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公开(公告)号:US20220177948A1
公开(公告)日:2022-06-09
申请号:US17299018
申请日:2019-12-03
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor: Yasushi OKADA , Tetsuro ARIYOSHI
IPC: C12Q1/6806 , C12Q1/6825 , C12Q1/6876
Abstract: The present invention provides a fluorogenic RNA capable of visualizing mRNA in cells, particularly, living mammalian cells, and a target RNA fluorescent labeling method using the fluorogenic RNA. The present invention provides a fluorogenic nucleic acid molecule containing a base sequence having two or more fluorescent molecule-binding regions linked via a linker sequence, in which one or more fluorescent molecule-binding aptamer sequences are inserted into a scaffold sequence of each of the fluorescent molecule-binding regions.
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公开(公告)号:US11352652B2
公开(公告)日:2022-06-07
申请号:US16976222
申请日:2019-03-04
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor: Naoki Takaya , Shunsuke Masuo , Yukie Kawasaki , Hajime Minakawa
IPC: C12P13/00
Abstract: Provided is a novel method for producing 4-aminocinnamic acid from 4-nitrophenylalanine. This method comprises: converting 4-nitrophenylalanine into 4-nitrocinnamic acid; and converting 4-nitrocinnamic acid into 4-aminocinnamic acid.
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公开(公告)号:US11320639B2
公开(公告)日:2022-05-03
申请号:US15920824
申请日:2018-03-14
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor: Masanori Matsuzaki , Shin-Ichiro Terada
Abstract: Describes herein are a microscope optical module, a microscope, a control device for the microscope optical module, and multiphoton excitation microscope, which can switch the observation field of view at high speed and observe a large field of view. The microscope optical module includes an optical-axis-shifting optical system having an optical element, an optical-axis-shifting optical system support for positioning the optical-axis-shifting optical system with respect to the objective light flux of the microscope, and a rotator arranged on the optical-axis-shifting optical system support, the rotator rotatably supporting the optical-axis-shifting optical system with respect to the optical axis of the objective light flux, wherein the microscope optical module is added to an objective light flux side of a microscope.
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公开(公告)号:US20220102656A1
公开(公告)日:2022-03-31
申请号:US17422550
申请日:2020-01-30
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor: Ayumi NIHEI , Tsutomu MIYASAKA
Abstract: A photoelectric conversion element includes a first layer, a second layer, and a third layer that are laminated in this order. The first layer is formed of a plurality of particles including an inorganic semiconductor as a main component, an aggregate of the particles, or a thin film including an inorganic semiconductor as a main component. The second layer is provided on a surface of each of the particles or the aggregate and is formed of a plurality of particles including a perovskite structure as a main component, an aggregate of the particles, or a thin film including a perovskite structure as a main component. The third layer is formed of a plurality of particles including an organic metal complex as a main component, an aggregate of the particles, or a thin film including an organic metal complex as a main component.
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公开(公告)号:US20220016344A1
公开(公告)日:2022-01-20
申请号:US17382853
申请日:2021-07-22
Applicant: Japan Science and Technology Agency
Inventor: Toshiaki OHARA , Hiroshi SUITO , Yoshiki SUGITANI
Abstract: The drug administration quantitative management assisting system includes an inputter and a calculator. The inputter receives, as input data, a time passed from previous drug administration to a patient and/or a value of biological materials in blood of the patient and/or a change of the value. The calculator calculates probabilities of drug administration to the patient as trinary determination of the dosage direction of STAY, UP or DOWN on the basis of a calculation model, and a first determination for determining the dosage direction, and a second determination for determining the dosage direction of UP or DOWN if the first determination is NON-STAY. The calculation model is prepared by machine learning using, as training data, the time passed from previous drug administration to a plurality of patients and/or the value of the biological material in blood of the plurality of patients and/or the changes of the value, and data indicating, as previous determination of the drug administration to the plurality of patients determined by doctors, any one of the dosage directions.
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公开(公告)号:US20210246041A1
公开(公告)日:2021-08-12
申请号:US17053436
申请日:2019-05-07
Applicant: Japan Science and Technology Agency
Inventor: Katsutoshi Nagaoka , Yuta Ogura , Katsutoshi Sato
IPC: C01C1/04 , B01J23/63 , B01J23/10 , B01J23/83 , B01J23/00 , B01J23/58 , B01J21/10 , B01J37/02 , B01J37/08 , B01J37/18 , B01J37/00 , C01F17/241 , C01F17/32 , B01J37/04 , B01J35/02
Abstract: A composite oxide including a metal element represented by the composition of general formula: AnXy, represents an element selected from the group consisting of Sc, Y, and a trivalent lanthanoid; X represents an element selected from the group consisting of Ca, Sr, and Ba; n is 0
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公开(公告)号:US11059014B2
公开(公告)日:2021-07-13
申请号:US15752986
申请日:2016-08-12
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY , AYABO CORPORATION
Inventor: Atsushi Nakajima , Hironori Tsunoyama , Hiroki Akatsuka , Keizo Tsukamoto
Abstract: The present invention relates to a nanocluster liquid dispersion where nanoclusters with a predetermined number of atoms are dispersed.
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公开(公告)号:US20210119165A1
公开(公告)日:2021-04-22
申请号:US17135694
申请日:2020-12-28
Applicant: Japan Science and Technology Agency
Inventor: Jun-Ichi Hanna , Keiji Tokunaga , Hiroaki Iino
Abstract: An organic material having at least one aromatic conjugated π-electron system is selected. The purity of the organic material is improved by purification, and a conduction mechanism of the organic material is confirmed by a time-of-flight method, whereby a liquid phase of the organic material is usable as an organic semiconductor. A method that enables the usage of a liquid phase of an organic material as an organic semiconductor is provided. The method involves confirming the electronic conduction of the organic material having at least one aromatic conjugated π-electron system by evaluation of a charge transport property using a time-of-flight method, and by evaluation of a dilution effect caused by addition of a diluent.
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公开(公告)号:US20210057758A1
公开(公告)日:2021-02-25
申请号:US16978306
申请日:2019-03-05
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor: Miho YAMAUCHI , Tatsuyoshi MORIMOTO
Abstract: This electrode catalyst of the present invention contains an electrically conductive material that supports a metal or a metal oxide, wherein electrical conductivity at 30° C. is 1×10−13 Scm−1 or greater.
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公开(公告)号:US20210002142A1
公开(公告)日:2021-01-07
申请号:US16980166
申请日:2019-03-13
Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
Inventor: Yoji KOBAYASHI , Hiroshi KAGEYAMA , Hiroki YAMASHITA , Thibault BROUX
IPC: C01F17/224 , B01J23/63 , C01C1/04
Abstract: The present invention is to provide an electron or hydride ion intake/release material comprising a lanthanoid oxyhydride represented by the formula Ln(HO) (in the formula, Ln represents a lanthanoid element) or an electron or hydride ion intake/release composition comprising at least one kind of lanthanoid oxyhydride; a transition metal-supported material wherein a transition metal is supported by the above electron or hydride ion intake/release material or electron or hydride ion intake/release composition; and a catalyst comprising the transition metal-supported material. The electron or hydride ion intake/release material or electron or hydride ion intake/release composition according to the present invention has a higher ability for intake/release of electron or hydride ion than that of a conventional hydride-containing compound, and can be used effectively as a catalyst such as a catalyst having excellent ammonia synthesis activity by supporting a transition metal thereon.
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