公开(公告)号：US09168094B2

公开(公告)日：2015-10-27

申请号：US13844677

申请日：2013-03-15

Applicant: MC10, Inc.

Inventor： Stephen P. Lee ,  Clifford Liu ,  Roozbeh Ghaffari ,  John Work ,  Fernando Quivira ,  Lauren E. Klinker ,  Yung-Yu Hsu

IPC: A61B18/18 ,  A61B18/02 ,  A61B18/14 ,  A61B19/00 ,  A61N7/02 ,  A61B18/22 ,  A61B18/00 ,  A61N1/05 ,  A61N1/36

CPC classification number: A61B18/1492 ,  A61B18/02 ,  A61B18/06 ,  A61B18/18 ,  A61B18/1815 ,  A61B18/22 ,  A61B90/30 ,  A61B2018/00041 ,  A61B2018/00178 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00375 ,  A61B2018/00386 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00541 ,  A61B2018/00577 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00791 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00863 ,  A61B2018/0212 ,  A61B2018/1861 ,  A61B2090/065 ,  A61N1/0551 ,  A61N1/36017 ,  A61N1/36117 ,  A61N7/02

Abstract: Devices and methods are provided for performing an ablation procedure on tissue with flow monitoring using flow sensors. The devices include a catheter, and at least one flow sensor disposed on the catheter, and a component for applying the ablation procedure. An assessment module provides an indication of the efficacy of the ablation procedure based on the flow measurement from the flow sensor.

Abstract translation: 提供了设备和方法，用于使用流量传感器对具有流量监测的组织进行消融程序。 装置包括导管，以及设置在导管上的至少一个流量传感器和用于施加消融程序的部件。 评估模块基于来自流量传感器的流量测量提供消融程序的功效的指示。

公开(公告)号：US09012784B2

公开(公告)日：2015-04-21

申请号：US13767262

申请日：2013-02-14

Applicant: MC10, Inc.

Inventor： William J. Arora ,  Roozbeh Ghaffari

IPC: H05K1/00 ,  H05K1/02 ,  H01L23/00 ,  H01L23/528 ,  H01L23/52 ,  A61F2/958

CPC classification number: H05K1/0283 ,  A61F2/958 ,  H01L23/3121 ,  H01L23/4985 ,  H01L23/52 ,  H01L23/528 ,  H01L23/564 ,  H01L25/16 ,  H01L2924/0002 ,  H05K1/00 ,  H05K1/189 ,  H05K3/326 ,  H05K2201/09263 ,  H05K2201/10106 ,  Y10T29/4913 ,  Y10T29/49155 ,  Y10T29/49204 ,  H01L2924/00

Abstract: In embodiments, the present invention may attach at least two isolated electronic components to an elastomeric substrate, and arrange an electrical interconnection between the components in a boustrophedonic pattern interconnecting the two isolated electronic components with the electrical interconnection. The elastomeric substrate may then be stretched such that the components separate relative to one another, where the electrical interconnection maintains substantially identical electrical performance characteristics during stretching, and where the stretching may extend the separation distance between the electrical components to many times that of the unstretched distance.

Abstract translation: 在实施例中，本发明可以将至少两个隔离的电子部件连接到弹性体基板上，并且以将两个隔离的电子部件与电互连互连的连接方式布置在组件之间的电互连。 然后弹性体基底可以被拉伸，使得部件相对于彼此分离，其中电互连在拉伸期间保持基本上相同的电性能特征，并且其中拉伸可以将电气部件之间的间隔距离延伸到未拉伸的许多倍 距离。

公开(公告)号：US20140012242A1

公开(公告)日：2014-01-09

申请号：US13844677

申请日：2013-03-15

Applicant: MC10, Inc.

Inventor： Stephen P. LEE ,  Clifford Liu ,  Roozbeh Ghaffari ,  John Work ,  Fernando Quivira ,  Lauren Klinker ,  Yung-Yu Hsu

IPC: A61B18/18 ,  A61B18/02

CPC classification number: A61B18/1492 ,  A61B18/02 ,  A61B18/06 ,  A61B18/18 ,  A61B18/1815 ,  A61B18/22 ,  A61B90/30 ,  A61B2018/00041 ,  A61B2018/00178 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00375 ,  A61B2018/00386 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00541 ,  A61B2018/00577 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00791 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00863 ,  A61B2018/0212 ,  A61B2018/1861 ,  A61B2090/065 ,  A61N1/0551 ,  A61N1/36017 ,  A61N1/36117 ,  A61N7/02

Abstract: Devices and methods are provided for performing an ablation procedure on tissue with flow monitoring using flow sensors. The devices include a catheter, and at least one flow sensor disposed on the catheter, and a component for applying the ablation procedure. An assessment module provides an indication of the efficacy of the ablation procedure based on the flow measurement from the flow sensor.

