公开(公告)号：US08366905B2

公开(公告)日：2013-02-05

申请号：US12850074

申请日：2010-08-04

Applicant: Kyu-tae Yoo ,  Seong-jin Kim ,  Eui-sik Yoon

Inventor： Kyu-tae Yoo ,  Seong-jin Kim ,  Eui-sik Yoon

IPC: G01N27/26 ,  H01L29/66

CPC classification number: G01N33/5438 ,  C12Q1/6825 ,  G01N27/4145

Abstract: An apparatus and method for detecting ionic materials includes a sensing electrode which contacts a liquid sample and detects a sensing voltage corresponding to a surface potential which is changed by a concentration of ionic materials in the liquid sample, a first switching transistor having a first terminal connected to the sensing electrode and a second terminal connected to a first node, a second switching transistor having a first terminal connected to a reset voltage and a second terminal connected to the first node, and a sensing transistor having a gate connected to the first node.

Abstract translation: 一种用于检测离子材料的装置和方法，包括一个感测电极，该感测电极接触液体样品并检测对应于由液体样品中的离子物质浓度改变的表面电位的感测电压，第一开关晶体管具有第一端子连接 耦合到感测电极和连接到第一节点的第二端子，具有连接到复位电压的第一端子和连接到第一节点的第二端子的第二开关晶体管，以及具有连接到第一节点的栅极的感测晶体管。

公开(公告)号：US08357957B2

公开(公告)日：2013-01-22

申请号：US12912191

申请日：2010-10-26

Applicant: Kyu-sang Lee ,  Kyu-tae Yoo ,  Jeo-young Shim ,  Jin-tae Kim ,  Yeon-ja Cho

Inventor： Kyu-sang Lee ,  Kyu-tae Yoo ,  Jeo-young Shim ,  Jin-tae Kim ,  Yeon-ja Cho

IPC: H01L29/78

CPC classification number: G01N33/54373 ,  C12Q1/6825 ,  G01N27/4145

Abstract: Provided are a FET-based sensor for detecting an ionic material, an ionic material detecting device including the FET-based sensor, and a method of detecting an ionic material using the FET-based sensor. The FET-based sensor includes: a sensing chamber including a reference electrode and a plurality of sensing FETs; and a reference chamber including a reference electrode and a plurality of reference FETs. The method includes: flowing a first solution into and out of the sensing chamber and the reference chamber of the FET-based sensor; flowing a second solution expected to contain an ionic material into and out of the sensing chamber while continuously flowing the first solution into and out of the reference chamber; measuring a current in a channel region between the source and drain of each of the sensing and reference FETs; and correcting the current of the sensing FETs.

Abstract translation: 提供了一种用于检测离子材料的基于FET的传感器，包括基于FET的传感器的离子材料检测装置，以及使用基于FET的传感器检测离子材料的方法。 基于FET的传感器包括：感测室，包括参考电极和多个感测FET; 以及包括参考电极和多个参考FET的参考室。 该方法包括：使第一溶液流入和流出基于FET的传感器的感测室和参考室; 使预期含有离子材料的第二溶液流入和流出感测室，同时使第一溶液持续流入和移出参考室; 测量每个感测和参考FET的源极和漏极之间的沟道区域中的电流; 并校正感测FET的电流。

公开(公告)号：US08293591B2

公开(公告)日：2012-10-23

申请号：US11733539

申请日：2007-04-10

Applicant: Jeo-young Shim ,  Kyu-tae Yoo ,  Kyu-sang Lee ,  Won-seok Chung ,  Yeon-ja Cho ,  Chang-eun Yoo

Inventor： Jeo-young Shim ,  Kyu-tae Yoo ,  Kyu-sang Lee ,  Won-seok Chung ,  Yeon-ja Cho ,  Chang-eun Yoo

IPC: H01L31/00

CPC classification number: H01L29/78 ,  G01N27/4145

Abstract: A field effect transistor for detecting an analyte having a thiol group includes a substrate, a source region and a drain region formed apart from each other on the substrate, the source region and the drain region being doped such that a polarity of the source and drain region is opposite to a polarity of the substrate, a channel region disposed between the source region and the drain region, an insulating layer formed of an electrically insulating material and disposed on the channel region, a gold layer disposed on the insulating layer and a reference electrode disposed apart from the gold layer.

Abstract translation: 用于检测具有硫醇基的分析物的场效应晶体管包括在衬底上彼此分开形成的衬底，源极区和漏极区，源极区和漏极区被掺杂，使得源极和漏极的极性 区域与基板的极性相反，设置在源极区域和漏极区域之间的沟道区域，由电绝缘材料形成并设置在沟道区域上的绝缘层，设置在绝缘层上的金层和参考 电极与金层分开设置。

公开(公告)号：US07981666B2

公开(公告)日：2011-07-19

申请号：US12833095

申请日：2010-07-09

Applicant: Kyu-tae Yoo ,  Joon-ho Kim ,  Jun-hong Min ,  Sung-ouk Jung ,  Ji-na Namgoong ,  Kui-hyun Kim ,  Jeo-young Shim ,  Kak Namkoong

