公开(公告)号：US06876793B1

公开(公告)日：2005-04-05

申请号：US10731297

申请日：2003-12-09

Applicant: Peiching Ling ,  Wayne Lui ,  Jinliang Chen ,  Jianjun Zhang ,  Ming Xu ,  Yu Chen

Inventor： Peiching Ling ,  Wayne Lui ,  Jinliang Chen ,  Jianjun Zhang ,  Ming Xu ,  Yu Chen

IPC: G02B6/12 ,  G02B6/124 ,  G02B6/34 ,  H04J14/02

CPC classification number: G02B6/12007 ,  G02B6/12002 ,  G02B6/12004 ,  G02B6/124 ,  G02B6/29323 ,  G02B6/29334 ,  G02B2006/121

Abstract: The present invention is a wavelength-selective optical transmission system that includes a first waveguide for transmitting a multiplexed optical signal therethrough. The system further includes a second waveguide coupled to the first waveguide wherein a least one of the first and second waveguides have a set of wavelength-selective Bragg gratings disposed near a coupling section between the first and second waveguides to reflect a reflecting optical signal back to the first waveguide and for transmitting a contra-directional optical signal and a co-directional optical signal having respectively a contra-directional selected wavelength and a co-directional selected wavelength corresponding to the Bragg gratings. One of the contra-directional and co-directional wavelengths is chosen as a designated wavelength, and the reflecting optical signal and one of the contra-directional or co-directional optical signals are outside of a predefined range surrounding the designated wavelength.

Abstract translation: 本发明是一种波长选择性光传输系统，其包括用于传输多路复用光信号的第一波导。 该系统还包括耦合到第一波导的第二波导，其中第一和第二波导中的至少一个波导具有布置在第一和第二波导之间的耦合部分附近的一组波长选择布拉格光栅，以将反射光信号反射回 第一波导和用于发送具有分别对应于布拉格光栅的反向选择波长和共同选择波长的双向光信号和同向光信号。 选择反向和同向波长中的一个作为指定波长，并且反射光信号和反向光信号之一以及指向波长周围的预定范围之外。

公开(公告)号：US20050071142A1

公开(公告)日：2005-03-31

申请号：US10674586

申请日：2003-09-29

Applicant: Yu Chen ,  Yong Xu ,  Jianzhong Chen

Inventor： Yu Chen ,  Yong Xu ,  Jianzhong Chen

IPC: C07B31/00 ,  C07B33/00 ,  G05B17/02 ,  G06F17/13 ,  G06F19/00 ,  G06G7/48 ,  G06G7/58

CPC classification number: G16B5/00

Abstract: A method for simulation of at least one biological and/or chemical reaction pathway comprising: preparing a map of at least one biological and/or chemical reaction pathway; constructing at least one set of binding and reaction equation from the pathway map; constructing at least one set of concentration equation for molecules of the pathway map; constructing an electronic circuit corresponding to every set of equation; determining simulation of pathway by measuring voltage at two or more connection points of the circuit. It is also provided a method for molecular dynamics simulation of biomolecules and/or nano-molecular systems comprising: constructing at least one set of equation representing the molecular dynamics of at least one molecule of the biomolecules and/or the nano-molecular systems; constructing an electronic circuit representing every set of equation; determining molecular dynamics simulation by measuring voltage at two or more connection points of the circuit.

Abstract translation: 一种用于模拟至少一种生物和/或化学反应途径的方法，包括：制备至少一种生物和/或化学反应途径的图谱; 从路径图构建至少一组结合和反应方程; 为路径图的分子构建至少一组浓度方程; 构建对应于每一组方程的电子电路; 通过测量电路的两个或多个连接点处的电压来确定路径的模拟。 还提供了生物分子和/或纳米分子系统的分子动力学模拟的方法，包括：构建代表生物分子和/或纳米分子系统的至少一个分子的分子动力学的至少一组方程; 构建代表每一组方程的电子电路; 通过测量电路两个或多个连接点处的电压来确定分子动力学模拟。

公开(公告)号：US20050067656A1

公开(公告)日：2005-03-31

申请号：US10919657

申请日：2004-08-17

Applicant: Kevin Denis ,  Yu Chen ,  Paul Drzaic ,  Joseph Jacobson ,  Peter Kazlas

Inventor： Kevin Denis ,  Yu Chen ,  Paul Drzaic ,  Joseph Jacobson ,  Peter Kazlas

IPC: H01L21/336 ,  H01L29/786 ,  H01L21/00 ,  H01L21/84 ,  H01L27/01 ,  H01L27/12 ,  H01L31/0392

CPC classification number: H01L29/66765 ,  H01L29/78603

Abstract: Transistors are formed by depositing at least one layer of semiconductor material on a substrate comprising a polyphenylene polyimide. The substrate permits the use of processing temperatures in excess of 300° C. during the processes used to form the transistors, thus allowing the formation of high quality silicon semiconductor layers. The substrate also has a low coefficient of thermal expansion, which closely matches that of silicon, thus reducing any tendency for a silicon layer to crack or delaminate.

