公开(公告)号：US11904288B1

公开(公告)日：2024-02-20

申请号：US18108895

申请日：2023-02-13

Applicant: TRUCAPSOL LLC

Inventor： Jiten Odhavji Dihora ,  Praveen Bachawala ,  Monoj Pramanik

IPC: B01J13/16 ,  A61K9/50 ,  B01J13/14 ,  B01J13/22 ,  B01J13/04 ,  B01J13/08

CPC classification number: B01J13/14 ,  B01J13/043 ,  B01J13/08 ,  B01J13/22

Abstract: Disclosed is a composition including microcapsules, which include: a core composition including at least one hydrophobic active ingredient; and a wall partially or completely surrounding the core, wherein the wall includes at least one wall material that is a reaction product of a wall-forming reaction selected from: (A) a Type A reaction including: (i) reacting an amine moiety containing material with an epoxy and optionally an isocyanate; and (ii) reacting the isocyanate and at least one polyol; (B) a Type B reaction of a hydrolyzed protein with at least one of an epoxy and an organofunctional silane, and optionally an isocyanate; and (C) a Type C reaction of an amine moiety containing material with at least one of an epoxy and an oil soluble dialdehyde, and optionally an isocyanate. A method for preparing the composition is also disclosed.

公开(公告)号：US20240050914A1

公开(公告)日：2024-02-15

申请号：US18278033

申请日：2022-02-21

Applicant: Microcaps AG

Inventor： Kaj Pletscher

IPC: B01J13/04 ,  B01J13/20

CPC classification number: B01J13/043 ,  B01J13/206

Abstract: A method for generating capsules includes: a. providing in a first chamber a dispersed phase, the dispersed phase including a solution including a first solvent and a matrix-forming agent, the matrix-forming agent is a solid in its pure state and the first solvent and the matrix-forming agent are configured such that the matrix-forming agent is soluble in the first solvent; and b. providing in a second chamber a continuous phase, the continuous phase including a second solvent. The first and second chambers are fluidic connected by channel(s). The method further includes: c. guiding the dispersed phase from the first chamber through the channel(s) into the second chamber to form an emulsion or a dispersion including a plurality of droplets of the dispersed phase, in the continuous phase; and d. removing the first solvent from the droplets of the dispersed phase and solidifying the matrix-forming agent to form a capsule.

公开(公告)号：US11845052B2

公开(公告)日：2023-12-19

申请号：US17552011

申请日：2021-12-15

Applicant: FONA TECHNOLOGIES, LLC

Inventor： Robert M. Sobel ,  Benjamin Bunchean ,  Chin-Ping Su ,  Michael Gundlach ,  Thomas E. Ackerman, Jr. ,  Glenn R. St. Peter

IPC: B01J13/04 ,  F26B3/12 ,  F26B3/34 ,  A23L27/00 ,  C11D3/50 ,  A23P10/30

CPC classification number: B01J13/043 ,  A23L27/72 ,  A23P10/30 ,  C11D3/505 ,  F26B3/12 ,  F26B3/34 ,  A23V2002/00

Abstract: Disclosed is an electrostatic spray drying process for encapsulating a core material, such as a volatile flavor oil, within a carrier or wall material. The process is achieved by atomizing a liquid emulsion comprising the core material and the wall material, applying an electrostatic charge at the site of atomization, and drying the atomized emulsion into an encapsulated, free-flowing powder. Applying an electrostatic charge at the site of atomization allows the spray drying to be accomplished at significantly reduced temperatures, in particular, inlet temperatures in the range of 25° C. to 110° C., and outlet temperatures in the range of 25° C. to 80° C. The low drying temperatures impart improvements in the resulting encapsulated powdered product, including better retention of volatile flavor components, a flavor profile comparable to that of the starting liquid formulation, and better hydration and dissolution in water-based applications.

