公开(公告)号：US09383309B2

公开(公告)日：2016-07-05

申请号：US14845997

申请日：2015-09-04

Applicant: THERMO ELECTRON SCIENTIFIC INSTRUMENTS LLC

Inventor： John Magie Coffin

IPC: G01N1/10 ,  G01N21/35 ,  G01J3/02 ,  G01N21/03 ,  G01N21/15

CPC classification number: G01N21/35 ,  G01J3/0237 ,  G01N21/0303 ,  G01N21/15 ,  G01N2201/0668

Abstract: The present invention is thus directed to an automated system of varying the optical path length in a sample that a light from a spectrophotometer must travel through. Such arrangements allow a user to easily vary the optical path length while also providing the user with an easy way to clean and prepare a transmission cell for optical interrogation. Such path length control can be automatically controlled by a programmable control system to quickly collect and stores data from different path lengths as needed for different spectrographic analysis. Moreover, the system utilizes configured wedge shaped windows to best minimize the reflections of light which cause periodic variation in transmission at different wave lengths (commonly described as “channel spectra”). Such a system, as presented herein, is able to return best-match spectra with far fewer computational steps and greater speed than if all possible combinations of reference spectra are considered.

公开(公告)号：US09291551B2

公开(公告)日：2016-03-22

申请号：US14314603

申请日：2014-06-25

Applicant: DAINIPPON SCREEN MFG. CO., LTD.

Inventor： Sanzo Moriwaki ,  Hiroki Fujimoto

IPC: G01N21/25 ,  G01N21/47

CPC classification number: G01N21/255 ,  G01N21/47 ,  G01N2201/064 ,  G01N2201/0668

Abstract: An imaging apparatus for imaging a two-dimensional image of an imaging object comprises a holder which holds a sample container carrying a biological sample as the imaging object on a carrying surface, a light emitting part which emits light toward the carrying surface, an imager which includes a strip-like light receiving part, receives the light incident on the light receiving part and thereby images an image of a strip-like region of the carrying surface, a strip-like light shield which shields a part of light emitted from the illuminator toward the strip-like region, and a mover which integrally and relatively moves the light emitting part, the light receiving part and the light shield with respect to the sample container.

Abstract translation: 用于对成像对象的二维图像进行成像的成像装置包括：保持器，其将携带作为成像对象的生物样本的样本容器保持在承载表面上;发光部件，朝着承载表面发射光;成像器， 包括条状光接收部分，接收入射在光接收部分上的光，从而对承载表面的条状区域的图像进行成像;带状遮光罩，其屏蔽从照射器发出的光的一部分 朝向条状区域，以及使发光部，光接收部和遮光板相对于样本容器一体地移动的动子。

公开(公告)号：US20150116709A1

公开(公告)日：2015-04-30

申请号：US14397426

申请日：2013-04-26

Applicant: UNIVERSIDADE DE AVEIRO ,  INSTITUTO DE TELECOMMUNICAÇÕES

Inventor： Lúcia Maria Botas Bilro ,  Ricardo Xavier Da Graça Ferreira ,  Jan Jacob Keizer ,  Sérgio Prats Alegre ,  Rogério Nunes Nogueira

IPC: G01N21/53

CPC classification number: G01N21/53 ,  G01N21/532 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/0668 ,  G01N2201/08

Abstract: The present invention describes a low-cost, portable multi-parameter, turbidity sensor based on optical fiber.The sensor quantifies the transmission and scattering of radiation (nephelometry) in a fluid through radiation emission in two or more wavelengths. Inc invention can be used to estimate concentration of suspended sediments, to distinguish the type of sediment based on color, to distinguish different particle-size classes, and to identify and determine the concentrations of different suspended-sediment fractions.The sensor comprises the following elements: radiation emitter of two or more wavelengths (2), a radiation receiver to measure the transmitted radiation. (2), a radiation receiver to measure the scattered radiation (3), and an inner space (4) of the measurement unit containing the fluid being evaluated. The it three elements are located at the specified distances L1, L2 and L3, and at specified angles A1 and A2, as shown in the Figure

