公开(公告)号：US09696263B2

公开(公告)日：2017-07-04

申请号：US14930069

申请日：2015-11-02

Applicant: THE BOEING COMPANY

Inventor： Michael J. Schaffer

IPC: G01J1/10 ,  G01N21/93 ,  G01N21/88

CPC classification number: G01N21/93 ,  G01N21/8803 ,  G01N21/954 ,  G01N2201/13 ,  G02B27/62

Abstract: A borescope calibration device is provided that includes a base having a planar surface and a plurality of reference surfaces on a side of the base opposing the planar surface, each of the plurality of reference surfaces having a height that decreases along a length of the base, a fixture that positions an optical head along a reference line that is parallel to the planar surface and providing a fixed distance between the reference surfaces and the optical head, the fixture being movable along a length of the base, and a target pattern formed on each of the reference surfaces.

公开(公告)号：US20170146448A1

公开(公告)日：2017-05-25

申请号：US14945691

申请日：2015-11-19

Applicant: International Business Machines Corporation

Inventor： William M. Green ,  Lionel Tombez ,  Eric Zhang

IPC: G01N21/27 ,  G01N33/00

CPC classification number: G01N21/27 ,  G01N21/274 ,  G01N21/3504 ,  G01N21/39 ,  G01N33/0047 ,  G01N2021/1748 ,  G01N2201/13

Abstract: Provided herein are techniques for improved optical absorption measurements in the presence of time-varying etalons. In one aspect, a method for dynamic etalon fitting for adaptive background noise reduction in an optical sensor is provided. The method includes the steps of: obtaining a zero-gas spectrum measured using the optical sensor; obtaining an analyte gas spectrum of a target trace gas measured using the optical sensor; comparing the zero-gas spectrum and the analyte gas spectrum using fit parameters that compensate for drifting etalons in the optical sensor; and dynamically extracting the drifting etalons from the analyte gas spectrum to retrieve concentration of the target trace gas.

公开(公告)号：US20170138854A1

公开(公告)日：2017-05-18

申请号：US15350337

申请日：2016-11-14

Applicant: GAMMON TECHNICAL PRODUCTS, INC.

Inventor： James H. Gammon ,  Michael Leggiero ,  David Fetzer

IPC: G01N21/64 ,  G01N33/22

CPC classification number: G01N33/22 ,  G01N21/77 ,  G01N2021/7786 ,  G01N2201/13

Abstract: A kit and method for manufacturing a reference standard for a water detection unit includes a substrate and a tray configured to receive the substrate therein. A tank is configured to receive at least one of the trays therein, wherein a fluorescent solution comprising water and uranine is provided to the tank via an inlet. The solution rises within the tank to saturate the substrate. The trays are then placed in a rotatable rack wherein the substrates are dried to remove excess solution. The dried substrates are then hermetically sealed within a transparent envelope.

公开(公告)号：US20170003216A1

公开(公告)日：2017-01-05

申请号：US14647100

申请日：2014-05-23

Applicant: SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD

Inventor： Li Wang

IPC: G01N21/33 ,  G01N1/38

CPC classification number: G01N21/33 ,  G01N1/38 ,  G01N2021/3155 ,  G01N2201/13

Abstract: The present invention discloses a method for measuring the concentration of a photoresist in a stripping liquid. In the method for measuring the concentration of a photoresist in a stripping liquid, a plurality of standard photoresist samples are prepared at first, then the spectrum of the standard photoresist samples and the spectrum of the test photoresist sample are collected, and the nth derivative of the spectrum of the standard photoresist samples and the spectrum of the test photoresist sample are taken, wherein n is an integer equal to or greater than 1, a standard curve based on the nth derivative curves and calculating the concentration of the test photoresist sample is established, the concentration of a photoresist in a stripping liquid can be measured accurately according to the standard curve.

Abstract translation: 本发明公开了一种测定汽提液中光致抗蚀剂浓度的方法。 在测定剥离液中的光致抗蚀剂浓度的方法中，首先制备多个标准光致抗蚀剂样品，然后收集标准光致抗蚀剂样品的光谱和测试光致抗蚀剂样品的光谱，并且将第 拍摄标准光致抗蚀剂样品的光谱和测试光致抗蚀剂样品的光谱，其中n是等于或大于1的整数，建立基于第n个导数曲线并计算测试光致抗蚀剂样品的浓度的标准曲线 可以根据标准曲线精确地测量剥离液中的光致抗蚀剂的浓度。

公开(公告)号：US09506855B2

公开(公告)日：2016-11-29

申请号：US14376324

申请日：2013-02-04

Applicant: University of Cincinnati ,  The United States of America as Represented by the Secretary of the Air Force

Inventor： Ian Papautsky ,  Li Shen ,  Joshua Hagen ,  Morley Stone

IPC: G01N21/25 ,  G01J3/46 ,  G01N21/27 ,  G01N21/78 ,  G01N21/29

CPC classification number: G01N21/25 ,  G01J3/46 ,  G01N21/278 ,  G01N21/293 ,  G01N21/78 ,  G01N2201/061 ,  G01N2201/127 ,  G01N2201/13

Abstract: Described herein is a method, system and computer program for analyzing a colorimetric assay that includes obtaining an image of the assay, optionally correcting for ambient lighting conditions in the image, converting the intensity data for at least one of the red channel, the green channel, or the blue channel to a first data point, recalling a predetermined standardized curve, comparing the first data point with the standardized curve, and identifying the value for the assay parameter from the standardized curve.