公开(公告)号：US20190193042A1

公开(公告)日：2019-06-27

申请号：US15767696

申请日：2015-10-12

Applicant: Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory

Inventor： Xinde Xu ,  Bin Shao ,  Di Zhou ,  Lihua Zhang

IPC: B01J13/04 ,  A61K9/50

CPC classification number: B01J13/043 ,  A23P10/30 ,  A61K9/5036 ,  A61K9/5052 ,  A61K9/5057 ,  A61K9/5089 ,  B01J13/04

Abstract: The present invention provides a method for drying high-stability microcapsule particles containing multiple double bonds fat soluble nutrients comprises: a) preparing a microcapsule emulsion containing multiple double bonds fat soluble nutrients, performing spray granulation on the microcapsule emulsion in a spray system (1), and meanwhile blasting air into the spray system (1), the blasted air wrapping adsorption materials, and the microcapsule emulsion being immediately solidified and sized after coming into contact with the air, so as to obtain liquid droplets having surfaces to which adsorption materials are adsorbed; b) performing fluidized drying on the liquid droplets having surfaces to which the adsorption materials are adsorbed in the step a) in a multi-stage fluidized bed system (5); c) collecting non-adsorbed adsorption materials by means of an adsorption material dust removal, recovery and circulation system; and d) collecting microcapsule particle products.

公开(公告)号：US20180125112A1

公开(公告)日：2018-05-10

申请号：US15786752

申请日：2017-10-18

Applicant: NAINAR AMALAN PRADEEP JEYAPRAKASH

Inventor： NAINAR AMALAN PRADEEP JEYAPRAKASH

IPC: A23P10/30 ,  B01J13/18 ,  B01J13/04 ,  B01J13/20 ,  A23L17/60 ,  C12G3/04 ,  A23L27/40 ,  A23L29/262 ,  A23L29/30

CPC classification number: A23P10/30 ,  A23L17/60 ,  A23L27/40 ,  A23L29/262 ,  A23L29/30 ,  A23V2002/00 ,  B01J13/043 ,  B01J13/18 ,  B01J13/20 ,  B01J13/22 ,  C12G3/04

Abstract: A composition with anti-snorting properties comprising a liquid based formulation, a marine seaweed extract, a plurality of salts, cellulose, carbohydrate and a plurality of additives.

公开(公告)号：US20180110685A1

公开(公告)日：2018-04-26

申请号：US15712478

申请日：2017-09-22

Applicant: ELC MANAGEMENT LLC

Inventor： Wilson A. Lee

IPC: A61K8/02 ,  A61K8/11 ,  C11D3/50 ,  A61Q13/00 ,  B01J13/02

CPC classification number: A61K8/0241 ,  A61K8/0279 ,  A61K8/11 ,  A61K8/894 ,  A61K2800/412 ,  A61K2800/56 ,  A61K2800/624 ,  A61L9/046 ,  A61Q13/00 ,  B01J13/02 ,  B01J13/043 ,  C11D3/373 ,  C11D3/502 ,  C11D3/505 ,  C11D17/0017 ,  C11D17/0039

Abstract: A delayed release delivery system comprises a hydrophilic core particle having surface pores and containing a liquid. The particle is encapsulated in a polymer having a hydrophobic backbone and hydrophilic pendant groups. At least some of the surface pores adjacent the hydrophilic pendant groups are blocked in the presence of water and unblocked in the absence of water. The treated particle contains liquid in a weight ratio of the liquid to the porous core particle of at least 400:1.

公开(公告)号：US20180072624A1

公开(公告)日：2018-03-15

申请号：US15562111

申请日：2016-03-30

Applicant: SHENZHEN UNIVERSITY

Inventor： Biqin DONG

IPC: C04B24/38 ,  C04B22/14 ,  C04B24/26 ,  C04B28/02 ,  C04B14/06 ,  B01J13/04

CPC classification number: C04B24/383 ,  B01J13/043 ,  C04B14/06 ,  C04B20/1033 ,  C04B20/1048 ,  C04B22/148 ,  C04B24/2676 ,  C04B28/02 ,  C04B2111/2038 ,  C04B2111/34 ,  C04B24/08 ,  C04B24/281 ,  C04B40/0641 ,  C04B7/323

Abstract: Disclosed are a microcapsule for self-healing concrete and a preparation method thereof, and a self-healing concrete and a preparation method thereof. The microcapsule comprises a core and a wall, the components of the core comprising a healing agent, microcrystalline cellulose and Tween 80, and a material of the wall being a high-molecular organic material sensitive to stress of cracks. The preparation method for the self-healing concrete comprises steps of: weighing appropriate amounts of cement, sand, water and the above microcapsules, with each cubic meter of concrete containing 0.05 to 0.08 cubic meter of the microcapsules; stirring the cement, sand and microcapsules until uniformly dispersed to obtain a mixture; and pouring the water into the mixture, and stirring uniformly.

