公开(公告)号：US06667189B1

公开(公告)日：2003-12-23

申请号：US10243906

申请日：2002-09-13

Applicant: Zhe Wang ,  Qingxin Zhang ,  Hanhua Feng

Inventor： Zhe Wang ,  Qingxin Zhang ,  Hanhua Feng

IPC: H01L2100

CPC classification number: H04R19/005 ,  Y10T29/49005

Abstract: A silicon condenser microphone is described. The silicon condenser microphone of the present invention comprises a perforated backplate comprising a portion of a single crystal silicon substrate, a support structure formed on the single crystal silicon substrate, and a floating silicon diaphragm supported at its edge by the support structure and lying parallel to the perforated backplate and separated from the perforated backplate by an air gap.

Abstract translation: 描述了硅电容麦克风。 本发明的硅电容麦克风包括一个多孔背板，它包括单晶硅衬底的一部分，形成在单晶硅衬底上的一个支撑结构，以及一个浮动硅隔膜，其支撑结构在其边缘平行于 穿孔背板并通过气隙与多孔背板隔开。

公开(公告)号：US06562963B2

公开(公告)日：2003-05-13

申请号：US09919564

申请日：2001-07-31

Applicant: Roberta L. Dorow ,  Silvio Campagna ,  Pasquale N. Confalone ,  Fuqiang Jin ,  Zhe Wang

Inventor： Roberta L. Dorow ,  Silvio Campagna ,  Pasquale N. Confalone ,  Fuqiang Jin ,  Zhe Wang

IPC: C07C23101

CPC classification number: C07C69/007 ,  C07C43/315 ,  C07C59/58 ,  C07C235/28 ,  C07D267/00 ,  C07D273/02

Abstract: The present invention is directed to a process for the preparation of a compound of formula (X-a) or a pharmaceutically acceptable salt form thereof, wherein: R1 is selected from the group consisting of: C1-5 alkyl substituted with 0-5 R1a, —(CH2)r—C3-10 cycloalkyl substituted with 0-5 R1a, and —(CH2)r-aryl substituted with 0-5 R1a. Compounds of Formula (X-a) are macrocyclic molecules containing anti-succinate residues which inhibit metalloproteinases such as aggrecanase, and the production of tumor necrosis factor (TNF). The anti-succinates are formed by an Ireland Claisen rearrangement of a silyl ketene acetal which proceeds with high stereoselectivity.

Abstract translation: 本发明涉及制备式（Xa）化合物或其药学上可接受的盐形式的方法，其中：R 1选自：被0-5个R 1a取代的C 1-5烷基， - （O）R-C3-10环烷基取代有0-5个R 1a和 - （CH 2）r - 被0-5个R 1a取代的芳基。式（Ⅹa）化合物是含有抗琥珀酸残基的大环分子，其抑制金属蛋白酶如 聚集蛋白聚糖酶，以及肿瘤坏死因子（TNF）的产生。 抗琥珀酸盐由爱立信选择性的甲硅烷基乙烯酮缩醛的爱尔兰克莱森重排形成。

公开(公告)号：US09526769B2

公开(公告)日：2016-12-27

申请号：US11759080

申请日：2007-06-06

Applicant: Ying Sun ,  Deqiang Niu ,  Guoyou Xu ,  Yat Sun Or ,  Zhe Wang

Inventor： Ying Sun ,  Deqiang Niu ,  Guoyou Xu ,  Yat Sun Or ,  Zhe Wang

IPC: A61K38/00 ,  A61K38/48 ,  A61K38/21 ,  A61K38/45 ,  A61K38/52 ,  C07K5/083 ,  C07K5/087 ,  C07K7/06

CPC classification number: A61K38/4886 ,  A61K38/21 ,  A61K38/212 ,  A61K38/215 ,  A61K38/45 ,  A61K38/52 ,  C07K5/0804 ,  C07K5/0812 ,  C07K7/06 ,  A61K2300/00

Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract translation: 本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其抑制丝氨酸蛋白酶活性，特别是丙型肝炎病毒（HCV）NS3-NS4A蛋白酶的活性。 因此，本发明的化合物干扰丙型肝炎病毒的生命周期，也可用作抗病毒剂。 本发明还涉及药物组合物，其包含用于给患有HCV感染的受试者施用的上述化合物。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的HCV感染的方法。

公开(公告)号：US20140036253A1

公开(公告)日：2014-02-06

申请号：US14000356

申请日：2011-08-30

Applicant: Zhe Wang ,  Zheng Li ,  Tingbi Yuan ,  Lizhi Li ,  Jie Feng

Inventor： Zhe Wang ,  Zheng Li ,  Tingbi Yuan ,  Lizhi Li ,  Jie Feng

IPC: G01J3/02 ,  G01J3/44

CPC classification number: G01J3/0202 ,  G01J3/44 ,  G01N1/286 ,  G01N21/274 ,  G01N21/718

Abstract: The present invention provides a method and a system for improving the precision of element measurement based on laser-induced breakdown spectroscopy. The method comprises: press-forming a sample to be measured with a tablet press; making a hole on or immediately above a surface of the press formed sample; forming a layer of aerosol immediately above the surface of the sample to be measured with the components thereof completely identical to those of the sample to be measured; testing the sample to be measured by using a laser-induced breakdown spectroscopic system, so as to obtain the intensities of the characteristic spectral lines of a target element in the sample to be measured; and determining the concentration of the target element in the sample to be measured according to a calibration curve of the target element in prearranged calibration samples.

