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公开(公告)号：US20160356700A1
公开(公告)日：2016-12-08
申请号：US15174322
申请日：2016-06-06
Inventor： Justin ROUXEL , Mickael Brun , Alain Gliere , Sergio Nicoletti
IPC: G01N21/17
CPC classification number: G01N21/1702 , G01N29/2418 , G01N29/2425 , G01N2021/1704 , G01N2021/1708 , G01N2201/0245 , G01N2291/021 , G01N2291/02872
Abstract: Modular photoacoustic detection device comprising: a photoacoustic cell including at least two chambers connected by at least two capillaries and forming a Helmholtz type differential acoustic resonator; acoustic detectors coupled to the chambers; a light source capable of emitting a light beam having at least one wavelength capable of exciting a gas intended to be detected and which can be modulated to a resonance frequency of the photoacoustic cell; a first photonic circuit optically coupling the light source to an input face of a first of the chambers; wherein the first photonic circuit is arranged in a detachable manner in a first housing formed in the acoustic cell and emerging on the input face of the first chamber.
Abstract translation: 其中所述第一光子电路以可分离的方式布置在形成在所述声学单元中的第一壳体中并且出现在所述第一室的输入面上。
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公开(公告)号：US20160169808A1
公开(公告)日：2016-06-16
申请号：US14566708
申请日：2014-12-10
Applicant: Molecular Devices, LLC
Inventor： Josef J. Atzler , Michael Katzlinger , Georg Kronberger , Bernhard Schinwald
IPC: G01N21/76
CPC classification number: G01N21/76 , G01J3/02 , G01N21/15 , G01N21/253 , G01N21/763 , G01N27/223 , G01N35/028 , G01N2021/015 , G01N2021/155 , G01N2035/1025 , G01N2201/0225 , G01N2201/0245 , G01N2201/0446 , G01N2201/0806
Abstract: In a sample analyzing apparatus, an injector assembly injects a reagent onto a sample, and luminescent light from the sample is transmitted to a detector. The assembly may be movable toward and away from the sample. The assembly may include one or more needles that communicate with one or more reservoirs supplying reagent or other liquids. The assembly may include a light guide for communicating with the detector. A cartridge may be provided in which the assembly, one or more reservoirs, and one or more pumps are disposed. The cartridge and/or the apparatus may be configured for enabling rinsing or priming to be done outside the apparatus. The cartridge and/or the apparatus may include one or more types of sensors configured for detecting, for example, the presence of liquid or bubbles in one or more locations of the apparatus and/or the cartridge.
Abstract translation: 在样品分析装置中，注射器组件将试剂注射到样品上，并将来自样品的发光发射到检测器。 组件可以朝向和远离样品移动。 组件可以包括与供应试剂或其它液体的一个或多个储存器连通的一个或多个针。 组件可以包括用于与检测器通信的光导。 可以提供盒，其中设置组件，一个或多个储存器和一个或多个泵。 墨盒和/或设备可以被配置为使得能够在设备外进行冲洗或启动。 药筒和/或装置可以包括一种或多种类型的传感器，其被配置用于例如在装置和/或药筒的一个或多个位置中检测液体或气泡的存在。
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73.发明授权Mobile water analysis arrangement and method for determining an analyte in a water sample 有权用于测定水样中分析物的流动水分析装置和方法公开(公告)号：US09012234B2
公开(公告)日：2015-04-21
申请号：US13122560
申请日：2009-09-28
Applicant: Ulrich Lundgreen , Aria Farjam , Rolf Uthemann , Andreas Mitreiter , Isabel Huenig , Markus Lenhard , Rainer Froemel , Hans-Joachim Kumpch
Inventor： Ulrich Lundgreen , Aria Farjam , Rolf Uthemann , Andreas Mitreiter , Isabel Huenig , Markus Lenhard , Rainer Froemel , Hans-Joachim Kumpch
CPC classification number: G01N33/1893 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L2300/0645 , B01L2300/0654 , B01L2300/0681 , B01L2300/0838 , B01L2400/0475 , G01N21/3151 , G01N21/78 , G01N27/4167 , G01N27/4168 , G01N33/1886 , G01N2201/0245
Abstract: A mobile water analyzing system for determining an analyte in a water sample includes a basic unit and a test element configured to be inserted into the basic unit. The test element includes a sample line with an inlet opening configured to receive the water sample, a measuring section forming a measuring track and configured to allow the determination of an analyte, a pump opening, and a key reagent disposed inside the sample line. The basic unit includes a test element receptacle configured to hold the inserted test element, an analyzer with an analyzer measuring track formed by the measuring section, and a pump actuator cooperatively connected with the pump opening.