Abstract translation: 晶体管通过在包含聚亚苯基聚酰亚胺的衬底上沉积至少一层半导体材料形成。 在用于形成晶体管的工艺期间，衬底允许使用超过300℃的处理温度，从而允许形成高质量的硅半导体层。 该基板也具有低的热膨胀系数，其与硅的热膨胀系数非常接近，从而减少硅层破裂或分层的任何趋势。

公开(公告)号：US06716661B2

公开(公告)日：2004-04-06

申请号：US10147006

申请日：2002-05-16

Applicant: Quanbo Zou ,  Yu Chen ,  Janak Singh ,  Tit Meng Lim ,  Tie Yan ,  Chew Kiat Heng

Inventor： Quanbo Zou ,  Yu Chen ,  Janak Singh ,  Tit Meng Lim ,  Tie Yan ,  Chew Kiat Heng

IPC: H01L2100

CPC classification number: B81C1/00214 ,  B81C2201/0132 ,  F04B43/043

Abstract: Formation of micro-fluidic systems is normally achieved using a multi-wafer fabrication procedure. The present invention teaches how a complete micro-fluidic system can be implemented on a single chip. The invention uses only dry etch processes to form micro-chambers. In particular, it makes use of deep reactive ion etching whereby multiple trenches of differing depths may be formed simultaneously. Buried micro-chambers are formed by isotropically increasing trench widths using an etchant that does not attack the mask so the trenches grow wider beneath the surface until they merge. Deposition of a dielectric layer over the trenches allows some trenches to be sealed and some to be left open. Micro-pumps are formed by including in the micro-chamber roof a layer that is used to change chamber volume either through electrostatically induced motion or through thermal mismatch as a result of its being heated.

Abstract translation: 微流体系统的形成通常使用多晶片制造程序来实现。 本发明教导了如何在单个芯片上实现完整的微流体系统。 本发明仅使用干蚀刻工艺来形成微室。 特别地，它利用深反应离子蚀刻，从而可以同时形成不同深度的多个沟槽。 通过使用不侵蚀掩模的蚀刻剂各向同性地增加沟槽宽度来形成掩埋的微室，使得沟槽在表面下方变得更宽，直到它们合并。 电介质层沉积在沟槽上方允许一些沟槽被密封，有些则被打开。 通过在微室顶中包含用于通过静电诱导运动或通过其被加热的结果的热失配来改变室容积的层而形成微泵。

公开(公告)号：US06521447B2

公开(公告)日：2003-02-18

申请号：US10188641

申请日：2002-07-03

Applicant: Quanbo Zou ,  Uppili Sridhar ,  Yu Chen ,  Tit Meng Lim ,  Emmanuel Selvanayagam Zachariah ,  Tie Yan

Inventor： Quanbo Zou ,  Uppili Sridhar ,  Yu Chen ,  Tit Meng Lim ,  Emmanuel Selvanayagam Zachariah ,  Tie Yan

IPC: C12M134

CPC classification number: B01L3/5027 ,  B01L3/5025 ,  B01L7/52 ,  B01L2200/147 ,  B01L2300/0816 ,  B01L2300/0877 ,  B01L2300/1827 ,  B01L2300/1883 ,  B01L2400/0487 ,  B01L2400/0688

Abstract: The invention describes a thermal cycler which permits simultaneous treatment of multiple individual samples in independent thermal protocols, so as to implement large numbers of DNA experiments simultaneously in a short time. The chamber is thermally isolated from its surroundings, heat flow in and out of the unit being limited to one or two specific heat transfer areas. All heating elements are located within these transfer areas and at least one temperature sensor per heating element is positioned close by. Fluid bearing channels that facilitate sending fluid into, and removing fluid from, the chamber are provided. The chambers may be manufactured as integrated arrays to form units in which each cycler chamber has independent temperature and fluid flow control. Two embodiments of the invention are described together with a process for manufacturing them.