Abstract translation: 本文描述了一种用于分析比色测定法的方法，系统和计算机程序，其包括获得测定图像，可选地校正图像中的环境光照条件，转换红色通道，绿色通道中的至少一个的强度数据 或蓝色通道移动到第一数据点，回忆预定的标准化曲线，将第一数据点与标准化曲线进行比较，并从标准化曲线识别测定参数的值。

公开(公告)号：US09439587B2

公开(公告)日：2016-09-13

申请号：US14703312

申请日：2015-05-04

Applicant: Roche Diabetes Care, Inc.

Inventor： Karl Miltner ,  Robert Lorenz ,  Ulrich Porsch ,  Clemens Knapp

IPC: G01N21/77 ,  A61B5/145 ,  A61B5/1455

CPC classification number: G01N21/8483 ,  A61B5/14532 ,  A61B5/1455 ,  A61B2560/0223 ,  A61B2562/0295 ,  G01N35/00009 ,  G01N2021/8488 ,  G01N2021/8494 ,  G01N2035/0491 ,  G01N2201/062 ,  G01N2201/13

Abstract: There is provided a test method for analyzing a body fluid in which a test tape is used in a test device to successively provide analytical test fields stored on the test tape, wherein body fluid is applied by a user to the test field provided at a time and the said test field is photometrically scanned using a measuring unit of the device to record measurement signals. To increase the measurement reliability, it is proposed that a control value is determined from a time-dependent and/or wavelength-dependent change in the measurement signals and that the measurement signals are processed as valid or discarded as erroneous depending on the control value.

Abstract translation: 提供了一种用于分析体液的测试方法，其中在测试装置中使用测试带，以连续提供存储在测试带上的分析测试领域，其中体液被用户施加到一次提供的测试场 并且使用该装置的测量单元对所述测试场进行光度扫描以记录测量信号。 为了提高测量可靠性，提出根据测量信号的时间依赖性和/或波长相关的变化确定控制值，并且根据控制值将测量信号处理为有效或被丢弃为错误。

公开(公告)号：US20150355092A1

公开(公告)日：2015-12-10

申请号：US14738134

申请日：2015-06-12

Applicant: OLYMPUS CORPORATION

Inventor： Mitsushiro YAMAGUCHI

IPC: G01N21/64 ,  G01M11/00

CPC classification number: G01N21/645 ,  G01M11/00 ,  G01M11/02 ,  G01N21/274 ,  G01N21/276 ,  G01N21/278 ,  G01N21/6458 ,  G01N2201/06113 ,  G01N2201/127 ,  G01N2201/13 ,  G02B21/0076 ,  G02B21/008 ,  G02B21/34

Abstract: An optical system of an optical analysis device is easily evaluated with high accuracy.There is provided a method of evaluating an optical analysis device including an optical system A capable of forming a confocal volume C at a focal position by condensing excitation light B, the method including the steps of: placing, at the focal position of the optical system A, a phantom sample in which two or more types of solid members having different fluorescent substance concentrations are arranged adjacent to each other; irradiating the phantom sample 1 with excitation light through the optical system A while relatively moving the confocal volume C formed by the optical system A and the phantom sample in an arrangement direction of the solid members; detecting fluorescent light generated in the solid members placed in the confocal volume C; and evaluating the optical system A based on the detected fluorescent light.

Abstract translation: 光学分析装置的光学系统容易以高精度进行评估。 本发明提供了一种光学分析装置的评估方法，该光学分析装置包括能够通过聚焦激发光B在聚焦位置形成共焦体积C的光学系统A，该方法包括以下步骤：在光学系统的焦点位置 A，其中具有不同荧光物质浓度的两种或更多种类型的固体成分相互排列的幻影样品; 通过光学系统A照射假想样品1，同时在固体构件的排列方向上相对移动由光学系统A和体模样品形成的共焦体积C; 检测在共焦体积C中的固体成分中产生的荧光; 以及基于检测到的荧光来评估光学系统A.

