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公开(公告)号:US20140332380A1
公开(公告)日:2014-11-13
申请号:US14338889
申请日:2014-07-23
Applicant: Advanced Liquid Logic, Inc.
Inventor: Ryan A. Sturmer , Michael G. Pollack , Vamsee K. Pamula , Vijay Srinivasan , Philip Y. Paik
IPC: B01L3/00
CPC classification number: B01L3/50273 , B01L3/502715 , B01L3/502784 , B01L2200/0605 , B01L2300/0627 , B01L2300/0636 , B01L2300/0645 , B01L2300/0809 , B01L2400/0427 , G01N27/22 , G01N27/223 , G01N27/227 , G01N2203/00 , G01V3/02
Abstract: A method, circuit and apparatus for detecting capacitance on a droplet actuator, inter alia, for determining the presence, partial presence or absence of a droplet at an electrode on a droplet actuator by: (a) providing a droplet actuator comprising: (i) a substrate comprising electrodes arranged on the substrate for conducting droplet operations on a surface of the substrate; (ii) a capacitance detection circuit for detecting capacitance at the droplet operations surface at one or more of the electrodes; (b) detecting capacitance at the droplet operations surface at one or more of the electrodes; and (c) determining from the capacitance the presence, partial presence or absence of a droplet at the droplet operations surface at the electrode.
Abstract translation: 一种用于检测液滴致动器上电容的方法,电路和装置,特别是用于通过以下步骤确定液滴致动器上的电极处的液滴的存在,部分存在或不存在:(a)提供液滴致动器,其包括:(i) 基板,其包括布置在所述基板上的电极,用于在所述基板的表面上进行液滴操作; (ii)电容检测电路,用于检测一个或多个电极处的液滴操作表面处的电容; (b)在一个或多个电极处检测液滴操作表面处的电容; 和(c)根据电容确定在电极处的液滴操作表面处的液滴的存在,部分存在或不存在。
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公开(公告)号:US20160114320A1
公开(公告)日:2016-04-28
申请号:US14935823
申请日:2015-11-09
Applicant: Duke University
Inventor: Michael G. Pollack , Vamsee K. Pamula , Richard B. Fair
IPC: B01L3/00 , G01N27/447
CPC classification number: B01L3/50273 , B01F11/0071 , B01F13/0071 , B01F13/0076 , B01F13/0084 , B01L3/00 , B01L3/5027 , B01L3/502784 , B01L3/502792 , B01L2200/06 , B01L2200/0605 , B01L2200/10 , B01L2300/089 , B01L2300/161 , B01L2300/165 , B01L2400/0415 , B01L2400/0427 , B41J2002/14395 , C25B9/00 , G01N27/44791 , G02B26/005
Abstract: Methods are provided for manipulating droplets. The methods include providing the droplet on a surface comprising an array of electrodes and a substantially co-planer array of reference elements, wherein the droplet is disposed on a first one of the electrodes, and the droplet at least partially overlaps a second one of the electrodes and an intervening one of the reference elements disposed between the first and second electrodes. The methods further include activating the first and second electrodes to spread at least a portion of the droplet across the second electrode and deactivating the first electrode to move the droplet from the first electrode to the second electrode.
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公开(公告)号:US20150336098A1
公开(公告)日:2015-11-26
申请号:US14817834
申请日:2015-08-04
Applicant: Duke University
Inventor: Michael G. Pollack , Vamsee K. Pamula , Richard B. Fair
IPC: B01L3/00
CPC classification number: G01N27/44769 , B01F13/0071 , B01F13/0076 , B01L3/502707 , B01L3/502792 , B01L7/52 , B01L2200/0673 , B01L2200/10 , B01L2200/12 , B01L2300/0645 , B01L2300/0663 , B01L2300/0819 , B01L2300/0864 , B01L2300/0867 , B01L2300/0887 , B01L2300/089 , B01L2300/12 , B01L2300/1827 , B01L2400/0415 , B01L2400/0424 , B81B3/0021 , B81B2201/058 , B81C1/00119 , C12Q1/6846 , G01N27/447 , G01N27/44791 , G05D7/0694 , H01L21/6715 , Y10T436/2575
Abstract: Apparatuses and methods for manipulating droplets are disclosed. In one embodiment, an apparatus for manipulating droplets is provided, the apparatus including a substrate, multiple arrays of electrodes disposed on the substrate, wherein corresponding electrodes in each array are connected to a common electrical signal, and a dielectric layer disposed on the substrate first side surface and patterned to cover the electrodes.