Abstract translation: 提供了设备和方法，用于使用流量传感器对具有流量监测的组织进行消融程序。 装置包括导管，以及设置在导管上的至少一个流量传感器和用于施加消融程序的部件。 评估模块基于来自流量传感器的流量测量提供消融程序的功效的指示。

公开(公告)号：US10653332B2

公开(公告)日：2020-05-19

申请号：US15208444

申请日：2016-07-12

Applicant: MC10, Inc.

Inventor： Bryan McGrane ,  Milan Raj ,  PingHung Wei ,  Briana Morey ,  Roozbeh Ghaffari ,  Monica Lin ,  Jeffrey Model ,  Xianyan Wang ,  Bryan Keen ,  Stephen Lee

IPC: H05K1/18 ,  H05K1/02 ,  A61B5/0496 ,  A61B5/00 ,  A61B5/0476 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/0478 ,  A61B5/0408 ,  A61B5/01 ,  A61B5/0402 ,  A61B5/053

Abstract: A device includes a flexible printed circuit board and one or more conductive stiffeners. The conductive stiffeners include a conductive surface that can be electrically connected to contact pads on the flexible printed circuit board. The wearable device can further include an adhesive layer or an encapsulation layer. The adhesive layer and the encapsulation layer can include conductive portions surrounded by non-conductive portions. The conductive portions can be aligned with the conductive stiffeners and together transmit electrical energy to the contact pads of the flexible printed circuit board.

公开(公告)号：US10467926B2

公开(公告)日：2019-11-05

申请号：US15023556

申请日：2014-10-07

Applicant: MC10, Inc.

Inventor： Roozbeh Ghaffari ,  Isaiah Kacyvenski ,  Conor Rafferty ,  Milan Raj ,  Melissa Ceruolo ,  Yung-Yu Hsu ,  Bryan Keen ,  Briana Morey ,  Brian Reilly ,  Ping-Hung Wei

IPC: G09B19/00 ,  A61B5/0488 ,  A61B5/11 ,  G01P7/00 ,  A61B5/00 ,  H04W4/38 ,  H04W4/80 ,  G16H50/20 ,  G16H20/30 ,  H04W80/00

Abstract: Conformal sensor systems and devices are used for sensing and analysis of data indicative of body motion, e.g., for such applications as training and/or clinical purposes. Flexible electronics technology can be implemented as conformal sensors for sensing or measuring motion (including body motion and/or muscle activity), heart rate, electrical activity, and/or body temperature for such applications as medical diagnosis, medical treatment, physical activity, physical therapy and/or clinical purposes. The conformal sensors can be used for detecting and quantifying impact, and can be used for central nervous system disease monitoring.

公开(公告)号：US10383219B2

公开(公告)日：2019-08-13

申请号：US15850129

申请日：2017-12-21

Applicant: MC10, Inc.

Inventor： William J. Arora ,  Roozbeh Ghaffari

IPC: H05K1/18 ,  H05K1/02 ,  H05K1/00 ,  H01L23/498 ,  H01L23/52 ,  H01L23/528 ,  H01L23/00 ,  H05K3/32 ,  H01L23/31 ,  H01L25/16 ,  A61F2/958

Abstract: In embodiments, the present invention may attach at least two isolated electronic components to an elastomeric substrate, and arrange an electrical interconnection between the components in a boustrophedonic pattern interconnecting the two isolated electronic components with the electrical interconnection. The elastomeric substrate may then be stretched such that the components separate relative to one another, where the electrical interconnection maintains substantially identical electrical performance characteristics during stretching, and where the stretching may extend the separation distance between the electrical components to many times that of the unstretched distance.

公开(公告)号：US10325951B2

公开(公告)日：2019-06-18

申请号：US15620181

申请日：2017-06-12

Applicant: MC10, Inc.

Inventor： Bassel de Graff ,  Gilman Callsen ,  William J. Arora ,  Roozbeh Ghaffari

IPC: H01L27/146 ,  A61B1/04 ,  A61B5/145 ,  A61B5/01

Abstract: System, devices and methods are presented that provide an imaging array fabrication process method, comprising fabricating an array of semiconductor imaging elements, interconnecting the elements with stretchable interconnections, and transfer printing the array with a pre-strained elastomeric stamp to a secondary non-planar surface.

