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    METHOD AND APPARATUS FOR IMMOBILIZING TARGET MATERIAL ON SUBSTRATE
    31.
    发明申请
    METHOD AND APPARATUS FOR IMMOBILIZING TARGET MATERIAL ON SUBSTRATE 审中-公开
    用于固定靶材的靶材的方法和装置

    公开(公告)号：US20110046019A1

    公开(公告)日：2011-02-24

    申请号：US12702381

    申请日：2010-02-09

    Applicant: Su-hyeon KIM

    Inventor： Su-hyeon KIM

    IPC: C40B50/18 ,  C40B60/14

    CPC classification number: G01N33/54353

    Abstract: A method for immobilizing a target material on a substrate includes applying a voltage across a first solution including the target material in contact with a surface of a film including a pore disposed therein, a second solution in contact with an opposite surface of the film, and a substrate disposed facing the opposite surface of the film, moving the target material from the first solution, through the pore of the film into the second solution, and immobilizing the target material on the substrate.

    Abstract translation: 将目标材料固定在基板上的方法包括在包括目标材料的第一溶液上施加电压，所述第一溶液与包括设置在其中的孔的膜的表面接触，与膜的相对表面接触的第二溶液，以及 面向所述膜的相对表面的基板，将所述目标材料从所述第一溶液移动通过所述膜的孔进入所述第二溶液，并将所述靶材固定在所述基板上。

    METHOD OF REDUCING TEMPERATURE DIFFERENCE BETWEEN A PAIR OF SUBSTRATES AND FLUID REACTION DEVICE USING THE SAME
    32.
    发明申请
    METHOD OF REDUCING TEMPERATURE DIFFERENCE BETWEEN A PAIR OF SUBSTRATES AND FLUID REACTION DEVICE USING THE SAME 失效
    降低基板对流与使用其的流体反应装置之间的温度差异的方法

    公开(公告)号：US20110033919A1

    公开(公告)日：2011-02-10

    申请号：US12904557

    申请日：2010-10-14

    Applicant: Kak NAMKOONG ,  Su-hyeon KIM ,  Jin-tae KIM ,  Chin-sung PARK ,  Young-sun LEE

    Inventor： Kak NAMKOONG ,  Su-hyeon KIM ,  Jin-tae KIM ,  Chin-sung PARK ,  Young-sun LEE

    IPC: C12M1/40

    CPC classification number: B81B3/0081 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00873 ,  B01L3/5027 ,  B01L7/5255 ,  B01L2200/14 ,  B01L2200/147 ,  B01L2300/1805 ,  B01L2300/1827 ,  B81B2201/051 ,  F28F21/02 ,  F28F2013/006

    Abstract: A method of reducing a temperature difference between a high-temperature and a low-temperature substrate includes interposing a heat transfer facilitating layer which has a higher thermal conductivity than air and can hold particles between the substrates, and maintaining close contact between the high-temperature substrate, the heat transfer facilitating layer, and the low-temperature substrate, wherein formation of an air layer can be at least substantially prevented between the high-temperature substrate and the heat transfer facilitating layer, and between the low-temperature substrate and the heat transfer facilitating layer. A fluid reaction device includes a microfluidic reaction chip which accommodates a fluid, a heater, and a heat transfer facilitating layer which is interposed between the microfluidic reaction chip and the heater, the heat transfer facilitating layer has a higher thermal conductivity than air and can hold particles, wherein formation of an air layer can be prevented.

    Abstract translation: 降低高温和低温基板之间的温度差的方法包括：介于热传导率高于空气的传热促进层，并且可以在基板之间保持颗粒，并且保持高温 基板，传热促进层和低温基板，其中至少可以在高温基板和传热促进层之间以及在低温基板和热量之间基本上防止空气层的形成 转移促进层。 流体反应装置包括容纳流体的微流体反应芯片，加热器和介于微流体反应芯片和加热器之间的传热促进层，传热促进层具有比空气更高的导热性并且可以保持 颗粒，其中可以防止空气层的形成。

    METHOD OF REDUCING TEMPERATURE DIFFERENCE BETWEEN A PAIR OF SUBSTRATES AND FLUID REACTION DEVICE USING THE SAME
    34.
    发明申请
    METHOD OF REDUCING TEMPERATURE DIFFERENCE BETWEEN A PAIR OF SUBSTRATES AND FLUID REACTION DEVICE USING THE SAME 有权
    降低基板对流与使用其的流体反应装置之间的温度差异的方法

    公开(公告)号：US20080053647A1

    公开(公告)日：2008-03-06

    申请号：US11689640

    申请日：2007-03-22

    Applicant: Kak Namkoong ,  Su-hyeon Kim ,  Jin-tae Kim ,  Chin-sung Park ,  Young-sun Lee

    Inventor： Kak Namkoong ,  Su-hyeon Kim ,  Jin-tae Kim ,  Chin-sung Park ,  Young-sun Lee

