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公开(公告)号:US20220273728A1
公开(公告)日:2022-09-01
申请号:US17740126
申请日:2022-05-09
Applicant: UNIVERSITY OF ROCHESTER
Inventor: Steven GOLDMAN , Fraser J. SIM
IPC: A61K35/30 , C12N5/079 , C12N5/0797 , G01N33/50 , C07K14/705 , C12N9/12
Abstract: The disclosure relates to oligodendrocyte-biased glial progenitor cells and methods of making, isolating, and using such cells.
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公开(公告)号:US20220266582A1
公开(公告)日:2022-08-25
申请号:US17678222
申请日:2022-02-23
Applicant: The University of Rochester
Inventor: Mitchell Anthamatten , Alexander A. Shestopalov
IPC: B32B37/00
Abstract: Describes are methods of contacting printing with a shape-memory stamp. For example, disclosed herein are methods of patterning thin films using shape memory contact printing.
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公开(公告)号:US20220221339A1
公开(公告)日:2022-07-14
申请号:US17603487
申请日:2020-04-03
Applicant: University of Rochester
Inventor: Changsik Yoon , Jannick P. Rolland-Thompson , Aaron Bauer
IPC: G01J3/18 , G01B9/02091 , G01J3/02
Abstract: A detector system for Fourier spectroscopy such as a spectral domain optical coherence tomography instrument includes a diffractive optic for diffracting the interfering light into angularly dispersed wavenumbers, a prism for reduces a nonlinear angular dispersion among the wavenumbers, and a focusing optic for converting the angularly dispersed wavenumbers from the prism into spatially distributed wavenumbers along a detector having an array of pixels. A field lens between the focusing optic and the detector has a freeform surface for more evenly distributing the wavenumbers along the array of pixels.
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公开(公告)号:US11378466B2
公开(公告)日:2022-07-05
申请号:US16787681
申请日:2020-02-11
Applicant: University of Rochester
Inventor: Abdelrahman G. Qoutb , Eby G. Friedman
Abstract: A hybrid integrated thermal sensor device includes a magnetic tunnel junction (MTJ) device electrically coupled in series with at least one CMOS transistor and disposed between a voltage rail terminal and a ground terminal. An output terminal is electrically coupled to a drain of the at least one CMOS transistor. The MTJ operates in an anti-parallel state and the output terminal provides a voltage indicative of a temperature of the MTJ device based on an MTJ antiparallel resistance. A distributed sensor network for real-time thermal mapping of an integrated circuit (IC) is also described.
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公开(公告)号:US20220129654A1
公开(公告)日:2022-04-28
申请号:US17505081
申请日:2021-10-19
Applicant: University of Rochester
Inventor: Gaurav SHARMA
Abstract: A dual-modulated QR code (DMQR code) is in the format of a conventional QR code but uses elongated markers instead of black squares in the code modules. The positions of the markers within the DMQR code represent a nonconfidential primary message, and the orientations of the markers within the modules of the DMQR code represent a confidential secondary message.
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公开(公告)号:US20220125300A1
公开(公告)日:2022-04-28
申请号:US17568685
申请日:2022-01-04
Applicant: University of Rochester
Inventor: James M. Zavislan , Aizhong Zhang
IPC: A61B3/10
Abstract: The present disclosure provides systems and methods for characterizing thin films, such as, for example, diagnosis of dry eye syndrome, thin-film optical metrology testing, etc. The present disclosure may be embodied as a tearscope, which is sometimes referred to herein as a Macroscopic Imaging Ellipsometer (MIE) because it may be considered to be an imaging ellipsometer with, for example, a field-of-view on the order of tens of millimeters or more (i.e., macroscopic), compared with conventional imaging ellipsometers, which usually employ microscope objectives and have fields-of-view of up to several hundred microns.
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公开(公告)号:US20220096863A1
公开(公告)日:2022-03-31
申请号:US17487863
申请日:2021-09-28
Applicant: UNIVERSITY OF ROCHESTER
Inventor: Michael J. Hasselberg , David John Mitten , Kostantinos Vasalos , Wendy Cross
Abstract: An individualized therapy session can be delivered to a patient using a virtual reality headset and system. In one example, the system can include an accelerometer and a processor. The processor can receive data detected by the accelerometer. The data can include head position data and head movement data. The processor can then determine a view direction of a user of the VR device using the head position data, determine a heart rate of the user by using the view direction of the user to process the head movement data, and output the heart rate of the user to a remote device. The processor can receive, from the remote device, a command to adjust a VR session presented by the VR device to the user. Based on the command, the processor can adjust one or more parameters of the VR session presented by the VR device.
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公开(公告)号:US20220090088A1
公开(公告)日:2022-03-24
申请号:US17422885
申请日:2020-01-14
Applicant: University of Rochester
Inventor: Douglas Matthew Anderson
IPC: C12N15/63 , C12N15/113 , C12N15/62 , C12N9/22
Abstract: The present invention provides proteins, nucleic acids, systems and methods for visualizing or modulating RNA.
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59.
公开(公告)号:US20210363509A1
公开(公告)日:2021-11-25
申请号:US17287184
申请日:2019-10-22
Applicant: UNIVERSITY OF ROCHESTER
Inventor: Douglas Matthew Anderson
Abstract: The present invention provides proteins, nucleic acids, systems and methods for editing genomic material.
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公开(公告)号:US20210330599A1
公开(公告)日:2021-10-28
申请号:US16322636
申请日:2017-08-01
Inventor: Danielle BENOIT , Hyun KOO
IPC: A61K9/51 , A61K9/50 , A61K31/045 , A61K31/353 , A61K33/16 , A61K31/505 , A61K31/155 , A61K38/47 , A61K38/44 , A61K31/352 , A61K33/22 , A61K33/18 , A61P1/02 , A61P31/04 , A61K9/00 , A61K45/06 , A61K47/69
Abstract: The present invention relates to compositions and methods to treat and/or prevent biofilms and biofilm related diseases. The invention comprises a nanoparticle carrier (NPC) and at least one therapeutic agent therein. The NPC binds within biofilm and to surfaces at risk for biofilm formation and accumulation while providing local, sustained, enhanced and controlled delivery of the therapeutic agent, when triggered for release. In one embodiment, the NPC comprises pH-responsive elements that allows for specific delivery of the therapeutic agent when the local environment dictates that the agent should be delivered precisely when it is most needed.
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