公开(公告)号：US20120276596A1

公开(公告)日：2012-11-01

申请号：US13515942

申请日：2010-12-15

Applicant: Jaakko Pere ,  Maria Smolander ,  Harry Boer

Inventor： Jaakko Pere ,  Maria Smolander ,  Harry Boer

IPC: C08B37/06 ,  C09D105/06 ,  C12P19/04

CPC classification number: D21H11/20 ,  C08B37/0045 ,  C08J3/24 ,  C08J2305/06 ,  C08K5/0025 ,  C08K5/053 ,  C08L2205/02 ,  C08L2205/03 ,  C09D105/06 ,  C12P19/04 ,  D21C5/005 ,  D21C9/002 ,  D21H17/005 ,  D21H27/10 ,  C08L5/00 ,  C08L5/06 ,  C08L1/04 ,  C08L1/02 ,  C08L1/286

Abstract: The present invention relates to the fields of biomass technology, and more precisely to applications of packaging, and coating products for food and cosmetics. The present invention relates to a method of modifying a polymeric polysaccharide matrix and to a method of coating a product to impart new properties to the product. The present invention further relates to a modified polymeric polysaccharide matrix, to a product being coated with a modified polymeric polysaccharide matrix and uses thereof.

Abstract translation: 本发明涉及生物质技术领域，更具体地涉及包装用途以及用于食品和化妆品的涂料产品。 本发明涉及一种改性聚合多糖基质的方法和一种涂覆产品以赋予产品新特性的方法。 本发明还涉及一种改性的聚合多糖基质，与被改性聚合多糖基质涂覆的产品及其用途。

公开(公告)号：US20120156296A1

公开(公告)日：2012-06-21

申请号：US13333410

申请日：2011-12-21

Applicant: Trine-Lise Torgersen ,  Jo Klaveness ,  Astrid Hilde Myrset

Inventor： Trine-Lise Torgersen ,  Jo Klaveness ,  Astrid Hilde Myrset

IPC: A61K31/232 ,  A61K9/00 ,  A61K9/28 ,  A61K9/36 ,  A61K9/32 ,  A61K9/40 ,  A61K9/30 ,  A61P3/04 ,  A61P3/00 ,  A61P3/10 ,  A61P3/06 ,  A61P9/10 ,  A61P7/02 ,  A61P29/00 ,  A61K31/724

CPC classification number: C11B5/0092 ,  A23D7/0053 ,  A23D7/04 ,  A23D9/007 ,  A23D9/05 ,  A23L3/3508 ,  A23L33/115 ,  A23L33/12 ,  A23L33/15 ,  A23V2002/00 ,  A61K9/0007 ,  A61K9/0056 ,  A61K9/145 ,  A61K9/146 ,  A61K9/2018 ,  A61K9/4825 ,  A61K35/655 ,  A61K47/6951 ,  C08B15/00 ,  C08B37/0015 ,  C08L1/04 ,  C08L5/16 ,  C11B5/0021 ,  C11B5/0028 ,  C11B5/005 ,  A23V2200/02 ,  A23V2200/214 ,  A23V2250/1882 ,  A23V2250/5112 ,  A23V2250/708 ,  A61K2300/00

Abstract: This invention relates to antioxidants and combinations of antioxidants used to prevent oxidation of pharmaceutical and nutraceutical products in the form of powders, granulates, tablets, emulsions, gels and the like comprising one or more fatty acids and/or fatty acid derivatives and, optionally, at least one carbohydrate carrier alone or together with vitamins, minerals and/or pharmaceuticals. In particular, the invention concerns the use of antioxidants to reduce oxidation of powders, tablets, gels and emulsions comprising high concentrations and high doses of omega-3 fatty acids or derivatives thereof.

Abstract translation: 本发明涉及抗氧化剂和抗氧化剂的组合，其用于防止包含一种或多种脂肪酸和/或脂肪酸衍生物的粉末，颗粒，片剂，乳剂，凝胶等形式的药物和营养产品的氧化， 至少一种碳水化合物载体单独或与维生素，矿物质和/或药物一起。 特别地，本发明涉及使用抗氧化剂来减少包含高浓度和高剂量的ω-3脂肪酸或其衍生物的粉末，片剂，凝胶和乳液的氧化。

