公开(公告)号：US08420026B2

公开(公告)日：2013-04-16

申请号：US13594293

申请日：2012-08-24

Applicant: Yoon-kyoung Cho ,  Jeong-gun Lee ,  Beom-seok Lee ,  Jong-myeon Park

Inventor： Yoon-kyoung Cho ,  Jeong-gun Lee ,  Beom-seok Lee ,  Jong-myeon Park

IPC: B04B13/00

CPC classification number: B01L3/502738 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0233 ,  B01L3/502753 ,  B01L3/502761 ,  B01L2300/0806 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/0409 ,  B01L2400/0677 ,  F16K99/0001 ,  F16K99/0017 ,  F16K99/0019 ,  F16K99/0032 ,  F16K99/004 ,  F16K2099/0076 ,  F16K2099/0084

Abstract: A centrifugal force-based microfluidic device for nucleic acid extraction and a microfluidic system are provided. The microfluidic device includes a body of revolution; a microfluidic structure disposed in the body of revolution, the microfluidic structure including a plurality of chambers, channels connecting the chambers, and valves disposed in the channels to control fluid flow, the microfluidic structure transmitting the fluid using centrifugal force due to rotation of the body of revolution; and magnetic beads contained in one of the chambers which collect a target material from a biomaterial sample flowing into the chamber, wherein the microfluidic structure washes the magnetic beads which collect the target material, and separates nucleic acid by electromagnetic wave irradiation from an external energy source to the magnetic beads. The microfluidic system includes the microfluidic device; a rotation operating unit which rotates the body of revolution; and an external energy source which irradiates electromagnetic waves.

Abstract translation: 提供了用于核酸提取的离心力微流体装置和微流体系统。 微流体装置包括一个革命体; 设置在旋转体内的微流体结构，所述微流体结构包括多个室，连接所述室的通道和设置在通道中的阀以控制流体流动，所述微流体结构由于所述体的旋转而使用离心力传递流体 的革命 以及包含在其中一个室中的磁珠，其从流入腔室的生物材料样品收集目标材料，其中微流体结构洗涤收集目标材料的磁珠，并通过来自外部能量源的电磁波照射分离核酸 到磁珠。 微流体系统包括微流体装置; 使旋转体旋转的旋转操作单元; 以及照射电磁波的外部能量源。

公开(公告)号：US20120292790A1

公开(公告)日：2012-11-22

申请号：US13544230

申请日：2012-07-09

Applicant: PATRICK J. TATERA

Inventor： PATRICK J. TATERA

IPC: B01F3/04

CPC classification number: B01F3/04801 ,  B01F15/0201 ,  B01F15/0224

Abstract: The carbonation device includes a cap system selectively mounted to the mouth of a liquid container. The cap system includes a cap, a rotatable control ring coaxial with and selectively attached to the cap, a reaction vessel selectively attached to the bottom of the cap, and an elongate distribution tube selectively mounted to the cap. The reaction vessel is filled with a preselected amount of carbonating material such that when the control ring is rotated in one position, water may be introduced into the vessel to initiate the carbonation reaction. In another position, the carbonating gas flows into the liquid via the distribution tube. Other rotated positions permit locking and unlocking of the control ring. The carbonation device also includes a drop-in configuration that serves as a self-contained carbonation distribution vessel.

Abstract translation: 碳酸化装置包括选择性地安装到液体容器的口部的盖系统。 盖系统包括盖，与盖同轴并选择性地附接到盖的可旋转控制环，选择性地附接到盖的底部的反应容器和选择性地安装到盖的细长分配管。 反应容器填充有预选量的碳酸化材料，使得当控制环在一个位置旋转时，可以将水引入容器中以引发碳酸化反应。 在另一位置，碳酸化气体经由分配管流入液体。 其他旋转位置允许控制环的锁定和解锁。 碳酸化装置还包括用作独立碳酸化分配容器的滴入构造。

公开(公告)号：US08308731B2

公开(公告)日：2012-11-13

申请号：US12202748

申请日：2008-09-02

Applicant: Arman H. Valaie

Inventor： Arman H. Valaie

IPC: A61B17/58

CPC classification number: B01F7/0005 ,  A61B17/8819 ,  A61B17/8822 ,  B01F7/00566 ,  B01F13/002 ,  B01F13/0023 ,  B01F15/0201 ,  B01F15/0203 ,  B01F15/0225 ,  B01F15/0237 ,  B01F15/0279