Inventor： Kyu-tae Yoo ,  Joon-ho Kim ,  Jun-hong Min ,  Sung-ouk Jung ,  Ji-na Namgoong ,  Kui-hyun Kim ,  Jeo-young Shim ,  Kak Namkoong

IPC: C12M3/00

CPC classification number: G01N33/54373

Abstract: Provided are a sensing switch and a sensing method using the same. The sensing switch includes: a substrate; a supporter on the substrate; a sensing plate that is connected to a side of the supporter and is in parallel with the substrate by a predetermined distance; a receptor binding region on an upper surface of an end portion of the sensing plate; an electric or magnetic field generation device that induces deflection of the sensing plate when a receptor bound to the receptor binding region is selectively bound to an electrically or magnetically active ligand; and a pair of switching electrodes that are separated by a predetermined distance and is connected when the sensing plate contacts the substrate due to the deflection of the sensing plate. A target material need not be labelled, a signal processing of a fluorescent or electrical detection signal using an analysis apparatus is not required, and a signal can be directly decoded by confirming whether a current flows through the switch.

Abstract translation: 提供了一种感测开关和使用该感测开关的感测方法。 感测开关包括：基板; 底物上的支撑物; 感测板，其与所述支撑体的一侧连接并且与所述基板平行预定距离; 在感测板的端部的上表面上的受体结合区域; 当与受体结合区结合的受体选择性地结合到电或磁性活性配体时，引起感测板偏转的电场或磁场产生装置; 以及一对分离预定距离的开关电极，并且当感测板由于感测板的偏转而与基板接触时被连接。 目标材料不需要标注，不需要使用分析装置的荧光或电检测信号的信号处理，并且可以通过确认电流是否流过开关直接解码信号。

公开(公告)号：US20110010534A1

公开(公告)日：2011-01-13

申请号：US12757189

申请日：2010-04-09

Applicant: Kwang-hyeon LEE ,  Kyu-tae YOO

Inventor： Kwang-hyeon LEE ,  Kyu-tae YOO

IPC: G06F15/16 ,  H04L9/00

CPC classification number: G06F19/3418 ,  G06F19/00

Abstract: A method of displaying health information of a user, the method including: monitoring if a sharing request for a health information of a user is made by an external device, which provides a web page representing the health information of the user in the form of an image; downloading a captured image of the web page from the external device if the sharing request for the health information of the user is made; and displaying the downloaded captured image.

Abstract translation: 一种显示用户的健康信息的方法，所述方法包括：监视用户的健康信息的共享请求是否由外部设备进行，所述外部设备提供表示用户形式的用户的健康信息的网页 图片; 如果对用户的健康信息进行共享请求，则从外部设备下载捕获的网页图像; 并显示下载的捕获图像。

公开(公告)号：US20100289509A1

公开(公告)日：2010-11-18

申请号：US11939969

申请日：2007-11-14

Applicant: Won Seok CHUNG ,  Kyu Tae YOO ,  Jeo Young SHIM ,  Junghoon LEE ,  Misun CHA ,  Junglm HAN ,  Seungwon JUNG

Inventor： Won Seok CHUNG ,  Kyu Tae YOO ,  Jeo Young SHIM ,  Junghoon LEE ,  Misun CHA ,  Junglm HAN ,  Seungwon JUNG

IPC: G01R27/08

CPC classification number: G01N33/551 ,  G01N27/127 ,  G01N33/5438 ,  Y10S977/852

Abstract: A device and method are disclosed for detecting biomolecules. More specifically, by measuring the change in the electrical properties of a complex between a probe and carbon nanotubes, a non-label detection is achieved, capable of a rapid, sensitive and electrical detection of the presence and concentration of biomolecules in a sample solution.

Abstract translation: 公开了用于检测生物分子的装置和方法。 更具体地，通过测量探针和碳纳米管之间的络合物的电学性质的变化，实现了非标记检测，能够快速，灵敏和电检测样品溶液中生物分子的存在和浓度。

公开(公告)号：US20100181209A1

公开(公告)日：2010-07-22

申请号：US12637245

申请日：2009-12-14

Applicant: Kyu-tae YOO ,  Sung-ouk JUNG ,  Jun-hong MIN ,  Ji-na NAMGOONG ,  Soo-hyung CHOI ,  Jeo-young SHIM

Inventor： Kyu-tae YOO ,  Sung-ouk JUNG ,  Jun-hong MIN ,  Ji-na NAMGOONG ,  Soo-hyung CHOI ,  Jeo-young SHIM

IPC: G01N27/26

CPC classification number: G01N33/54306

Abstract: Provided is a method of sensing biomolecules using a bioFET, the method including: forming a layer including Au on a gate of the bioFET; forming a probe immobilized on a substrate separated from the gate by a predetermined distance, and a biomolecule having a thiol group (—SH) which is incompletely bonded to the probe; reacting the probe with a sample including a target molecule; and measuring a current flowing in a channel region between a source and a drain of the bioFET.

