公开(公告)号：US20110118302A1

公开(公告)日：2011-05-19

申请号：US12836035

申请日：2010-07-14

Applicant: Roger Smith ,  Stephen J. O'Connor ,  Philip Coish ,  Derek Lowe ,  Roger B. Clark ,  Jeffrey Stebbins ,  Ann-Marie Campbell ,  Christiana Akuche ,  Tatiana Shelekhin

Inventor： Roger Smith ,  Stephen J. O'Connor ,  Philip Coish ,  Derek Lowe ,  Roger B. Clark ,  Jeffrey Stebbins ,  Ann-Marie Campbell ,  Christiana Akuche ,  Tatiana Shelekhin

IPC: A61K31/437 ,  A61K31/428 ,  A61P3/04 ,  A61P3/10 ,  A61P3/00 ,  A61P3/08 ,  A61P9/10 ,  A61P9/00 ,  A61P9/12

CPC classification number: C07D235/30 ,  C07D263/58 ,  C07D277/82 ,  C07D513/04

Abstract: This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.

Abstract translation: 本发明涉及某些联苯-4-基羰基氨基酸化合物，组合物和治疗或预防肥胖症及相关疾病的方法。

公开(公告)号：US20100160371A1

公开(公告)日：2010-06-24

申请号：US12619913

申请日：2009-11-17

Applicant: Gerald RANGES ,  William Scott ,  Michael Bombara ,  Deborah Rauner ,  Aniko Redman ,  Roger Smith ,  Holger Paulsen ,  David Gunn ,  Jinshan Chen ,  Joel Renick

Inventor： Gerald RANGES ,  William Scott ,  Michael Bombara ,  Deborah Rauner ,  Aniko Redman ,  Roger Smith ,  Holger Paulsen ,  David Gunn ,  Jinshan Chen ,  Joel Renick

IPC: A61K31/381 ,  A61K31/341 ,  A61K31/40 ,  A61K31/433 ,  A61K31/47 ,  A61K31/404 ,  A61P29/00 ,  A61P37/00 ,  A61P19/10 ,  A61P11/06

CPC classification number: A61K31/4709 ,  A61K31/341 ,  A61K31/381 ,  A61K31/40 ,  A61K31/4025 ,  A61K31/433 ,  Y02A50/401 ,  Y02A50/411 ,  Y02A50/414

Abstract: This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical compositions for use in such therapy.

Abstract translation: 本发明涉及一组芳基脲在治疗癌症以外的细胞因子介导的疾病和除了癌症以外的蛋白水解酶介导的疾病以及用于这种治疗的药物组合物中的用途。

公开(公告)号：US20100150863A1

公开(公告)日：2010-06-17

申请号：US12520618

申请日：2007-12-20

Applicant: Roger Smith ,  Dhanapalan Nagarathnam

Inventor： Roger Smith ,  Dhanapalan Nagarathnam

IPC: A61K38/20 ,  C07D401/12 ,  A61K31/4439 ,  A61P35/00 ,  A61P35/02 ,  A61K31/4375 ,  A61K38/21 ,  A61K39/395 ,  A61K31/566

CPC classification number: C07D401/12

Abstract: The compound 4-{4-[({3-tert-Butyl-1-[3-(hydroxymethyl)phenyl]-1H-pyrazol-5-yl}-carbamoyl)amino]-3-chlorohenoxy}-N-methylpyridine-2-carboxamide and alternatives forms thereof (e.g., salts, hydrates, solvates, prodrugs, polymorphs and metabolites); pharmaceutical compositions which contain them and methods for treating cancer using them.

Abstract translation: 化合物4- {4 - [（{3-叔丁基-1- [3-（羟甲基）苯基] -1H-吡唑-5-基} - 氨基甲酰基）氨基] -3-氯苯氧基} -N-甲基吡啶 - （例如盐，水合物，溶剂合物，前药，多晶型物和代谢物）; 含有它们的药物组合物和使用它们治疗癌症的方法。

公开(公告)号：US20100040439A1

公开(公告)日：2010-02-18

申请号：US12440444

申请日：2007-09-08

Applicant: John Temple ,  Ian Kerrod ,  Alan Prile ,  Roger Smith ,  Stephen Hankey