Abstract: In at least one embodiment of the present invention, a device for mixing and dispensing a bone cement mixture is provided. The device comprises an injector housing having a chamber for containing a first and a second bone cement component and a second housing having a chamber for containing a flexible wire mixing element. A plunger actuates within the chamber of the second housing to transfer the wire mixing element to the injector housing for mixing the first and second bone cement components to form the bone cement mixture. The plunger rotates the wire mixing element to mix the bone cement mixture. Thereafter, the wire mixing element is withdrawn from the injector housing and the injector housing is assembled with an injector handle. A plunger coupled to the injector handle advances through the injector chamber to dispense the bone cement mixture from the device.

Abstract translation: 在本发明的至少一个实施例中，提供了一种用于混合和分配骨水泥混合物的装置。 该装置包括具有用于容纳第一和第二骨水泥部件的室的注射器壳体和具有用于容纳柔性线混合元件的室的第二壳体。 柱塞在第二壳体的腔室内致动，以将钢丝混合元件转移到喷射器壳体，用于混合第一和第二骨水泥组分以形成骨水泥混合物。 柱塞旋转钢丝混合元件以混合骨水泥混合物。 此后，电线混合元件从注射器壳体中取出，并且注射器壳体与注射器手柄组装在一起。 联接到注射器手柄的柱塞前进通过注射器腔室以从装置分配骨水泥混合物。

公开(公告)号：US20120230146A1

公开(公告)日：2012-09-13

申请号：US13415327

申请日：2012-03-08

Applicant: Herbert Ungerechts ,  Hans-Jörg Frank ,  Christoph Schwemler ,  Reiner Horl ,  Hans-Jürgen Thiem ,  Markus Hagedorn

Inventor： Herbert Ungerechts ,  Hans-Jörg Frank ,  Christoph Schwemler ,  Reiner Horl ,  Hans-Jürgen Thiem ,  Markus Hagedorn

IPC: B01F15/02 ,  B01F15/00

CPC classification number: B01F5/244 ,  B01F15/00032 ,  B01F15/0201 ,  B08B9/0813 ,  B08B9/093 ,  B65D88/32 ,  B65D90/0093

Abstract: A mixing silo for free-flowing finely divided solid materials, in particular for powdered, fibrous and/or granular mixed material, especially polymer granules, specifically suited for mixing polymer granules, having an excellent mixing quality and at the same time a simplified and improved suitability for washing out in order to avoid cross contamination. The mixing silo may be used for homogenizing possibly inhomogeneous polymer granule batches in the form of a stream of product from a process producing polymer granules.

Abstract translation: 用于自由流动的细分固体材料的混合料仓，特别是用于粉末状，纤维状和/或颗粒状混合材料，特别是聚合物颗粒，特别适用于混合聚合物颗粒的聚合物颗粒，具有优异的混合质量，同时简化和改进 适合洗涤以避免交叉污染。 混合料仓可用于将来自产生聚合物颗粒的方法的产物流形式的可能不均匀的聚合物颗粒批料均化。

公开(公告)号：US20120028293A1

公开(公告)日：2012-02-02

申请号：US13269449

申请日：2011-10-07

Applicant: Achim Wixforth ,  Christoph Gauer

Inventor： Achim Wixforth ,  Christoph Gauer

IPC: C12Q1/02 ,  C12M1/02 ,  C12M3/00

CPC classification number: G01N29/222 ,  B01F11/0266 ,  B01F11/0283 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0263 ,  B01F2215/0037 ,  B01L3/502792 ,  B01L2300/0816 ,  B01L2300/089 ,  B01L2400/0433 ,  B01L2400/0436 ,  B01L2400/0496 ,  G01N1/40 ,  Y10T436/25 ,  Y10T436/2575

Abstract: The invention relates to a mixing method for mixing at least one small quantity of liquid, in which a quantity of liquid is applied, in a reaction region and at least one surface sound wave is reacted with the quantity of liquid. The invention relates further to a mixing device for mixing at least one quantity of liquid for performing the method of the present invention, a use of the device, and a method of analysis for bond strengths on surfaces.

