公开(公告)号：US07838806B2

公开(公告)日：2010-11-23

申请号：US11982548

申请日：2007-11-02

Applicant: Jan Weber

Inventor： Jan Weber

IPC: H05B6/36

CPC classification number: G01R33/286 ,  A61B5/055 ,  A61F2/82 ,  G01R33/3628 ,  Y10T29/49117

Abstract: An apparatus, system and method of a resonator device with an adjustable capacitor for allowing the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system. The resonator device includes an inductor coil, a conductive member, a sleeve having first and second sockets that receive at least portions of the inductor coil and the conductive member as electrodes to provide a capacitor structure. Dielectric material can be positioned between at least the first and second sockets, where changes in the cross sectional area defined by the induction coil cause changes in the capacitance value (C) as one or more of the electrodes move within the socket. Changes in the inductance and the capacitance values allow for the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system.

Abstract translation: 具有可调电容器的谐振器装置的装置，系统和方法，用于允许谐振器装置的谐振频率（F）继续与MRI系统的拉莫尔频率匹配。 谐振器装置包括电感线圈，导电构件，具有第一和第二插座的套筒，该套管至少容纳电感器线圈和导电构件的至少一部分作为电极以提供电容器结构。 介电材料可以位于至少第一和第二插座之间，其中由感应线圈限定的横截面积的变化引起电容值（C）的变化，因为一个或多个电极在插座内移动。 电感和电容值的变化允许谐振器装置的谐振频率（F）继续与MRI系统的拉莫尔频率匹配。

公开(公告)号：US20100286678A1

公开(公告)日：2010-11-11

申请号：US12838980

申请日：2010-07-19

Applicant: Jan Weber ,  John M. Hokanson ,  John H. Chen

Inventor： Jan Weber ,  John M. Hokanson ,  John H. Chen

IPC: A61B18/02 ,  A61B18/04 ,  A61M25/10

CPC classification number: A61M25/104 ,  A61F7/123 ,  A61L29/126 ,  A61M25/10 ,  B82Y5/00 ,  B82Y30/00

Abstract: Medical systems and methods including balloons having nanotubes are disclosed. In some embodiments, a medical system includes an elongated shaft, and an expandable balloon carried by the shaft and including nanotubes. The medical system is capable of cooling the balloon to less than about 37° C. In some embodiments, a method includes providing a medical device having an elongated shaft, and an expandable balloon carried by the elongated shaft and including nanotubes; and cooling the balloon to less than about 37° C.

Abstract translation: 公开了包括具有纳米管的气囊的医疗系统和方法。 在一些实施例中，医疗系统包括细长轴和由轴承载并包括纳米管的可膨胀气囊。 医疗系统能够将球囊冷却到小于约37℃。在一些实施例中，一种方法包括提供具有细长轴的医疗装置和由细长轴承载并包括纳米管的可膨胀气囊; 并将气球冷却至小于约37℃。

公开(公告)号：US20100280452A1

公开(公告)日：2010-11-04

申请号：US12835157

申请日：2010-07-13

Applicant: John Jianhua Chen ,  Jan Weber

Inventor： John Jianhua Chen ,  Jan Weber

IPC: A61M25/10 ,  A61K9/14 ,  A61K31/19 ,  A61K31/662 ,  A61K31/255 ,  A61K31/135 ,  A61K31/13 ,  A61K31/713 ,  A61K38/00 ,  A61P29/00 ,  A61P35/00 ,  A61P23/00 ,  A61P7/02 ,  A61P3/06

CPC classification number: A61L29/085 ,  A61L29/16 ,  A61L2300/608 ,  A61L2300/624

Abstract: Described herein are medical devices which are configured for implantation or insertion into a subject, preferably a mammalian subject. The medical devices contain one or more multilayer regions, which contain: (a) one or more (typically a plurality of) charged nanoparticle layers and (b) one or more (typically a plurality of) charged polyelectroyte layers. Such multilayers have a number of desirable attributes, including high strength, non-compliance, and flexibility. Also described herein are methods of making such devices.

