公开(公告)号：US11707213B2

公开(公告)日：2023-07-25

申请号：US16944734

申请日：2020-07-31

Applicant: BIONIME CORPORATION

Inventor： Chun-Mu Huang ,  Chieh-Hsing Chen

IPC: A61B5/145 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/0004 ,  A61B5/14503 ,  A61B5/688 ,  A61B2562/166 ,  A61B2562/226 ,  A61B2562/227

Abstract: A physiological signal monitoring device includes a sensing member and a transmitter connected to the sensing member and including a circuit board that has electrical contacts, and a connecting port, which includes a socket communicated to the circuit board and a plurality of conducting springs disposed at two opposite sides of the socket. The sensing member is removably inserted into the socket. The conducting springs are electrically connected to the electrical contacts and the sensing member for enabling electric connection therebetween. Each of the conducting springs is frictionally rotated by the sensing member during insertion of the sensing member into the socket and removal of the sensing member from the socket.

公开(公告)号：US11678846B2

公开(公告)日：2023-06-20

申请号：US16945694

申请日：2020-07-31

Applicant: BIONIME CORPORATION

Inventor： Chun-Mu Huang ,  Chieh-Hsing Chen ,  Chen-Hao Lee ,  Kuan-Lin Chang

IPC: A61B17/34 ,  A61B5/00

CPC classification number: A61B5/6848 ,  A61B17/3468 ,  A61B17/3496 ,  A61B2562/164

Abstract: An insertion device includes a cover body, an insertion module. The insertion module is disposed in the cover body, and includes a main body, an insertion seat, a first elastic member, a retraction seat and a second elastic member. When the cover body is depressed, the insertion seat is driven by the first elastic member to perform an automatic-insertion operation and to collapse a limiting structure between the insertion seat and the cover body. A limiting structure between the insertion seat and the retraction seat collapses upon the collapse of the limiting structure between the insertion seat and the cover body, so that the retraction seat is driven by the second elastic member to perform an automatic-retraction operation.

公开(公告)号：US11521731B2

公开(公告)日：2022-12-06

申请号：US17144266

申请日：2021-01-08

Applicant: BIONIME CORPORATION

Inventor： Chieh-Hsing Chen ,  Chun-Mu Huang

IPC: G16H20/17 ,  A61M5/172 ,  A61B5/00 ,  A61B5/07 ,  H02J7/00 ,  G16H40/67 ,  A61B5/145 ,  H01R13/631 ,  H01R13/642 ,  H01R13/66 ,  H01R33/945 ,  H01R43/26 ,  H01R13/639

Abstract: A charging device for a physiological signal transmitter is disclosed, wherein the physiological signal transmitter is to receive and externally transmit a physiological signal from a subcutaneous tissue of a living body, and has a first electrical connecting port. The charging device comprises a transmitter placing seat, a charging module and a locking module. The transmitter placing seat includes a bearing surface, and a first opening. The bearing surface disposes thereon the physiological signal transmitter; and the first opening aligns therewith the first electrical connecting port of the physiological signal transmitter. The charging module includes a second electrical connecting port, a third electrical connecting port and a circuit assembly. The second electrical connecting port is disposed in the first opening and moveable between a first position and a second position. The third electrical connecting port is for connecting thereto a power source. The circuit assembly is for performing charging and charging control on the physiological signal transmitter, and the circuit assembly is electrically connected to the second electrical connecting port and the third electrical connecting port. The locking module is extendable or retractable on the bearing surface for releasably positioning the physiological signal transmitter, wherein the charging module is driven to move the second electrical connecting port from the first position to the second position to be electrically connected to the first electrical connecting port, and the locking module is driven to protrude out of the bearing surface to fix the transmitter.

公开(公告)号：US11426517B2

公开(公告)日：2022-08-30

申请号：US16519622

申请日：2019-07-23

Applicant: BIONIME CORPORATION

Inventor： Chun-Mu Huang ,  Chieh-Hsing Chen ,  Jia-Nan Shen ,  Kuan-Lin Chang

IPC: A61M5/172 ,  A61B5/00 ,  A61M5/142 ,  A61M5/158

Abstract: An elastic physiological patch includes a patch assembly and an implant assembly. The patch assembly includes an electronic device, and a soft patch body defining a chamber for receiving the electronic device. The implant assembly is mountable to the electronic device and includes an implant which is capable of being driven to partially pass through the patch body and which is adapted to be implanted in the skin of a subject. The implant and the patch body cooperatively seal the chamber.

公开(公告)号：US11315672B2

公开(公告)日：2022-04-26

申请号：US17144203

申请日：2021-01-08

Applicant: BIONIME CORPORATION

Inventor： Chieh-Hsing Chen ,  Chun-Mu Huang

IPC: G08B25/10 ,  G16H20/17 ,  A61M5/172 ,  A61B5/00 ,  A61B5/07 ,  H02J7/00 ,  G16H40/67 ,  A61B5/145 ,  H01R13/631 ,  H01R13/642 ,  H01R13/66 ,  H01R33/945 ,  H01R43/26 ,  H01R13/639

