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公开(公告)号：US20100168847A1
公开(公告)日：2010-07-01
申请号：US12719758
申请日：2010-03-08
Applicant: Clifton A. Alferness , John M. Adams , Mark L. Mathis , David G. Reuter , Cruz Beeson , Leonard Kowalsky
Inventor： Clifton A. Alferness , John M. Adams , Mark L. Mathis , David G. Reuter , Cruz Beeson , Leonard Kowalsky
IPC: A61F2/24
CPC classification number: A61F2/2451 , A61F2250/001 , A61F2250/0059
Abstract: An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.
Abstract translation: 血管内支持装置包括支撑件或再生线，近端锚和远端锚。 支撑线接合血管壁以改变邻近其中放置血管内支架的血管的组织的形状。 锚和支撑线被设计成使得放置支撑件的容器保持打开，并且如果需要可以被其他装置访问。 该装置为在血管内流动的血液提供最小的金属表面积，以限制血栓形成。 锚固件可以锁定到位以将支撑件固定在容器内。
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公开(公告)号：US20100070050A1
公开(公告)日：2010-03-18
申请号：US12558206
申请日：2009-09-11
Applicant: Mark L. Mathis , David Thompson , Patrick Wu
Inventor： Mark L. Mathis , David Thompson , Patrick Wu
CPC classification number: A61B17/12104 , A61B5/087 , A61B5/091 , A61B5/14542 , A61B5/4848 , A61B6/032 , A61B17/12022 , A61B17/12131 , A61B17/1214 , A61B17/12145 , A61B17/12172 , A61B17/1285 , A61B17/24 , A61B90/00 , A61B2017/00477 , A61B2017/00809 , A61B2017/12054 , A61B2034/108 , A61B2090/061 , A61B2090/3966 , A61M16/04 , A61M16/0406 , A61M16/0833 , A61M2205/0266
Abstract: A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
Abstract translation: 公开了一种肺容积减小系统，其包括可植入装置，其适于以递送配置递送到患者的肺气道并且改变为展开的配置以弯曲肺气道。 本发明还公开了一种弯曲患者的肺气道的方法，包括将装置以输送构造插入气道并将装置弯曲成展开构型，从而弯曲气道。
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公开(公告)号：US07674287B2
公开(公告)日：2010-03-09
申请号：US11467105
申请日：2006-08-24
Applicant: Clifton A. Alferness , John M. Adams , Mark L. Mathis , David G. Reuter , Cruz Beeson , Leonard Kowalsky
Inventor： Clifton A. Alferness , John M. Adams , Mark L. Mathis , David G. Reuter , Cruz Beeson , Leonard Kowalsky
CPC classification number: A61F2/2451 , A61F2250/001 , A61F2250/0059
Abstract: An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.
Abstract translation: 血管内支持装置包括支撑件或再生线，近端锚和远端锚。 支撑线接合血管壁以改变邻近其中放置血管内支架的血管的组织的形状。 锚和支撑线被设计成使得放置支撑件的容器保持打开，并且如果需要可以被其他装置访问。 该装置为在血管内流动的血液提供最小的金属表面积，以限制血栓形成。 锚固件可以锁定到位以将支撑件固定在容器内。
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公开(公告)号：US20090076623A1
公开(公告)日：2009-03-19
申请号：US12209662
申请日：2008-09-12
Applicant: Mark L. Mathis , David Thompson , Nathan Aronson , Patrick Wu
Inventor： Mark L. Mathis , David Thompson , Nathan Aronson , Patrick Wu
CPC classification number: A61M16/208 , A61B1/018 , A61B1/04 , A61B1/2676 , A61B5/06 , A61B6/032 , A61B6/12 , A61B6/485 , A61B17/00234 , A61B17/12022 , A61B17/12031 , A61B17/12104 , A61B17/12131 , A61B17/1214 , A61B17/12145 , A61B17/1215 , A61B17/12172 , A61B90/00 , A61B90/02 , A61B2017/00477 , A61B2017/00809 , A61B2017/00867 , A61B2017/12054 , A61F2/04 , A61F2002/043 , A61F2002/046 , A61M16/04 , A61M16/0406 , A61M16/0833 , A61M37/0069 , A61M2205/0266 , A61M2205/32
Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. A lung volume reduction system includes an implantable device having an elongate body that is sized and shaped for delivery via the airway system to a lung airway of a patient. The implant is inserted and positioned while the implant is in a delivery configuration, and is reconfigured to a deployed configuration so as to locally compress adjacent tissue of the lung, with portions of the elongate body generally moving laterally within the airway so as to laterally compress lung tissue. A plurality of such implants will often be used to treat a lung of a patient.
