公开(公告)号：US09663774B2

公开(公告)日：2017-05-30

申请号：US14725470

申请日：2015-05-29

Applicant: Novozymes Inc.

Inventor： Nikolaj Spodsberg ,  Tarana Shagasi

IPC: C12N9/42 ,  C12P21/06 ,  C12P19/34 ,  C07H21/04 ,  C07K1/00

CPC classification number: C12N9/2437 ,  C12Y302/01004

Abstract: The present invention relates to isolated polypeptides having endoglucanase activity, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains.

公开(公告)号：US20170145462A1

公开(公告)日：2017-05-25

申请号：US15418280

申请日：2017-01-27

Applicant: Novozymes, Inc.

Inventor： Jeffrey Shasky ,  Wendy Yoder

IPC: C12P21/00 ,  C12N9/88 ,  C12N9/58 ,  C12N15/80 ,  C12N9/30

CPC classification number: C12P21/00 ,  C12N9/242 ,  C12N9/58 ,  C12N9/88 ,  C12N15/80 ,  C12P21/02 ,  C12Y302/01001 ,  C12Y401/01023 ,  Y02P20/52

Abstract: The present invention relates to methods of producing a polypeptide, comprising: (a) cultivating a mutant of a parent Fusarium venenatum strain in a medium for the production of the polypeptide, wherein the mutant strain comprises a polynucleotide encoding the polypeptide and one or more (several) genes selected from the group consisting of pyrG, amyA, and alpA, wherein the one or more (several) genes are modified rendering the mutant strain deficient in the production of one or more (several) enzymes selected from the group consisting of orotidine-5′-monophosphate decarboxylase, alpha-amylase, and alkaline protease, respectively, compared to the parent Fusarium venenatum strain when cultivated under identical conditions; and (b) recovering the polypeptide from the cultivation medium. The present invention also relates to enzyme-deficient mutants of Fusarium venenatum strains and methods for producing such mutants.

公开(公告)号：US09624481B2

公开(公告)日：2017-04-18

申请号：US14357611

申请日：2012-11-30

Applicant: Novozymes Inc.

Inventor： Ye Liu ,  Lan Tang ,  Yu Zhang ,  Junxin Duan

IPC: A01H5/10 ,  C12N15/82 ,  C12N15/55 ,  C12P7/10 ,  C12N9/42 ,  C12P19/14 ,  C12P19/02

CPC classification number: C12N9/2482 ,  C12N9/2434 ,  C12P7/10 ,  C12P19/02 ,  C12P19/14 ,  C12P2203/00 ,  C12Y302/01008 ,  C12Y302/01037 ,  D21C5/005

Abstract: Provided are isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. Also provided are nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

公开(公告)号：US20170088869A1

公开(公告)日：2017-03-30

申请号：US15175645

申请日：2016-06-07

Applicant: Novozymes, Inc. ,  Novozymes North America, Inc.

Inventor： Jason Quinlan ,  Feng Xu ,  Matt Sweeney ,  Don Higgins ,  Hui Xu

IPC: C12P19/14 ,  C07K14/385 ,  C07K14/37 ,  C07K14/38 ,  C12P19/02 ,  C12N9/42

CPC classification number: C12P19/14 ,  C07K14/37 ,  C07K14/38 ,  C07K14/385 ,  C12N9/2437 ,  C12N9/2445 ,  C12N9/96 ,  C12P5/002 ,  C12P5/02 ,  C12P5/026 ,  C12P7/10 ,  C12P7/26 ,  C12P7/28 ,  C12P7/40 ,  C12P13/04 ,  C12P19/02 ,  C12P19/12 ,  C12P2201/00 ,  C12P2203/00 ,  C12Y302/01004 ,  C12Y302/01021 ,  Y02E50/16

Abstract: The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a liquor. The present invention also relates to methods of using the compositions.

公开(公告)号：US09428742B2

公开(公告)日：2016-08-30

申请号：US13959577

申请日：2013-08-05

Applicant: Novozymes A/S ,  Novozymes, Inc.