公开(公告)号：US06406861B1

公开(公告)日：2002-06-18

申请号：US09413044

申请日：1999-10-06

Applicant: Daniel R. Henderson ,  Yu Chen ,  De Chao Yu

Inventor： Daniel R. Henderson ,  Yu Chen ,  De Chao Yu

IPC: G01N3353

CPC classification number: A61K48/00 ,  A61M1/3679 ,  Y10S514/885

Abstract: Methods of reducing pre-existing humoral immunity to a viral immunogenic therapeutic agent such as adenovirus, using immunoapheresis are disclosed. Antibodies specific for the viral immunogenic therapeutic agent are selectively removed from the blood of an individual prior to administration of the viral immunogenic therapeutic agent by reaction extracorporeally with an immunosorbent which specifically binds the antibody. After the antibody is selectively removed from the blood, the blood is reinfused into the patient and the viral immunogenic therapeutic agent is administered. The invention also provides kits and compositions for selective removal of anti-viral antibody.

Abstract translation: 公开了使用免疫分离法减少病毒免疫原性治疗剂如腺病毒的预先存在的体液免疫的方法。 在给予病毒免疫原性治疗剂之前，通过与特异性结合抗体的免疫吸附剂体外反应，选择性地从个体的血液中除去病毒免疫原性治疗剂的特异性抗体。 在从血液中选择性地除去抗体后，将血液再次输注到患者体内，并施用病毒免疫原性治疗剂。 本发明还提供用于选择性除去抗病毒抗体的试剂盒和组合物。

公开(公告)号：US6090389A

公开(公告)日：2000-07-18

申请号：US177973

申请日：1998-10-26

Applicant: Yu Chen

Inventor： Yu Chen

IPC: A61K9/00 ,  A61K36/515 ,  A61K36/539 ,  A61K35/78 ,  A61K9/20 ,  A61K9/48

CPC classification number: A61K36/515 ,  A61K9/0034 ,  Y10S514/937 ,  Y10S514/944 ,  Y10S514/945 ,  Y10S514/962 ,  Y10S514/967

Abstract: A method and preparations for the treatment of vaginal yeast and other yeast infections is provided for the treatment of infections caused by Candida albicans and Cryptococcus neoformans. The method and preparations of the invention can also be used for other yeast and fungal infections including systemic, mucosal and cutaneous caused by Candida and Cryptococcus. The vaginal antiyeast and antifungal preparations include, in addition to suppositories and mouth washes, troches, lotions, creams, tablets and capsules containing gentian preparations as an active ingredient obtained from the plant Radix gentianae Longdancao. For systemic fungal infections gentian preparations from the plant Radix gentianae Longdancao are taken orally in the form of lozenges, tablets, capsules or in solution form for gargling or swallowing.

Abstract translation: 提供了用于治疗阴道酵母和其他酵母菌感染的方法和制剂，用于治疗由白色念珠菌和新型隐球蛋白引起的感染。 本发明的方法和制剂也可用于其它酵母和真菌感染，包括由念珠菌和隐球菌引起的全身，粘膜和皮肤。 除了栓剂和漱口剂之外，阴道抗菌和抗真菌制剂还包括从植物龙胆龙胆制得的龙胆制剂作为活性成分的锭剂，洗剂，霜剂，片剂和胶囊剂。 对于系统性真菌感染，来自植物龙胆龙胆的龙胆制剂以锭剂，片剂，胶囊或溶液形式口服口服用于漱口或吞咽。

公开(公告)号：USD1057909S1

公开(公告)日：2025-01-14

申请号：US29951752

申请日：2024-07-11

Applicant: Yu Chen

Designer： Yu Chen

公开(公告)号：USD996411S1

公开(公告)日：2023-08-22

申请号：US29892568

申请日：2023-05-19

Applicant: Yu Chen

Designer： Yu Chen

Abstract: FIG. 1 is a front, right and top perspective view of a case for mobile telephone, showing my design.
FIG. 2 is a rear, left and bottom perspective view thereof.
FIG. 3 is a front elevation view thereof.
FIG. 4 is a rear elevation view thereof.
FIG. 5 is a left side elevation view thereof.
FIG. 6 is a right side elevation view thereof.
FIG. 7 is a top plan view thereof; and,
FIG. 8 is a bottom plan view thereof.

公开(公告)号：USD996410S1

公开(公告)日：2023-08-22

申请号：US29892567

申请日：2023-05-19

Applicant: Yu Chen

Designer： Yu Chen

Abstract: FIG. 1 is a front, right and top perspective view of a case for mobile telephone, showing my design.
FIG. 2 is a rear, left and bottom perspective view thereof.
FIG. 3 is a front elevation view thereof.
FIG. 4 is a rear elevation view thereof.
FIG. 5 is a left side elevation view thereof.
FIG. 6 is a right side elevation view thereof.
FIG. 7 is a top plan view thereof; and,
FIG. 8 is a bottom plan view thereof.
The broken lines depict portions of the case for mobile telephone that form no part of the claimed design.