Abstract translation: 本发明提供一种基于激光诱导击穿光谱法提高元件测量精度的方法和系统。 该方法包括：用压片机压制成型待测样品; 在压制成形样品的表面上或紧邻上方形成孔; 在待测样品表面正上方形成一层气溶胶，其成分与待测样品完全相同; 通过使用激光诱导击穿光谱系统测试要测量的样品，以获得待测样品中目标元素的特征谱线的强度; 以及根据预定校准样品中的目标元素的校准曲线确定待测样品中的目标元素的浓度。

公开(公告)号：US20140018380A1

公开(公告)日：2014-01-16

申请号：US14003174

申请日：2012-01-31

Applicant: Dengming Xiao ,  Yan Zhu ,  Yuandong Hu ,  Huting Wang ,  Yuliang Liu ,  Jijun Li ,  Deguang Sun ,  Zhe Wang ,  Yongheng Wei ,  Zanping Wang ,  Guojing Tang ,  Lutao Jing

Inventor： Dengming Xiao ,  Yan Zhu ,  Yuandong Hu ,  Huting Wang ,  Yuliang Liu ,  Jijun Li ,  Deguang Sun ,  Zhe Wang ,  Yongheng Wei ,  Zanping Wang ,  Guojing Tang ,  Lutao Jing

IPC: C07D401/04 ,  C07D471/04 ,  C07D413/14 ,  C07D401/14

CPC classification number: C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D413/14 ,  C07D451/14 ,  C07D471/04

Abstract: The present invention provides a new class of bicyclic heteroaryl compounds represented by Formula I, pharmaceutical compositions containing these compounds, and their use for modulating the activity of GPR119 in the treatment of metabolic disorders and complications thereof, as well as methods for the treatment of the metabolic disorders and complications thereof.

Abstract translation: 本发明提供了一类由式I表示的双环杂芳基化合物，含有这些化合物的药物组合物及其用于调节GPR119在治疗代谢紊乱及其并发症中的活性的用途，以及用于治疗 代谢紊乱及其并发症。

公开(公告)号：US20130335196A1

公开(公告)日：2013-12-19

申请号：US13525212

申请日：2012-06-15

Applicant: Hong ZHANG ,  Li Yin ,  Zhe Wang ,  Zhengping Zuo

Inventor： Hong ZHANG ,  Li Yin ,  Zhe Wang ,  Zhengping Zuo

IPC: H04Q5/22 ,  G06F3/041

CPC classification number: G06F3/04886 ,  G08C17/02 ,  G08C23/04 ,  H04N21/42224 ,  H04Q2213/13106

Abstract: Apparatus and methods of a remote control device are provided. The remote control device includes a switch and a power input. The remote control device also includes a touch panel configured to operate in an absence of backlight. The touch panel is configured to receive a first input at a first area of the touch panel and a second input at a second area of the touch panel. The remote control device includes a processing unit configured to provide first control data representing the first input and second control data representing the second input. The first control data can control movement of a cursor on the electronic device. The second control data can identify text corresponding to the second input. The remote control device includes a transmitter configured to provide the control data to the electronic device.

Abstract translation: 提供遥控装置的装置和方法。 遥控装置包括开关和电源输入。 遥控装置还包括配置为在没有背光的情况下操作的触摸面板。 触摸面板被配置为在触摸面板的第一区域处接收第一输入，并且在触摸面板的第二区域处接收第二输入。 遥控装置包括处理单元，其被配置为提供表示第一输入的第一控制数据和表示第二输入的第二控制数据。 第一控制数据可以控制光标在电子设备上的移动。 第二控制数据可以识别对应于第二输入的文本。 遥控装置包括被配置为向电子装置提供控制数据的发射器。

公开(公告)号：US08552162B2

公开(公告)日：2013-10-08

申请号：US12463140

申请日：2009-05-08

Applicant: Guoyou Xu ,  Datong Tang ,  In Jong Kim ,  Ly Tam Phan ,  Yat Sun Or ,  Zhe Wang

Inventor： Guoyou Xu ,  Datong Tang ,  In Jong Kim ,  Ly Tam Phan ,  Yat Sun Or ,  Zhe Wang

IPC: C07H17/08

CPC classification number: C07D417/04 ,  C07D417/14 ,  C07D493/08

Abstract: The present invention relates to processes and intermediates for the preparation of 2-fluoro 6-11 bicyclic erythromycin derivatives. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (X-c):

