公开(公告)号：US2865303A

公开(公告)日：1958-12-23

申请号：US46386054

申请日：1954-10-22

Applicant: TECHNICON INSTR

Inventor： FERRARI JR ANDRES ,  JACK ISREELI

IPC: F04B43/12

CPC classification number: F04B43/1223

公开(公告)号：US2788681A

公开(公告)日：1957-04-16

申请号：US48164655

申请日：1955-01-13

Applicant: TECHNICON INSTR

Inventor： KLING NELSON G

IPC: F16H3/00 ,  G03B19/18

CPC classification number: F16H3/003 ,  G03B19/18 ,  Y10T74/19172

公开(公告)号：US3902052A

公开(公告)日：1975-08-26

申请号：US36849073

申请日：1973-06-11

Applicant: TECHNICON INSTR

Inventor： AMAR HENRY E ,  GRADY JOHN J

IPC: G01N33/48 ,  G01D1/00 ,  G01N33/49 ,  G01N35/00 ,  G08C25/00 ,  G06F15/20

CPC classification number: G01N35/00

Abstract: Method and apparatus are provided for determining the validity and maximizing the accuracy of analytical results provided by automated sample analysis apparatus which operate in accordance with ideal operational characteristics and wherein the analytical results are provided in the form of a series of data outputs for each sample analysis and comprise the constant monitoring of the data outputs produced by the apparatus upon the analysis of a sample, the comparison of the thusly monitored data outputs to determine the variations therebetween, the comparison of variations with said ideal operational characteristics of said apparatus so as to verify the validity of the thusly monitored data outputs, and the selection and outputting as the sample analysis results in accordance with said comparisons of those of said data outputs which are most analytically correct to thus maximize the accuracy of said results.

公开(公告)号：US3862010A

公开(公告)日：1975-01-21

申请号：US26150072

申请日：1972-06-09

Applicant: TECHNICON INSTR

Inventor： RUSH ROBERT L ,  DELEA ANNE C ,  STASTNY MILOS ,  LASH EDWARD D

IPC: C12N9/04 ,  C12Q1/32 ,  G01N31/14 ,  G01N33/16

CPC classification number: C12Q1/32

Abstract: A method of effectively heat fractionating lactic acid dehydrogenase-containing samples into their isoenzyme components to determine abnormal LDH activity for diagnostic purposes is disclosed which relates to a rapid heating step in the presence of a buffered solution having a certain concentration and carried out at a specified pH range.

Abstract translation: 公开了一种有效地将含乳酸脱氢酶的样品热分馏到其同工酶组分中以确定用于诊断目的的异常LDH活性的方法，其涉及在具有一定浓度的缓冲溶液存在下的快速加热步骤，并且在指定的 pH范围。

公开(公告)号：US3853465A

公开(公告)日：1974-12-10

申请号：US26149972

申请日：1972-06-09

Applicant: TECHNICON INSTR

Inventor： RUSH R ,  VLASTELICA D

IPC: G01N33/48 ,  G01N1/40 ,  G01N33/50 ,  G01N33/52 ,  G01N33/531 ,  G01N33/16 ,  B01F17/00 ,  C09K3/00

CPC classification number: G01N1/40 ,  G01N1/4044 ,  G01N33/50 ,  Y10T436/25

Abstract: WHEREIN N IS AN INTEGER FROM 9 TO 20, UNTIL IT BECOMES OPTICALLY CLEAR.

