公开(公告)号：US12070269B2

公开(公告)日：2024-08-27

申请号：US17532501

申请日：2021-11-22

Applicant: OPTOS PLC

Inventor： Miguel Angel Preciado ,  Lijo Varughese Chacko

IPC: A61B3/10 ,  G01B9/02091

CPC classification number: A61B3/102 ,  G01B9/02091

Abstract: An optical coherence tomography instrument suitable for imaging a retina is disclosed. In the instrument, an adjustable optical frequency shifter, which can be or include an acousto-optic modulator or electro-optic modulator, is arranged either (i) between a coupler and a reference optical system, (ii) in a reference optical system, (iii) between the coupler and a front-end optical system, or (iv) in a front-end optical system. The optical frequency of reference light or signal light may adjustably be increased or decreased. In operation, a subject is arranged such that its retina is in the focal depth of the front-end optical system. The increase or decrease in the optical frequency of the reference light or the sample light can be adjusted. Thereby, an interferogram representing a depth structure at the retina obtained between returning signal light and returning reference light may be brought to lie within a detection bandwidth of the instrument.

公开(公告)号：US11974810B2

公开(公告)日：2024-05-07

申请号：US17036184

申请日：2020-09-29

Applicant: Optos Plc

Inventor： Daniel Hurst

IPC: A61B3/10 ,  A61B3/02 ,  A61B3/12 ,  A61B3/14 ,  G06T5/00 ,  G06T5/50

CPC classification number: A61B3/12 ,  A61B3/14 ,  G06T5/002 ,  G06T5/50 ,  G06T2207/20221 ,  G06T2207/30041

Abstract: An imaging system for generating an image of a region of an eye, comprising: an ocular imaging device controlled by a control module to acquire, from a first viewpoint, a first ocular image of the region having an image artefact caused by obstruction from imaging of a part of the region by an object, and a second ocular image from a predetermined second viewpoint, which shows at least a portion of the part of the region that was obstructed from imaging during acquisition of the first ocular image; and an image data processing module for combining the first and second ocular images to generate an enhanced ocular image having an image artefact caused by obstruction from imaging by the object which is smaller in relation to the image artefact in the first or second ocular image, or no such image artefact.

公开(公告)号：US11857256B2

公开(公告)日：2024-01-02

申请号：US16721899

申请日：2019-12-19

Applicant: OPTOS PLC

Inventor： Jenny Rice-Jones ,  Gary Young ,  George McGaughay ,  Scott Dalzell ,  Laurie Ibbs ,  Geoff Smith

IPC: A61B3/00 ,  A61B3/10 ,  A61B3/12 ,  G06F3/0354 ,  G06F3/04845 ,  G06F3/0485 ,  G06F3/04883

CPC classification number: A61B3/0033 ,  A61B3/0025 ,  A61B3/0041 ,  A61B3/102 ,  A61B3/1225 ,  G06F3/03547 ,  G06F3/0485 ,  G06F3/04845 ,  G06F3/04883 ,  G06F2203/04808

Abstract: An apparatus, method, computer-readable medium, and computer program product, for designating an OCT scan location to be performed on a retina. The apparatus comprises a display device for displaying an image comprising a background image of the retina and a planning element designating the location; a touch-sensitive input device that generates touch interaction data indicative of touch interaction of a user with the input device; an image manipulation module determines, based on the touch interaction data, a manipulation to be performed on the displayed image, and applies the image manipulation to the image in response to each touch interaction to generate an updated image to display; and a scan location designation module generates data indicative of the location of the OCT scan to be performed, based on a location of the planning element on the background image in at least one updated image.

公开(公告)号：US20230363639A1

公开(公告)日：2023-11-16

申请号：US18197059

申请日：2023-05-13

Applicant: Optos PLC

Inventor： Miguel Angel Preciado

IPC: A61B3/10 ,  A61B5/00

CPC classification number: A61B3/102 ,  A61B5/0066 ,  A61B3/0025

Abstract: A non-confocal point-scan Fourier-domain optical coherence tomography, OCT, imaging system, comprising: a scanning system arranged to perform a two-dimensional point scan of a light beam across an imaging target, and collect light scattered by the imaging target; a light detector arranged to generate a detection signal based on an interference between a reference light and the light collected by the scanning system. The OCT imaging system further comprises hardware arranged to: generate complex volumetric OCT data of the imaging target based on the detection signal, the OCT data including a component which, when the OCT data is processed to generate an enface projection of the OCT data, provides a defocusing and/or distortion in the enface projection; and generate corrected OCT data by executing a correction algorithm which uses phase information in the OCT data to remove at least some of the component from the OCT data.

公开(公告)号：US20230298236A1

公开(公告)日：2023-09-21

申请号：US18108103

申请日：2023-02-10

Applicant: OPTOS PLC

Inventor： Gagarine Yaikhom

IPC: G06T11/60 ,  G16H30/40 ,  G16H50/50 ,  A61B3/10 ,  A61B3/12

CPC classification number: G06T11/60 ,  A61B3/102 ,  A61B3/1241 ,  G16H30/40 ,  G16H50/50 ,  G06T2210/22

Abstract: A computer-implemented method of processing repeat B-scans of an imaged region of a body part, the imaged region including an anatomical feature in a first subregion and vasculature of interest in a second subregion of the imaged region, to generate cropped B-scans for use in generating OCT angiography data which provides a representation of the vasculature of interest, the method comprising processing each B-scan of the repeat B-scans by: selecting a subset of the data elements of the B-scan such that the selected data elements are distributed along a representation of the anatomical feature in the B-scan; using the selected data elements to define a respective subregion of interest in the B-scan, which includes OCT data acquired from the second subregion containing the vasculature of interest; and cropping the B-scan to leave the subregion of interest in the B-scan.

