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公开(公告)号:US11541235B2
公开(公告)日:2023-01-03
申请号:US15688418
申请日:2017-08-28
Applicant: SPR THERAPEUTICS, INC.
Inventor: Joseph W. Boggs , Amorn Wongsarnpigoon , Matthew G. deBock , Nathan Crosby
Abstract: Device/system that provides pain relief by delivering stimulation that neither generates action potentials nor completely blocks neural transmission (in the peripheral nerve). The present teachings provide relief by modulating release of neurotransmitters in peripheral nerves to cause neuromodulation at the level of the peripheral nerve (modulation of neural signals in the peripheral nerve). The present teachings provide relief by modulating release of neurotransmitters in peripheral nerves to cause neuromodulation at the level of the peripheral nerve (modulation of neural signals in the peripheral nerve) to alter the frequency of physiologically generated neural transmission.
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公开(公告)号:US20220016432A1
公开(公告)日:2022-01-20
申请号:US17492091
申请日:2021-10-01
Applicant: SPR Therapeutics, Inc.
Inventor: Joseph W. Boggs , Amorn Wongsarnpigoon , Matthew G. deBock , Meredith J. McGee , Devin Sell , Robert B. Strother
Abstract: An introducing device for locating a tissue region and deploying an electrode is shown and described. The introducing device may include an outer sheath. An inner sheath may be disposed within the outer sheath. The inner sheath may be configured to engage an implantable electrode. In an example, the inner sheath may comprise a stimulation probe having an uninsulated portion at or near a distal end of the delivery sheath. The outer sheath may be coupled to a power source or stimulation signal generating circuitry at a proximal end. A clinician may control application of the stimulation signal to a tissue region via the outer sheath.
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公开(公告)号:US20210386995A1
公开(公告)日:2021-12-16
申请号:US17458664
申请日:2021-08-27
Applicant: SPR Therapeutics, Inc.
Inventor: Joseph W. Boggs , Amorn Wongsarnpigoon , Matthew G. deBock , Meredith J. McGee , Devin Sell , Robert B. Strother
Abstract: An introducing device for locating a tissue region and deploying an electrode is shown and described. The introducing device may include an outer sheath. An inner sheath may be disposed within the outer sheath. The inner sheath may be configured to engage an implantable electrode. In an example, the inner sheath may comprise a stimulation probe having an uninsulated portion at or near a distal end of the delivery sheath. The outer sheath may be coupled to a power source or stimulation signal generating circuitry at a proximal end. A clinician may control application of the stimulation signal to a tissue region via the outer sheath.
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公开(公告)号:USD934438S1
公开(公告)日:2021-10-26
申请号:US29655077
申请日:2018-06-29
Applicant: SPR Therapeutics, Inc.
Designer: Matthew G. deBock , Joseph W. Boggs, II , Devin Sell , Bradley A. Lewis
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公开(公告)号:US20210290948A1
公开(公告)日:2021-09-23
申请号:US17338754
申请日:2021-06-04
Applicant: SPR THERAPEUTICS, INC.
Inventor: Joseph W. Boggs , Rosemary H. Zang
Abstract: Systems and methods are provided for applying electrical stimulation to a body by an electrode spaced from a target nerve of passage. It has been discovered that pain felt, or perceived to be felt, in a given region of the body can be treated by stimulating muscle close to a “nerve of passage” in a region that is superior (i.e., cranial or upstream toward the spinal column) to the region where pain is felt, such as in a case of post-amputation residual limb pain, or purportedly felt in the case of post-amputation phantom limb pain.
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公开(公告)号:US10981005B2
公开(公告)日:2021-04-20
申请号:US15822768
申请日:2017-11-27
Applicant: SPR Therapeutics, Inc.
Inventor: Joseph W. Boggs, II , Robert B. Strother , Kathryn W. Stager , Jonathan L. Sakai , Amorn Wongsarnpigoon , Matthew deBock , Devin Sell , Meredith McGee
Abstract: Neurostimulation assemblies, systems, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles and/or nerves inside the body and stimulus generators and/or recording instruments mounted on the surface of the skin or carried outside the body. The assembly affords maximum patient mobility and comfort through differentiated components having minimal profiles and connected by way of detachable and adjustable connections.
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57.
公开(公告)号:US20200282214A1
公开(公告)日:2020-09-10
申请号:US16881442
申请日:2020-05-22
Applicant: SPR THERAPEUTICS, INC.
Inventor: Joseph W. Boggs, II
IPC: A61N1/36
Abstract: It has been discovered that pain felt in a given region of the body can be treated, not by motor point stimulation of muscle in the local region where pain is felt, but by stimulating muscle spaced from a “nerve of passage” in a region that is superior (i.e., cranial or upstream toward the spinal column) to the region where pain is felt. Spinal nerves such as the intercostal nerves or nerves passing through a nerve plexus, which comprise trunks that divide by divisions and/or cords into branches, comprise “nerves of passage.”
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公开(公告)号:US20190247652A1
公开(公告)日:2019-08-15
申请号:US16391362
申请日:2019-04-23
Applicant: SPR Therapeutics, Inc.
Inventor: Joseph W. Boggs, II , Maria E. Bennett , Amorn Wongsarnpigoon , John Chae , Warren M. Grill , Kathryn Stager , Rosemary Zang
CPC classification number: A61N1/36021 , A61B17/3468 , A61N1/0502 , A61N1/0558 , A61N1/36017 , A61N1/36071
Abstract: It has been discovered that pain felt in a given region of the body can be treated by stimulating a peripheral nerve at a therapeutically effective distance from the region where pain is felt to generate a comfortable sensation (i.e., paresthesia) overlapping the regions of pain. A method has been developed to reduce pain in a painful region following limb joint replacement by stimulating a peripheral nerve innervating the painful region with an electrode inserted into tissue and spaced from the peripheral nerve. This method may be used to help alleviate postoperative pain in patients following total knee arthroplasty surgery or other limb joint replacement surgeries.
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公开(公告)号:US20180133479A1
公开(公告)日:2018-05-17
申请号:US15854206
申请日:2017-12-26
Applicant: SPR Therapeutics, Inc.
Inventor: Maria E. Bennett , Joseph W. Boggs , Warren M. Grill , John Chae
IPC: A61N1/36
Abstract: Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
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公开(公告)号:USD1063850S1
公开(公告)日:2025-02-25
申请号:US29851121
申请日:2022-08-25
Applicant: SPR Therapeutics, Inc.
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