The reduction of turbidity in serum and plasma samples to be analyzed photometrically whereby the sample is mixed with a polyoxyethylated lauric acid compound of the formula:

Abstract translation: 将血浆和血浆样品中的浊度降低进行光度分析，由此将样品与下式的聚氧乙基化月桂酸化合物混合：

公开(公告)号：US3851826A

公开(公告)日：1974-12-03

申请号：US39692573

申请日：1973-09-13

Applicant: TECHNICON INSTR

Inventor： PERLMAN I

IPC: B01F7/16 ,  B01F3/08 ,  B01F13/10 ,  B02C18/06 ,  B02C18/10 ,  G01N1/28

CPC classification number: B02C18/10 ,  B01F13/1044 ,  G01N1/286

Abstract: A mixer to reduce solids having a constituent of interest therein for analysis, which reduction is of a physical nature and takes place in a carrier liquid. The mixer is similar to a homogenizer and includes a cutter element which rotates relatively to a second cutter element and is mounted to float toward and away from the second element. The first cutter element has at least one hydrofoil surface portion on the face thereof obverse to the face thereof which coacts with the second element. When the first cutter element is rotated at speed, the action of such hydrofoil surface on the carrier liquid is such as to urge the first cutter element toward the second cutter element to obtain the optimum cutting gap between the cutter elements.

Abstract translation: 用于减少具有其中关注成分的固体的混合器用于分析，该还原物理性质并发生在载体液体中。 混合器类似于均化器，并且包括相对于第二切割器元件旋转并且被安装成朝向和远离第二元件浮动的切割器元件。 第一切割元件具有与其与第二元件共同作用的其表面正面的至少一个水翼表面部分。 当第一切割元件以速度旋转时，这种水翼表面在载体液体上的作用是将第一切割元件推向第二切割元件以获得切割元件之间的最佳切割间隙。

公开(公告)号：US3847773A

公开(公告)日：1974-11-12

申请号：US36901673

申请日：1973-06-11

Applicant: TECHNICON INSTR

Inventor： SNYDER L

IPC: G01N27/447 ,  B01K5/00

CPC classification number: G01N27/44782 ,  G01N27/44756 ,  G01N27/44769

Abstract: A method and apparatus for curtain electrophoresis in which ionic species of a sample are separated by differential migration under the influence of an electric field gradient extending horizontally across a sheathed vertical curtain of a liquid medium. The sample enters the curtain, which includes buffer solution, adjacent the top of the curtain, and the sample fractions leave the curtain adjacent the bottom of the latter at different lateral locations with reference to the vertical center line of the curtain. The adverse effect of horizontal sample flow inequality on sample separation resolution, which inequality results in horizontal band broadening or spreading, is significantly reduced or eliminated. Such reduction is achieved by pulsing the electric field on and off in synchronization with the sample flow: the field is deenergized while the sample is entering the curtain and again while the sample is leaving the curtain.

Abstract translation: 一种用于帘式电泳的方法和装置，其中样品的离子种类在水平延伸穿过液体介质的护套垂直帘幕的电场梯度的影响下通过差分迁移分离。 样品进入窗帘，其包括缓冲溶液，邻近窗帘的顶部，并且样品部分参考帘幕的垂直中心线在不同的横向位置处离开窗帘邻近后部的底部。 水平采样流量不等式对样本分离分辨率的不利影响，这种不平等导致水平带宽扩大或扩展，显着降低或消除。 通过与样品流同步地脉冲地打开和关闭电场来实现这种减少：当样品进入窗帘时再次断开场，同时样品离开窗帘。

公开(公告)号：US3804593A

公开(公告)日：1974-04-16

申请号：US36969564

申请日：1964-05-25

Applicant: TECHNICON INSTR

Inventor： SMYTHE W ,  SHAMOS M

IPC: G01N35/08 ,  G01N31/00

CPC classification number: G01N35/08 ,  Y10T436/118339

Abstract: An automatic analysis apparatus includes an indexible table supporting a plurality of liquid sample containers, a stationary reagent liquid container, two off-take tubes, one tube insertable in a presented thereto sample container, the other tube insertable in the reagent container, means for concurrently inserting both tubes repeatedly into their respective containers to provide a flowing stream of segments of liquid sample interspersed by air segments, and a similar stream of segments of reagent. These streams are merged to form stream of liquid and air segments, which stream of liquid and air segments is passed through the sight passageway of a flow cell of a colorimeter. A recorder is coupled to the colorimeter, and may be rendered operational when the sight passageway of the flow cell is fully occupied by liquid.

