公开(公告)号：US4005102A

公开(公告)日：1977-01-25

申请号：US605397

申请日：1975-08-18

Applicant: Newell C. Cook ,  Gary C. Davis

Inventor： Newell C. Cook ,  Gary C. Davis

IPC: C07B43/02 ,  C07C201/08 ,  C07C205/06 ,  C07C205/12 ,  C07C205/23 ,  C07C205/38 ,  C07C205/45 ,  C07C205/57 ,  C07D209/48 ,  C07D209/34

CPC classification number: C07B43/02 ,  C07C201/08 ,  C07C317/00 ,  C07C2103/20

Abstract: Nitrated derivatives of aromatic compounds are obtained by contacting the latter, in the presence of methylene chloride as a reaction medium, with concentrated nitric acid in the presence of concentrated sulfuric acid, and thereafter isolating the formed nitro derivatives.

Abstract translation: 芳族化合物的硝化衍生物通过在浓硫酸存在下，在二氯甲烷作为反应介质存在下与浓硝酸接触而获得，然后分离所形成的硝基衍生物。

公开(公告)号：US3984565A

公开(公告)日：1976-10-05

申请号：US541421

申请日：1975-01-16

Applicant: Derek Richard Buckle ,  Harry Smith ,  Barrie Christian Charles Cantello

Inventor： Derek Richard Buckle ,  Harry Smith ,  Barrie Christian Charles Cantello

IPC: C07C205/45 ,  A61K31/24 ,  C07C13/465 ,  C07C67/00 ,  C07C201/00 ,  C07C201/08 ,  C07C205/54 ,  C07D307/88 ,  C07D307/89 ,  A61K31/335

CPC classification number: C07D307/88 ,  C07C205/54 ,  C07D307/89 ,  Y10S514/826

Abstract: A pharmaceutical composition is produced which is useful for treating allergic conditions in humans which comprises an anti-allergenic amount of a compound of the formula: ##SPC1##Or a pharmaceutically acceptable salt or ester thereof, wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and each is hydrogen, alkyl, alkoxy, aryl, aralkyl or halogen or any two of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 taken together, with the carbon atoms to which they are attached, form a phenyl, cyclohexyl or cyclohexenyl ring, in combination with a pharmaceutically acceptable carrier.

Abstract translation: 制备可用于治疗人类过敏症状的药物组合物，其包含抗过敏量的下式化合物：

公开(公告)号：US3957889A

公开(公告)日：1976-05-18

申请号：US574131

申请日：1975-05-02

Applicant: Barton Milligan ,  Donald G. Miller

Inventor： Barton Milligan ,  Donald G. Miller

IPC: C07B61/00 ,  B01J21/00 ,  B01J27/00 ,  C07B43/02 ,  C07C67/00 ,  C07C201/00 ,  C07C201/08 ,  C07C205/06 ,  C07C205/11 ,  C07C205/12 ,  C07C79/10 ,  C07C79/12

CPC classification number: C07C201/08 ,  C07B43/02

Abstract: This invention relates to an improvement in a process for nitrating an aromatic or substituted aromatic compound e.g., toluene or ortho-xylene, by reacting such aromatic or substituted aromatic in the presence of nitric acid. The improvement for enhancing the rate of nitration as well as the selectivity of nitration at the para-position in this process comprises carrying out the nitration reaction in the presence of at least an effective amount of anhydrous calcium sulfate or soluble anhydrite.

公开(公告)号：US3929917A

公开(公告)日：1975-12-30

申请号：US47819074

申请日：1974-06-11

Applicant: AMERICAN CYANAMID CO

Inventor： RAUCH FRANCIS CLYDE ,  FANELLI ANTHONY JOSEPH ,  BLANK GERLINDE METZLER

IPC: C07C201/08 ,  C07C205/06 ,  C07C79/10

CPC classification number: C07C201/08 ,  C07C205/06

Abstract: There is provided a process for mononitrating ortho-xylene by reacting o-xylene with nitrogen tetroxide (N2O4) or nitrogen dioxide (NO2) and an oxygen containing gas, such as oxygen, in the presence of a mercuric salt dissolved in acetic acid to obtain good yields of mononitrated o-xylene having an isomer distribution of at least a 70:30 ratio of 4- to 3- nitro-oxylenes. Such 4-nitro-o-xylene, upon separation from the isomeric mixture, finds utility in the preparation of xylidine derived preemergence herbicides.