Abstract translation: 本发明描述了一种基于光纤的低成本便携式多参数浊度传感器。 传感器通过两个或更多波长的辐射发射量化流体中辐射（比浊法）的透射和散射。 本发明可用于估计悬浮沉积物的浓度，以区分基于颜色的沉积物的类型，以区分不同的粒度等级，并鉴定和确定不同悬浮沉积物组分的浓度。 传感器包括以下元件：两个或多个波长的辐射发射器（2），用于测量透射辐射的辐射接收器。 （2），用于测量散射辐射（3）的辐射接收器和包含被评估的流体的测量单元的内部空间（4）。 其三个元件位于指定的距离L1，L2和L3处，并且在指定的角度A1和A2处，如图所示

公开(公告)号：US08452365B2

公开(公告)日：2013-05-28

申请号：US11920599

申请日：2006-05-24

Applicant: Mihailo V. Rebec ,  Michael P. Houlne

Inventor： Mihailo V. Rebec ,  Michael P. Houlne

IPC: A61B5/00

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/14546 ,  A61B2562/0238 ,  G01N21/65 ,  G01N21/658 ,  G01N2201/0668

Abstract: A non-invasive method of determining the concentration of an analyte uses Raman spectral information. A high-intensity, narrow band of light (10) is applied to one side (12a) of skin tissue (12). The high-intensity light (10) enters the skin tissue and generates a Raman signal (16). A reflective material (22) is placed in a location nearest the other side (12b) of skin tissue (12). The reflective material (22) is located generally opposite of the entry (A) of the applied high-intensity light (10). The high-intensity light (10) and the Raman signal (20) that pass through the skin tissue (12) are reflected back into the skin tissue (12) via the reflective material (22). The Raman signal (16,20) is collected and the analyte concentration is determined using the collected Raman signal (16,20).

Abstract translation: 确定分析物浓度的非侵入性方法使用拉曼光谱信息。 将高强度，窄带光（10）施加到皮肤组织（12）的一侧（12a）。 高强度光（10）进入皮肤组织并产生拉曼信号（16）。 反射材料（22）被放置在最接近皮肤组织（12）的另一侧（12b）的位置。 反射材料（22）大致与施加的高强度光（10）的入口（A）相对。 穿过皮肤组织（12）的高强度光（10）和拉曼信号（20）经由反射材料（22）反射回皮肤组织（12）。 收集拉曼信号（16,20），并使用收集的拉曼信号（16,20）确定分析物浓度。

公开(公告)号：US07796265B2

公开(公告)日：2010-09-14

申请号：US12109254

申请日：2008-04-24

Applicant: Michael Tkachuk

Inventor： Michael Tkachuk

IPC: G01N21/00

CPC classification number: G01N21/3504 ,  G01N2201/0662 ,  G01N2201/0668

Abstract: An optical absorption gas analyzer for determining the concentration of a target gas in a sample is disclosed. The analyzer comprises a chamber for containing the sample in use; a radiation source assembly arranged to emit radiation into the chamber; a first radiation detector assembly arranged to detect radiation transmitted along a first optical path through the chamber and a second radiation detector assembly arranged to detect radiation transmitted along a second optical path through the chamber, wherein the length of the second optical path which the sample can intercept is shorter than that of the first optical path. The analyzer further comprises a processor adapted to generate a sensing signal SS based on the detected radiation transmitted along the first optical path and a reference signal SR based on the detected radiation transmitted along the second optical path. The processor determines the concentration of the target gas in the sample based on a comparison of the sensing signal with the reference signal.