Inventor： John Temple ,  Ian Kerrod ,  Alan Prile ,  Roger Smith ,  Stephen Hankey

IPC: B65H1/00

CPC classification number: G01N1/312 ,  G01N35/00029 ,  G01N35/00871 ,  G01N2001/315 ,  G01N2035/00079 ,  G01N2035/00089 ,  G01N2035/00138 ,  G01N2035/0462 ,  G01N2035/0493

Abstract: The present invention is concerned with a basket processing apparatus that includes a basket storage portion in a form of a horizontal load rail (2). A plurality of slide storage baskets (4) can be located in series on the rail (2). Each basket is “side loading” and the side loading aperture of each basket can be selectively covered by a slide retaining bar (6). When the baskets (4) are placed on the load rail (2) (e.g. by hooking or clipping the baskets onto the rail), the basket can be moved along the horizontal rail by a basket moving means. The arrangement of the rail and the basket moving means is such that the baskets can be pushed together and move as a “train”. Baskets moved to the pick-up end (12) of the rail can then be removed from the rail and processed. A vertical lift mechanism can be used to remove the basket and transport it to a processing device, for example a coverslipper.

Abstract translation: 本发明涉及一种篮子处理装置，其包括水平承载轨道（2）形式的篮子储存部分。 可以在轨道（2）上串联设置多个滑动存放篮（4）。 每个篮子是“侧面装载”，并且每个篮子的侧面装载孔可以被滑动保持杆（6）选择性地覆盖。 当篮子（4）放置在承载轨道（2）上（例如通过将篮子钩住或夹住轨道）时，篮子可以通过篮子移动装置沿着水平轨道移动。 轨道和篮子移动装置的布置使得篮子可以一起推动并作为“列车”移动。 移动到轨道的拾取端（12）的篮子然后可以从轨道移除并被处理。 可以使用垂直提升机构来移除篮子并将其运送到处理装置，例如盖玻片。

公开(公告)号：US20090253762A1

公开(公告)日：2009-10-08

申请号：US12206721

申请日：2008-09-08

Applicant: Roger Smith ,  Ann-Marie Campbell ,  Philip Coish ,  Miao Dai ,  Susan Jenkins ,  Derek Lowe ,  Stephen O'Connor ,  Ning Su ,  Gan Wang ,  Mingbao Zhang ,  Lei Zhu

Inventor： Roger Smith ,  Ann-Marie Campbell ,  Philip Coish ,  Miao Dai ,  Susan Jenkins ,  Derek Lowe ,  Stephen O'Connor ,  Ning Su ,  Gan Wang ,  Mingbao Zhang ,  Lei Zhu

IPC: A61K31/428 ,  C07D277/82 ,  C07D413/02 ,  A61K31/416 ,  A61K31/423 ,  C07D405/02

CPC classification number: C07D263/58 ,  C07D235/30 ,  C07D263/60 ,  C07D277/42 ,  C07D277/58 ,  C07D277/82 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12

Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.

公开(公告)号：US20080214545A1

公开(公告)日：2008-09-04

申请号：US11579093

申请日：2005-05-02

Applicant: Wendy Lee ,  Gaetan Ladouceur ,  Jacques Dumas ,  Roger Smith ,  Shihong Ying ,  Gan Wang ,  Zhi Chen ,  Qingjie Liu ,  Holia Hatoum Mokdad

Inventor： Wendy Lee ,  Gaetan Ladouceur ,  Jacques Dumas ,  Roger Smith ,  Shihong Ying ,  Gan Wang ,  Zhi Chen ,  Qingjie Liu ,  Holia Hatoum Mokdad

IPC: A61K31/5377 ,  C07D401/12 ,  C07D413/14 ,  A61P35/02 ,  A61P35/00 ,  A61K31/4439

CPC classification number: C07D401/12 ,  C07D405/14

Abstract: The present invention relates to compounds of formula (I), pharmaceutical compositions which contain them and methods for treating cancer using compounds of formula (I).