    IPC: F28F7/00

    CPC classification number: B81B3/0081 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00873 ,  B01L3/5027 ,  B01L7/5255 ,  B01L2200/14 ,  B01L2200/147 ,  B01L2300/1805 ,  B01L2300/1827 ,  B81B2201/051 ,  F28F21/02 ,  F28F2013/006

    Abstract: A method of reducing a temperature difference between a high-temperature and a low-temperature substrate includes interposing a heat transfer facilitating layer which has a higher thermal conductivity than air and can hold particles between the substrates, and maintaining close contact between the high-temperature substrate, the heat transfer facilitating layer, and the low-temperature substrate, wherein formation of an air layer can be at least substantially prevented between the high-temperature substrate and the heat transfer facilitating layer, and between the low-temperature substrate and the heat transfer facilitating layer. A fluid reaction device includes a microfluidic reaction chip which accommodates a fluid, a heater, and a heat transfer facilitating layer which is interposed between the microfluidic reaction chip and the heater, the heat transfer facilitating layer has a higher thermal conductivity than air and can hold particles, wherein formation of an air layer can be prevented.

    Abstract translation: 降低高温和低温基板之间的温度差的方法包括：介于热传导率高于空气的传热促进层，并且可以在基板之间保持颗粒，并且保持高温 基板，传热促进层和低温基板，其中至少可以在高温基板和传热促进层之间以及在低温基板和热量之间基本上防止空气层的形成 转移促进层。 流体反应装置包括容纳流体的微流体反应芯片，加热器和介于微流体反应芯片和加热器之间的传热促进层，传热促进层具有比空气更高的导热性并且可以保持 颗粒，其中可以防止空气层的形成。

    Method of separating biomolecules using nanopore
    35.
    发明申请
    Method of separating biomolecules using nanopore 审中-公开
    使用纳米孔分离生物分子的方法

    公开(公告)号：US20060183112A1

    公开(公告)日：2006-08-17

    申请号：US11335246

    申请日：2006-01-19

    Applicant: Jun-hong Min ,  Su-hyeon Kim ,  In-ho Lee ,  Kui-hyun Kim ,  Seung-yeon Yang

    Inventor： Jun-hong Min ,  Su-hyeon Kim ,  In-ho Lee ,  Kui-hyun Kim ,  Seung-yeon Yang

    IPC: C12Q1/70 ,  C12Q1/68

    CPC classification number: G01N33/5438 ,  G01N33/48721

    Abstract: Provided is a method of separating particles, the method comprising: forming a first chamber and a second chamber separated by an interface with a pore, wherein the first and second chambers have electrodes with different polarities; placing particles to which a target biomolecule is bound from particles to which the target biomolecule is not bound in the first chamber; applying a voltage which has the same polarity as that of the target biomolecule to the electrode of the first chamber, and a voltage which has an opposite charge to that of the target biomolecule to the electrode of the second chamber; and translocating only the particles to which the target biomolecule is bound from the first chamber to the second chamber through the pore. Conventionally, the size of a pore is used to separate biomolecules. However, effective separation is difficult to achieve because the manufacture of a pore with a diameter of less than 10 nm, small enough to separate biomolecule, is not easy. Therefore, signal separation and data analysis must be required. However, in the present method, physical movement induced by the charge of biomolecules is used to effectively separate the biomolecules, thus obtaining a high signal to noise ratio. As a result, additional data analysis is not required.

    Abstract translation: 提供了一种分离颗粒的方法，该方法包括：形成由与孔的界面分隔开的第一室和第二室，其中第一和第二室具有不同极性的电极; 在第一室中放置靶生物分子所结合的颗粒与目标生物分子不结合的颗粒; 将具有与目标生物分子相同极性的电压施加到第一室的电极，以及将具有与靶生物分子相反的电荷的电压施加到第二室的电极; 并且仅将来自第一室的目标生物分子结合的颗粒通过孔转移到第二室。 通常，使用孔的大小来分离生物分子。 然而，由于直径小于10nm的孔的制造足够小以分离生物分子，所以难以实现有效的分离，这是不容易的。 因此，必须要求信号分离和数据分析。 然而，在本方法中，由生物分子的电荷引起的身体运动用于有效分离生物分子，从而获得高的信噪比。 因此，不需要额外的数据分析。

    Bio material receiving device and methods of manufacturing and operating the same
    36.
    发明授权
    Bio material receiving device and methods of manufacturing and operating the same 有权
    生物材料接收装置及其制造和操作方法

    公开(公告)号：US08664700B2

    公开(公告)日：2014-03-04

    申请号：US13096173

    申请日：2011-04-28

    Applicant: June-young Lee ,  Su-hyeon Kim

    Inventor： June-young Lee ,  Su-hyeon Kim

    IPC: G01N27/414

    CPC classification number: H01L51/0093 ,  B82Y10/00 ,  H01L27/28 ,  H01L27/281 ,  H01L51/0508

    Abstract: A bio material receiving device includes a thin film transistor (“TFT”) including a drain electrode, and a nano well accommodating a bio material. The drain electrode includes the nano well. The TFT may be a bottom gate TFT or a top gate TFT. A nano well array may include a plurality of bio material receiving devices. In a method of operating the bio material receiving device, each of the bio material receiving devices may be individually selected in the nano well array. When the bio material is accommodated in the selected bio material receiving device, a voltage is applied so that another bio material is not accommodated.