公开(公告)号：US20180302980A1

公开(公告)日：2018-10-18

申请号：US15850129

申请日：2017-12-21

Applicant: MC10, Inc.

Inventor： William J. Arora ,  Roozbeh Ghaffari

IPC: H05K1/02 ,  H05K1/00 ,  H01L23/52 ,  H01L25/16 ,  H01L23/31 ,  H01L23/528 ,  H05K1/18 ,  H01L23/00 ,  H01L23/498

CPC classification number: H05K1/0283 ,  A61F2/958 ,  H01L23/3121 ,  H01L23/4985 ,  H01L23/52 ,  H01L23/528 ,  H01L23/564 ,  H01L25/16 ,  H01L2924/0002 ,  H05K1/00 ,  H05K1/189 ,  H05K3/326 ,  H05K2201/09263 ,  H05K2201/10106 ,  Y10T29/4913 ,  Y10T29/49155 ,  Y10T29/49204 ,  H01L2924/00

Abstract: In embodiments, the present invention may attach at least two isolated electronic components to an elastomeric substrate, and arrange an electrical interconnection between the components in a boustrophedonic pattern interconnecting the two isolated electronic components with the electrical interconnection. The elastomeric substrate may then be stretched such that the components separate relative to one another, where the electrical interconnection maintains substantially identical electrical performance characteristics during stretching, and where the stretching may extend the separation distance between the electrical components to many times that of the un-stretched distance.

公开(公告)号：US20180076336A1

公开(公告)日：2018-03-15

申请号：US15498941

申请日：2017-04-27

Applicant: MC10, Inc.

Inventor： Bassel De Graff ,  Roozbeh Ghaffari ,  William J. Arora

IPC: H01L29/82

CPC classification number: H01L27/14692 ,  A61B1/05 ,  A61B5/0024 ,  A61B5/01 ,  A61B5/03 ,  A61B5/04087 ,  A61B5/053 ,  A61B5/6821 ,  A61B5/6833 ,  A61B5/6847 ,  A61B5/6869 ,  A61B8/12 ,  A61B18/1492 ,  A61B18/1815 ,  A61B18/20 ,  A61B18/24 ,  A61B2018/0016 ,  A61B2018/0022 ,  A61B2018/00339 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/0212 ,  A61B2562/164 ,  A61B2562/166 ,  A61N7/022 ,  H01L27/14618 ,  H01L27/14632 ,  H01L27/14645 ,  H01L27/14687 ,  H01L2924/0002 ,  H01L2924/1433 ,  H01L2924/19041 ,  H01L2924/19042 ,  H01L2924/19043 ,  H01L2924/30105 ,  H01L2924/00

Abstract: System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities. The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a the brain, or the surface of the heart. Such direct, conformal contact increases accuracy of measurement and delivery of therapy. Further, the invention enables the incorporation of both sensing and therapeutic devices on the same substrate allowing for faster treatment of diseased tissue and fewer devices to perform the same procedure.

公开(公告)号：US20170340236A1

公开(公告)日：2017-11-30

申请号：US15661172

申请日：2017-07-27

Applicant: MC10, Inc.

Inventor： Roozbeh Ghaffari ,  Yung-Yu Hsu

IPC: A61B5/05 ,  A61B5/053 ,  A61B5/00 ,  A61B5/042 ,  A61B18/02 ,  A61N7/00 ,  A61B18/24 ,  A61B18/14 ,  A61B90/00 ,  A61M25/10 ,  A61B18/00

CPC classification number: A61B5/05 ,  A61B5/0422 ,  A61B5/0538 ,  A61B5/6853 ,  A61B5/6858 ,  A61B5/6885 ,  A61B18/1492 ,  A61B18/24 ,  A61B2018/0022 ,  A61B2018/00285 ,  A61B2018/00345 ,  A61B2018/00375 ,  A61B2018/00577 ,  A61B2018/0212 ,  A61B2090/064 ,  A61B2090/065 ,  A61B2562/046 ,  A61B2562/125 ,  A61B2562/222 ,  A61M25/10187 ,  A61M25/10188 ,  A61M2025/1093 ,  A61N2007/0043 ,  Y10T29/49826

Abstract: An apparatus for medical diagnosis and/or treatment is provides. The apparatus includes a flexible substrate forming an inflatable body and a plurality of force sensing elements disposed on the flexible substrate. The plurality of force sensing elements are disposed about the inflatable body such that the force sensing elements are disposed at areas of minimal curvature of the inflatable body in a deflated state.