Abstract translation: 本发明提供改进的医疗装置，治疗处理系统和用于治疗肺的治疗方法。 肺容积减小系统包括可植入装置，其具有细长体，其尺寸和形状用于经由气道系统输送到患者的肺气道。 植入物在植入物处于输送构型中时被插入和定位，并且被重新配置为展开构型，以便局部压缩肺的邻近组织，细长体的一部分通常在气道内侧向移动，以便横向压缩 肺组织。 多个这样的植入物将经常用于治疗患者的肺部。
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公开(公告)号：US07503932B2
公开(公告)日：2009-03-17
申请号：US11279352
申请日：2006-04-11
Applicant: Mark L. Mathis , Gregory Nieminen , Nathan Aronson , Garrett Beget
Inventor： Mark L. Mathis , Gregory Nieminen , Nathan Aronson , Garrett Beget
IPC: A61F2/06
CPC classification number: A61F2/2451
Abstract: The present invention relates to a medical device and uses thereof that supports or changes the shape of tissue near a vessel in which the device is placed. The present invention is particularly useful in reducing mitral valve regurgitation by changing the shape of or supporting a mitral valve annulus. The device includes a support structure, a proximal anchor adapted to be positioned in a superior vena cava, and a distal anchor adapted to be positioned in a coronary sinus. The support structure engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed.
Abstract translation: 本发明涉及一种医疗装置及其用途，其用于支撑或改变其中放置该装置的血管附近的组织的形状。 本发明特别可用于通过改变二尖瓣环的形状或支撑二尖瓣环来减少二尖瓣反流。 该装置包括支撑结构，适于定位在上腔静脉中的近端锚，以及适于定位在冠状窦中的远侧锚。 支撑结构接合血管壁以改变邻近其中放置血管内支持物的血管的组织的形状。
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Patent Agency Ranking
公开(公告)号：US20080288060A1
公开(公告)日：2008-11-20
申请号：US11631832
申请日：2005-07-06
Applicant: David Martin Kaye , John Melmouth Power , Clifton A. Alferness , Adam Lucas Bilney , Mark L. Mathis
Inventor： David Martin Kaye , John Melmouth Power , Clifton A. Alferness , Adam Lucas Bilney , Mark L. Mathis
IPC: A61F2/24
CPC classification number: A61B17/0401 , A61B17/0487 , A61B17/064 , A61B17/068 , A61B17/221 , A61B2017/00243 , A61B2017/0409 , A61B2017/0441 , A61B2017/0445 , A61B2017/0448 , A61B2017/0453 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/0649 , A61B2017/081 , A61B2017/2215 , A61F2/2445
Abstract: In a method of treating valvular insufficiency in a patient, a plurality of filaments (2) are used to engage tissue at spaced apart locations of an annulus (1) of the valve being treated. The engaged filaments (2) are drawn inward so as to draw the engaged tissue around the valve annulus (1) inward. The filaments (2) are then secured with the engaged tissue in the drawn-in configuration. Inward drawing of the engaged tissue improves valve function by reducing the valve annulus (1). Alternatively or additionally, anchor means may be used to secure the filaments to a region of robust tissue, thus drawing the engaged tissue toward the anchor means to further improve valve function.
Abstract translation: 在治疗患者瓣膜功能不全的方法中，多个细丝（2）用于在所治疗的瓣膜（1）的间隔开的位置处接合组织。 所接合的细丝（2）向内拉，以便将所接合的组织向内抽吸到瓣膜环（1）周围。 然后，细丝（2）以接合的组织固定在牵引构造中。 通过减小瓣膜环（1）来改变接合组织的内部抽吸来提高瓣膜功能。 或者或另外，锚固装置可以用于将细丝固定到坚固的组织的区域，从而将接合的组织拉向锚固装置以进一步改善瓣膜功能。
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公开(公告)号：US06908478B2
公开(公告)日：2005-06-21
申请号：US10011867
申请日：2001-12-05
Applicant: Clifton A. Alferness , John M. Adams , Mark L. Mathis , David G. Reuter
Inventor： Clifton A. Alferness , John M. Adams , Mark L. Mathis , David G. Reuter
CPC classification number: A61F2/2451 , A61F2/2466
Abstract: A device, system, and method effects mitral valve annulus geometry of a heart. The device includes a first anchor configured to be positioned within and fixed to the coronary sinus of the heart adjacent the mitral valve annulus within the heart. A cable is fixed to the first anchor and extends proximately therefrom and slidingly through a second anchor which is positioned and fixed in the heart proximal to the first anchor. A lock locks the cable to the second anchor when tension is applied to the cable for effecting the mitral valve annulus geometry.