公开(公告)号：US20120142787A1

公开(公告)日：2012-06-07

申请号：US12973967

申请日：2010-12-21

Applicant: Helen S. M. LU ,  STEVEN W. SHUEY

Inventor： Helen S. M. LU ,  STEVEN W. SHUEY

IPC: A61K47/36 ,  A61K47/38 ,  C07K14/62 ,  C07H7/02 ,  C07H3/00

CPC classification number: C08B15/02 ,  C08B31/18 ,  C08B37/00 ,  C08B37/0018 ,  C08B37/0021 ,  C08B37/0054 ,  C08B37/0072 ,  C08L1/04 ,  C08L3/10 ,  C08L5/00 ,  C08L5/02 ,  C08L5/08 ,  C08L5/12

Abstract: Novel aldehyde-functionalized polysaccharide compositions containing pendant dialdehyde groups are described that are more stable in aqueous solution than oxidized polysaccharides. The aldehyde-functionalized polysaccharides may be reacted with various amine-containing polymers to form hydrogel tissue adhesives and sealants that may be useful for medical applications such as wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, tissue repair, preventing leakage of fluids such as blood, bile, gastrointestinal fluid and cerebrospinal fluid, ophthalmic procedures, drug delivery, and preventing post-surgical adhesions.

Abstract translation: 描述了含有侧链二醛基团的新型醛官能化多糖组合物，其在水溶液中比氧化多糖更稳定。 醛官能化多糖可以与各种含胺聚合物反应以形成可用于医学应用的水凝胶组织粘合剂和密封剂，例如伤口闭合，补充或替换缝合或缝合在内部外科手术如肠吻合和血管吻合中 ，组织修复，防止流体如血液，胆汁，胃肠道液体和脑脊液的渗漏，眼科手术，药物递送和预防手术后粘连。

公开(公告)号：US20090130287A1

公开(公告)日：2009-05-21

申请号：US12265970

申请日：2008-11-06

Applicant: Domingo C. Tuason ,  Jose Amundarain ,  Gregory R. Krawczyk ,  Edward Selinger ,  William R. Blakemore ,  James J. Modliszewski ,  Joseph Lee ,  Frank Messick

Inventor： Domingo C. Tuason ,  Jose Amundarain ,  Gregory R. Krawczyk ,  Edward Selinger ,  William R. Blakemore ,  James J. Modliszewski ,  Joseph Lee ,  Frank Messick

IPC: A23L1/0534 ,  A23L1/0524 ,  B01J13/00

CPC classification number: A23L1/0534 ,  A01N25/10 ,  A23C9/137 ,  A23G1/56 ,  A23G3/346 ,  A23G2200/06 ,  A23L2/52 ,  A23L19/09 ,  A23L29/256 ,  A23L29/262 ,  A23V2002/00 ,  A61K8/02 ,  A61K8/73 ,  A61K8/731 ,  A61K8/733 ,  A61K9/146 ,  A61K47/36 ,  A61K47/38 ,  A61K2800/412 ,  A61K2800/594 ,  A61Q5/00 ,  A61Q19/00 ,  C08B15/02 ,  C08J3/12 ,  C08J3/128 ,  C08J2301/04 ,  C08J2305/04 ,  C08K3/16 ,  C08L1/02 ,  C08L1/04 ,  C08L5/00 ,  C08L5/04 ,  C08L5/06 ,  C08L2205/02 ,  C08L2666/26 ,  A23V2250/50364 ,  A23V2250/51084 ,  A23V2200/254 ,  A23V2250/50362 ,  A23V2250/50722 ,  A23V2250/5086 ,  A23V2250/1578 ,  A23V2250/5026 ,  A23V2250/5118

Abstract: Ultra-fine microcrystalline cellulose compositions are disclosed which comprise co-attrited microcrystalline cellulose and a hydrocolloid. The compositions have a mean particle size of less than 10 microns. The compositions are prepared by subjecting a high solids mixture of microcrystalline cellulose and a hydrocolloid to high shear forces in the presence of an anti slip agent preferably an aqueous solution of an inorganic salt. The compositions are especially useful in food, pharmaceutical and cosmetic and industrial applications.

Abstract translation: 公开了包含共磨微晶纤维素和水胶体的超细微晶纤维素组合物。 组合物具有小于10微米的平均粒度。 通过在防滑剂，优选无机盐的水溶液存在下，使微晶纤维素和水胶体的高固体混合物经受高剪切力制备组合物。 该组合物特别适用于食品，药物和化妆品及工业应用。

公开(公告)号：US20090054270A1

公开(公告)日：2009-02-26

申请号：US12194986

申请日：2008-08-20

Applicant: Denise L. Williams ,  Michael L. Rambo ,  Peter J. Olney ,  Neil W. Camp ,  Bruce R. Sebree

