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31.发明申请METHOD FOR FABRICATING 3D STRUCTURE HAVING HYDROPHOBIC SURFACE BY DIPPING METHOD 有权通过DIPPING方法制作具有疏水性表面的3D结构的方法公开(公告)号：US20110042350A1
公开(公告)日：2011-02-24
申请号：US12921217
申请日：2009-03-12
Applicant: Dong-Seob Kim , Kun-Hong Lee , Woon-Bong Hwang , Geun-Bae Lim , Hyun-Chul Park , Byeong-Joo Lee , Sang-Min Lee , Joon-Won Kim
Inventor： Dong-Seob Kim , Kun-Hong Lee , Woon-Bong Hwang , Geun-Bae Lim , Hyun-Chul Park , Byeong-Joo Lee , Sang-Min Lee , Joon-Won Kim
CPC classification number: C23C2/12 , B29C33/424 , B29C39/34 , C23C2/26 , C25D11/04
Abstract: A method for fabricating a 3D (three-dimensional) structure is disclosed to provide hydrophobicity to a surface of a 3D structure by using a dipping method in which a predetermined-shaped structure is immersed in a molten metal solution. The method includes: immersing a predetermined-shaped structure in a molten metal solution to coat a molten metal material on the surface of the predetermined-shaped structure; anodizing a metal base coated with the molten metal material; coating a polymer material on an outer surface of the metal-coated base to form a negative replica structure; covering an outer surface of the negative replica structure with an outer formation material; and removing the metal-coated base from the negative replica structure and the outer formation material.
Abstract translation: 公开了一种用于制造3D（三维）结构的方法，通过使用将预定形状的结构浸入熔融金属溶液中的浸渍方法来提供对3D结构的表面的疏水性。 该方法包括：将预定形状的结构浸入熔融金属溶液中以在预定形状的结构的表面上涂覆熔融金属材料; 阳极氧化涂有熔融金属材料的金属基底; 在金属涂覆的基底的外表面上涂覆聚合物材料以形成负的复制结构; 用外部形成材料覆盖负重复结构的外表面; 以及从阴性复制结构和外部形成材料中去除金属涂覆的基底。
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32.发明申请METHOD FOR FABRICATING 3D STRUCTURE HAVING HYDROPHOBIC SURFACE USING METAL FOIL 有权使用金属箔制造具有疏水性表面的三维结构的方法公开(公告)号：US20110012285A1
公开(公告)日：2011-01-20
申请号：US12921585
申请日：2009-03-12
Applicant: Dong-Seob Kim , Kun-Hong Lee , Woon-Bong Hwang , Geun-Bae Lim , Hyun-Chul Park , Byeong-Joo Lee , Sang-Min Lee , Joon-Won Kim
Inventor： Dong-Seob Kim , Kun-Hong Lee , Woon-Bong Hwang , Geun-Bae Lim , Hyun-Chul Park , Byeong-Joo Lee , Sang-Min Lee , Joon-Won Kim
IPC: B29C39/12
CPC classification number: B29C39/12 , B29C33/424 , B29C33/485 , B29C39/34 , B29L2031/756 , C25D11/045 , C25D11/16 , C25D11/24
Abstract: A method for fabricating a 3D (three-dimensional) structure such that the 3D structure has a surface with hydrophobicity by using a metal foil such as an aluminum foil is disclosed. The method includes preparing a metal foil base by attaching a metal foil on an outer surface of a predetermined-shaped 3D structure; anodizing the metal foil base; coating a polymer material on the outer surface of the metal foil base material to form a negative replica structure; forming an outer structure by covering an outer surface of the negative replica structure with an outer formation material; and removing the metal foil base.