Abstract translation: 本发明涉及式（I）化合物，含有它们的药物组合物和使用式（I）化合物治疗癌症的方法。

公开(公告)号：US20070283287A1

公开(公告)日：2007-12-06

申请号：US11807704

申请日：2007-05-29

Applicant: Jacob Taylor ,  John Roberts ,  Clinton Oram ,  Ajay Gupta ,  Majed Itani ,  Sadek Baroudi ,  Roger Smith

Inventor： Jacob Taylor ,  John Roberts ,  Clinton Oram ,  Ajay Gupta ,  Majed Itani ,  Sadek Baroudi ,  Roger Smith

IPC: G06Q10/00

CPC classification number: G06Q30/06

Abstract: A software-based customer relationship management system and method.

公开(公告)号：US20070193195A1

公开(公告)日：2007-08-23

申请号：US11627738

申请日：2007-01-26

Applicant: Roger Smith

Inventor： Roger Smith

IPC: E04B1/38

CPC classification number: E04B5/12 ,  E04B1/2612

Abstract: A joist hanger is described which comprises one or more open-topped joist receiving sockets, each socket being defined by two side cheeks and a bridge section which joins the lower ends of the two side cheeks, the joist hanger further comprising one or more flanges by which the hanger can be secured to an abutting face and/or upper edge of a wall or beam, characterised in that the two side cheeks diverge from the bridge section to the open top of the joist receiving socket, so that the width of the socket is greater at the top than the bottom, such that a joist will fit snugly in the socket between the two side cheeks in the region of the bridge section but the upper portion of the socket is wider to facilitate entry thereinto of the joist.

Abstract translation: 描述了一种托梁悬挂器，其包括一个或多个开顶托梁接收插座，每个插座由两个侧面面板限定，桥接部分连接在两个侧面的下端，托梁架还包括一个或多个凸缘 其中衣架可以固定到壁或梁的邻接面和/或上边缘，其特征在于，所述两侧面颊从所述桥接部分向所述托梁接收座的敞开的顶部分开，使得所述插座的宽度 在顶部比底部更大，使得托梁将紧密地贴合在桥部分区域中的两个侧面之间的插座中，但是插座的上部较宽以便于托梁的进入。

公开(公告)号：US20060259036A1

公开(公告)日：2006-11-16

申请号：US11489319

申请日：2006-07-19

Applicant: Philip Tetzlaff ,  James Cunningham ,  Michael Moses ,  Roger Smith ,  Kristin Johnson ,  Paul Romero

Inventor： Philip Tetzlaff ,  James Cunningham ,  Michael Moses ,  Roger Smith ,  Kristin Johnson ,  Paul Romero

IPC: A61B18/14

CPC classification number: A61B18/1442 ,  A61B17/29 ,  A61B18/1445 ,  A61B2017/2945 ,  A61B2018/1432 ,  A61B2018/145 ,  A61B2018/146 ,  A61B2018/1495 ,  A61B2090/034

Abstract: A removable electrode assembly for use in combination with a forceps having opposing end effectors and a handle for effecting movement of the end effectors relative to one another. The electrode assembly includes a housing which is removably engageable with the forceps and a pair of electrodes which are attachable to a distal end of the housing. The electrodes are removably engageable with the end effectors of the forceps such that the electrodes reside in opposing relation relative to one another. The electrode assembly also includes a cover plate which is removably attachable to the housing and at least one stop member for controlling the distance between the opposing electrodes. The stop member is selectively engageable with the electrodes.

公开(公告)号：US07091228B2

公开(公告)日：2006-08-15

申请号：US10839833

申请日：2004-05-06

Applicant: Roger Smith ,  Ann-Marie Campbell ,  Philip Coish ,  Miao Dai ,  Susan Jenkins ,  Derek Lowe ,  Stephen O'Connor ,  Ning Su ,  Gan Wang ,  Mingbao Zhang ,  Lei Zhu

Inventor： Roger Smith ,  Ann-Marie Campbell ,  Philip Coish ,  Miao Dai ,  Susan Jenkins ,  Derek Lowe ,  Stephen O'Connor ,  Ning Su ,  Gan Wang ,  Mingbao Zhang ,  Lei Zhu

IPC: A61K31/428 ,  A61K31/426 ,  C07D277/82 ,  C07D277/42

CPC classification number: C07D263/58 ,  C07D235/30 ,  C07D263/60 ,  C07D277/42 ,  C07D277/58 ,  C07D277/82 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12

Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.