公开(公告)号：US20210018475A1

公开(公告)日：2021-01-21

申请号：US16929062

申请日：2020-07-14

Applicant: Agilent Technologies, Inc.

Inventor： Clemens Plachetka ,  Manfred Berndt ,  Konstantin Shoykhet

IPC: G01N30/34 ,  B01F13/08 ,  B01F3/08 ,  G01N30/16 ,  G01N30/80 ,  F16K29/00 ,  F16K11/00

Abstract: A mixer for mixing a mobile phase in a sample separation device for separating a fluidic sample, wherein the mixer includes a fluid inlet for supplying the mobile phase to be mixed to a mixing volume, a movable body configured for rotating and axially moving in the mixing volume to thereby mix the mobile phase, and a fluid outlet for supplying the mixed mobile phase to a mobile phase consumer.

公开(公告)号：US10830739B2

公开(公告)日：2020-11-10

申请号：US15500706

申请日：2015-05-28

Applicant: Agilent Technologies, Inc.

Inventor： Herbert Anderer ,  Konstantin Shoykhet ,  Klaus Witt ,  Stephan Buckenmaier

IPC: G01N30/46 ,  G01N30/82 ,  G01N30/22 ,  G01N30/24 ,  B01D15/18 ,  B01D15/24 ,  G01N30/44 ,  G01N30/20 ,  G01N30/84 ,  G01N30/02

Abstract: In a method for processing successive fluidic sample portions provided by a sample source, sample reception volumes are filled successively temporarily with at least a respective one of the sample sections, and the sample sections are emptied successively out of the sample reception volumes in such a way, that, while emptying, it is avoided to bring two respective ones of the sample sections, which have not left the sample source directly adjacent to one another, in contact with one another.

公开(公告)号：US20200340956A1

公开(公告)日：2020-10-29

申请号：US16760429

申请日：2018-10-26

Applicant: Agilent Technologies, Inc.

Inventor： Thomas Ortmann ,  Konstantin Shoykhet

IPC: G01N30/20 ,  G01N30/08 ,  G01N30/32 ,  G01N30/36

Abstract: Injector (40) for injecting a fluidic sample into a mobile phase in a sample separation apparatus (10), the injector (40) comprising a main flow path (100) between a fluid drive (20) and a sample separation device (30), wherein the fluid drive (20) is adapted to drive the mobile phase and the sample separation device (30) is adapted to separate the fluidic sample that is injected into the mobile phase, a discharge device (104) for discharging an, in particular predetermined, amount of the mobile phase from the main flow path (100), and a supply device (102) for supplying an, in particular predetermined, amount of the fluidic sample and/or of a solvent into the main flow path (100), wherein the discharged amount and the supplied amount compensate each other at least partially.

公开(公告)号：US10761071B2

公开(公告)日：2020-09-01

申请号：US15558117

申请日：2016-03-10

Applicant: Agilent Technologies, Inc.

Inventor： Dwight Robert Stoll ,  Konstantin Shoykhet ,  Klaus Witt ,  Stephan Buckenmaier

IPC: G01N30/34 ,  G01N30/46 ,  G01N30/20

Abstract: A control device for controlling at least part of a sample separation apparatus for separating a fluidic sample, the sample separation apparatus including at least two fluid accommodation volumes having different flow through properties and each being configured for temporarily accommodating fluidic sample, wherein the control device is configured for controlling operation of at least part of the sample separation apparatus for at least partially compensating sample separation artifacts resulting from the different flow through properties of the fluid accommodation volumes.

公开(公告)号：US10281058B2

公开(公告)日：2019-05-07

申请号：US14975342

申请日：2015-12-18

Applicant: Agilent Technologies, Inc.

Inventor： Konstantin Shoykhet ,  Klaus Witt ,  Stephan Buckenmaier ,  Dwight Stoll

IPC: B01D15/14 ,  G01N30/20 ,  G01N30/46 ,  F16K99/00 ,  G01N30/32 ,  B01D15/18 ,  B01D15/10 ,  B01L3/00 ,  G01N27/447 ,  B01D15/40

Abstract: A fluid processing device (10) for processing fluid, wherein the fluid processing device (10) comprises a first fluid drive unit (20) configured for driving a first fluid along a first flow path (85), a second fluid drive unit (20′) configured for driving a second fluid along a second flow path (86), and a fluidic switch (90) fluidically coupled to the first flow path (85) and to the second flow path (86) and configured for being switchable for transferring first fluid from the first flow path (85) into the second flow path (86) without interruption of fluid flow along at least one of the first flow path (85) and the second flow path (86).

公开(公告)号：US20170131245A1

公开(公告)日：2017-05-11

申请号：US15320185

申请日：2015-06-25

Applicant: Agilent Technologies, Inc.

Inventor： Dwight Robert Stoll ,  Stephan Buckenmaier ,  Klaus Witt ,  Konstantin Shoykhet

IPC: G01N30/46 ,  G01N30/32 ,  B01D15/18

CPC classification number: G01N30/463 ,  B01D15/1878 ,  G01N30/32 ,  G01N30/465 ,  G01N30/88 ,  G01N2030/322 ,  G01N2030/8881

Abstract: A secondary stage sample separation device for separating at least a portion of a fluidic sample includes a fluidic interface configured for forming a fluidic coupling between a primary stage sample separation device and the secondary separation device, so that the fluidic sample separated by the primary stage sample separation device is fluidically suppliable to the secondary stage sample separation device via the fluidic interface for further separation, and a pressure reduction mechanism configured for reducing pressure at the fluidic interface at least in the event of an overpressure or of an excessive pressure increase.