公开(公告)号：US08928885B1

公开(公告)日：2015-01-06

申请号：US14503901

申请日：2014-10-01

Applicant: Beijing Information Science & Technology University

Inventor： Fei Luo ,  Lianqing Zhu ,  Mingli Dong ,  Wei He ,  Yinmin Zhang

IPC: G01N21/61 ,  G01N21/27

CPC classification number: G01N21/3504 ,  G01N2201/06113 ,  G01N2201/13

Abstract: A gas detection system using a semiconductor laser with a reference gas cavity compensation is provided, said system comprising a first light source emitting a first beam of a first wavelength as a detection beam; a second light source emitting a second beam of a second wavelength, which is different from the first wavelength, as a reference beam; a first wavelength division multiplexer connected with said first light source and said second light source; a broadband coupler connected with said first wavelength division multiplexer; a reference gas chamber, which is introduced with reference gas of the same composition as that of the gas to be detected and of a known concentration; a detection gas chamber, which is introduced with the gas to be detected.

Abstract translation: 提供了一种使用具有参考气腔补偿的半导体激光器的气体检测系统，所述系统包括发射第一波长的第一光束作为检测光束的第一光源; 发射与第一波长不同的第二波长的第二光束作为参考光束的第二光源; 与所述第一光源和所述第二光源连接的第一波分多路复用器; 与所述第一波分多路复用器连接的宽带耦合器; 参考气体室，其被引入具有与待检测气体相同组成的参考气体并具有已知浓度; 检测气体室，其被引入待检测的气体。

公开(公告)号：US20140353503A1

公开(公告)日：2014-12-04

申请号：US14241647

申请日：2012-08-31

Applicant: Maureen Lanan ,  Amr Ali

Inventor： Maureen Lanan ,  Amr Ali

IPC: G01N21/35 ,  G01N33/50 ,  G01R33/48 ,  G01N24/08

CPC classification number: G01N21/359 ,  G01N24/087 ,  G01N33/50 ,  G01N2201/12 ,  G01N2201/13 ,  G01R33/4625 ,  G01R33/465 ,  G01R33/4808 ,  G06F19/703 ,  G06F19/707

Abstract: In one aspect, the disclosure provides methods for using NMR and NIR to evaluate biological samples. In some embodiments, the methods include a step of performing a Nuclear Magnetic Resonance (NMR) analysis on a sample to obtain an NMR spectrum, a step of performing a Near Infrared Spectroscopy (NIR) analysis on the sample to obtain an NIR spectrum, and/or a step of performing a data fusion analysis to evaluate the NIR spectrum.

Abstract translation: 一方面，本公开提供了使用NMR和NIR来评估生物样品的方法。 在一些实施方案中，所述方法包括对样品进行核磁共振（NMR）分析以获得NMR光谱的步骤，对样品进行近红外光谱（NIR）分析以获得NIR光谱的步骤，以及 /或执行数据融合分析以评估NIR光谱的步骤。

公开(公告)号：US20120123688A1

公开(公告)日：2012-05-17

申请号：US13234947

申请日：2011-09-16

Applicant: Natarajan Ramasubramanyan ,  Li-Hong Malmberg ,  Martin Sternman

Inventor： Natarajan Ramasubramanyan ,  Li-Hong Malmberg ,  Martin Sternman

IPC: G06F19/00 ,  G01N21/65

CPC classification number: G01N21/65 ,  G01N33/6848 ,  G01N33/6854 ,  G01N2201/13

Abstract: A method of characterizing a multi-component mixture for use in a bioprocess operation that includes providing a multi-component mixture standard with pre-determined amounts of known components; performing a Raman Spectroscopy analysis on the multi-component mixture standard; providing a multi-component test mixture from the bioprocess operation; performing a Raman Spectroscopy analysis on the multi-component test mixture; and comparing the analysis of the multi-component mixture standard and the multi-component test mixture to characterize the multi-component test mixture. In one embodiment, the multi-component mixture standard and the multi-component test mixture both comprise one or more of, at least two, at least three of, or each of, a polysaccharide (e.g. sucrose or mannitol), an amino acid (e.g., L-arginine, L-histidine or L-ornithine), a surfactant (e.g. polysorbate 80) and a pH buffer (e.g., a citrate formulation).

Abstract translation: 一种表征用于生物过程操作的多组分混合物的方法，其包括提供具有预定量的已知组分的多组分混合物标准品; 对多组分混合物标准进行拉曼光谱分析; 从生物过程操作提供多组分测试混合物; 对多组分测试混合物进行拉曼光谱分析; 并比较多组分混合物标准品和多组分试验混合物的分析，以表征多组分试验混合物。 在一个实施方案中，多组分混合物标准品和多组分测试混合物都包含多糖（例如蔗糖或甘露糖醇），氨基酸（例如蔗糖或甘露醇）中的一种或多种，​​至少两种，至少三种， 例如L-精氨酸，L-组氨酸或L-鸟氨酸），表面活性剂（例如聚山梨酯80）和pH缓冲液（例如柠檬酸盐制剂）。