公开(公告)号：US20170071470A1

公开(公告)日：2017-03-16

申请号：US14854330

申请日：2015-09-15

Applicant: Siemens Healthcare GmbH

Inventor： Hasan E. Cetingul ,  Benjamin L. Odry ,  Mariappan S. Nadar

IPC: A61B5/00 ,  G06F19/00 ,  A61B5/055

CPC classification number: A61B5/0042 ,  A61B5/0013 ,  A61B5/0037 ,  A61B5/055 ,  A61B5/08 ,  A61B5/201 ,  A61B5/4064 ,  A61B5/7267 ,  A61B2576/026 ,  G16H50/50

Abstract: A computer-implemented method for identifying abnormalities in Magnetic Resonance (MR) brain image data includes a computer receiving multi-contrast MR image data of a subject's brain and identifying, within the multi-contrast MR image data, (i) an abnormality region comprising one or more suspected abnormalities and (ii) a healthy region comprising healthy tissue. The computer creates a model of the healthy region, computes a novelty score for each voxel in the multi-contrast MR image data based on the abnormality region and the model, and creates an abnormality map of the subject's brain based on the novelty score computed for each voxel in the multi-contrast MR image data.

Abstract translation: 用于识别磁共振（MR）脑图像数据中的异常的计算机实现的方法包括接收受试者脑的多对比度MR图像数据的计算机，并且在多对比度MR图像数据内识别（i）异常区域，所述异常区域包括 一个或多个怀疑异常和（ii）健康区域，包括健康组织。 计算机创建健康区域的模型，基于异常区域和模型计算多对比度MR图像数据中的每个体素的新颖得分，并且基于为 每个体素在多对比度MR图像数据中。

公开(公告)号：US09560987B2

公开(公告)日：2017-02-07

申请号：US14125086

申请日：2012-08-15

Applicant: Nancy R. Rizzo

Inventor： Nancy R. Rizzo

IPC: A61B5/00 ,  A61B5/053 ,  A61B5/05 ,  H04N5/225 ,  A61B5/02 ,  A61B5/08 ,  A61B5/20

CPC classification number: A61B5/0533 ,  A61B5/0082 ,  A61B5/0093 ,  A61B5/02 ,  A61B5/05 ,  A61B5/08 ,  A61B5/201 ,  A61B5/42 ,  A61B5/4842 ,  A61B5/6825 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/7275 ,  G06F19/00 ,  H04N5/2256

Abstract: Spatial light response around a fingertip or toe of a subject in response to electrical stimulation can be associated to a specified remote particular body anatomy, location, component, or system such as for providing a particularized physiological status indicator or other particularized response indication that is particular to the specified particular body anatomy, location, component, or system.

Abstract translation: 响应于电刺激而围绕对象的指尖或脚趾的空间光响应可以与指定的远程特定身体解剖结构，位置，组件或系统相关联，例如用于提供特定生理状态指示符或其他特定化的响应指示 到指定的特定身体解剖结构，位置，部件或系统。

公开(公告)号：US20170027460A1

公开(公告)日：2017-02-02

申请号：US15204349

申请日：2016-07-07

Applicant: NeuroMedic, Inc.

Inventor： Jin Shimada ,  Harry A. Puryear ,  Gregory G. Brucker

IPC: A61B5/04 ,  A61B5/00 ,  A61B18/14 ,  A61B5/20

CPC classification number: A61B5/04001 ,  A61B5/201 ,  A61B5/4035 ,  A61B5/4836 ,  A61B5/6876 ,  A61B5/725 ,  A61B18/1492 ,  A61B18/1815 ,  A61B2018/00023 ,  A61B2018/00267 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1407 ,  A61B2018/1467 ,  A61B2018/162 ,  A61B2018/1861 ,  A61B2562/0209 ,  A61B2562/028 ,  A61B2562/043

Abstract: An intraluminal microneurography probe has a probe body that is configured to be introduced into an artery near an organ of a body without preventing the flow of blood through the artery. An expandable sense electrode and an expandable stimulation electrode are fixed to the probe body at one end of each electrode such that movement of the other end toward the fixed end causes the sense electrode to expand from the probe body toward a wall of the artery. A ground electrode is configured to couple to the body, and a plurality of electrical connections are operable to electrically couple the electrodes to electrical circuitry. The sense electrode is operable to measure sympathetic nerve activity in response to excitation of the stimulation electrode. An ablation element is located between the expandable sense electrode and expandable stimulation electrode, and is operable to ablate nerves proximate to the artery.