Abstract translation: 用于确定水样品中的分析物的移动水分析系统包括基本单元和被配置为插入到基本单元中的测试元件。 测试元件包括具有被配置为接收水样本的入口开口的样品管线，形成测量轨道的测量部分，并且被配置为允许确定分析物，泵开口和设置在样品管线内部的密钥试剂。 基本单元包括被配置为保持插入的测试元件的测试元件插座，具有由测量部分形成的分析器测量轨迹的分析器和与泵开口协作连接的泵致动器。
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公开(公告)号：US08654323B2
公开(公告)日：2014-02-18
申请号：US13241960
申请日：2011-09-23
Applicant: Daisuke Matsumoto , Yasunori Shiraki
Inventor： Daisuke Matsumoto , Yasunori Shiraki
IPC: G01J1/00
CPC classification number: G01N27/44721 , B01L3/502715 , B01L9/527 , B01L2300/0654 , G01N21/0303 , G01N21/05 , G01N2021/0346 , G01N2201/0245
Abstract: An analyzing apparatus includes a microchip, a detecting unit and an analyzing-measuring unit. The microchip is formed of a light transmissive material formed with a separation fluid channel that is a light measuring part. The detecting unit includes an emitted-light guiding unit that emits light to the separation fluid channel, and a received-light guiding unit that receives light through the separation fluid channel. The emitted-light guiding unit or the received-light guiding unit placed at a position facing a microchip support table via the microchip abuts the microchip, and pushes the microchip in a direction toward the microchip support table. The analyzing-measuring unit includes the detecting unit, the emitted-light guiding unit and the received-light guiding unit, and detects a constituent of a sample filled in the separation fluid channel.
Abstract translation: 分析装置包括微芯片，检测单元和分析测量单元。 微芯片由形成有作为光测量部分的分离流体通道形成的透光材料形成。 检测单元包括向分离流体通道发射光的发射光引导单元和通过分离流体通道接收光的接收光引导单元。 经由微芯片放置在面向微芯片支撑台的位置处的发射光引导单元或接收光引导单元抵靠微芯片，并且朝向微芯片支撑台的方向推动微芯片。 分析测量单元包括检测单元，发射光引导单元和接收光引导单元，并且检测填充在分离流体通道中的样品的成分。
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公开(公告)号：US08557569B2
公开(公告)日：2013-10-15
申请号：US12217410
申请日：2008-07-03
Applicant: Steven J. Boege , Howard G. King , Eugene F. Young , Johannes P. Sluis , Mark F. Oldham
Inventor： Steven J. Boege , Howard G. King , Eugene F. Young , Johannes P. Sluis , Mark F. Oldham
CPC classification number: G01N21/6486 , B01L7/52 , C12Q2545/101 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/0628 , G01N2201/0635 , Y10S435/808 , Y10S435/809
Abstract: An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with excitation beams generated by a light source. The light source can include an area light array of light emitting diodes, one or more solid state lasers, one or more micro-wire lasers, or a combination thereof. According to various embodiments, a Fresnel lens can be disposed along a beam bath between the light source and the reaction regions. Methods of analysis using the optical instrument are also provided.