Abstract translation: 本发明涉及制备2-氟6-11双环红霉素衍生物的方法和中间体。 特别地，本发明涉及制备式（X-c）化合物的方法和中间体：

公开(公告)号：US20130163868A1

公开(公告)日：2013-06-27

申请号：US13579401

申请日：2011-02-11

Applicant: Zhe Wang ,  Jiefu Zhai

Inventor： Zhe Wang ,  Jiefu Zhai

IPC: G06K9/46

CPC classification number: G06T5/009 ,  G06T7/11 ,  G06T2207/10016 ,  G06T2207/20208

Abstract: A method for toning mapping high dynamic range (HDR) video for display in low dynamic range display comprises accessing the HDR video; producing a luminance information for the individual frames; partitioning different consecutive groups of frames into segments responsive to the luminance information; classifying the segments into static luminance segments and transient luminance segments; producing a tone mapping parameter set for the static luminance segments; producing a tone mapping parameter set for at least one of the transient luminance segments responsive to the tone mapping parameter set of an adjacent static luminance segment; and tone mapping the static luminance segments and transient luminance segments according to the respective tone mapping parameter sets.

Abstract translation: 用于色调映射高动态范围（HDR）视频以在低动态范围显示中显示的方法包括访问HDR视频; 产生各个帧的亮度信息; 响应于亮度信息将不同连续的帧组划分成段; 将段分为静态亮度段和瞬态亮度段; 产生用于静态亮度段的色调映射参数集; 响应于相邻静态亮度段的色调映射参数集，产生针对所述瞬态亮度段中的至少一个的色调映射参数集; 以及根据各个色调映射参数组对静态亮度段和瞬态亮度段进行色调映射。

公开(公告)号：US20130141432A1

公开(公告)日：2013-06-06

申请号：US13816522

申请日：2010-08-19

Applicant: Zhe Wang ,  Jiefu Zhai ,  Tao Zhang

Inventor： Zhe Wang ,  Jiefu Zhai ,  Tao Zhang

IPC: G09G5/06

CPC classification number: G09G5/06 ,  G09G3/003 ,  G09G2320/0209 ,  G09G2320/0606 ,  G09G2320/0666 ,  G09G2320/0686 ,  G09G2320/0693 ,  H04N13/324 ,  H04N13/327 ,  H04N13/332

Abstract: A method and system for calibration and compensation of color in a three dimensional display system includes user calibration of individual color channels using a multiplicity of grey screens while viewing with three dimensional glasses. Look-up tables are generated to ease conversion of input pixels to color corrected pixels to pre-distort the color of the pixels being driven by the three dimensional display system. Input pixels are then converted using the look-up tables and color corrected frames are displayed to a user. The pre-distortion effect allows a user to perceive colors in the three dimensional system as intended with the distortions caused by the viewing glasses and other aspects of the three dimensional display system.

Abstract translation: 用于在三维显示系统中校准和补偿颜色的方法和系统包括使用多个灰色屏幕的用户校准各个颜色通道，同时用三维眼镜观看。 生成查找表以简化输入像素到颜色校正像素的转换，以预先变形由三维显示系统驱动的像素的颜色。 然后使用查找表转换输入像素，并且向用户显示颜色校正的帧。 预失真效果允许用户以三维显示系统的观看眼镜和其他方面所引起的失真的方式感知三维系统中的颜色。

公开(公告)号：US08447601B2

公开(公告)日：2013-05-21

申请号：US13325985

申请日：2011-12-14

Applicant: Zhe Wang

Inventor： Zhe Wang

IPC: G10L15/20 ,  G10L21/02

CPC classification number: G10L21/0208 ,  G10L25/84

Abstract: A method and a device for tracking background noise in a communication system are provided. The method includes: calculating a SNR of a current frame according to input audio signals; increasing a frame counter, and calculating tone features and signal steadiness features of the current frame if the SNR of the current frame is not less than a first threshold; determining the possibility of a time window including a noise interval according to the calculated tone feature values and signal steadiness feature values of each frame of the time window when the frame counter is increased to the length of the time window; and extracting noise features in the time window. Existence of background noise is analyzed continuously in a time window, so that background noise that changes frequently.

Abstract translation: 提供了一种用于跟踪通信系统中的背景噪声的方法和装置。 该方法包括：根据输入的音频信号计算当前帧的SNR; 如果当前帧的SNR不小于第一阈值，则增加帧计数器，以及计算当前帧的色调特征和信号稳定特征; 当帧计数器增加到时间窗口的长度时，根据所计算的色调特征值和时间窗口的每个帧的信号稳定特征值，确定包括噪声间隔的时间窗口的可能性; 并在时间窗口中提取噪声特征。 在时间窗口中连续分析背景噪声的存在，从而频繁变化的背景噪声。