Abstract translation: 公开了用于操纵液滴的装置和方法。 在一个实施例中,提供了一种用于操纵液滴的装置,该装置包括一个基板,设置在该基板上的多个电极阵列,其中每个阵列中的对应电极连接到公共电信号,以及首先设置在基板上的电介质层 侧表面并图案化以覆盖电极。
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公开(公告)号:US09180450B2
公开(公告)日:2015-11-10
申请号:US14446733
申请日:2014-07-30
Applicant: Duke University
Inventor: Michael G. Pollack , Vamsee K. Pamula , Richard B. Fair
CPC classification number: B01L3/50273 , B01F11/0071 , B01F13/0071 , B01F13/0076 , B01F13/0084 , B01L3/00 , B01L3/5027 , B01L3/502784 , B01L3/502792 , B01L2200/06 , B01L2200/0605 , B01L2200/10 , B01L2300/089 , B01L2300/161 , B01L2300/165 , B01L2400/0415 , B01L2400/0427 , B41J2002/14395 , C25B9/00 , G01N27/44791 , G02B26/005
Abstract: Methods are provided for manipulating droplets. The methods include providing the droplet on a surface comprising an array of electrodes and a substantially co-planer array of reference elements, wherein the droplet is disposed on a first one of the electrodes, and the droplet at least partially overlaps a second one of the electrodes and an intervening one of the reference elements disposed between the first and second electrodes. The methods further include activating the first and second electrodes to spread at least a portion of the droplet across the second electrode and deactivating the first electrode to move the droplet from the first electrode to the second electrode.
Abstract translation: 提供了用于操纵液滴的方法。 所述方法包括在包括电极阵列和基本上共平面的参考元件阵列的表面上提供液滴,其中液滴设置在电极的第一个上,并且液滴至少部分地与第二个 电极和设置在第一和第二电极之间的参考元件中的插入件之一。 所述方法还包括激活第一和第二电极以将液滴的至少一部分扩散穿过第二电极,并且去激活第一电极以使液滴从第一电极移动到第二电极。
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公开(公告)号:US20150060284A1
公开(公告)日:2015-03-05
申请号:US14538322
申请日:2014-11-11
Applicant: DUKE UNIVERSITY
Inventor: Michael G. Pollack , Vamsee K. Pamula , Richard B. Fair
IPC: G01N27/447 , B01L3/00 , B01L7/00 , C12Q1/68
CPC classification number: G01N27/44769 , B01F13/0071 , B01F13/0076 , B01L3/502707 , B01L3/502792 , B01L7/52 , B01L2200/0673 , B01L2200/10 , B01L2200/12 , B01L2300/0645 , B01L2300/0663 , B01L2300/0819 , B01L2300/0864 , B01L2300/0867 , B01L2300/0887 , B01L2300/089 , B01L2300/12 , B01L2300/1827 , B01L2400/0415 , B01L2400/0424 , B81B3/0021 , B81B2201/058 , B81C1/00119 , C12Q1/6846 , G01N27/447 , G01N27/44791 , G05D7/0694 , H01L21/6715 , Y10T436/2575
Abstract: Apparatuses and methods for manipulating droplets are disclosed. In one embodiment, an apparatus for manipulating droplets is provided, the apparatus including a substrate, multiple arrays of electrodes disposed on the substrate, wherein corresponding electrodes in each array are connected to a common electrical signal, and a dielectric layer disposed on the substrate first side surface and patterned to cover the electrodes.