Abstract translation: 公开了一种用于测定样品中目标气体浓度的光吸收气体分析仪。 分析仪包括用于容纳使用中的样品的室; 辐射源组件，被布置成将辐射发射到所述腔室中; 第一辐射检测器组件，被布置成检测沿着通过所述室的第一光路传输的辐射;以及第二辐射检测器组件，其布置成检测沿着通过所述室的第二光路传输的辐射，其中所述样品可以 截距比第一光路的截距短。 分析器还包括处理器，其适于基于沿着第一光路传输的检测到的辐射和基于沿着第二光路传输的检测到的辐射的参考信号SR生成感测信号SS。 处理器基于感测信号与参考信号的比较来确定样品中目标气体的浓度。

公开(公告)号：US20090177052A1

公开(公告)日：2009-07-09

申请号：US11920599

申请日：2006-05-24

Applicant: Mihailo V. Rebec ,  Michael P. Houlne

Inventor： Mihailo V. Rebec ,  Michael P. Houlne

IPC: A61B5/1455

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/14546 ,  A61B2562/0238 ,  G01N21/65 ,  G01N21/658 ,  G01N2201/0668

Abstract: A non-invasive method of determining the concentration of an analyte uses Raman spectral information. A high-intensity, narrow band of light (10) is applied to one side (12a) of skin tissue (12). The high-intensity light (10) enters the skin tissue and generates a Raman signal (16). A reflective material (22) is placed in a location nearest the other side (12b) of skin tissue (12). The reflective material (22) is located generally opposite of the entry (A) of the applied high-intensity light (10). The high-intensity light (10) and the Raman signal (20) that pass through the skin tissue (12) are reflected back into the skin tissue (12) via the reflective material (22). The Raman signal (16,20) is collected and the analyte concentration is determined using the collected Raman signal (16,20).

Abstract translation: 确定分析物浓度的非侵入性方法使用拉曼光谱信息。 将高强度，窄带光（10）施加到皮肤组织（12）的一侧（12a）。 高强度光（10）进入皮肤组织并产生拉曼信号（16）。 反射材料（22）被放置在最接近皮肤组织（12）的另一侧（12b）的位置。 反射材料（22）大致与施加的高强度光（10）的入口（A）相对。 穿过皮肤组织（12）的高强度光（10）和拉曼信号（20）经由反射材料（22）反射回皮肤组织（12）。 收集拉曼信号（16,20），并使用收集的拉曼信号（16,20）确定分析物浓度。

公开(公告)号：US20060119851A1

公开(公告)日：2006-06-08

申请号：US10525850

申请日：2002-09-06

Applicant: Fabrice Bounaix

Inventor： Fabrice Bounaix

IPC: G01N21/61

CPC classification number: G01N21/61 ,  G01N21/031 ,  G01N2201/0668

Abstract: A method and device for measuring a concentration of a preselected gas in a gas sample are disclosed. The device comprises a Herriott type multipass cell (10) having a center axle (74) and a housing (80A, 80B) surrounding and spaced from the axle to provide a tubular sample cavity (84). The gas sample is pumped through the sample cavity via apertures (154, 156) provided in opposed ends of the axle. A first mirror (44) and a second mirror (46) are supported at opposed ends of the axle. A light source, e.g. a laser or LED, is provided for emitting a light beam into the sample cavity via an entry aperture (30) in the first mirror, the light beam having a wave length at which the preselected gas strongly absorbs. The beam is reflected between the mirrors for a number of times before exiting the cell via an exit aperture (48) in the second mirror and impinging on a detector (52). The device further comprises a reference detector (32) for monitoring the intensity of the unattenuated light beam and a detector for detecting the intensity of light transmitted through the second mirror after a single pass through the cell. The light source is operatively connected to a heat control assembly having a heat sink and the gas sample is passed said heat sink to augment temperature control of the light source.