Inventor： Soren Flensted Lassen ,  Paul Harris ,  Elena Vlasenko ,  Kristian Krogh

IPC: C12N9/24 ,  C12N15/00 ,  C12N9/42

CPC classification number: C12N9/2434 ,  C12N9/2437 ,  C12Y302/01004

Abstract: The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

公开(公告)号：US20160230158A1

公开(公告)日：2016-08-11

申请号：US15139007

申请日：2016-04-26

Applicant: Novozymes, Inc.

Inventor： Yu Zhang ,  Junxin Duan ,  Lan Tang ,  Wenping Wu

IPC: C12N9/42

CPC classification number: C12N9/2437 ,  C07K14/37 ,  C12N9/2434 ,  C12P5/002 ,  C12P5/02 ,  C12P5/026 ,  C12P7/02 ,  C12P13/04 ,  C12P19/02 ,  C12P19/14 ,  C12P2201/00 ,  C12P2203/00 ,  C12Y302/01004 ,  Y02E50/343 ,  Y02P20/52

Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

公开(公告)号：US09404091B2

公开(公告)日：2016-08-02

申请号：US14875452

申请日：2015-10-05

Applicant: Novozymes, Inc. ,  Novozymes A/S

Inventor： Monica Tassone ,  Leonardo De Maria

IPC: C12N9/04 ,  C12P7/42 ,  C12P7/52

CPC classification number: C12N9/0006 ,  C12P7/42 ,  C12P7/52 ,  C12Y101/01059 ,  C12Y101/01276 ,  C12Y101/01298 ,  Y02P20/52

Abstract: The present invention relates to 3-hydroxypropionate dehydrogenase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US09376670B2

公开(公告)日：2016-06-28

申请号：US14277231

申请日：2014-05-14

Applicant: Novozymes Inc.

Inventor： Nikolaj Spodsberg

IPC: C12N9/42 ,  C12P19/14 ,  C12P7/14 ,  C12P19/02

CPC classification number: C12N9/2437 ,  C12P7/14 ,  C12P19/02 ,  C12P19/14 ,  C12P2203/00 ,  C12Y302/01091 ,  Y02E50/16 ,  Y02P20/52

Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

公开(公告)号：US20160145667A1

公开(公告)日：2016-05-26

申请号：US15009514

申请日：2016-01-28

Applicant: Novozymes A/S ,  Novozymes, Inc.

Inventor： Mads Bjornvad ,  Debbie Yaver

IPC: C12P21/02 ,  C12N9/20

CPC classification number: C12P21/02 ,  C07K14/37 ,  C07K2319/02 ,  C12N9/20 ,  C12N15/625 ,  C12N15/81 ,  C12Y301/01003

Abstract: The present invention relates to methods for producing a polypeptide having biological activity, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first polynucleotide encoding the polypeptide operably linked to a second polynucleotide encoding a variant signal peptide or a variant prepropeptide; and (b) isolating the secreted polypeptide having biological activity from the cultivation medium.

公开(公告)号：US20160145663A1

公开(公告)日：2016-05-26

申请号：US14885555

申请日：2015-10-16

Applicant: Novozymes, Inc.

Inventor： Brett McBrayer ,  Tarana Shaghasi ,  Elena Vlasenko

IPC: C12P19/14 ,  C12P19/12 ,  C12P19/02 ,  C12N9/42 ,  C12N9/24

CPC classification number: C12P19/14 ,  C12N1/22 ,  C12N9/2402 ,  C12N9/2437 ,  C12N9/2445 ,  C12N9/248 ,  C12P19/02 ,  C12P19/12 ,  C12P21/02 ,  C12P2203/00 ,  C12Y302/01 ,  C12Y302/01004 ,  C12Y302/01008 ,  C12Y302/01021 ,  C12Y302/01037 ,  C12Y302/01091 ,  Y02P20/52

Abstract: The present invention relates to enzyme compositions for high temperature saccharification of cellulosic material and to uses thereof.