公开(公告)号：US20170143597A1

公开(公告)日：2017-05-25

申请号：US15108944

申请日：2015-04-30

Applicant: KPT LTD.

Inventor： Yanfu JIANG ,  Ik Joo LEE ,  Woon Jang LEE ,  Byung-ho PARK ,  Jae Uk LEE

IPC: A61K8/11 ,  A61K8/34 ,  A61K8/73 ,  A61K8/25 ,  B01J13/04 ,  A61K8/55 ,  A61K8/81 ,  A61Q1/02 ,  A61Q19/00 ,  A61K8/02 ,  A61K8/29

CPC classification number: A61K8/11 ,  A61K8/025 ,  A61K8/0279 ,  A61K8/25 ,  A61K8/29 ,  A61K8/345 ,  A61K8/553 ,  A61K8/731 ,  A61K8/732 ,  A61K8/8147 ,  A61K8/8152 ,  A61K2800/41 ,  A61K2800/412 ,  A61K2800/621 ,  A61K2800/622 ,  A61K2800/624 ,  A61K2800/63 ,  A61K2800/651 ,  A61K2800/652 ,  A61K2800/654 ,  A61Q1/02 ,  A61Q19/00 ,  B01J13/04 ,  B01J13/043 ,  B01J13/046 ,  B01J13/22

Abstract: The instant invention relates to a composition for cosmetic raw material containing microcapsule containing at least one encapsulated material comprising at least one core and at least one layered coating surrounding the core, and the encapsulated material being at least one particle having a high wet point and being optionally porous, and being only released from the microcapsule when the composition is applied onto a keratin material, such as keratin fibers or skin. The invention further relates to a method for preparing the composition for cosmetic raw material containing microcapsule containing at least one encapsulated material comprising at least one core and at least one layered coating surrounding the core, and the encapsulated material being at least one particle having a high wet point and being optionally porous, and being only released from the microcapsule when the composition is applied onto a keratin material, such as keratin fibers or skin.

公开(公告)号：US20160361260A1

公开(公告)日：2016-12-15

申请号：US15249195

申请日：2016-08-26

Applicant: Pacira Pharmaceuticals, Inc.

Inventor： Ernest George Schutt ,  Ronald Warren McGuire ,  Peter Andrew Walters ,  Kathleen D.A. Los

IPC: A61K9/127 ,  B01F3/04 ,  B01F15/06 ,  A61K31/445

CPC classification number: A61K9/1271 ,  A61K9/127 ,  A61K9/1277 ,  A61K9/4833 ,  A61K31/445 ,  A61K31/4458 ,  A61M11/00 ,  B01D1/16 ,  B01F3/04049 ,  B01F3/0807 ,  B01F3/088 ,  B01F5/104 ,  B01F7/0075 ,  B01F15/065 ,  B01F2015/061 ,  B01F2215/0032 ,  B01J13/043 ,  B01J13/125

Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.

公开(公告)号：US09511341B2

公开(公告)日：2016-12-06

申请号：US14014823

申请日：2013-08-30

Applicant: SCI Pharmtech, Inc.

Inventor： Yen-Chih Lin ,  Yon-Lian Wu

IPC: B01J13/04 ,  A61K9/00

CPC classification number: B01J13/043 ,  A61K9/0019 ,  B01J13/04

Abstract: A method for preparing acetazolamide sodium powder for injection is provided. The method includes steps of providing an acetazolamide sodium solution; and aseptically spray drying the acetazolamide sodium solution to obtain the acetazolamide sodium powder.

Abstract translation: 提供了一种制备用于注射的乙酰唑胺钠粉末的方法。 该方法包括提供乙酰唑胺钠溶液的步骤; 并无菌喷雾干燥乙酰唑胺钠溶液，得到乙酰唑胺钠粉末。