Abstract translation: 提供了在溶于乙酸的汞盐存在下使邻二甲苯与四氧化二氮（N 2 O 4）或二氧化氮（NO 2）和含氧气体如氧气反应来使邻二甲苯单硝化的方法，得到 具有至少70:30比例的4-至3-硝基 - 邻二甲苯的异氰酸酯邻二甲苯的良好收率。 当与异构体混合物分离时，这种4-硝基邻二甲苯可用于制备二甲苯胺衍生的芽前除草剂。

公开(公告)号：US3780116A

公开(公告)日：1973-12-18

申请号：US3780116D

申请日：1972-06-15

Applicant: ZAVERCHAND & CO

Inventor： SAHGAL P

IPC: C07C201/08 ,  C07C205/06 ,  C07C79/10

CPC classification number: C07C201/08 ,  C07C205/06

Abstract: A PROCESS AND APPARATUS FOR NITRATION OF AN AROMATIC HYDROCARBON SUCH AS BENZENE OR TOLUENE IN WHICH THE HYDROCARBON IS VAPORIZED AND BUBBLED THROUGH AQUEOUS NITRIC ACID IN A REACTION VESSEL AT A TEMPERATURE WHICH MAY VARY FROM 50 TO 100*C. A MIXTURE OF NITRIC ACID AND NITRATED HYDROCARBON WHICH IS FORMED IS CONTINUOUSLY WITHDRAWN FROM THE REACTION VESSEL AND FED TO A SEPARATOR WHERE THE NITRATED HYDROCARBON IS SEPARATED AND WITHDRAWN AND THE NITRIC ACID IS RETURNED TO THE REACTION VESSEL.

D R A W I N G

公开(公告)号：US3488397A

公开(公告)日：1970-01-06

申请号：US3488397D

申请日：1967-10-19

Applicant: BOFORS AB

Inventor： HAKANSSON CHRISTER LENNART ,  ARVIDSSON ARNE ARVID ,  LOKEN INGAR

IPC: C07C201/08 ,  C07C205/06 ,  C07C79/10

CPC classification number: C07C201/08 ,  C07C205/06

公开(公告)号：US3445529A

公开(公告)日：1969-05-20

申请号：US3445529D

申请日：1967-06-09

Applicant: TEXACO INC

Inventor： SMETANA RICHARD D

IPC: C07C201/02 ,  C07C201/08 ,  C07C203/04 ,  C07C203/08 ,  C07C205/02 ,  C07C205/05 ,  C07C79/02 ,  C07C77/00 ,  C07C77/02

CPC classification number: C07C201/02 ,  C07C201/08 ,  C07C205/02 ,  C07C203/04

公开(公告)号：US3417127A

公开(公告)日：1968-12-17

申请号：US64478367

申请日：1967-06-09

Applicant: TEXACO INC

Inventor： SMETANA RICHARD D ,  HARRY CHAFETZ

IPC: C07B43/02 ,  C07C201/08 ,  C07C205/02 ,  C07C205/05

CPC classification number: C07B43/02 ,  C07C201/08 ,  C07C2601/14 ,  C07C205/05 ,  C07C205/02

公开(公告)号：US3415868A

公开(公告)日：1968-12-10

申请号：US64478467

申请日：1967-06-09

Applicant: TEXACO INC

Inventor： SMETANA RICHARD D ,  HARRY CHAFETZ

IPC: C07B43/02 ,  C07C201/08 ,  C07C205/02 ,  C07C205/05

CPC classification number: C07C201/08 ,  C07B43/02 ,  C07C2601/14 ,  C07C205/02 ,  C07C205/05

公开(公告)号：US3371122A

公开(公告)日：1968-02-27

申请号：US59860266

申请日：1966-12-02

Applicant: DU PONT

Inventor： REINHOLD BETSCHEL

IPC: C07C201/08 ,  C07C205/06

CPC classification number: C07C201/08 ,  C07C205/06