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Patent Agency Ranking
76.发明申请公开(公告)号：US20110212538A1
公开(公告)日：2011-09-01
申请号：US13122561
申请日：2009-09-28
Applicant: Ulrich Lundgreen , Aria Farjam , Rolf Uthemann , Andreas Mitreiter , Isabel Huenig , Markus Lenhard , Rainer Froemel , Hans-Joachim Kumpch
Inventor： Ulrich Lundgreen , Aria Farjam , Rolf Uthemann , Andreas Mitreiter , Isabel Huenig , Markus Lenhard , Rainer Froemel , Hans-Joachim Kumpch
CPC classification number: G01N33/1893 , B01L3/5027 , B01L3/502715 , B01L3/50273 , B01L2300/0645 , B01L2300/0654 , B01L2300/0681 , B01L2300/0838 , B01L2400/0475 , G01N21/3151 , G01N21/78 , G01N27/4167 , G01N27/4168 , G01N33/1886 , G01N2201/0245
Abstract: A method for determining an analyte in a water sample with a mobile water analyzing system having a basic unit and a test element insertable in the basic unit, the method comprising providing the test element and the basic unit. The test element is inserted into a test element receptacle of the basic unit. The water sample is transported forward from an inlet opening to a measuring section of the test element. A first analyzing of the water sample is performed in the measuring section with an analyzer of the basic unit. The water sample is transported forward from the measuring section to the first reagent section of the test element. The water sample is transported backward from the first reagent section to the measuring section of the test element. A second analyzing of the water sample is performed in the measuring section with the analyzer of the basic unit.
Abstract translation: 一种利用移动式水分析系统确定水样中分析物的方法，所述移动式水分析系统具有可插入基本单元的基本单元和测试元件，该方法包括提供测试元件和基本单元。 将测试元件插入到基本单元的测试元件容器中。 水样从入口开口向前传送到测试元件的测量部分。 在测量部分用基本单元的分析仪进行水样的第一次分析。 水样从测量部分向前传送到测试元件的第一试剂部分。 水样从第一试剂部向测试部的测定部向后方传送。 用基本单位分析仪在测量部分进行水样的第二次分析。
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公开(公告)号：US20100260903A1
公开(公告)日：2010-10-14
申请号：US12521803
申请日：2008-01-04
Applicant: Ai-Ping . Wei , Raj Rajagopal , Catherine Bineau
Inventor： Ai-Ping . Wei , Raj Rajagopal , Catherine Bineau
CPC classification number: G01N33/03 , G01N21/6428 , G01N21/645 , G01N2201/0221 , G01N2201/0245
Abstract: A method of determining the quality of oil by irradiating the oil at a first wavelength, e.g., of about 470 nm, measuring a level of fluorescence of the oil at a second wavelength, e.g., of about 520 nm, comparing the measured fluorescence level to a predetermined threshold level to determine whether or not the oil quality is acceptable. The oil is preferably discarded if the measured fluorescence level exceeds the predetermined threshold level, which can be generally dependent on the oil composition. The fluorescence is correlated to the level of polar components in the oil. Also described are devices for determining the quality of oil via fluorescence.
Abstract translation: 通过以例如约470nm的第一波长（例如约470nm）照射油来测定油的质量的方法，测量在第二波长例如约520nm的油的荧光水平，将测量的荧光水平与 预定的阈值水平以确定油品质量是否可接受。 如果测量的荧光水平超过预定阈值水平，则油优选地被丢弃，其通常可以取决于油组成。 荧光与油中极性组分的水平相关。 还描述了用于通过荧光确定油质量的装置。
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公开(公告)号：US20070154939A1
公开(公告)日：2007-07-05
申请号：US11711416
申请日：2007-02-26
Applicant: Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , John Atwood , Susan Stone , Judith Atwood
Inventor： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , John Atwood , Susan Stone , Judith Atwood
CPC classification number: G01N21/6428 , B01L3/5085 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0663 , B01L2300/1811 , C12Q1/686 , C12Q2545/101 , G01N21/274 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/06113 , G01N2201/0628 , G01N2201/0635 , G01N2201/0636 , G01N2201/068 , C12Q2563/107
Abstract: An optical instrument monitors PCR replication of DNA in a reaction apparatus having a temperature cycled block with vials of reaction ingredients including dye that fluoresces in presence of double-stranded DNA. A beam splitter passes an excitation beam to the vials to fluoresce the dye. An emission beam from the dye is passed by the beam splitter to a CCD detector from which a processor computes DNA concentration. A reference strip with a plurality of reference emitters emit reference beams of different intensity, from which the processor selects an optimum emitter for compensating for drift. Exposure time is automatically adjusted for keeping within optimum dynamic ranges of the CCD and processor. A module of the beam splitter and associated optical filters is associated with selected dye, and is replaceable for different dyes.