Abstract translation: 提供了一种使用bioFET感测生物分子的方法，该方法包括：在bioFET的栅极上形成包含Au的层; 形成固定在与栅极分离预定距离的基板上的探针，以及具有与探针不完全结合的硫醇基（-SH）的生物分子; 使探针与包含靶分子的样品反应; 以及测量在bioFET的源极和漏极之间的沟道区域中流动的电流。

公开(公告)号：US20100122087A1

公开(公告)日：2010-05-13

申请号：US12553297

申请日：2009-09-03

Applicant: Byung-soo GIM ,  Kyu-tae YOO ,  Kwang-hyeon LEE

Inventor： Byung-soo GIM ,  Kyu-tae YOO ,  Kwang-hyeon LEE

IPC: H04L9/32 ,  A61B5/00 ,  G06Q50/00

CPC classification number: G06F19/3418 ,  G06F19/00 ,  G06Q50/22 ,  H04L9/3226 ,  H04L63/0853 ,  H04L2209/80 ,  H04L2209/88 ,  H04W12/06 ,  H04W12/08

Abstract: A method of logging in a health information tele-monitoring device by using a personal portable device. The method includes issuing a security key embedded in a health information tele-monitoring device to a personal portable device, storing the security key issued by the health information tele-monitoring device in the user's personal portable device; requesting the user's personal portable device to authenticate the health information tele-monitoring device in order to connect the health information tele-monitoring device to a healthcare server; and authorizing access of the health information tele-monitoring device to the healthcare server.

Abstract translation: 一种通过使用个人便携式设备登录健康信息远程监视设备的方法。 该方法包括将嵌入在健康信息远程监视设备中的安全密钥发送到个人便携式设备，将由健康信息远程监视设备发布的安全密钥存储在用户的个人便携式设备中; 请求用户的个人便携式设备认证健康信息远程监控设备，以便将健康信息远程监控设备连接到保健服务器; 并授权将健康信息远程监控设备访问到医疗服务器。

公开(公告)号：US20090322354A1

公开(公告)日：2009-12-31

申请号：US11695905

申请日：2007-04-03

Applicant: Kyu-tae YOO ,  Kyu-sang LEE ,  Won-seok CHUNG ,  Jeo-young SHIM ,  Yeon-ja CHO

Inventor： Kyu-tae YOO ,  Kyu-sang LEE ,  Won-seok CHUNG ,  Jeo-young SHIM ,  Yeon-ja CHO

IPC: G01R27/08

CPC classification number: G01N33/54373

Abstract: A method of detecting a presence of bio-molecules, or a concentration of the target bio-molecules using a field effect transistor, includes allowing a first sample including a first target bio-molecule to contact a sensing surface of the field effect transistor and measuring a change in an electric signal of the field effect transistor, the field effect transistor including a substrate, a source region and a drain region, the source region and the drain region formed apart from each other on the substrate, the source region and the drain region each doped to having an opposite polarity than a polarity of the substrate, a channel region disposed between the source region and the drain region and an insulating layer including the sensing surface, the insulating layer disposed on the channel region.

Abstract translation: 使用场效应晶体管检测生物分子的存在或靶生物分子的浓度的方法包括允许包含第一靶生物分子的第一样品接触场效应晶体管的感测表面并测量 场效应晶体管的电信号的变化，所述场效应晶体管包括基板，源极区和漏极区，在所述基板上彼此分离形成的所述源极区和漏极区，所述源极区和漏极 每个被掺杂为具有与衬底的极性相反的极性，设置在源区和漏区之间的沟道区和包括感测表面的绝缘层，绝缘层设置在沟道区上。

公开(公告)号：US20080315861A1

公开(公告)日：2008-12-25

申请号：US12019765

申请日：2008-01-25

Applicant: Won Seok CHUNG ,  Kyu Tae YOO ,  Jeo Young SHIM ,  Jung Im HAN

Inventor： Won Seok CHUNG ,  Kyu Tae YOO ,  Jeo Young SHIM ,  Jung Im HAN

IPC: G01N33/68

CPC classification number: B01L3/502761 ,  B01L2300/0645 ,  B01L2300/0654 ,  B01L2400/0415 ,  G01N27/4145

Abstract: A biomolecule detector and a method thereof are provided to detect the biomolecules in a liquid sample using a field effect transistor (FET) array. The FET array is characterized in that the transistor used has no gate electrode layer, a reference electrode is provided in the space between the transistors in the array instead of the gate electrode layer. Using the FET array, the existence of the biomolecules in the sample can be detected electrically and effectively under the circumstance where an external voltage is applied to flow the biomolecules. Using the FET array to detect the biomolecules, the deviation for each transistor is reduced and the multiplex processing is also possible to measure the plurality of analyzing samples at the same time.

Abstract translation: 提供生物分子检测器及其方法以使用场效应晶体管（FET）阵列检测液体样品中的生物分子。 FET阵列的特征在于所使用的晶体管不具有栅电极层，参考电极设置在阵列中的晶体管之间的空间中，而不是栅极电极层。 使用FET阵列，可以在施加外部电压以使生物分子流动的情况下电性和有效地检测样品中的生物分子的存在。 使用FET阵列来检测生物分子，每个晶体管的偏差减小，并且多路复用处理也可以同时测量多个分析样本。