Abstract translation: 公开了一种用于测量气体样品中预选气体浓度的方法和装置。 该装置包括具有中心轴（74）的赫里奥多型多通道电池（10）和围绕轴并与轴间隔开的壳体（80A，80B），以提供管状样品腔（84）。 气体样品通过设置在轴的相对端的孔（154,156）泵送通过样品腔。 第一反射镜（44）和第二反射镜（46）被支撑在轴的相对端。 光源，例如 提供激光器或LED，用于经由第一反射镜中的入口孔（30）将光束发射到样品腔中，所述光束具有预定气体强吸收的波长。 光束在反射镜之间反射多次，然后经由第二反射镜中的出射孔（48）离开单元并撞击检测器（52）。 该装置还包括用于监测未衰减的光束的强度的参考检测器（32）和用于在单次通过电池之后检测透过第二反射镜的光的强度的检测器。 光源可操作地连接到具有散热器的热控制组件，并且气体样品通过所述散热器以增加光源的温度控制。

公开(公告)号：US5488227A

公开(公告)日：1996-01-30

申请号：US320674

申请日：1994-10-11

Applicant: Christopher R. Sweet

Inventor： Christopher R. Sweet

IPC: G01N21/03 ,  G01N21/61

CPC classification number: G01N21/031 ,  G01N2201/0668

Abstract: A gas analyser and detector has an infra red source, a gas chamber and a detector cell; the detector cell has a gas sample inlet, inlet and exit paths for an infra red beam and reflector means in the chamber comprising a convex surface and a concave surface. The reflector means ensures a long path length for the beam whilst reducing beam divergence and signal loss.

Abstract translation: 气体分析仪和检测器具有红外源，气室和检测器单元; 检测器单元具有气体样品入口，用于红外线的入口和出口路径以及腔室中的反射器装置，包括凸面和凹面。 反射器装置确保了光束的长路径长度，同时减少了光束发散和信号损失。

公开(公告)号：US12117389B2

公开(公告)日：2024-10-15

申请号：US17487722

申请日：2021-09-28

Applicant: Cytiva Sweden AB

Inventor： Henrik Svanberg ,  Hanno Ehring ,  Erik Nils Ostlund

IPC: G01N21/05 ,  G02B6/36 ,  G02B6/38 ,  G02B6/42

CPC classification number: G01N21/05 ,  G02B6/3616 ,  G02B6/3644 ,  G02B6/3825 ,  G02B6/3861 ,  G02B6/4219 ,  G01N2021/052 ,  G01N2201/0664 ,  G01N2201/0668 ,  G01N2201/0813 ,  G01N2201/086 ,  G02B6/36

Abstract: The present invention relates to an optical flow cell for a measuring device, having an input light guide with a light exit surface, an output light guide with a light entrance surface, said input light guide and output light guide being integrated with a holder to form an optical flow cell, and wherein the holder extends along a first axis and has a through hole for receiving a flow of a sample fluid, said through hole being transversal to said first axis, and the input light guide and output light guide further are arranged in said holder so that the light exit surface and the light entrance surface extend into said through hole and are arranged to be in optical alignment with each other and at a first distance from each other. The invention also relates to a measuring device having at least one optical flow cell.

公开(公告)号：US11953486B2

公开(公告)日：2024-04-09

申请号：US17628229

申请日：2020-07-19

Applicant: SENSIRION AG

Inventor： Raffaele Di Giacomo ,  Matthias Streiff ,  Michael Merz ,  Nicolas Moeller

IPC: G01N33/18 ,  G01N21/03 ,  G01N21/33 ,  G01N21/35

CPC classification number: G01N33/1846 ,  G01N21/03 ,  G01N21/33 ,  G01N21/35 ,  G01N2201/0668

Abstract: The present invention relates to a sensor (1) for sensing organic carbon in a liquid (L), comprising: a container (2) having an interior space (20) for receiving the liquid (L), a photodetector (3), and a light source (4) configured to emit ultraviolet light (5) so that the ultraviolet light (5) travels along an optical path (P) through liquid (L) residing in the interior space (20) and is absorbable by carbon bonds of organic molecules in the liquid (L). According to the present invention, the photodetector (3) is configured to detect light in the visible or infrared spectrum, and the sensor (1) comprises a down conversion material portion (22; 22a) arranged in the optical path, wherein the down conversion material portion (22; 22a) is configured to receive incoming ultraviolet light (5) emitted by the light source (4) and to down convert received ultraviolet light (5) and to emit said down converted light (50) in the visible or infrared spectrum so that emitted down converted light (50) impinges on the photodetector (3).