Abstract translation: 管腔内微量测微探针具有探针体，其被配置成被引入身体器官附近的动脉，而不阻止血液通过动脉流动。 可扩展感测电极和可膨胀的刺激电极在每个电极的一端固定到探针主体，使得另一端朝向固定端的运动导致感测电极从探针体朝向动脉的壁膨胀。 接地电极被配置为耦合到主体，并且多个电连接可操作以将电极电耦合到电路。 感测电极可操作以响应于刺激电极的激发来测量交感神经活动。 消融元件位于可扩张感测电极和可膨胀的刺激电极之间，并且可操作以消融靠近动脉的神经。

公开(公告)号：US20160287325A1

公开(公告)日：2016-10-06

申请号：US15085786

申请日：2016-03-30

Applicant: Medtronic Ardian Luxembourg S.a.r.l.

Inventor： Dwayne S. Yamasaki ,  Bryan Courtney ,  Wenjeng Li ,  Kevin Mauch ,  Kevin McFarlin ,  Gabriel Brennan ,  David Gannon ,  David Hobbins ,  Brian Kelly ,  Stephen Nash ,  Matthew Bonner ,  Sean Ward

IPC: A61B18/14 ,  A61B18/02 ,  A61N1/36 ,  A61N1/05 ,  A61B5/04 ,  A61B5/00

CPC classification number: A61N1/36125 ,  A61B5/04001 ,  A61B5/201 ,  A61B5/4035 ,  A61B5/4041 ,  A61B5/4833 ,  A61B5/4893 ,  A61B5/6853 ,  A61B5/6856 ,  A61B18/02 ,  A61B18/1492 ,  A61B2018/0022 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00654 ,  A61B2018/00839 ,  A61B2018/0212 ,  A61B2018/1407 ,  A61B2018/1435 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/36017 ,  A61N1/3605 ,  A61N1/36117 ,  A61N1/36171 ,  A61N1/36175

Abstract: Endovascular nerve monitoring devices and associated systems and methods are disclosed herein. A nerve monitoring system configured in accordance with a particular embodiment of the present technology can include a shaft having a proximal portion and a distal portion and a nerve monitoring assembly at the distal portion. The shaft is configured to locate the distal portion intravascularly at a treatment site. The nerve monitoring assembly can include a bipolar stimulation electrode array and a bipolar recording electrode array disposed distal to the bipolar stimulation electrode assembly.

公开(公告)号：US20160120473A1

公开(公告)日：2016-05-05

申请号：US14816714

申请日：2015-08-03

Applicant: Attends Healthcare Products, Inc.

Inventor： Steven D. Linton ,  Kevin Koski

IPC: A61B5/00 ,  A61B5/20 ,  A61B5/145

CPC classification number: A61B5/6808 ,  A61B5/0024 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/20 ,  A61B5/201 ,  A61B5/208 ,  A61B5/746 ,  A61F13/42 ,  A61F13/49

Abstract: A diagnostic sheet for use in conjunction with a disposable absorbent garment is disclosed. The diagnostic sheet may be operable to wick fluid vertically, and includes one or more diagnostic elements and a radio frequency identification device (RFID). The one or more diagnostic elements may be integrated with the diagnostic sheet and positioned at a first region of the diagnostic sheet, and the RFID may be integrated with the diagnostic sheet and positioned proximate the first region. In the presence of the fluid, each of the one or more diagnostic elements may be configured to indicate a result of a particular diagnostic test. In the presence of the fluid, the RFID may be configured to provide an indication that the fluid wicked by the diagnostic sheet has reached the one or more diagnostic elements.

Abstract translation: 公开了一种与一次性吸收衣服结合使用的诊断片材。 诊断片可以用于垂直地吸液，并且包括一个或多个诊断元件和射频识别装置（RFID）。 一个或多个诊断元件可以与诊断片材集成并且位于诊断片材的第一区域，并且RFID可以与诊断片材集成并且定位在第一区域附近。 在存在流体的情况下，一个或多个诊断元件中的每一个可以被配置为指示特定诊断测试的结果。 在存在流体的情况下，RFID可以被配置为提供由诊断片所恶化的流体到达一个或多个诊断元件的指示。