Abstract translation: 本发明涉及一种混合方法，用于将至少一种少量液体（其中施加一定量的液体）混合在反应区域中，并且至少一个表面声波与液体量反应。 本发明还涉及用于混合至少一种量的用于实施本发明的方法的液体的混合装置，该装置的使用以及对表面上的结合强度进行分析的方法。

公开(公告)号：US07947126B2

公开(公告)日：2011-05-24

申请号：US11204083

申请日：2005-08-15

Applicant: Christopher M. Teeley ,  David Kassin ,  Douglas L. Cochran ,  Christopher B. Palmer ,  Norman E. Pratt

Inventor： Christopher M. Teeley ,  David Kassin ,  Douglas L. Cochran ,  Christopher B. Palmer ,  Norman E. Pratt

IPC: C08K5/00 ,  C09D11/00 ,  C09D11/06 ,  C11C3/00 ,  B01F13/00

CPC classification number: B01F15/0201 ,  B01F7/082 ,  B01F2015/0221 ,  C09B67/0021

Abstract: A method for preparing an organic pigment dispersion, such as a flush pigment or ink product, comprises steps of introducing into a twin screw extruder a stable, water-borne pigment dispersion, an organic medium, and a destabilizing agent; mixing together the stable, water-borne pigment dispersion, the organic medium, and the destabilizing agent to produce a pigment flush phase and a water phase; and removing at least a part of the water phase. A twin-screw extruder for carrying out the flushing method has an addition and flushing zone, a water removal zone, and a zone for rinsing the crude organic pigment dispersion or flush with water and removing the rinse water. Additional materials may be added to form a finished pigmented product such as an ink product, masterbatch, or toner.

Abstract translation: 制备有机颜料分散体如冲洗颜料或油墨产品的方法包括以下步骤：向双螺杆挤出机中引入稳定的水性颜料分散体，有机介质和不稳定剂; 将稳定的水性颜料分散体，有机介质和去稳定剂混合在一起以产生颜料冲洗相和水相; 并除去水相的至少一部分。 用于进行冲洗方法的双螺杆挤出机具有添加和冲洗区域，除水区域和用于漂洗粗有机颜料分散体或与水冲洗并除去冲洗水的区域。 可以添加另外的材料以形成成品着色产品，例如油墨产品，母料或调色剂。

公开(公告)号：US20110113972A1

公开(公告)日：2011-05-19

申请号：US12591407

申请日：2009-11-18

Applicant: Patrick J. Tatera

Inventor： Patrick J. Tatera

IPC: B67D1/04 ,  B01F3/04

CPC classification number: B01F3/04801 ,  B01F15/0201 ,  B01F15/0224

Abstract: The carbonation device includes a cap system selectively mounted to the mouth of a liquid container. The cap system includes a cap, a rotatable control ring coaxial with and selectively attached to the cap, a reaction vessel selectively attached to the bottom of the cap, and an elongate distribution tube selectively mounted to the cap. The reaction vessel is filled with a preselected amount of carbonating material such that when the control ring is rotated in one position, water may be introduced into the vessel to initiate the carbonation reaction. In another position, the carbonating gas flows into the liquid via the distribution tube. Other rotated positions permit locking and unlocking of the control ring. The carbonation device also includes a drop-in configuration that serves as a self-contained carbonation distribution vessel.

Abstract translation: 碳酸化装置包括选择性地安装到液体容器的口部的盖系统。 盖系统包括盖，与盖同轴并选择性地附接到盖的可旋转控制环，选择性地附接到盖的底部的反应容器和选择性地安装到盖的细长分配管。 反应容器填充有预选量的碳酸化材料，使得当控制环在一个位置旋转时，可以将水引入容器中以引发碳酸化反应。 在另一位置，碳酸化气体经由分配管流入液体。 其他旋转位置允许控制环的锁定和解锁。 碳酸化装置还包括用作独立碳酸化分配容器的滴入构造。

公开(公告)号：US20110112543A1

公开(公告)日：2011-05-12

申请号：US12675455

申请日：2008-08-28

Applicant: Robert Palazzolo ,  Manish Sutaria ,  Aliassghar N. Tofighi ,  Tak L. Chang ,  Aron D. Rosenberg

Inventor： Robert Palazzolo ,  Manish Sutaria ,  Aliassghar N. Tofighi ,  Tak L. Chang ,  Aron D. Rosenberg

IPC: A61B17/58

CPC classification number: B01F15/0201 ,  A61B17/8827 ,  B01F5/0685 ,  B01F5/0688 ,  B01F11/0071 ,  B01F15/0225

Abstract: Bone cement mixing and delivery device and methods are disclosed. The device includes a first tube/barrel (e.g., a syringe barrel) containing a bone cement powder and a second tube/barrel that can be filled with or that contains a liquid; the first and second tubes/barrels can be fluidly connected end-to-end such that there is fluid communication between the tubes/barrels. Also disclosed are methods of preparing the device for use, methods for forming a bone cement using the device, and methods and device design to extend the shelf life of the device.

