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公开(公告)号:US20210307611A1
公开(公告)日:2021-10-07
申请号:US16838875
申请日:2020-04-02
Applicant: University of Rochester
Inventor: Jose Fernando ZVIETCOVICH ZEGARRA , Jannick P. Rolland , Cristina Canavesi , Kevin J. Parker
Abstract: a) A Gabor domain optical coherence microscopy (GD-OCM) system providing high resolution of structural and motion imaging of objects such as tissues is combined with the use of reverberant shear wave fields (RevSW) or longitudinal shear waves (LSW) and two novel mechanical excitation sources: a coaxial coverslip excitation (CCE) and a multiple pronged excitation (MPE) sources providing structured and controlled mechanical excitation in tissues and leading to accurate derivation of elastographic properties. Alternatively, general optical computed tomography (OCT) is combined with RevSW or LWC in the object to derive elastographic properties. The embodiments include (a) GD-OCM with RevSW; (b) GD-OCM with LSW; (c) General OCT with RevSW; and General OCT with LSW.
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公开(公告)号:US20210284643A1
公开(公告)日:2021-09-16
申请号:US16321589
申请日:2017-07-28
Applicant: University of Massachusetts , University of Rochester
IPC: C07D487/04 , A61K45/06 , A61P31/18 , A61P35/00
Abstract: The present disclosure provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. Related pharmaceutical compositions are disclosed. Methods of treatment with the disclosed compounds and compositions are also disclosed. Related kits are further disclosed.
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63.
公开(公告)号:US11110147B2
公开(公告)日:2021-09-07
申请号:US16489890
申请日:2018-03-01
Applicant: ROUSSELOT B.V. , UNIVERSITY OF ROCHESTER
Inventor: Michael Zuscik , Janne Prawitt , Eric Schott , Robert Mooney , Christopher Farnsworth
IPC: A61K38/01 , A23K20/147 , A23L33/18 , A61P19/02 , A61P1/00
Abstract: The invention generally relates to pharmaceuticals and/or nutraceuticals. More particularly, the invention provides compositions of collagen-based peptides and specific digestive tract microbes useful for supporting or promoting joint, skin and/or bone health, and methods of preparation and use thereof. The invention further provides for the use of compositions of collagen-based peptides as a prebiotic for modulating the gut microbiome.
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公开(公告)号:US11098999B2
公开(公告)日:2021-08-24
申请号:US16220321
申请日:2018-12-14
Applicant: University of Rochester
Inventor: Di Xu , Jannick Rolland-Thompson
Abstract: A cascaded interferometric system for Fourier domain optical coherence tomography (OCT) in which the output of one sub-system interferometer is directed through a second sub-system interferometer for performing the Fourier transform in hardware.
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公开(公告)号:US20210247239A1
公开(公告)日:2021-08-12
申请号:US16787681
申请日:2020-02-11
Applicant: University of Rochester
Inventor: Abdelrahman G. Qoutb , Eby G. Friedman
Abstract: A hybrid integrated thermal sensor device includes a magnetic tunnel junction (MTJ) device electrically coupled in series with at least one CMOS transistor and disposed between a voltage rail terminal and a ground terminal. An output terminal is electrically coupled to a drain of the at least one CMOS transistor. The MTJ operates in an anti-parallel state and the output terminal provides a voltage indicative of a temperature of the MTJ device based on an MTJ antiparallel resistance. A distributed sensor network for real-time thermal mapping of an integrated circuit (IC) is also described.
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公开(公告)号:US11076231B2
公开(公告)日:2021-07-27
申请号:US16896572
申请日:2020-06-09
Applicant: THE UNIVERSITY OF ROCHESTER
Inventor: David Allan Anderson , Mark F. Bocko , Michael Charles Heilemann
Abstract: Systems and methods of driving plate loudspeakers with different parameters based on frequency region in a way similar to typical cone driver crossover networks are described. These systems and methods may be implemented using arrays of independently controlled drivers which allow a designer to emphasize or de-emphasize certain modes in certain frequency bands. Tuning the characteristics of the plate's motion can also affect the acoustical properties in a larger space rather than just at a single location. The systems and methods described herein can grant a designer a degree of control over the characteristics and performance of the plate.
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公开(公告)号:US11065274B2
公开(公告)日:2021-07-20
申请号:US15747207
申请日:2016-07-26
Applicant: University of Rochester
Inventor: Paul M. Dunman
IPC: A61K33/30 , A61K31/555 , A61K31/625 , A61K31/635 , A61P31/04 , A61K9/00 , A61K33/38
Abstract: The present invention features a composition comprising zinc pyrithione and silver sulfiadizine, a formulation thereof and a method of treating microbial infection using the composition.
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公开(公告)号:US20210196520A1
公开(公告)日:2021-07-01
申请号:US17055317
申请日:2019-05-14
Applicant: University of Rochester , Clerio Vision, Inc. , Arizona Board of Regents on Behalf of the University of Arizona
Inventor: Leonard Zheleznyak , Corey Leeson , Jonathan D. Ellis , Theodore Foos , Sam C. Butler
IPC: A61F9/008
Abstract: Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or ocular tissues is performed to address various types of vision correction, and the laser induced changes to the refractive index avoid ablation and removal of the optical polymer materials while minimizing scattering losses.
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公开(公告)号:US20210177577A1
公开(公告)日:2021-06-17
申请号:US17188134
申请日:2021-03-01
Applicant: University of Rochester
Inventor: Leonard Zheleznyak , Scott Catlin
Abstract: Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or optical tissues is performed to address various types of vision correction.
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公开(公告)号:US20210177576A1
公开(公告)日:2021-06-17
申请号:US17188124
申请日:2021-03-01
Applicant: University of Rochester
Inventor: Leonard Zheleznyak , Scott Catlin
Abstract: Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or optical tissues is performed to address various types of vision correction.
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