公开(公告)号：US20020133053A1

公开(公告)日：2002-09-19

申请号：US09805581

申请日：2001-03-13

Applicant: Clemson University

Inventor： Robert A. Latour JR.

IPC: A61F002/00

CPC classification number: A61F2/0022

Abstract: An intraurethral device that can be used to inhibit leakage of urine due to incontinence is provided. The intraurethral device can include a urethral plug made from a biocompatible, flexible material. The intraurethral device can also include a first insertion element in operative communication with a second insertion element to facilitate self-insertion of the urethral plug into the urethra. Furthermore, in some instances, various mechanisms can be provided to keep the intraurethral device substantially sterile and/or clean prior to and/or during the insertion process.

Abstract translation: 提供了可用于抑制由于尿失禁引起的尿泄漏的尿道内装置。 尿道内装置可包括由生物相容的柔性材料制成的尿道塞。 尿道内装置还可以包括与第二插入元件可操作地连通的第一插入元件，以便于将尿道塞自行插入尿道。 此外，在一些情况下，可以提供各种机构以在插入过程之前和/或期间保持尿道内装置基本上无菌和/或清洁。

公开(公告)号：US20020118435A1

公开(公告)日：2002-08-29

申请号：US09998922

申请日：2001-11-30

Applicant: Clemson University

Inventor： Stephen H. Foulger ,  Ping Jiang ,  Amanda C. Lattam ,  Travis Baughman ,  John Ballato ,  Dennis W. Smith

IPC: G02F001/15

CPC classification number: G01N33/54313 ,  B01J2219/005 ,  B01J2219/00576 ,  B01J2219/00702 ,  G01N33/54373 ,  G01N33/545 ,  Y10T436/177692

Abstract: Crystalline colloidal arrays (CCA) which have been encapsulated in a polymer matrix to produce more robust polymerized crystalline colloidal arrays (PCCA) are provided. The PCCA's of the present invention can be in the form of a hydrogel which can be compatible for use with a biological system. The polymer matrix of the PCCA is formed of polymerized poly(ethylene glycol) based monomer units which can provide a desired functionality to the PCCA. The PCCA can be formed to exhibit a photonic bandgap at a certain wavelength. The photonic bandgap can be capable of shifting upon some form of environmental stimulation rendering the PCCA suitable for many optical applications, including active photonic switching and sensory applications.

Abstract translation: 提供已经封装在聚合物基质中以产生更坚固的聚合晶体胶体阵列（PCCA）的结晶胶体阵列（CCA）。 本发明的PCCA可以是能够与生物系统一起使用的水凝胶的形式。 PCCA的聚合物基质由聚合的基于聚（乙二醇）的单体单元形成，其可以为PCCA提供期望的功能。 可以形成PCCA以在一定波长处展现光子带隙。 光子带隙能够在某种形式的环境刺激下转变，使PCCA适用于许多光学应用，包括有源光子切换和感官应用。

公开(公告)号：US12276896B2

公开(公告)日：2025-04-15

申请号：US17838632

申请日：2022-06-13

Applicant: Clemson University

Inventor： Eric G. Johnson ,  Jerome Keith Miller ,  Richard Watkins ,  Kaitlyn Morgan ,  Wenzhe Li ,  Yuan Li

IPC: G02F1/33 ,  H04B10/27

Abstract: This system and method of for providing a tunable orbital angular momentum system for providing higher order Bessel beams comprising: an acousto-optical deflector configured to receive an input beam, deflect a first portion of the input beam a first deflection angle relative to an axis of propagation and along an optical axis and deflect a second portion of the input beam a second deflection angle relative to the optical axis; a line generator disposed along the optical angle for receiving the first portion and the second portion of the input beam and provide an elliptical Gaussian mean; a log-polar optics assembly disposed along the optical angle for receiving the elliptical Gaussian beam and wrapping the elliptical Gaussian beam with an asymmetric ring; and, a Fourier lens configured to receive the wrapped elliptical Gaussian beam.

公开(公告)号：US20240409842A1

公开(公告)日：2024-12-12

申请号：US18734086

申请日：2024-06-05

Applicant: CLEMSON UNIVERSITY

Inventor： Daniel C. Whitehead ,  Carlos D. Garcia ,  Ezequiel Martin Vidal

IPC: C11B3/10 ,  B01J20/24

Abstract: Methods and compositions are described that are useful for the refinement of animal or plant based fats or oils, such as rendered animal fats or used cooking oils. The methods can be utilized to remove metal and inorganic contaminants from the fats or oils. Refined products of the methods can be used to produce biodiesel that is compliant with ASTM B6751 for B100, and D7467 for B6 to B20.

公开(公告)号：US20240247077A1

公开(公告)日：2024-07-25

申请号：US18420450

申请日：2024-01-23

Applicant: Clemson University Research Foundation

Inventor： Charles David Rice

IPC: C07K16/40 ,  G01N33/573 ,  A61K39/00

CPC classification number: C07K16/40 ,  G01N33/573 ,  A61K2039/505 ,  C07K2317/14 ,  C07K2317/33 ,  C07K2317/565

Abstract: This invention is directed to a monoclonal antibody or an antigen binding fragment thereof targeting the expression and function of CYP1A1 with cross reactivity across the vertebrate taxa. This invention is also directed to nucleic acid molecules, vectors, host cells and compositions comprising the same, as well as methods for use of the same and for producing the same.

