公开(公告)号：US08644663B2

公开(公告)日：2014-02-04

申请号：US12987736

申请日：2011-01-10

Applicant: Bertrand Viellerobe ,  Francois Lacombe ,  Nicolas Boularot ,  Francois Doussoux ,  Nicolas Lavillonniere

Inventor： Bertrand Viellerobe ,  Francois Lacombe ,  Nicolas Boularot ,  Francois Doussoux ,  Nicolas Lavillonniere

IPC: G02B6/06

CPC classification number: G01N21/6458 ,  A61B1/00117 ,  A61B1/00165 ,  A61B1/00172 ,  A61B1/043 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/07 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0084 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2201/024 ,  G01N2201/0846 ,  G01N2201/086 ,  G02B6/29362 ,  G02B21/16

Abstract: An imaging device including an illumination module including at least one emitter for emitting at least one excitation beam, a scanning and injection module including an image guide, a proximal end and a distal end of which are linked by a plurality of optical fibers, and a scanning and injection optical system configured to alternately inject the at least one excitation beam into an optical fiber of the image guide from the proximal end of the image guide, and a detection module including at least one detector for detecting at least one luminous flux collected at the distal end of the image guide. At least one of the illumination module and the detection module is optically conjugated with the scanning and injection module by a conjugating optical fiber.

Abstract translation: 一种成像装置，包括包括至少一个用于发射至少一个激发光束的发射器的照明模块，包括图像引导件的扫描和注射模块，其近端和远端由多根光纤连接， 扫描和注射光学系统，被配置为将至少一个激发光束从图像引导件的近端交替地注入到图像引导件的光纤中，以及检测模块，包括至少一个检测器，用于检测在 图像引导件的远端。 照明模块和检测模块中的至少一个通过共轭光纤与扫描和注入模块光学共轭。

公开(公告)号：US20110141465A1

公开(公告)日：2011-06-16

申请号：US12991765

申请日：2009-05-20

Applicant: Anthony Jeannotte ,  Michael J. Leveille ,  Frank Denecke

Inventor： Anthony Jeannotte ,  Michael J. Leveille ,  Frank Denecke

IPC: G01N1/10

CPC classification number: G01N21/05 ,  G01N35/1095 ,  G01N2021/0346 ,  G01N2201/024 ,  G01N2201/08 ,  G01N2201/086

Abstract: A flow cell for a photometric device includes a module having a body with a distal face defining an annular channel. The body also defines an axial central passage and an axial flow channel. A second module has a body with a proximal face defining an annular channel. The second body also defines an axial flow channel in fluid communication with the first axial flow channel. A light guiding member is within the central passage for exposing a fluid in the flow channels of the modules. An assembly seals an interface between the distal and proximal faces such that the fluid does not leak from the flow channels. The assembly has a metal gasket between the distal and proximal faces, the metal gasket defining a flow path between the flow channels, a first sealing member in the first annular channel and a second sealing member in the second annular channel.

Abstract translation: 用于光度测量装置的流动池包括具有主体的模块，该主体具有限定环形通道的远端面。 主体还限定轴向中心通道和轴向流动通道。 第二模块具有主体，其具有限定环形通道的近端面。 第二主体还限定与第一轴向流动通道流体连通的轴向流动通道。 导光构件在中央通道内部，用于暴露模块的流动通道中的流体。 组件密封远端和近端面之间的界面，使得流体不会从流动通道泄漏。 该组件在远端和近端面之间具有金属垫圈，金属垫圈限定了流动通道之间的流动路径，第一环形通道中的第一密封构件和第二环形通道中的第二密封构件。

公开(公告)号：US20040090622A1

公开(公告)日：2004-05-13

申请号：US10476425

申请日：2003-10-30

Inventor： Hans Ole Nielsen ,  Jan H. Hansen ,  Kim P. Hansen

IPC: G01N021/64

CPC classification number: G01N21/6408 ,  G01N21/7703 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6434 ,  G01N2021/6484 ,  G01N2201/086

Abstract: An apparatus and devices for measuring fluorescence lifetimes of fluorescence sensors for one or more analytes, the apparatus comprising (c) one or more reference systems (3,6,7), said reference systems each comprising one or more reference light sources (3) and being adapted to receive one or more excitation signals (1a), to produce reference optical signals (6b) in response thereto, and to produce one or more electrical reference output signals (7b) in response to one or more excitation signals (1a); and (d) or more phase detectors (10), said phase detections being adapted to detect one or more delays of said one or more electrical output signals of said one or more fluorescence sensor systems and said one or more reference systems, and to produce one or more phase output signals; and a method of measuring concentration of one or more analytes using such apparatus and/or devices.

Abstract translation: 一种用于测量一种或多种分析物的荧光传感器的荧光寿命的装置和装置，所述装置包括（c）一个或多个参考系统（3,6,7），所述参考系统各自包括一个或多个参考光源（3） 并且适于接收一个或多个激励信号（1a）以响应于此产生参考光信号（6b），并且响应于一个或多个激励信号（1a）产生一个或多个电参考输出信号（7b） ; 和（d）或更多相位检测器（10），所述相位检测器适于检测所述一个或多个荧光传感器系统和所述一个或多个参考系统的所述一个或多个电输出信号的一个或多个延迟，并且产生 一个或多个相位输出信号; 以及使用这种装置和/或装置测量一种或多种分析物的浓度的方法。