Abstract translation: 公开了骨水泥混合输送装置和方法。 该装置包括含有骨水泥粉末的第一管/桶（例如，注射器筒）和可填充或含有液体的第二管/桶; 第一和第二管/桶可以端对端流体连接，使得管/桶之间存在流体连通。 还公开了制备使用装置的方法，使用该装置形成骨水泥的方法以及延长装置的保质期的方法和装置设计。

公开(公告)号：US20110097788A1

公开(公告)日：2011-04-28

申请号：US12915911

申请日：2010-10-29

Applicant: David FARROW

Inventor： David FARROW

IPC: C12M1/34

CPC classification number: B82Y30/00 ,  B01D61/18 ,  B01F3/20 ,  B01F3/2057 ,  B01F5/0646 ,  B01F5/0647 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0237 ,  B01F2215/0431 ,  B01F2215/045 ,  B01L3/502753 ,  B01L2200/10 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/0883 ,  B01L2300/0896 ,  B01L2400/0478 ,  B01L2400/0481 ,  C12Q1/703 ,  G01N1/405 ,  G01N15/1031 ,  G01N33/56988 ,  C12Q2565/501

Abstract: The invention relates to methods and devices for detecting the presence of a particle of interest (hereinafter an analyte particle) in a fluid. A detection device exemplary of the present invention filters a sample of the fluid to remove particles larger than the analyte particles. A reagent solution, containing reagent particles smaller than the analyte particles, is then added to the sample. The reagent particles will react with the analyte particles, if any are present, to form reagent-analyte complexes which are larger than the analyte particles. The sample is then filtered a second time to remove particles the same size as or smaller than the analyte particles. The sample is then tested for the presence of reagent-analyte complexes to detect the presence of the analyte particle in the fluid.

Abstract translation: 本发明涉及用于检测流体中感兴趣的颗粒（以下称为分析物颗粒）的存在的方法和装置。 本发明示例性的检测装置对流体样品进行过滤以除去大于分析物颗粒的颗粒。 然后将含有小于分析物颗粒的试剂颗粒的试剂溶液加入到样品中。 试剂颗粒将与分析物颗粒（如果有的话）反应，形成大于分析物颗粒的试剂 - 分析物复合物。 然后将样品第二次过滤以除去与分析物颗粒相同的尺寸或更小的颗粒。 然后对样品进行试剂 - 分析物复合物的存在，以检测流体中分析物颗粒的存在。

公开(公告)号：US20110068124A1

公开(公告)日：2011-03-24

申请号：US12737013

申请日：2009-06-10

Applicant: David L. Reynolds ,  Daniel Macdonald ,  Roger McCarthy

Inventor： David L. Reynolds ,  Daniel Macdonald ,  Roger McCarthy

IPC: B67D7/06

CPC classification number: B01F15/0201 ,  A61M5/2448 ,  A61M2005/3152 ,  B01F13/002 ,  B01F13/0023 ,  B01F15/0087 ,  B01F15/0237

Abstract: A device for mixing a substance comprised of two constituents contained in a cartridge (12) and having a cartridge holder (32) thereabout, the device comprising a plunger rod (46) for pushing a closure member (20) to permit the transfer of a diluent in a second chamber (28) through a by-pass channel (24) to mix with a constituent in a first chamber (26), the plunger rod (48) being driven by means of a rack (48) and a pinion gear (50) arrangement to prevent overly rapid movement of the plunger rod (46).

Abstract translation: 一种用于混合包含在盒（12）中的两个组分并且在其周围具有盒保持器（32）的物质的装置，该装置包括用于推动封闭构件（20）以允许传送一个 稀释剂通过旁通通道（24）在第二腔室（28）中与第一腔室（26）中的组分混合，柱塞杆（48）通过齿条（48）和小齿轮 （50）布置以防止柱塞杆（46）的过度快速移动。