Inventor： Denise L. Williams ,  Michael L. Rambo ,  Peter J. Olney ,  Neil W. Camp ,  Bruce R. Sebree

IPC: C09K8/10

CPC classification number: C09K8/10 ,  C08K5/06 ,  C08K5/101 ,  C08L1/00 ,  C08L1/02 ,  C08L1/04 ,  C08L1/26 ,  C08L1/28 ,  C08L1/284 ,  C08L1/286 ,  C08L5/00 ,  C08L5/04 ,  C08L2666/26

Abstract: Hydrocolloid gum compositions, methods of forming the same, and products formed therefrom. The composition may comprise a hydrocolloid gum, such as xanthan gum, a cellulose thickener, and a solvent component. The solvent component may comprise a lactate ester and, optionally, an alkylene glycol alkyl ether.

Abstract translation: 水胶体胶组合物，其形成方法和由其形成的产品。 组合物可以包含水胶体胶，例如黄原胶，纤维素增稠剂和溶剂组分。 溶剂组分可以包含乳酸酯和任选的亚烷基二醇烷基醚。

公开(公告)号：US20080181936A1

公开(公告)日：2008-07-31

申请号：US11872072

申请日：2007-10-15

Applicant: Vladimir N. Filatov ,  Vladimir Ryltsev ,  Uri Martinovitz ,  Zidkiyahu Simenhaus

Inventor： Vladimir N. Filatov ,  Vladimir Ryltsev ,  Uri Martinovitz ,  Zidkiyahu Simenhaus

IPC: A61L15/28 ,  A61K31/722 ,  A61K38/17

CPC classification number: A61K9/70 ,  A61F13/00085 ,  A61K31/192 ,  A61K31/198 ,  A61K31/717 ,  A61K33/38 ,  A61L15/28 ,  A61L15/32 ,  A61L15/42 ,  A61L2400/04 ,  C08L1/04 ,  C08L5/08 ,  D10B2509/022

Abstract: A hemostatic textile material to stop bleeding comprising a dialdehyde cellulose (DAC) carrier wherein the degree of oxidation of the dialdehyde cellulose varies from about 1.5% to 12%; and a blood coagulation factor selected from the group consisting of chitosan and gelatin; the blood coagulation factor being chemically immobilized thereon; and further optionally comprising a bacteriolytic agent selected from the group consisting of a lysozyme enzyme, silver nitrate, and chlorhexidine; and further optionally comprising a selected component that prevents hemolysis, the component selected from the group consisting of tranexamic acid or ε-aminocaproic acid chemically immobilized thereon.

Abstract translation: 一种用于止血的止血纺织材料，其包含二醛纤维素（DAC）载体，其中二醛纤维素的氧化度为约1.5％至12％; 和选自壳聚糖和明胶的凝血因子; 血液凝固因子在其上化学固定; 并且还任选地包含选自溶菌酶，硝酸银和氯己定的溶菌剂; 并且进一步任选地包含防止溶血的选择的组分，所述组分选自在其上化学固定的氨甲环酸或ε-氨基己酸。

公开(公告)号：US20070054880A1

公开(公告)日：2007-03-08

申请号：US10911645

申请日：2004-08-05

Applicant: Lowell Saferstein ,  Gonzalo Serafica

Inventor： Lowell Saferstein ,  Gonzalo Serafica

IPC: A61K31/717 ,  C08B1/00

CPC classification number: C08B15/04 ,  A61L15/28 ,  A61L27/20 ,  A61L31/042 ,  C08L1/04

Abstract: This invention relates to a process for preparing bioabsorbable oxidized cellulose comprising combining cellulose material, with nitrogen dioxide and a nonaqueous solvent chosen from the class of perfluorinated tertiary amines. This invention also relates to a method of oxidizing cellulose material comprising introducing a solvent into the vessel, circulating the solvent through the cellulose material, adding nitrogen dioxide to said vessel containing the solvent and cellulose in the required amounts, circulating the solution for 7 to 24 hours while controlling the reaction temperature, and isolating the oxidized material. Preferably, isolation of the oxidized product is followed by first washing the oxidized cellulose material with cold water, then washing the oxidized cellulose material with an aqueous alcohol solution several times, then washing the material with 100% alcohol several times, and finally drying the oxidized material.