Abstract translation: 公开了一种用于制造3D（三维）结构的方法，使得3D结构具有通过使用诸如铝箔的金属箔具有疏水性的表面。 该方法包括通过在预定形状的3D结构的外表面上附着金属箔来制备金属箔基底; 阳极氧化金属箔基底; 在金属箔基材的外表面上涂覆聚合物材料以形成负的复制结构; 通过用外部形成材料覆盖所述负面复制结构的外表面来形成外部结构; 并移除金属箔基底。
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33.发明授权Molecular detection methods using molecular detection chips including a metal oxide semiconductor field effect transistor 有权使用包括金属氧化物半导体场效应晶体管的分子检测芯片的分子检测方法公开(公告)号：US07781167B2
公开(公告)日：2010-08-24
申请号：US11756083
申请日：2007-05-31
Applicant: Geun-Bae Lim , Chin-Sung Park , Yoon-Kyoung Cho , Sun-Hee Kim
Inventor： Geun-Bae Lim , Chin-Sung Park , Yoon-Kyoung Cho , Sun-Hee Kim
CPC classification number: G01N33/5438 , B01J2219/00497 , B01J2219/00511 , B01J2219/00585 , B01J2219/00596 , B01J2219/00653 , B01J2219/00657 , B01J2219/00659 , B01J2219/00677 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , B01J2219/00731 , B01J2219/00743 , B01L3/5027 , B82Y15/00 , B82Y30/00 , C12Q1/6837 , G01N27/4145 , G01N33/54373 , C12Q2565/607
Abstract: A molecular detection chip including a metal oxide silicon-field effect transistor (MOSFET) on sidewalls of a micro-fluid channel and a molecular detection device including the molecular detection chip are provided. A molecular detection method, particularly, qualification methods for the immobilization of molecular probes and the binding of a target sample to the molecular probes, using the molecular detection device, and a nucleic acid mutation assay device and method are also provided. The formation of the MOSFET on the sidewalls of the micro-fluid channel makes easier to highly integrate a molecular detection chip. In addition, immobilization of probes directly on the surface of a gate electrode ensures the molecular detection chip to check for the immobilization of probes and coupling of a target molecule to the probes in situ.
Abstract translation: 提供了包括在微流体通道的侧壁上的金属氧化物硅场效应晶体管（MOSFET）和包括分子检测芯片的分子检测装置的分子检测芯片。 还提供了使用分子检测装置的分子检测方法，特别是用于固定分子探针的鉴定方法和靶样品与分子探针的结合，以及核酸突变测定装置和方法。 在微流体通道的侧壁上形成MOSFET更容易高度集成分子检测芯片。 此外，探针直接固定在栅电极的表面上确保了分子检测芯片，以检查探针的固定和目标分子与探针原位偶联。
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34.发明授权公开(公告)号：US07442503B2
公开(公告)日：2008-10-28
申请号：US10765366
申请日：2004-01-27
Applicant: Sun-hee Kim , Soo-suk Lee , Geun-bae Lim , Young-sun Lee
Inventor： Sun-hee Kim , Soo-suk Lee , Geun-bae Lim , Young-sun Lee
CPC classification number: B01L3/508 , B01L7/52 , B01L2300/163 , B05D1/62 , B05D2203/35 , C03C17/30
Abstract: Provided is a method of treating a surface of a substrate used in a biochemical reaction system, the method including forming a polymer film on the surface by vapor deposition of a compound of formula (1) below and a compound of formula (2) below: (RO)3—Si—(CH2)n1—X (1) (RO)3—Si—(CH2)n2—(CF2)m—X (2) wherein R is one of a methyl group and an ethyl group, X is one of a methyl group and a trifluoromethyl group, n1 is an integer from 1 to 3, n2 is an integer from 1 to 10, and m is an integer from 1 to 10.