Abstract translation: 一种自动分析装置，包括：支撑多个液体样品容器的可分度台，固定试液容器，两个取出管，可插入到样品容器中的一个管，可插入试剂容器中的另一个管，同时 将两个管重复插入其各自的容器中以提供由空气段散布的液体样品的段的流动流和类似的试剂段。 这些流合流以形成液体和空气段的流，该液流和空气流的流通过比色计的流动池的视线通道。 记录器耦合到色度计，并且当流动池的视线通道被液体完全占据时可以使其操作。

公开(公告)号：US3770405A

公开(公告)日：1973-11-06

申请号：US3770405D

申请日：1972-04-24

Applicant: TECHNICON INSTR

Inventor： DE ANGELIS W ,  LUTHMANN R ,  MEEHAN C ,  SMITH M

IPC: C03B23/20 ,  B01L3/00 ,  B01L99/00 ,  C03B19/00 ,  C03C27/00 ,  G01N35/08

CPC classification number: B01L3/561

Abstract: A method of fabricating laboratory glassware to provide a relatively small, rugged article of monolithic form having one or more relatively small fluid passageways therein which may be characterized as having the appearance of wormholes. The method includes the step of preforming sacrificial tubing, sections of which may be socketed together, and socketing the tubing with tubular connectors on assembly, prior to encapsulating the assembly in glass material. The sacrificial tubing is removed after encapsulation.

Abstract translation: 一种制造实验室玻璃器皿以提供具有一个或多个相对较小的液体通道的相对小的，坚固的整体式制品的方法，其可以被表征为具有虫洞的外观。 该方法包括在将组件封装在玻璃材料中之前预成型牺牲管的步骤，其部分可以套在一起，以及在组装时将管道连接在管状连接器上。 封装后去除牺牲管。

公开(公告)号：US3752443A

公开(公告)日：1973-08-14

申请号：US3752443D

申请日：1971-12-13

Applicant: TECHNICON INSTR

Inventor： LICHTENSTEIN B

IPC: G01N33/86 ,  B01F13/08 ,  G01N33/49 ,  G01N35/00 ,  G01N21/24

CPC classification number: B01F13/0809 ,  G01N33/4905 ,  G01N35/0098

Abstract: A magnetic mixer for laboratory use which includes a permanent magnet mounted for rotation and driven on an axis centrally between its poles. A volume of combined liquids, containing in addition a multiplicity of magnetic particles, is supported centrally with reference to the magnet poles for activation of the particles in the rotating magnetic field to mix the liquids to achieve a reaction between them or merely a blending. This rotational force on the mixture has the effect of redistributing the magnetic particles away from the center of the mixture which effect, unless countered, lessens the mixing action. A second permanent magnet is provided having its poles in substantial alignment with the first mentioned axis, and having one of these last-mentioned poles spaced a distance nearer to the mixture than the other pole thereof, the magnetic field of the second magnet being substantially at right angles to the magnetic field of the first magnet. The field of the second magnet effectively counters by attraction the aforementioned redistributing movement of the magnetic particles, and the resultant particle distribution is substantially uniform throughout the combined liquids.

Abstract translation: 一种用于实验室使用的磁力搅拌器，其包括永磁体，该永久磁铁安装成用于旋转并在轴之间的轴线上驱动。 另外还含有多个磁性颗粒的混合液体的量相对于用于激活旋转磁场中的颗粒的磁极被中心地支撑以混合液体以实现它们之间的反应或仅仅是混合。 混合物上的这种旋转力具有将磁性颗粒重新分布离开混合物中心的作用，除非有所反应，否则会降低混合作用。 提供第二永久磁铁，其极点与第一个提到的轴基本对齐，并且这些最后提到的磁极之一与其混合物的另一个极点相隔一定距离，第二磁体的磁场基本上位于 与第一磁体的磁场成直角。 第二磁体的场通过吸引上述磁性颗粒的再分布运动而有效地反应，并且所得到的颗粒分布在整个组合液体中基本上是均匀的。