Abstract translation: 本发明涉及一种制备生物可吸收氧化纤维素的方法，包括将纤维素材料与二氧化氮和选自全氟化叔胺类的非水溶剂混合。 本发明还涉及一种氧化纤维素材料的方法，包括将溶剂引入容器中，使溶剂循环通过纤维素材料，向含有溶剂的容器和所需量的纤维素中加入二氧化氮，将溶液循环7至24 同时控制反应温度，并分离氧化物质。 优选地，分离氧化产物之后首先用冷水洗涤氧化的纤维素材料，然后用醇水溶液洗涤氧化的纤维素材料几次，然后用100％醇洗涤该物质几次，最后干燥氧化的 材料。

公开(公告)号：US20060084338A1

公开(公告)日：2006-04-20

申请号：US11252120

申请日：2005-10-17

Applicant: Dhanuraj Shetty ,  Sanyog Pendharkar ,  Anne Gorman ,  Simmi Kalirai

Inventor： Dhanuraj Shetty ,  Sanyog Pendharkar ,  Anne Gorman ,  Simmi Kalirai

IPC: B32B5/26

CPC classification number: A61L31/042 ,  A61F2/0063 ,  A61F13/00 ,  A61F2013/00604 ,  A61F2013/00927 ,  A61L15/26 ,  A61L15/28 ,  A61L27/18 ,  A61L27/20 ,  A61L27/48 ,  A61L27/58 ,  A61L31/06 ,  A61L2430/06 ,  A61L2430/10 ,  A61L2430/24 ,  B32B5/022 ,  B32B5/024 ,  B32B5/026 ,  B32B5/06 ,  B32B5/10 ,  B32B5/26 ,  B32B9/04 ,  B32B2250/02 ,  B32B2250/20 ,  B32B2262/0276 ,  B32B2262/04 ,  B32B2262/06 ,  B32B2307/726 ,  B32B2459/00 ,  B32B2535/00 ,  D04H1/435 ,  D04H1/4374 ,  Y10T442/3707 ,  Y10T442/494 ,  C08L67/04 ,  C08L1/00 ,  C08L1/24 ,  C08L1/04

Abstract: The present invention is directed to a multilayered fabric comprising a first absorbable nonwoven fabric and a second absorbable woven or knitted fabric.

Abstract translation: 本发明涉及一种包含第一可吸收无纺布和第二可吸收织造或针织物的多层织物。

公开(公告)号：US20060008505A1

公开(公告)日：2006-01-12

申请号：US11176580

申请日：2005-07-08

Applicant: Gerard Brandon

Inventor： Gerard Brandon

IPC: A61K31/716 ,  A61F2/00

CPC classification number: A61L15/64 ,  A61F13/0233 ,  A61F13/0253 ,  A61F2013/00472 ,  A61K31/716 ,  A61L15/28 ,  A61L15/58 ,  C08L1/02 ,  C08L1/04 ,  C08L5/06

Abstract: A delivery system for a haemostatic material comprises a self adhesive strip of a bioadhesive, especially pectin and a glycerol plasticiser. The haemostatic material may be a microdispersed oxidised cellulose which is dispersed in the strip. The strip is applied to control localised bleeding from surface skin wounds such as shaving nicks or minor cuts. The pectin dissolves in the blood, releasing the haemostatic material to control the bleeding.

Abstract translation: 用于止血材料的递送系统包括生物粘附剂的自粘性带，特别是果胶和甘油增塑剂。 止血材料可以是分散在条带中的微分散的氧化纤维素。 该条应用于控制来自表面皮肤伤口的局部出血，例如剃削切口或微小切口。 果胶溶解在血液中，释放止血材料以控制出血。

公开(公告)号：US20040120993A1

公开(公告)日：2004-06-24

申请号：US10326244

申请日：2002-12-20

Inventor： Guanghui Zhang ,  Sanyog Manohar Pendharkar ,  Jian Xin Guo ,  Dwayne Lee Looney ,  Anne Jessica Gorman

IPC: A61K031/715 ,  A61K031/727 ,  A61L015/00

CPC classification number: A61L27/20 ,  A61L15/28 ,  A61L2400/04 ,  Y10T442/2525 ,  C08L1/02 ,  C08L5/00 ,  C08L1/04

Abstract: The present invention is directed to hemostatic wound dressings containing a fabric made from biocompatible, aldehyde-modified polysaccharide fibers; and a porous, polymeric matrix made from a biocompatible, water-soluble or water-swellable polymer, dispersed at least partially through the fabric, to methods of making such wound dressings and to methods of providing hemostasis to a wound.

Abstract translation: 本发明涉及含有由生物相容的醛修饰的多糖纤维制成的织物的止血伤口敷料; 以及由至少部分地通过织物分散的生物相容的水溶性或水可溶胀聚合物制成的多孔聚合物基质，以及制备这种伤口敷料的方法以及向伤口提供止血的方法。