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    THROMBOLYSIS IN RETINAL VESSELS WITH ULTRASOUND
    63.
    发明申请
    THROMBOLYSIS IN RETINAL VESSELS WITH ULTRASOUND 审中-公开
    超声波血管内血栓形成

    公开(公告)号：US20140243712A1

    公开(公告)日：2014-08-28

    申请号：US13780535

    申请日：2013-02-28

    Applicant: Mark Humayun ,  Xiaochen Xu ,  Qifa Zhou ,  K. Kirk Shung ,  Hossein Ameri ,  Gerald Chader

    Inventor： Mark Humayun ,  Xiaochen Xu ,  Qifa Zhou ,  K. Kirk Shung ,  Hossein Ameri ,  Gerald Chader

    IPC: A61N7/00

    CPC classification number: A61N7/00 ,  A61B17/22012 ,  A61F9/00745 ,  A61N2007/0047

    Abstract: Systems and methods are described providing for the use of ultrasound energy to effect the dislodging of one or more blood clots inside blood vessels. Such clots can include those inside retinal vessels, especially in patients with central retinal vein occlusion. Embodiments of the present disclosure may be used for any retinal arterial or venous occlusion. In exemplary embodiments, a small probe can be inserted into the eye of a patient and placed over the retinal vessels. Acoustic streaming created by the probe can be directed to an area or region including targeted blood vessels, resulting in increased flow in one or more retinal veins and facilitating or effecting mechanical dislodging of one or more blood clots in the targets blood vessels. Exemplary embodiments can utilize ultrasonic energy produced at a frequency of approximately 44 MHz to 46 MHz with pulse repetition frequencies of approximately 100 Hz to 100 kHz.

    Abstract translation: 描述了使用超声能量来实现血管内的一个或多个血块的移动的系统和方法。 视网膜血管，包括视网膜中央静脉阻塞的患者尤其如此。 本公开的实施方案可用于任何视网膜动脉或静脉闭塞。 在示例性实施例中，可以将小探针插入患者的眼睛并放置在视网膜血管上。 由探针产生的声流可以被引导到包括目标血管的区域或区域，导致一个或多个视网膜静脉中的流量增加并且促进或实现靶血管中的一个或多个血块的机械移除。 示例性实施例可以利用大约44MHz至46MHz的频率产生的超声能量，脉冲重复频率约为100Hz至100kHz。

    Implantable Intraocular Pressure Drain
    68.
    发明申请
    Implantable Intraocular Pressure Drain 失效
    植入式眼内压排水

    公开(公告)号：US20120289883A1

    公开(公告)日：2012-11-15

    申请号：US13555329

    申请日：2012-07-23

    Applicant: Ellis Fan-chuin Meng ,  Po-Jui Chen ,  Damien Rodger ,  Yu-Chong Tai ,  Mark Humayun

    Inventor： Ellis Fan-chuin Meng ,  Po-Jui Chen ,  Damien Rodger ,  Yu-Chong Tai ,  Mark Humayun

    IPC: A61F9/00 ,  A61M1/00

    CPC classification number: A61F9/00781 ,  A61B3/16 ,  A61B5/4836 ,  A61B5/6821 ,  A61B2562/0247 ,  A61B2562/028 ,  A61B2562/12 ,  F16K99/0009 ,  F16K99/0057 ,  F16K2099/0086

    Abstract: An implanted parylene tube shunt relieves intra-ocular pressure. The device is implanted with an open end in the anterior chamber of the eye, allowing excess fluid to be drained through the tube out of the eye. In one embodiment, only a first end of the tube implanted into the anterior chamber of the eye is open. Intra-ocular pressure (IOP) is then monitored, for example utilizing an implanted sensor. When IOP exceeds a critical valve, a practitioner intervenes, puncturing with a laser a thinned region of the tube lying outside the eye, thereby initiating drainage of fluid and relieving pressure. In accordance with alternative embodiments, the both ends of the tube are open, and the tube includes a one-way valve configured to permit drainage where IOP exceeds the critical value. The tube may include projecting barbs to anchor the tube in the eye without the need for sutures.

    Abstract translation: 植入的聚对二甲苯管分流器可减轻眼内压力。 该装置在眼睛的前房中植入开放端，允许多余的液体通过管排出眼睛。 在一个实施例中，仅植入眼睛前房的管的第一端是开放的。 然后监测眼内压（IOP），例如利用植入的传感器。 当IOP超过临界阀时，从业者介入，用激光穿刺位于眼睛外部的管的薄的区域，从而引起流体排出并释放压力。 根据替代实施例，管的两端是开放的，并且管包括被配置为允许IOP超过临界值的排水的单向阀。 管可以包括突出的倒钩以将管锚定在眼睛中而不需要缝线。

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