Abstract translation: 本发明提供一种处理生物化学反应体系中使用的基板的表面的方法，该方法包括通过以下式（1）的化合物和下述式（2）的化合物的气相沉积在表面上形成聚合物膜： （？）（？）（？）？（？）？（？）？（？）？ n1 -X（1）<？in-line-formula description =“In-line Formulas”end =“tail”？> <？in-line-formula description =“In-line Formulas”end =“ （RO）3 - （CH 2）2 - （CF 2）2 - （CH 2） 其中R是甲基和乙基之一，X是一个，其中R是甲基和乙基之一， 的甲基和三氟甲基，n1为1〜3的整数，n2为1〜10的整数，m为1〜10的整数。
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35.发明授权公开(公告)号：US07338808B2
公开(公告)日：2008-03-04
申请号：US10698507
申请日：2003-10-31
Applicant: Yoon-kyoung Cho , Sang-min Shin , In-seok Kang , Geun-bae Lim
Inventor： Yoon-kyoung Cho , Sang-min Shin , In-seok Kang , Geun-bae Lim
CPC classification number: B01F13/0076 , B01L3/50273 , B01L3/502769 , B01L2400/0418 , G01N27/44752 , Y10T436/11
Abstract: Provided is a method for determining a zeta potential generated between a solid wall and a solution. The method includes (a) injecting an electrolyte solution into a first inlet of a T channel, which is provided with first and second inlet electrodes and a grounded outlet electrode, and a mixed solution of the electrolyte solution and a fluorescent dye into a second channel of the T channel and maintaining a steady-state of the two solutions; (b) applying a direct current electric field from the first and second electrodes to the outlet electrode to form an interface between the electrolyte solution and the mixed solution; (c) applying an alternating current electric field from one of the two inlet electrodes to the outlet electrode to oscillate the interface; and (d) measuring an amplitude of oscillation of the interface and determining the zeta potential from the standard relationship between the zeta potential and the amplitude.
Abstract translation: 提供了一种确定固体壁和溶液之间产生的ζ电位的方法。 该方法包括：（a）将电解质溶液注入T沟道的第一入口，T通道的第一入口设置有第一入口电极和第二入口电极和接地的出口电极，以及电解质溶液和荧光染料的混合溶液到第二通道 的T通道，并保持两种解决方案的稳定状态; （b）将直流电场从第一和第二电极施加到出口电极以形成电解质溶液和混合溶液之间的界面; （c）将两个入口电极之一的交流电场施加到出口电极以使界面振荡; 和（d）测量界面的振荡幅度，并根据ζ电位和幅度之间的标准关系确定ζ电位。
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Patent Agency Ranking
36.发明授权Electrically conductive polymer, sensor using the same, and method for detecting target molecule using the sensor 有权导电聚合物，使用其的传感器以及使用传感器检测靶分子的方法公开(公告)号：US06987164B2
公开(公告)日：2006-01-17
申请号：US10383809
申请日：2003-03-06
Applicant: Jun-hoe Cha , Young Choi , Jung-im Han , Geun-bae Lim
Inventor： Jun-hoe Cha , Young Choi , Jung-im Han , Geun-bae Lim
IPC: E08G75/00
CPC classification number: G01N33/545 , C08G61/126 , G01N33/5438 , H01B1/127
Abstract: A novel electrically conductive polymer, a sensor using the electrically conductive polymer, and a method for detecting a target molecule that hybridizes to a probe, using the sensor, are provided. The electrically conductive polymer has the following formula: where m is 1, 2, or 3; R is a hydroxysuccinimidyl group, a hydroxyphthalimidyl group, or a pentafluorophenolyl group; and n is zero or an integer.
Abstract translation: 提供了一种新型导电聚合物，使用导电聚合物的传感器，以及使用传感器检测与探针杂交的靶分子的方法。 导电聚合物具有下式：其中m为1,2或3; R是羟基琥珀酰亚胺基，羟基邻苯二甲酰亚氨基或五氟苯基; 并且n为零或整数。
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公开(公告)号：US08481261B2
公开(公告)日：2013-07-09
申请号：US13001444
申请日：2009-06-22
Applicant: Geun-Bae Lim , Ji-Min Kahng , Tae-Hee Kang , Jin-Hwa Jung
Inventor： Geun-Bae Lim , Ji-Min Kahng , Tae-Hee Kang , Jin-Hwa Jung
CPC classification number: C12N15/1017 , C12N15/1006
Abstract: The present invention relates to a nucleic acid extracting apparatus, and the nucleic acid extracting apparatus can include a pipe-shaped tube having an open outlet at one side thereof, and a hydrogel column that is provided inside the tube and filters impurities excluding an extraction target material.
