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公开(公告)号：US11103697B2
公开(公告)日：2021-08-31
申请号：US15388128
申请日：2016-12-22
Applicant: SPR Therapeutics, Inc.
Inventor： Joseph W. Boggs , Amorn Wongsarnpigoon , Matthew G. deBock , Meredith J. McGee , Devin Sell , Robert B. Strother
Abstract: An introducing device for locating a tissue region and deploying an electrode is shown and described. The introducing device may include an outer sheath. An inner sheath may be disposed within the outer sheath. The inner sheath may be configured to engage an implantable electrode. In an example, the inner sheath may comprise a stimulation probe having an uninsulated portion at or near a distal end of the delivery sheath. The outer sheath may be coupled to a power source or stimulation signal generating circuitry at a proximal end. A clinician may control application of the stimulation signal to a tissue region via the outer sheath.
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公开(公告)号：US11027123B2
公开(公告)日：2021-06-08
申请号：US16251482
申请日：2019-01-18
Applicant: SPR THERAPEUTICS, INC.
Inventor： Joseph W. Boggs , Rosemary H. Zang
Abstract: Systems and methods are provided for applying electrical stimulation to a body by an electrode spaced from a target nerve of passage. It has been discovered that pain felt, or perceived to be felt, in a given region of the body can be treated by stimulating muscle close to a “nerve of passage” in a region that is superior (i.e., cranial or upstream toward the spinal column) to the region where pain is felt, such as in a case of post-amputation residual limb pain, or purportedly felt in the case of post-amputation phantom limb pain.
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公开(公告)号：US20200230411A1
公开(公告)日：2020-07-23
申请号：US16842863
申请日：2020-04-08
Applicant: SPR Therapeutics, INC.
Inventor： Meredith McGee , Joseph W. Boggs , John Chae , Amorn Wongsarnpigoon , Maria E. Bennett
Abstract: The present invention reduces pain and improves function long-term in persons with back pain using electrical stimulation in the back. This approach involves an electrical stimulation device including at least one electrode adapted for insertion within an animal body with back pain and at least one pulse generator operatively coupled with the at least one electrode, wherein the pulse generator delivers electrical stimulation activating at least a nerve innervating at least a paraspinal muscle in a back of the animal body for pain relief.
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74.发明申请公开(公告)号：US20200030606A1
公开(公告)日：2020-01-30
申请号：US16587527
申请日：2019-09-30
Applicant: SPR Therapeutics, Inc.
Inventor： Joseph W. Boggs, II
Abstract: Systems and methods make possible the placement of one or more electrode leads in a tissue region for providing functional and/or therapeutic stimulation to tissue. The systems and methods are adapted to provide the relief of pain.
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75.发明申请公开(公告)号：US20190151660A1
公开(公告)日：2019-05-23
申请号：US16036992
申请日：2018-07-17
Applicant: SPR Therapeutics, Inc.
Inventor： Joseph W. Boggs, II , Nathan D. Crosby , Amorn Wongsarnpigoon
IPC: A61N1/36
Abstract: Pain felt in a given region of the body can be treated by stimulating a peripheral nerve at a therapeutically effective distance from the region where pain is felt to generate a comfortable sensation (i.e., paresthesia) overlapping the regions of pain. Systems and methods to reduce pain in a painful region following surgical amputation of an extremity or limb may include stimulating a peripheral nerve innervating the painful region with an electrode inserted into tissue and spaced from the peripheral nerve. This method may be used to help alleviate postoperative pain in patients following amputation of an extremity or limb.
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Patent Agency Ranking
76.发明申请公开(公告)号：US20190151650A1
公开(公告)日：2019-05-23
申请号：US16214277
申请日：2018-12-10
Applicant: SPR Therapeutics, Inc.
Inventor： Maria E. Bennett , Joseph W. Boggs, II , John Chae
Abstract: Systems and methods are provided for treating chronic pain occurring secondarily to subacromial impingement syndrome in a human body. A system is provided to deliver percutaneous electrical stimulation through at least one electrode to neurological motor points of the posterior and middle deltoid muscles to mediate such pain. One-time, continued and/or periodic dosing of treatment methods according to the present invention may result in a change to central nervous system maladaptive neuroplasticity.
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77.发明授权公开(公告)号：US10166384B2
公开(公告)日：2019-01-01
申请号：US15822580
申请日：2017-11-27
Applicant: SPR Therapeutics, Inc.
Inventor： Maria E. Bennett , Joseph W. Boggs, II , John Chae
Abstract: Systems and methods are provided for treating chronic pain occurring secondarily to subacromial impingement syndrome in a human body. A system is provided to deliver percutaneous electrical stimulation through at least one electrode to neurological motor points of the posterior and middle deltoid muscles to mediate such pain. One-time, continued and/or periodic dosing of treatment methods according to the present invention may result in a change to central nervous system maladaptive neuroplasticity.
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公开(公告)号：US20250121192A1
公开(公告)日：2025-04-17
申请号：US19002021
申请日：2024-12-26
Applicant: SPR Therapeutics, Inc.
Inventor： Maria E. Bennett , Joseph W. Boggs , Warren M. Grill , John Chae
IPC: A61N1/36
Abstract: Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
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公开(公告)号：US12194296B2
公开(公告)日：2025-01-14
申请号：US18079942
申请日：2022-12-13
Applicant: SPR Therapeutics, Inc.
Inventor： Joseph W. Boggs , Amorn Wongsarnpigoon , Matthew G. deBock , Nathan Crosby
Abstract: Device/system that provides pain relief by delivering stimulation that neither generates action potentials nor completely blocks neural transmission (in the peripheral nerve). The present teachings provide relief by modulating release of neurotransmitters in peripheral nerves to cause neuromodulation at the level of the peripheral nerve (modulation of neural signals in the peripheral nerve). The present teachings provide relief by modulating release of neurotransmitters in peripheral nerves to cause neuromodulation at the level of the peripheral nerve (modulation of neural signals in the peripheral nerve) to alter the frequency of physiologically generated neural transmission.
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公开(公告)号：US20240359021A1
公开(公告)日：2024-10-31
申请号：US18758026
申请日：2024-06-28
Applicant: SPR THERAPEUTICS, INC.
Inventor： Matthew G. DEBOCK , Joseph W. Boggs, II , Matthew J. WUNZIN , Robert B. STROTHER, JR. , Devin SELL , Mark R. STULTZ , Bradley A. LEWIS
IPC: A61N1/375 , A61N1/05 , A61N1/36 , H01R4/2433
CPC classification number: A61N1/3752 , A61N1/0529 , A61N1/36057 , A61N1/3758 , H01R4/2433 , H01R2201/12
Abstract: A connector assembly includes a base and a detachable cover. Ports on separate sidewalls receive an extension cable and a lead. A blade assembly maintains electrical contact between the cable and the lead, while providing a surface to strip insulation and/or sever the lead. Further, the blade is resilient so as to maintain sufficient contact with the lead when the cover is attached and/or locked to the base.
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