公开(公告)号：US07799050B2

公开(公告)日：2010-09-21

申请号：US10838988

申请日：2004-05-05

Applicant: Joseph Hensley ,  Thomas E. Broome ,  Jan Weber

Inventor： Joseph Hensley ,  Thomas E. Broome ,  Jan Weber

IPC: A61M29/00

CPC classification number: A61F2/01 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2210/009 ,  A61F2230/005 ,  A61F2230/0067

Abstract: Devices and methods for magnetically centering and retrieving intravascular devices within a body lumen are disclosed. An intravascular filter in accordance with an illustrative embodiment may comprise an expandable filter structure having at least one magnetic element formed therein. The intravascular filter can be retrieved using a magnetic retrieval device that includes a magnetic retrieval mechanism for centering and retrieving the intravascular filter.

Abstract translation: 公开了用于磁体定心和取回体腔内的血管内装置的装置和方法。 根据说明性实施例的血管内过滤器可以包括其中形成有至少一个磁性元件的可膨胀过滤器结构。 血管内过滤器可以使用包括用于对中和取回血管内过滤器的磁回收机构的磁回收装置来取回。

公开(公告)号：US20100145437A1

公开(公告)日：2010-06-10

申请号：US12706881

申请日：2010-02-17

Applicant: Timothy S. Girton ,  Jeffrey S. Lindquist ,  David M. Knapp ,  Matt Heidner ,  Daniel Gregorich ,  Umang Anand ,  Peter Edelman ,  Matthew J. Miller ,  Raed Rizq ,  Jan Weber ,  Tracee Eidenschink ,  John J. Chen ,  Jaykeep Y. Kokate ,  Aparna Bhave ,  Kent D. Harrison ,  Graig L. Kveen ,  Benjamin Arcand ,  Michael Kuchling

Inventor： Timothy S. Girton ,  Jeffrey S. Lindquist ,  David M. Knapp ,  Matt Heidner ,  Daniel Gregorich ,  Umang Anand ,  Peter Edelman ,  Matthew J. Miller ,  Raed Rizq ,  Jan Weber ,  Tracee Eidenschink ,  John J. Chen ,  Jaykeep Y. Kokate ,  Aparna Bhave ,  Kent D. Harrison ,  Graig L. Kveen ,  Benjamin Arcand ,  Michael Kuchling

IPC: A61F2/82

CPC classification number: A61F2/91 ,  A61F2210/0076 ,  A61F2220/0066 ,  A61F2220/0083 ,  A61F2250/0067 ,  A61F2250/0068

Abstract: The invention is directed to mechanisms and methods that reduce the delamination of a therapeutic agent from a stent. The mechanisms include holes (channels, wells, and other hole configurations), protrusions, sintered metal cores, clamps/staples, pins, and stainless steel shields.

Abstract translation: 本发明涉及减少治疗剂从支架分层的机制和方法。 这些机构包括孔（通道，孔和其他孔构造），突起，烧结金属芯，夹/钉，销和不锈钢屏蔽。

公开(公告)号：US20100131004A1

公开(公告)日：2010-05-27

申请号：US12695941

申请日：2010-01-28

Applicant: Jan Weber ,  Tracee E.J. Eidenschink ,  David J. Sogard ,  Joel M. WasDyke ,  Thomas J. Holman

Inventor： Jan Weber ,  Tracee E.J. Eidenschink ,  David J. Sogard ,  Joel M. WasDyke ,  Thomas J. Holman

IPC: A61F2/01

CPC classification number: A61F2/01 ,  A61F2/24 ,  A61F2/2493 ,  A61F2/86 ,  A61F2002/018 ,  A61F2002/068 ,  A61F2230/0006 ,  A61F2230/0067

Abstract: Improved methods and apparatus for capturing emboli and subsequently removing or immobilizing the captured emboli are described. Emboli can be captured within a blood vessel and can be withdrawn to a position exterior to the blood vessel. Some filters can remain within a blood vessel yet direct emboli to a position exterior to the blood vessel.

Abstract translation: 描述了用于捕获栓塞以及随后去除或固定所捕获的栓塞的改进的方法和装置。 栓塞可以在血管内捕获并且可以撤回到血管外部的位置。 一些过滤器可以保留在血管内，但是直接栓塞到血管外部的位置。

公开(公告)号：US07725160B2

公开(公告)日：2010-05-25

申请号：US10216988

申请日：2002-08-12

Applicant: Jan Weber

Inventor： Jan Weber

IPC: A61B5/05

CPC classification number: G01R33/285 ,  G01R33/3628

Abstract: The present invention is directed to an MRI enhancing device deployable in a body. In one embodiment, the MRI enhancing device is formed of a wire loop and a capacitor that is at least partially formed by the wire used in forming the wire loop.