Abstract translation: 核酸提取装置技术领域本发明涉及核酸提取装置，核酸提取装置可以包括在其一侧具有开放出口的管状管和设置在管内的水凝胶柱，并且除去除去提取目标之外的杂质 材料。
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公开(公告)号：US07854853B2
公开(公告)日：2010-12-21
申请号：US11595077
申请日：2006-11-09
Applicant: Pan-Kyeom Kim , Geun-Bae Lim
Inventor： Pan-Kyeom Kim , Geun-Bae Lim
IPC: B44C1/22
CPC classification number: C03C17/06 , C03C15/00 , C03C21/008 , C03C23/007
Abstract: An exemplary embodiment of the present invention provides a nano fabrication method for a glass, the method including forming a molecule substituting layer on a glass substrate, patterning the molecule substituting layer correspondent to shapes to be patterned on the glass substrate, substituting crystal atoms of the glass substrate with atoms of the molecule substituting layer, removing the patterned molecule substituting layer from the glass substrate, and etching the molecule substituted portion of the glass substrate.
Abstract translation: 本发明的一个示例性实施例提供了一种用于玻璃的纳米制造方法，该方法包括在玻璃基板上形成分子取代层，将与图案化形状对应的分子取代层图案化在玻璃基板上， 玻璃基板，分子取代层的原子，从玻璃基板除去图案化分子取代层，并蚀刻玻璃基板的分子取代部分。
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公开(公告)号：US20080110863A1
公开(公告)日：2008-05-15
申请号：US11595077
申请日：2006-11-09
Applicant: Pan-Kyeom Kim , Geun-Bae Lim
Inventor： Pan-Kyeom Kim , Geun-Bae Lim
IPC: B44C1/22
CPC classification number: C03C17/06 , C03C15/00 , C03C21/008 , C03C23/007
Abstract: An exemplary embodiment of the present invention provides a nano fabrication method for a glass, the method including forming a molecule substituting layer on a glass substrate, patterning the molecule substituting layer correspondent to shapes to be patterned on the glass substrate, substituting crystal atoms of the glass substrate with atoms of the molecule substituting layer, removing the patterned molecule substituting layer from the glass substrate, and etching the molecule substituted portion of the glass substrate.
Abstract translation: 本发明的一个示例性实施例提供了一种用于玻璃的纳米制造方法，该方法包括在玻璃基板上形成分子取代层，将与图案化形状对应的分子取代层图案化在玻璃基板上， 玻璃基板与分子取代层的原子，从玻璃基板去除图案化的分子取代层，并蚀刻玻璃基板的分子取代部分。
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40.发明授权Electrically conductive polymer, sensor using the same, and method for detecting target molecule using the sensor 失效导电聚合物，使用其的传感器以及使用传感器检测靶分子的方法公开(公告)号：US07341759B2
公开(公告)日：2008-03-11
申请号：US11134984
申请日：2005-05-23
Applicant: Jun-hoe Cha , Young Choi , Jung-im Han , Geun-bae Lim
Inventor： Jun-hoe Cha , Young Choi , Jung-im Han , Geun-bae Lim
CPC classification number: G01N33/545 , C08G61/126 , G01N33/5438 , H01B1/127
Abstract: A novel electrically conductive polymer, a sensor using the electrically conductive polymer, and a method for detecting a target molecule that hybridizes to a probe, using the sensor, are provided. The electrically conductive polymer has the following formula: where m is 1, 2, or 3; R is a hydroxysuccinimidyl group, a hydroxyphthalimidyl group, or a pentafluorophenolyl group; and n is zero or an integer.
Abstract translation: 提供了一种新型导电聚合物，使用导电聚合物的传感器，以及使用传感器检测与探针杂交的靶分子的方法。 导电聚合物具有下式：其中m为1,2或3; R是羟基琥珀酰亚胺基，羟基邻苯二甲酰亚氨基或五氟苯基; 并且n为零或整数。
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