Abstract translation: 光学仪器监测具有温度循环阻滞的反应装置中DNA的PCR复制，所述反应装置具有小瓶的反应成分，包括在双链DNA存在下发荧光的染料。 分束器将激发光束传递到小瓶以使染料发荧光。 来自染料的发射光束通过分束器传递到CCD检测器，处理器从该CCD检测器计算DNA浓度。 具有多个参考发射器的参考条发射不同强度的参考光束，处理器从该参考光束选择用于补偿漂移的最佳发射器。 自动调整曝光时间以保持CCD和处理器的最佳动态范围。 分束器和相关的滤光器的模块与选定的染料相关联，并且可替代不同的染料。
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公开(公告)号：US20070148761A1
公开(公告)日：2007-06-28
申请号：US11705856
申请日：2007-02-13
Applicant: Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Judith Atwood , John Atwood , Susan Stone
Inventor： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Judith Atwood , John Atwood , Susan Stone
IPC: C12M1/34
CPC classification number: G01N21/6428 , B01L3/5085 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0663 , B01L2300/1811 , C12Q1/686 , C12Q2545/101 , G01N21/274 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/06113 , G01N2201/0628 , G01N2201/0635 , G01N2201/0636 , G01N2201/068 , C12Q2563/107
Abstract: An optical instrument monitors PCR replication of DNA in a reaction apparatus having vials of reaction ingredients. A beam splitter passes an excitation beam to the vials. An emission beam from the reaction ingredients can be passed by the beam splitter to a detector from which a processor can compute DNA concentration. A reference strip with a plurality of reference emitters can be provided which emits reference beams of different intensity, from which the processor can select an optimum emitter for compensating for drift. Exposure time can be automatically adjusted for keeping within optimum dynamic ranges of the detector and processor. A module of the beam splitter and associated optical filters can be associated with a selected dye, and can be replaceable for different dyes.
Abstract translation: 光学仪器在具有小瓶反应成分的反应设备中监测DNA的PCR复制。 分束器将激发光束传递到小瓶。 来自反应成分的发射光束可以通过分光器传递到检测器，处理器可以从该分光器计算DNA浓度。 可以提供具有多个参考发射器的参考条，其发射不同强度的参考光束，处理器可以从其中选择用于补偿漂移的最佳发射器。 曝光时间可以自动调整，以保持在检测器和处理器的最佳动态范围内。 分束器和相关联的滤光器的模块可以与所选择的染料相关联，并且可以替代不同的染料。
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公开(公告)号：US20060128009A1
公开(公告)日：2006-06-15
申请号：US11333483
申请日：2006-01-17
Applicant: Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Susan Stone , Judith Atwood
Inventor： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Susan Stone , Judith Atwood
IPC: C12M1/34
CPC classification number: G01N21/6428 , B01L3/5085 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0663 , B01L2300/1811 , C12Q1/686 , C12Q2545/101 , G01N21/274 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/06113 , G01N2201/0628 , G01N2201/0635 , G01N2201/0636 , G01N2201/068 , C12Q2563/107
Abstract: An optical instrument monitors PCR replication of DNA in a reaction apparatus having a temperature cycled block with vials of reaction ingredients including dye that fluoresces in presence of double-stranded DNA. A beam splitter passes an excitation beam to the vials to fluoresce the dye. An emission beam from the dye is passed by the beam splitter to a CCD detector from which a processor computes DNA concentration. A reference strip with a plurality of reference emitters emit reference beams of different intensity, from which the processor selects an optimum emitter for compensating for drift. Exposure time is automatically adjusted for keeping within optimum dynamic ranges of the CCD and processor. A module of the beam splitter and associated optical filters is associated with selected dye, and is replaceable for different dyes.
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