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公开(公告)号:US08871071B2
公开(公告)日:2014-10-28
申请号:US13759416
申请日:2013-02-05
Applicant: Duke University
Inventor: Michael G. Pollack , Vamsee K. Pamula , Richard B Fair
IPC: G01N27/447 , G01N27/453 , C25B9/00 , B01L3/00 , B01F13/00 , B01F11/00 , G02B26/00 , B41J2/14
CPC classification number: B01L3/50273 , B01F11/0071 , B01F13/0071 , B01F13/0076 , B01F13/0084 , B01L3/00 , B01L3/5027 , B01L3/502784 , B01L3/502792 , B01L2200/06 , B01L2200/0605 , B01L2200/10 , B01L2300/089 , B01L2300/161 , B01L2300/165 , B01L2400/0415 , B01L2400/0427 , B41J2002/14395 , C25B9/00 , G01N27/44791 , G02B26/005
Abstract: Methods are provided for manipulating droplets. The methods include providing the droplet on a surface comprising an array of electrodes and a substantially co-planer array of reference elements, wherein the droplet is disposed on a first one of the electrodes, and the droplet at least partially overlaps a second one of the electrodes and an intervening one of the reference elements disposed between the first and second electrodes. The methods further include activating the first and second electrodes to spread at least a portion of the droplet across the second electrode and deactivating the first electrode to move the droplet from the first electrode to the second electrode.
Abstract translation: 提供了用于操纵液滴的方法。 所述方法包括在包括电极阵列和基本上共平面的参考元件阵列的表面上提供液滴,其中液滴设置在电极的第一个上,并且液滴至少部分地与第二个 电极和设置在第一和第二电极之间的参考元件中的插入件之一。 所述方法还包括激活第一和第二电极以将液滴的至少一部分扩散穿过第二电极,并且去激活第一电极以使液滴从第一电极移动到第二电极。
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公开(公告)号:US09110017B2
公开(公告)日:2015-08-18
申请号:US14538322
申请日:2014-11-11
Applicant: Duke University
Inventor: Michael G. Pollack , Vamsee K. Pamula , Richard B. Fair
IPC: B01L3/00 , G01N27/447 , B01F13/00 , B01L7/00 , B81B3/00 , B81C1/00 , C12Q1/68 , G05D7/06 , H01L21/67
CPC classification number: G01N27/44769 , B01F13/0071 , B01F13/0076 , B01L3/502707 , B01L3/502792 , B01L7/52 , B01L2200/0673 , B01L2200/10 , B01L2200/12 , B01L2300/0645 , B01L2300/0663 , B01L2300/0819 , B01L2300/0864 , B01L2300/0867 , B01L2300/0887 , B01L2300/089 , B01L2300/12 , B01L2300/1827 , B01L2400/0415 , B01L2400/0424 , B81B3/0021 , B81B2201/058 , B81C1/00119 , C12Q1/6846 , G01N27/447 , G01N27/44791 , G05D7/0694 , H01L21/6715 , Y10T436/2575
Abstract: Apparatuses and methods for manipulating droplets are disclosed. In one embodiment, an apparatus for manipulating droplets is provided, the apparatus including a substrate, multiple arrays of electrodes disposed on the substrate, wherein corresponding electrodes in each array are connected to a common electrical signal, and a dielectric layer disposed on the substrate first side surface and patterned to cover the electrodes.