Abstract translation: 本发明涉及一种可在体内展开的MRI增强装置。 在一个实施例中，MRI增强装置由线环和至少部分地由形成线环的电线形成的电容器形成。

公开(公告)号：US20100057188A1

公开(公告)日：2010-03-04

申请号：US12200530

申请日：2008-08-28

Applicant: Jan Weber

Inventor： Jan Weber

IPC: A61F2/06

CPC classification number: A61L31/022 ,  A61L31/028 ,  A61L31/146 ,  A61L31/16 ,  A61L2300/608

Abstract: Endoprostheses include an endoprosthesis wall that includes a surface layer that includes a metallic material and that defines a plurality of pores. A therapeutic agent fills one or more pores of the surface layer and a non-polymeric coating, covers the therapeutic agent in the one or more pores. The endoprostheses can, for example, deliver a therapeutic agent, such as a drug, in a controlled manner over an extended period of time.

Abstract translation: 内假体包括内置假体壁，其包括包含金属材料并限定多个孔的表面层。 治疗剂填充表面层的一个或多个孔和非聚合物涂层，覆盖一个或多个孔中的治疗剂。 内用假体可以例如以长期的控制方式递送诸如药物的治疗剂。

公开(公告)号：US20100008970A1

公开(公告)日：2010-01-14

申请号：US12334113

申请日：2008-12-12

Applicant: Barry O'Brien ,  Ben Arcand ,  James Lee Shippy, III ,  Liliana Atanasoska ,  Aiden Flanagan ,  John T. Clarke ,  Tim O'Connor ,  Yixin Xu ,  Dave McMorrow ,  Jan Weber ,  John Kremer ,  Michael Kuehling ,  Dominique Seidel

Inventor： Barry O'Brien ,  Ben Arcand ,  James Lee Shippy, III ,  Liliana Atanasoska ,  Aiden Flanagan ,  John T. Clarke ,  Tim O'Connor ,  Yixin Xu ,  Dave McMorrow ,  Jan Weber ,  John Kremer ,  Michael Kuehling ,  Dominique Seidel

IPC: A61K31/337 ,  A61F2/00 ,  B05D1/02

CPC classification number: A61L31/088 ,  A61L31/16 ,  A61L2300/45 ,  A61L2300/61

Abstract: A drug-eluting endoprosthesis that includes a bioerodible metal portion and a therapeutic agent. In some aspects, the endoprosthesis includes a plurality of discrete deposits and a plurality of overlying layers each overlying one of the plurality of discrete deposits. Each discrete deposit includes one or more therapeutic agents and each overlying layer includes one or more bioerodible metals. In other aspects, the bioerodible metal portion includes at least two bioerodible metal regions having different electronegativities. The at least two bioerodible metal regions being in electrical contact with each other. The bioerodible metal erodes in a physiological environment to release the therapeutic agent.

Abstract translation: 包括生物腐蚀性金属部分和治疗剂的药物洗脱内用假体。 在一些方面，内假体包括多个离散沉积物和多个覆盖层，每个覆盖层覆盖多个离散沉积物之一。 每个离散沉积物包括一种或多种治疗剂，并且每个上覆层包括一种或多种生物可腐蚀金属。 在其他方面，生物腐蚀性金属部分包括具有不同电负性的至少两个生物可腐蚀金属区域。 所述至少两个生物浸渍金属区域彼此电接触。 生物腐蚀性金属在生理环境中侵蚀以释放治疗剂。

公开(公告)号：US20090319032A1

公开(公告)日：2009-12-24

申请号：US12486295

申请日：2009-06-17

Applicant: Jan Weber ,  Liliana Atanasoska ,  Michele Zoromski

Inventor： Jan Weber ,  Liliana Atanasoska ,  Michele Zoromski

IPC: A61F2/06 ,  B05D3/02

CPC classification number: A61F2/82 ,  A61L31/088 ,  A61L31/146

Abstract: An endoprosthesis, e.g., a stent (e.g., a drug eluting stent), that includes a porous surface and hollow elements integrated with a coating on the surface and a method of making the same are disclosed.

Abstract translation: 公开了一种内置假体，例如支架（例如，药物洗脱支架），其包括多孔表面和与表面上的涂层整合的中空元件及其制造方法。