公开(公告)号：US11763490B2

公开(公告)日：2023-09-19

申请号：US16936891

申请日：2020-07-23

Applicant: Optos plc

Inventor： Brendan Hamel-Bissell ,  Benjamin Adam Jacobson ,  Clint Suson ,  Clark Pentico ,  Andre E. Adams ,  Tushar M. Ranchod

IPC: G06T7/80 ,  H04N17/00 ,  G06T5/50 ,  H04N23/56 ,  H04N23/67

CPC classification number: G06T7/80 ,  G06T5/50 ,  H04N17/002 ,  H04N23/56 ,  H04N23/67 ,  G06T2207/20221 ,  G06T2207/30201

Abstract: Method of aligning an imaging device with respect to an object, the imaging device comprising two or more optical channels, is disclosed. The method may include aiming the two or more optical channels at corresponding overlapping zones of the object such that the two or more optical channels are oriented at different angles relative to each other and off-axis relative to a central axis of the imaging device. The method may additionally include guiding or focusing the imaging device relative to the object using composite images created by combining separate images from the two or more optical channels.

公开(公告)号：US11751765B2

公开(公告)日：2023-09-12

申请号：US17036201

申请日：2020-09-29

Applicant: Optos Plc

Inventor： Miguel Angel Preciado

IPC: A61B3/15 ,  G02B26/02 ,  G02B26/08 ,  G02B26/10 ,  G02F1/137 ,  A61B90/30

CPC classification number: A61B3/156 ,  G02B26/02 ,  G02B26/0816 ,  G02B26/101 ,  G02F1/137 ,  A61B2090/306

Abstract: An ophthalmic device for imaging an eye, wherein a scanning element scans a first portion of light beam across a region of an eye via a light guiding component and a second portion of the light beam is reflected back by the light guiding component. The ophthalmic device further comprises: a light detector to detect light reflected from eye and guided to the light detector by the light guiding component; and a dynamic amplitude mask which receives the light reflected from the eye and the light reflected back by the light guiding component, and has an unmasked portion to allow light reflected from the eye to reach the light detector, and a masked portion whose spatial distribution varies with a scan angle such that the masked portion prevents light reflected back by the light guiding component from reaching the light detector during the scan.

公开(公告)号：US11635552B2

公开(公告)日：2023-04-25

申请号：US16636999

申请日：2017-08-14

Applicant: Optos PLC

Inventor： Alan Anderson ,  Praveen Ashok ,  Hiroshi Kasai ,  Alistair Gorman

IPC: G02B3/14 ,  G02B26/10

Abstract: An optical system comprising: an optical element having an optical property responsive to an applied signal, a variation of the optical property with the signal exhibiting hysteresis in a first range of values and no hysteresis in a second range of values of the signal; a memory storing data representing a hysteresis curve which indicates the variation of the optical property with increasing and decreasing values of the signal; and a controller which continuously controls the optical property by: generating, based on the stored data, a cyclic signal having a discontinuity in each cycle of the cyclic signal, and setting the discontinuity size in each cycle based on the stored data such that a part of the variation of the optical property with the cyclic signal coincides with a part of the variation represented by the stored data; and applying the cyclic signal to the optical element.

公开(公告)号：US20220304566A1

公开(公告)日：2022-09-29

申请号：US17702119

申请日：2022-03-23

Applicant: OPTOS PLC

Inventor： Alan Duncan Fleming

IPC: A61B3/00 ,  G06T7/00 ,  G06T7/33 ,  G06T11/00 ,  G06T7/50 ,  A61B3/12 ,  A61B3/10

Abstract: There is provided a method of processing image data defining a fundus image of a retina to include supplementary information on a designated feature in the fundus image, comprising: designating (S10) a feature in the fundus image; receiving (S20) OCT data of a C-scan of the retina; selecting (S30) a subset of the OCT data representing a volumetric image of a part of the retina at a location on the retina corresponding to a location of the designated feature in the fundus image; processing (S40) the selected subset to generate, as the supplementary information, supplementary image data indicative of a variation, along a depth direction of the retina, of a measured reflectance of the eye in the selected subset; and combining (S50) the image data with the supplementary image data, such that an image defined by the combined data provides an indication of the variation at the designated feature.

公开(公告)号：US20220261989A1

公开(公告)日：2022-08-18

申请号：US17631275

申请日：2020-07-29

Applicant: NIKON CORPORATION ,  Optos plc

Inventor： Devin SOARES ,  Branden COLEMAN ,  Bradley YATES ,  Naoyuki KAWACHI

IPC: G06T7/00 ,  A61B3/14 ,  A61B3/12 ,  A61B3/10 ,  G16H50/20 ,  G16H30/20

Abstract: An information processing system comprises: an image acquisition device acquiring subject eye image data of a patient; and a first information processing device communicating with the image acquisition device and storing the image data, the image acquisition device transmits, to the first information processing device, the image data and first transmission data including additional information used to identify an image diagnosis device performing image diagnosis on the image data, the first information processing device: stores the image data when receiving the first transmission data from the image acquisition device; identifies, based on the additional information, a first image diagnosis device performing a first image diagnosis on the image data and/or a second image diagnosis device performing a second image diagnosis differing from the first image diagnosis on the image data; and transmits second transmission data including the image data to the identified image diagnosis device.