    Abstract translation: 生物材料接收装置包括包括漏电极的薄膜晶体管（“TFT”）和容纳生物材料的纳米孔。 漏电极包括纳米孔。 TFT可以是底栅极TFT或顶栅极TFT。 纳米孔阵列可以包括多个生物材料接收装置。 在生物材料接收装置的操作方法中，每个生物材料接收装置可以在纳米孔阵列中单独选择。 当生物材料容纳在所选择的生物材料接收装置中时，施加电压，使得不容纳另一生物材料。

    METHOD OF OPTIMIZING FLYING HEIGHT OF HEAD AND HARD DISK DRIVE MANUFACTURED BY THE SAME
    39.
    发明申请
    METHOD OF OPTIMIZING FLYING HEIGHT OF HEAD AND HARD DISK DRIVE MANUFACTURED BY THE SAME 审中-公开
    优化由其制造的头和硬盘驱动器的飞行高度的方法

    公开(公告)号：US20120075744A1

    公开(公告)日：2012-03-29

    申请号：US13233845

    申请日：2011-09-15

    Applicant: Seong Yong YOON ,  Myung Wook Song ,  Chang-Hwan Lee ,  Su-Hyeon Kim

    Inventor： Seong Yong YOON ,  Myung Wook Song ,  Chang-Hwan Lee ,  Su-Hyeon Kim

    IPC: G11B21/12

    CPC classification number: G11B5/6017

    Abstract: A hard disk drive includes a controller that optimizes a flying height of a head of a hard disk drive. The controller determines an optimal flying height of a head based on a preset table value and an MRR value of a head measured during a hard disk drive manufacturing process and sets the head according the determined optimal flying height such that recording capacitance is improved.

    Abstract translation: 硬盘驱动器包括一个优化硬盘驱动器头部飞行高度的控制器。 控制器基于预设表值和在硬盘驱动器制造过程中测量的磁头的MRR​​值来确定磁头的最佳飞行高度，并根据确定的最佳飞行高度设置磁头，使得记录电容得到改善。

    Device and method for rapidly lysing cells or viruses
    40.
    发明授权
    Device and method for rapidly lysing cells or viruses 失效
    用于快速裂解细胞或病毒的装置和方法

    公开(公告)号：US07531138B2

    公开(公告)日：2009-05-12

    申请号：US11560890

    申请日：2006-11-17

    Applicant: Su-hyeon Kim ,  Jeong-gun Lee

    Inventor： Su-hyeon Kim ,  Jeong-gun Lee

    IPC: B01L3/00 ,  G01N1/00 ,  C12M1/00

    CPC classification number: C12M47/06 ,  B01L3/5027 ,  C12N1/066 ,  C12N13/00 ,  G01N1/44 ,  Y10T137/2496 ,  Y10T436/25

    Abstract: A cell lysis device for lysing cells or viruses, comprising a cell lysis tube having a sample inlet; a pump connected to the cell lysis tube for transferring a sample into the tube; a sealing unit for reversibly sealing a specific region of the tube; and a laser source for generating a laser is provided. Further, a method of lysing cells or viruses using the cell lysis device is provided. The method comprises introducing a sample containing cells or viruses and optionally magnetic beads to the cell lysis tube through the sample inlet; transferring the sample to a specific region in the cell lysis tube by means of the pump; temporarily sealing the region of the cell lysis tube where the sample is placed with the sealing unit; irradiating the sample with the laser; removing the sealing unit from the cell lysis tube; and discharging the sample from the cell lysis tube by means of the pump.

    Abstract translation: 一种用于裂解细胞或病毒的细胞裂解装置，包括具有样品入口的细胞裂解管; 连接到细胞裂解管的泵，用于将样品转移到管中; 用于可逆地密封管的特定区域的密封单元; 并提供用于产生激光的激光源。 此外，提供了使用细胞裂解装置裂解细胞或病毒的方法。 该方法包括通过样品入口将含有细胞或病毒的样品和任选的磁珠引入细胞裂解管; 通过泵将样品转移到细胞裂解管中的特定区域; 用密封单元临时密封放置样品的细胞溶解管的区域; 用激光照射样品; 从细胞裂解管中取出密封单元; 并通过泵从细胞裂解管排出样品。

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