公开(公告)号：US12038382B2

公开(公告)日：2024-07-16

申请号：US17378093

申请日：2021-07-16

Applicant: CLEMSON UNIVERSITY

Inventor： Hai Yao ,  Tong Ye ,  Peng Chen ,  Xun Chen

IPC: G01N21/64 ,  G02B21/00 ,  G06T7/00

CPC classification number: G01N21/6486 ,  G01N21/6458 ,  G02B21/0032 ,  G02B21/0076 ,  G02B21/008 ,  G06T7/0016 ,  G01N2201/0635

Abstract: Herein are described data acquisition systems and methods applying such systems to determine three-dimensional (3D) diffusion tensors, and simultaneously, to perform 3D structure imaging. Example data acquisition systems can include computing systems in communication with modified light sheet microscopes that are configured for high-speed volumetric imaging to record 3D diffusion processes and high-resolution 3D structural imaging.

公开(公告)号：US11835526B2

公开(公告)日：2023-12-05

申请号：US17672586

申请日：2022-02-15

Applicant: University of Washington ,  Clemson University Research Foundation

Inventor： Daniel T. Chiu ,  Changfeng Wu ,  Jason McNeill ,  Jiangbo Yu

IPC: G01N33/58 ,  C09K11/06

CPC classification number: G01N33/587 ,  C09K11/06 ,  G01N33/582

Abstract: The present invention provides, among other aspects, functionalized chromophoric polymer dots comprising a hydrophobic core and a hydrophilic cap, and bioconjugates thereof. Also provided are improved methods for preparing functionalized chromophoric polymer dots. Methods for in vivo imaging and molecular labeling are also disclosed.

公开(公告)号：US20230382769A1

公开(公告)日：2023-11-30

申请号：US17826956

申请日：2022-05-27

Applicant: BATTELLE SAVANNAH RIVER ALLIANCE, LLC ,  CLEMSON UNIVERSITY

Inventor： JAKE W. AMOROSO ,  KYLE S. BRINKMAN ,  JIANHUA TONG ,  JUN GAO ,  YUQING MENG ,  JAMES M. BECNEL

IPC: C02F1/28 ,  B01D71/02 ,  B01D15/20 ,  B01D15/18 ,  C02F1/44 ,  G21F9/12

CPC classification number: C02F1/281 ,  B01D71/0271 ,  B01D15/203 ,  B01D15/1885 ,  B01D15/1807 ,  C02F1/44 ,  G21F9/12 ,  C02F2303/16

Abstract: Methods and systems directed to the separation of a heavy hydrogen isotope, e.g., tritium, from an aqueous stream are described. The methods and systems incorporate a separation media that includes a proton conducting ceramic that at low temperatures preferentially adsorbs heavy hydrogen isotopes and at high temperature preferentially adsorbs lighter heavy hydrogen isotopes. The methods can be temperature controlled to sequentially purify a contaminated stream and regenerate the separation media. The separation media can be free of traditional hydrogen isotope exchange catalyst materials.

公开(公告)号：US11773362B2

公开(公告)日：2023-10-03

申请号：US17244447

申请日：2021-04-29

Applicant: CLEMSON UNIVERSITY RESEARCH FOUNDATION

Inventor： Leslie Sierad ,  Christopher Delaney ,  Richard Pascal, III ,  Dan Simionescu ,  Agneta Simionescu

IPC: C12M3/00 ,  C12M1/00 ,  C12M1/34 ,  C12M1/42

CPC classification number: C12M41/40 ,  C12M21/08 ,  C12M23/00 ,  C12M23/44 ,  C12M29/00 ,  C12M29/12 ,  C12M35/04

Abstract: Bioreactors and components of bioreactors are described as may be beneficially utilized in development and conditioning of cellular materials for study or implant. The bioreactors are modular, and components of the bioreactors can be easily assembled with alternatives provided to develop specific, predetermined conditioning environments for cellular materials (e.g., implantable tissue). By selection of one of multiple alternative compliance chambers, a bioreactor can be utilized to condition tissue in a low-pressure circuit (e.g., a pulmonary heart circuit), and by utilization of an alternative compliance chamber, the bioreactor can instead condition tissue in a high-pressure circuit (e.g., an aortic heart circuit).

公开(公告)号：US11762370B2

公开(公告)日：2023-09-19

申请号：US16902056

申请日：2020-06-15

Applicant: Clemson University

Inventor： Victor B. Zordan ,  Ella A Moore ,  Michael Porter ,  Ioannis Karamouzas

IPC: G05B19/4155

CPC classification number: G05B19/4155 ,  G05B2219/34177

Abstract: This system is directed to a computerized system for development of textiles with modified physical properties through stitching and can include a set of non-transitory computer readable instructions configured for: receiving a design pattern representing desired physical properties of a textile having a higher stiffness area and a lower stiffness area; developing a contiguous stitching pattern constrained by a pattern perimeter boundary and having a continuous stitching path, developing a first stiffness area within the contiguous stitching pattern having a first area of density, developing a second stiffness area within the contiguous stitching pattern having a second area of density wherein the first area of density has more stitch density than the second area of density, and transmitting the contiguous stitching pattern to an embroidery machine configured to provide a textile having the contiguous stitching pattern incorporating into the textile.