Abstract translation: 公开了用于操纵液滴的装置和方法。 在一个实施例中,提供了一种用于操纵液滴的装置,该装置包括一个基板,设置在该基板上的多个电极阵列,其中每个阵列中的对应电极连接到公共电信号,以及首先设置在基板上的电介质层 侧表面并图案化以覆盖电极。
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公开(公告)号:US10022719B2
公开(公告)日:2018-07-17
申请号:US14935823
申请日:2015-11-09
Applicant: Duke University
Inventor: Michael G. Pollack , Vamsee K. Pamula , Richard B. Fair
Abstract: Methods are provided for manipulating droplets. The methods include providing the droplet on a surface comprising an array of electrodes and a substantially co-planer array of reference elements, wherein the droplet is disposed on a first one of the electrodes, and the droplet at least partially overlaps a second one of the electrodes and an intervening one of the reference elements disposed between the first and second electrodes. The methods further include activating the first and second electrodes to spread at least a portion of the droplet across the second electrode and deactivating the first electrode to move the droplet from the first electrode to the second electrode.
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公开(公告)号:US09638662B2
公开(公告)日:2017-05-02
申请号:US14817834
申请日:2015-08-04
Applicant: Duke University
Inventor: Michael G. Pollack , Vamsee K. Pamula , Richard B. Fair
IPC: B01L3/00 , G01N27/447 , B01F13/00 , B01L7/00 , B81B3/00 , B81C1/00 , C12Q1/68 , G05D7/06 , H01L21/67
CPC classification number: G01N27/44769 , B01F13/0071 , B01F13/0076 , B01L3/502707 , B01L3/502792 , B01L7/52 , B01L2200/0673 , B01L2200/10 , B01L2200/12 , B01L2300/0645 , B01L2300/0663 , B01L2300/0819 , B01L2300/0864 , B01L2300/0867 , B01L2300/0887 , B01L2300/089 , B01L2300/12 , B01L2300/1827 , B01L2400/0415 , B01L2400/0424 , B81B3/0021 , B81B2201/058 , B81C1/00119 , C12Q1/6846 , G01N27/447 , G01N27/44791 , G05D7/0694 , H01L21/6715 , Y10T436/2575
Abstract: Apparatuses and methods for manipulating droplets are disclosed. In one embodiment, an apparatus for manipulating droplets is provided, the apparatus including a substrate, multiple arrays of electrodes disposed on the substrate, wherein corresponding electrodes in each array are connected to a common electrical signal, and a dielectric layer disposed on the substrate first side surface and patterned to cover the electrodes.
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公开(公告)号:US20140339082A1
公开(公告)日:2014-11-20
申请号:US14446733
申请日:2014-07-30
Applicant: DUKE UNIVERSITY
Inventor: Michael G. Pollack , Vamsee K. Pamula , Richard B. Fair
IPC: B01L3/00
CPC classification number: B01L3/50273 , B01F11/0071 , B01F13/0071 , B01F13/0076 , B01F13/0084 , B01L3/00 , B01L3/5027 , B01L3/502784 , B01L3/502792 , B01L2200/06 , B01L2200/0605 , B01L2200/10 , B01L2300/089 , B01L2300/161 , B01L2300/165 , B01L2400/0415 , B01L2400/0427 , B41J2002/14395 , C25B9/00 , G01N27/44791 , G02B26/005
Abstract: Methods are provided for manipulating droplets. The methods include providing the droplet on a surface comprising an array of electrodes and a substantially co-planer array of reference elements, wherein the droplet is disposed on a first one of the electrodes, and the droplet at least partially overlaps a second one of the electrodes and an intervening one of the reference elements disposed between the first and second electrodes. The methods further include activating the first and second electrodes to spread at least a portion of the droplet across the second electrode and deactivating the first electrode to move the droplet from the first electrode to the second electrode.
Abstract translation: 提供了用于操纵液滴的方法。 所述方法包括在包括电极阵列和基本上共平面的参考元件阵列的表面上提供液滴,其中液滴设置在电极的第一个上,并且液滴至少部分地与第二个 电极和设置在第一和第二电极之间的参考元件中的插入件之一。 所述方法还包括激活第一和第二电极以将液滴的至少一部分扩散穿过第二电极,并且去激活第一电极以使液滴从第一电极移动到第二电极。
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