公开(公告)号：US20160100802A1

公开(公告)日：2016-04-14

申请号：US14895219

申请日：2014-11-30

Applicant: SCR ENGINEERS LTD

Inventor： Elizabeth NEWMAN

IPC: A61B5/00 ,  A61B5/117 ,  A61B5/20 ,  A61B5/11 ,  A01K29/00 ,  A61B5/0205

CPC classification number: A61B5/6831 ,  A01K29/005 ,  A61B5/0022 ,  A61B5/02055 ,  A61B5/02438 ,  A61B5/082 ,  A61B5/0823 ,  A61B5/1123 ,  A61B5/113 ,  A61B5/117 ,  A61B5/165 ,  A61B5/201 ,  A61B5/4255 ,  A61B5/4266 ,  A61B5/4806 ,  A61B5/4812 ,  A61B5/7282 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/746 ,  A61B2503/40 ,  A61B2560/0242 ,  A61B2562/0219 ,  G06F19/3418 ,  G16H10/60

Abstract: A system for behavioral monitoring for equines, comprising at least one sensor to measure a signal related to the equine, a database to store at least one parameter of the equine as a function of time, and processing means. The sensor is in communication with the equine, and comprises a wireless transmitter which is in communication with the data-base. The processing means, in communication with the database, is adapted to (i) determine, from at least one signal from the at least one sensor, at least one parameter of the equine as a function of time; (ii) establish normal behavior of the equine based on the parameter; and (iii) identify at least one abnormal behavior of the equine by identifying at least one deviation from normal behavior.

Abstract translation: 一种用于马的行为监测系统，包括至少一个传感器以测量与马相关的信号，数据库用于存储马的至少一个参数作为时间的函数，以及处理装置。 传感器与马通信，并且包括与数据库通信的无线发射器。 与数据库通信的处理装置适于（i）从至少一个传感器的至少一个信号确定马的至少一个参数作为时间的函数; （ii）根据参数建立马的正常行为; 和（iii）通过识别与正常行为的至少一个偏差来识别马的至少一个异常行为。

公开(公告)号：US20160081744A1

公开(公告)日：2016-03-24

申请号：US14956350

申请日：2015-12-01

Applicant: SYMAP HOLDING LIMITED

Inventor： Jie WANG

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B5/0205 ,  A61B5/0215 ,  A61B5/024 ,  A61B5/04001 ,  A61B5/201 ,  A61B5/4833 ,  A61B5/4836 ,  A61B5/4893 ,  A61B5/6853 ,  A61B18/18 ,  A61B2018/00202 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00791 ,  A61B2018/00839 ,  A61B2018/00875 ,  A61B2018/1407 ,  A61B2018/1435 ,  A61B2018/1475 ,  A61N1/36117

Abstract: Disclosed herein are systems and methods for locating and identifying nerves innervating the wall of arteries such as the renal artery. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The methods includes evaluating a change in physiological parameters after energy is delivered to an arterial wall; and determining the type of nerve that the energy was directed to (sympathetic or parasympathetic or none) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions.

Abstract translation: 本文公开了用于定位和识别神经支配于诸如肾动脉的动脉壁的系统和方法。 本发明识别血管壁上神经支配的区域; 提供能量准确地传递到目标神经的指示; 并提供对神经递送的能量的影响的即时的程序后评估。 所述方法包括在能量被传送到动脉壁之后评估生理参数的变化; 并根据评估结果确定能量指向的神经类型（交感神经或副交感神经或无副作用）。 该系统至少包括用于将能量传递到血管壁的装置; 用于检测来自受试者的生理信号的传感器; 和显示使用所述方法获得的结果的指标。 还提供了用于执行映射和消融功能的导管。

公开(公告)号：US20160058606A1

公开(公告)日：2016-03-03

申请号：US14685415

申请日：2015-04-13

Applicant: The Sydney Children's Hospitals Network (Randwick and Westmead) ,  The University of Sydney

Inventor： Patrina Ha Yuen Caldwell ,  Michael Lance Dickinson ,  James Charles Kerr McCauley ,  Geoffrey Gordon Wickham

IPC: A61F5/48 ,  G08B21/20 ,  A61B7/00 ,  A61B5/11 ,  A61B5/00

CPC classification number: A61F5/48 ,  A61B5/0002 ,  A61B5/11 ,  A61B5/20 ,  A61B5/201 ,  A61B5/4557 ,  A61B5/4806 ,  A61B5/68 ,  A61B5/682 ,  A61B5/6887 ,  A61B7/006 ,  A61F5/56 ,  A61F2005/563 ,  G08B21/04 ,  G08B21/20

Abstract: A system (10) and method for use by a subject with a sleep disorder, such as nocturnal enuresis. The system (10) comprises at least one sensor (11) that detects at least one attribute of the sleep disorder, for example urine, and outputs at least a first signal on or after detection of that attribute. The system (10) further comprises a control device (12) that comprises an arousal device (14), such as a loudspeaker, that activates on or after receipt of the first signal, an interactive device (15) that is actuable by the subject to deactivate or modify the operation of the arousal device (14) and an output device (16) for delivering an output to the subject. The output being delivered on or after deactivation or modification of the arousal device (14).