Abstract: A charging device for a physiological signal transmitter is disclosed, wherein the physiological signal transmitter is to receive and transmit a physiological signal from a subcutaneous tissue of a living body, and has a first electrical connecting port. The charging device comprises a body including a placing portion, a charging module and an operating module. The placing portion disposes thereon the physiological signal transmitter, and includes a bearing surface and a first opening. The bearing surface disposes thereon the physiological signal transmitter, and the first opening aligns therewith the first electrical connecting port of the physiological signal transmitter. The charging module is accommodated in the body and includes a second electrical connecting port, a third electrical connecting port and a circuit assembly. The second electrical connecting port is disposed in the opening and protrusive beyond or beneath the bearing surface. The third electrical connecting port is connected to a power source. The circuit assembly is configured to control a charging on the physiological signal transmitter, and electrically connected to the second electrical connecting port and the third electrical connecting port. The operating module is accommodated in the body, and coupled with the charging module, wherein when the physiological signal transmitter is placed on the bearing surface and in a first operating state, the operating module protrudes the second electrical connecting port beyond the bearing surface to electrically connect with the first electrical connecting port.

公开(公告)号：US20210218252A1

公开(公告)日：2021-07-15

申请号：US17138120

申请日：2020-12-30

Applicant: BIONIME CORPORATION

Inventor： Chieh-Hsing Chen ,  Chun-Mu Huang ,  Tung-Liang Liu

IPC: H02J7/00 ,  A61B5/07 ,  A61B5/00

Abstract: A charging device for a physiological signal transmitter used to receive a physiological signal from the subcutaneous tissue of a living body and having a first electrical connecting port is disclosed. The charging device includes a transmitter placing seat and a charging module. The transmitter placing seat includes a bearing surface for placing the physiological signal transmitter and an opening configured to align with the first electrical connection port of the physiological signal transmitter. The charging module includes a second electrical connecting port, a third electrical connecting port, a circuit assembly and a control module. The second electrical connecting port is disposed in the opening, and driven to move between a first position and a second position. The third electrical connecting port connects to a power source.

公开(公告)号：US20210030362A1

公开(公告)日：2021-02-04

申请号：US16945652

申请日：2020-07-31

Applicant: BIONIME CORPORATION

Inventor： Chun-Mu Huang ,  Chieh-Hsing Chen ,  Chen-Hao Lee ,  Kuan-Lin Chang

IPC: A61B5/00 ,  A61B90/00

Abstract: An insertion device includes an upper casing, a lower casing and an insertion module. When the lower casing is coupled to the upper casing, an abutment portion of the lower casing limits movement of a casing engaging structure of the upper casing, such that the upper casing cannot move downwardly so as to prevent unintentional insertion operation of the insertion device.

公开(公告)号：US20210030329A1

公开(公告)日：2021-02-04

申请号：US16945292

申请日：2020-07-31

Applicant: BIONIME CORPORATION

Inventor： Chun-Mu Huang ,  Chieh-Hsing Chen

IPC: A61B5/145 ,  A61B5/1473

Abstract: The present invention provides a measuring method for prolonging a usage lifetime of a micro biosensor implanted subcutaneously to measure a physiological signal associated with an analyte. The micro biosensor includes a working electrode and a counter electrode, wherein the counter electrode includes silver and a silver halide having an initial amount. The method includes cyclic steps of: applying a measurement voltage to drive the working electrode to measure the physiological signal, where the silver halide is consumed by a specific amount; stopping applying the measurement voltage; and whenever the physiological parameter is obtained, applying a replenishment voltage to drive the counter electrode, thereby the silver halide of a replenishment amount being replenished to the counter electrode, wherein a guarding value of a sum of the replenishment amount and the initial amount subtracting the consumption amount is controlled within a range of the initial amount plus or minus a specific value.

公开(公告)号：US20210030328A1

公开(公告)日：2021-02-04

申请号：US16944734

申请日：2020-07-31

Applicant: BIONIME CORPORATION

Inventor： Chun-Mu Huang ,  Chieh-Hsing Chen

IPC: A61B5/145 ,  A61B5/00

Abstract: A physiological signal monitoring device includes a sensing member and a transmitter connected to the sensing member and including a circuit board that has electrical contacts, and a connecting port, which includes a socket communicated to the circuit board and a plurality of conducting springs disposed at two opposite sides of the socket. The sensing member is removably inserted into the socket. The conducting springs are electrically connected to the electrical contacts and the sensing member for enabling electric connection therebetween. Each of the conducting springs is frictionally rotated by the sensing member during insertion of the sensing member into the socket and removal of the sensing member from the socket.

公开(公告)号：US20210030319A1

公开(公告)日：2021-02-04

申请号：US16945203

申请日：2020-07-31

Applicant: BIONIME CORPORATION

Inventor： Chun-Mu Huang ,  Chieh-Hsing Chen

IPC: A61B5/145 ,  A61B5/00 ,  A61B17/34

Abstract: An implantation device for prompt subcutaneous implantation of a sensor to measure a physiological signal of an analyte in a biofluid of a living body is disclosed. The implantation device includes a housing, an implantation module, a detachable module and a bottom cover. The housing has a bottom opening. The implantation module includes an implanting device and a needle extracting device. The detachable module includes the sensor detachably engaged with the implantation module; and a base configured to mount the sensor thereon. The bottom cover is detachably coupled to the bottom opening so that the housing and the bottom cover together form an accommodating space. The implantation module and the detachable module are accommodated in the accommodating space. The bottom cover has an operating portion configured to bear a force, and a supporting portion is formed on the opposite end of the operating portion.