Abstract translation: 一种装置，系统和方法影响心脏的二尖瓣环形几何。 该装置包括构造成定位在心脏内邻近二尖瓣环的心脏的冠状窦内并固定到其的冠状窦的第一锚。 电缆固定到第一锚固件并且从其向近侧延伸并且滑动地穿过定位并固定在靠近第一锚固件的心脏中的第二锚固件。 当拉索施加到电缆以实现二尖瓣环形几何时，锁将电缆锁定到第二锚定器。
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公开(公告)号：US06824562B2
公开(公告)日：2004-11-30
申请号：US10142637
申请日：2002-05-08
Applicant: Mark L. Mathis , Leonard Kowalsky , David G. Reuter , Cruz Beeson
Inventor： Mark L. Mathis , Leonard Kowalsky , David G. Reuter , Cruz Beeson
IPC: A61F206
CPC classification number: A61F2/2451 , A61F2/2466 , A61F2002/91591 , A61F2210/0014 , A61F2220/0091 , A61F2230/0023 , A61F2250/0004 , A61F2250/0008 , A61F2250/0012 , A61F2250/0086 , A61F2310/00017 , A61F2310/00023
Abstract: An anchor anchors a therapeutic device having an elongated body within a body lumen. The anchor includes a fixation member carried on the device which is adjustable from a first configuration that permits placement of the device in the body lumen to a second configuration that anchors the device within the body lumen. The anchor further includes a lock that locks the fixation member in the second configuration. The fixation member may be locked in any one of a plurality of intermediate points between the first configuration and a maximum second configuration.
Abstract translation: 锚定器将具有细长体的治疗装置锚定在体腔内。 所述锚固件包括承载在所述装置上的固定构件，所述固定构件可从第一构造调节，所述第一构型允许将所述装置放置在所述体腔内到达将所述装置固定在所述体腔内的第二构造。 锚固件还包括将固定构件锁定在第二构造中的锁。 固定构件可以锁定在第一构造和最大第二构造之间的多个中间点中的任何一个中。
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公开(公告)号：US5599341A
公开(公告)日：1997-02-04
申请号：US259886
申请日：1994-06-15
Applicant: Mark L. Mathis , Thomas A. Silvestrini
Inventor： Mark L. Mathis , Thomas A. Silvestrini
CPC classification number: A61F9/008 , A61F9/00804 , A61F2009/00853 , A61F2009/00872
Abstract: This invention is a procedure and system for the correction of optical abnormalities in a hum, a eye. It involves the use of laser radiation to desiccate or ablate tissue in the stromal layer of the cornea. The procedure involved the initial step of forming at least one access site allowing access to the corneal volume behind Bowman's layer. The laser probe is then introduced into the access site and, depending upon the visual abnormality to be corrected, the probe is activated to adjust the volume of the corneal stromal layers. The shape of the volume desiccated or ablated is dependent upon the aberration to be corrected. In certain circumstances, radial or circumferential cuts in Bowman's layer may allow the curvature of the cornea to change following the corneal volume adjustment.
Abstract translation: 本发明是用于校正嗡嗡声，眼睛中的光学异常的程序和系统。 它涉及使用激光辐射来干燥或消融角膜基质层中的组织。 该程序涉及形成至少一个访问站点的初始步骤，允许访问Bowman层后面的角膜体积。 然后将激光探针引入进入位置，并且根据要校正的视觉异常，激活探针以调节角膜基质层的体积。 干燥或消融的体积的形状取决于要校正的像差。 在某些情况下，Bowman层中的径向或周向切割可允许角膜体积调整后角膜的曲率改变。
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公开(公告)号：US20210330460A1
公开(公告)日：2021-10-28
申请号：US17305559
申请日：2021-07-09
Applicant: Mark L. MATHIS , Gregory D. NIEMINEN , Nathan ARONSON , Garrett R. BEGET
Inventor： Mark L. MATHIS , Gregory D. NIEMINEN , Nathan ARONSON , Garrett R. BEGET
IPC: A61F2/24
Abstract: An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.
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