Abstract translation: 用于患有睡眠障碍（例如夜间遗尿）的受试者的系统（10）和方法。 系统（10）包括至少一个检测睡眠障碍的属性（例如尿）的传感器（11），并且在检测到该属性之后或之后输出至少第一信号。 所述系统（10）还包括控制装置（12），所述控制装置（12）包括在接收到所述第一信号之后或之后激活的唤醒装置（14），所述唤醒装置（14）在所述第一信号接收之后激活， 以去激活或修改唤醒装置（14）的操作和用于将输出传送到对象的输出装置（16）。 所述输出在所述觉醒装置（14）的去激活或修改之后或之后递送。

公开(公告)号：US20150359475A1

公开(公告)日：2015-12-17

申请号：US14742272

申请日：2015-06-17

Applicant: Kevin Michael Bennett ,  Scott Charles Beeman

Inventor： Kevin Michael Bennett ,  Scott Charles Beeman

IPC: A61B5/20 ,  G01R33/48 ,  A61K49/14 ,  G01R33/56 ,  A61B5/055 ,  A61B5/00

CPC classification number: A61B5/201 ,  A61B5/055 ,  A61B5/4222 ,  A61K49/14 ,  G01R33/5601 ,  G01R33/5608

Abstract: Systems and methods for noninvasively determining the function capacity of the kidney are provided. In the methods, first contrast agent is injected into the vasculature of a subject. The contrast agent is to be bound with functioning glomeruli of the kidney of the subject. Then, the kidney is imaged with a magnetic resonance imaging (MRI) system to acquire MRI images of the kidney. In the images, signal magnitudes or phases of voxels of regions bound with the contrast agent are different from signal magnitudes or phases of voxels of regions not bound with the contrast agent. Afterwards, the function capacity of the kidney is determined using the MRI images. Lastly, a report of the function capacity of the kidney is generated.

Abstract translation: 提供了非侵入式确定肾功能能力的系统和方法。 在该方法中，将第一造影剂注射到受试者的脉管系统中。 造影剂与受试者肾脏的功能性肾小球结合。 然后，用磁共振成像（MRI）系统对肾脏进行成像以获得肾脏的MRI图像。 在图像中，与造影剂结合的区域的体素的信号幅度或相位不同于未与造影剂结合的区域的体素的信号幅度或相位。 然后，使用MRI图像确定肾脏的功能能力。 最后，产生肾功能能力报告。

公开(公告)号：US09186212B2

公开(公告)日：2015-11-17

申请号：US13840244

申请日：2013-03-15

Applicant: St. Jude Medical, Cardiology Division, Inc.

Inventor： Yelena Nabutovsky ,  Edward Karst ,  Xiaoyi Min ,  Stuart Rosenberg ,  Kritika Gupta

IPC: A61B18/00 ,  A61B18/14 ,  A61B5/053 ,  A61B5/00 ,  A61B8/06 ,  A61B5/026 ,  A61B5/20

CPC classification number: A61B18/1492 ,  A61B5/0261 ,  A61B5/0538 ,  A61B5/201 ,  A61B5/4848 ,  A61B8/06 ,  A61B2018/00863

Abstract: A renal denervation system includes a renal denervation catheter and a flow determining system. The renal denervation catheter includes a plurality of ablation members positioned at a distal end portion thereof. The renal denervation catheter is insertable into a renal artery. The flow determining system includes a processor and first and second flow determining members spaced apart on the renal denervation catheter. The processor is configured to determine a change in blood flow through the renal artery resulting from a renal denervation procedure using the renal denervation catheter in response to input from the first and second flow determining members.

Abstract translation: 肾去神经支配系统包括肾去神经支配导管和流动确定系统。 肾去神经管导管包括定位在其远端部分处的多个消融部件。 肾去神经支配导管可插入肾动脉。 流动确定系统包括处理器和在肾去神经支配导管间隔开的第一和第二流动确定构件。 处理器被配置为响应于来自第一和第二流动确定构件的输入，确定使用肾去神经支配导管的肾去神经过程导致的肾动脉的血流变化。