of the bladder of the patient are represented as coupled non-linear oscillators.
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Patent Agency Ranking
26.发明申请公开(公告)号：US20200054872A1
公开(公告)日：2020-02-20
申请号：US16662140
申请日：2019-10-24
Applicant: ElectroCore, Inc.
Inventor： Bruce J. Simon , Joseph P. Errico , John T. Raffle
Abstract: Devices, systems and methods are disclosed for treating or preventing an autism spectrum disorder, a pervasive developmental disorder, or a disorder of psychological development. The methods comprise transmitting impulses of energy non-invasively to selected nerve fibers, particularly those in a vagus nerve. The nerve stimulation may be used as a behavior conditioning tool, by producing euphoria in an autistic individual. Vagus nerve stimulation is also used to modulate circulating serotonin levels in a pregnant woman so as to reduce the risk of having an autistic child; modulate the levels of growth factors within a child; promote balance of neuronal excitation/inhibition; modulate the activity of abnormal resting state neuronal networks; increase respiratory sinus arrhythmia; and avert episodes of motor stereotypies with the aid of forecasting methods.
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公开(公告)号：US20200053487A1
公开(公告)日：2020-02-13
申请号：US16598009
申请日：2019-10-10
Applicant: ElectroCore, Inc.
Inventor： Bruce J. Simon , Joseph P. Errico , John T. Raffle
IPC: H04R25/00
Abstract: Non-invasive electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including sinus symptoms that resemble an immune-mediated response (“sinus” headaches), irrespective of whether those symptoms arise from an allergy that is co-morbid with the headache. The disclosed methods may also be used to treat other disorders that may be co-morbid with migraine headaches, such as anxiety disorders.
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28.发明申请公开(公告)号：US20200046973A1
公开(公告)日：2020-02-13
申请号：US16599285
申请日：2019-10-11
Applicant: ElectroCore, Inc.
Inventor： Bruce J. Simon , Joseph P. Errico , John T. Raffle
Abstract: Devices, systems and methods are disclosed for treating or preventing gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders. The devices comprise a housing and an energy source for generating an electric current and transmitting the electric current from the electrode through an interface and the outer skin surface of the patient to a selected nerve fiber within the patient as the interface contacts the outer skin surface. The electric current is sufficient to modulate the selected nerve fiber to at least one of treat or prevent at least one of gastroparesis, functional dyspepsia, or ileus in the patient.
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公开(公告)号：US20250082924A1
公开(公告)日：2025-03-13
申请号：US18960398
申请日：2024-11-26
Applicant: ElectroCore, Inc.
Inventor： Bruce J. Simon , Joseph P. Errico , John T. Raffle
Abstract: Devices and methods for the non-invasive stimulation of nerves, such as the vagus nerve, include a housing and an electrode coupled to the housing. The electrode is configured to be positioned adjacent to, or in contact with, an outer skin surface of a patient. A source of energy is coupled to the housing and operably coupled to the electrode. The source of energy emits an electrical impulse to the electrode such that the electrical impulse passes through the outer skin surface of the patient to a nerve at a target region in the patient sufficient to modulate the nerve. The electrical impulse comprises burst periods and constant periods, wherein each burst period includes 2 to 20 pulses and has a duration of less than 20,000 microseconds
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公开(公告)号：US11944815B2
公开(公告)日：2024-04-02
申请号：US17522010
申请日：2021-11-09
Applicant: electroCore, Inc.
Inventor： Bruce J. Simon , Joseph P. Errico , John T. Raffle
IPC: A61N1/36 , G06Q10/10 , G16H20/30 , G16H20/40 , G16H40/20 , A61B5/00 , A61N1/04 , A61N1/372 , A61N1/40 , A61N2/00 , A61N2/02
CPC classification number: A61N1/36021 , A61N1/36034 , G06Q10/10 , G16H20/30 , G16H20/40 , G16H40/20 , A61B5/4836 , A61B2560/0456 , A61N1/0456 , A61N1/37235 , A61N1/40 , A61N2/006 , A61N2/008 , A61N2/02
Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as headache, by noninvasive stimulation of a nerve. A system comprises a stimulator having an interface configured to contact an outer skin surface of a patient and an energy source coupled to the interface. The energy source transmits an electrical impulse through the interface transcutaneously through the outer skin surface of the patient to a nerve of the patient such that the nerve is modulated. The system further comprises a mobile device coupled to the stimulator to transmit data to the stimulator. The data includes a therapy regimen to reduce one or more symptoms of a headache in the patient.
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