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    Optimizing fracture toughness of polymeric stent
    81.
    发明申请
    Optimizing fracture toughness of polymeric stent 有权
    优化聚合物支架的断裂韧性

    公开(公告)号：US20080147164A1

    公开(公告)日：2008-06-19

    申请号：US11639079

    申请日：2006-12-13

    Applicant: David C. Gale ,  Bin Huang ,  Vincent J. Guertguian ,  Syed F.A. Hossainy

    Inventor： David C. Gale ,  Bin Huang ,  Vincent J. Guertguian ,  Syed F.A. Hossainy

    IPC: A61F2/06

    CPC classification number: A61F2/95 ,  A61F2/91 ,  A61F2002/9522 ,  A61L31/06 ,  Y10T29/49771 ,  Y10T29/49908 ,  Y10T29/49913 ,  Y10T29/49938 ,  C08L67/04

    Abstract: Disclosed herein is a method of fabricating a stent assembly comprising radially expanding a polymeric tube to an optimal degree of radial expansion; fabricating a stent from the expanded polymeric tube; and crimping the stent onto a catheter assembly, wherein the temperature of the stent during crimping is an optimal crimping temperature, wherein the optimal degree of radial expansion and the optimal crimping temperature correspond to an optimal fracture toughness exhibited by the crimped stent upon its deployment as a function of degree of radial expansion and crimping temperature.

    Abstract translation: 本文公开了一种制造支架组件的方法，包括将聚合物管径向膨胀至最佳径向膨胀程度; 从扩张的聚合物管制造支架; 并将支架卷曲到导管组件上，其中在卷曲期间支架的温度是最佳卷曲温度，其中最佳径向膨胀程度和最佳卷曲温度对应于卷曲支架在展开时表现出的最佳断裂韧性 径向膨胀度和卷曲温度的函数。

    Method of crimping a polymeric stent
    85.
    发明申请
    Method of crimping a polymeric stent 有权
    卷曲聚合物支架的方法

    公开(公告)号：US20070271763A1

    公开(公告)日：2007-11-29

    申请号：US11441996

    申请日：2006-05-25

    Applicant: Bin Huang ,  Patrick Wu

    Inventor： Bin Huang ,  Patrick Wu

    IPC: B21D39/00

    CPC classification number: A61F2/90 ,  A61F2002/068 ,  A61F2230/0054 ,  Y10T29/49865 ,  Y10T29/49913 ,  Y10T29/49995

    Abstract: A method of crimping a stent to a support element is disclosed, the method comprising: positioning a polymeric stent around a support element; heating the stent, wherein the heated stent is above ambient temperature; and allowing the heated stent to radially contract onto the support element, wherein the heated stent radially contracts at least partially due to heating the stent.

    Abstract translation: 公开了将支架卷曲到支撑元件的方法，所述方法包括：将聚合物支架定位在支撑元件周围; 加热支架，其中加热的支架高于环境温度; 并且允许加热的支架径向收缩到支撑元件上，其中由于加热支架，加热支架至少部分地径向收缩。

    Method of fabricating an implantable medical device to reduce chance of late inflammatory response
    86.
    发明申请
    Method of fabricating an implantable medical device to reduce chance of late inflammatory response 有权
    制造可植入医疗器械以减少炎症反应迟发的方法

    公开(公告)号：US20070253999A1

    公开(公告)日：2007-11-01

    申请号：US11444596

    申请日：2006-05-31

    Applicant: Bin Huang ,  David Gale

    Inventor： Bin Huang ,  David Gale

    IPC: A61F2/06

    CPC classification number: A61L31/06 ,  A61F2/915 ,  A61L31/148 ,  B23K26/402 ,  B23K2103/42 ,  B23K2103/50 ,  B29B13/02 ,  B29C71/0063 ,  B29L2031/7532 ,  C08L67/04

    Abstract: The invention provides a method for fabricating an implantable medical device to increase biocompatibility of the device, the method comprising: heat setting a polymer construct, wherein the polymer construct is at a temperature range of from about Tg to about 0.6(Tm−Tg)+Tg such that the set polymer construct comprises a crystalline structure having crystals at a size less than about 2 microns; and fabricating an implantable medical device from the heat set polymer construct.

    Abstract translation: 本发明提供一种用于制造可植入医疗装置以提高装置的生物相容性的方法，所述方法包括：热定形聚合物构造物，其中所述聚合物构造物的温度范围为约Tg至约0.6（Tm-Tg）+ Tg使得所述聚合物构件包含具有小于约2微米尺寸的晶体的晶体结构; 以及从所述热固性聚合物构造物制造可植入医疗装置。

    Method of fabricating an implantable medical device using gel extrusion and charge induced orientation
    87.
    发明申请
    Method of fabricating an implantable medical device using gel extrusion and charge induced orientation 审中-公开
    使用凝胶挤出和电荷诱导取向制造可植入医疗器械的方法

    公开(公告)号：US20070179219A1

    公开(公告)日：2007-08-02

    申请号：US11345073

    申请日：2006-01-31

    Applicant: Bin Huang ,  David Gale

    Inventor： Bin Huang ,  David Gale

    IPC: C08L1/10

    CPC classification number: A61F2/82 ,  A61F2210/0004 ,  A61F2240/001 ,  A61F2250/0067 ,  A61L31/042 ,  A61L31/06 ,  A61L31/148 ,  B23K2103/42 ,  B23K2103/50 ,  C08L5/08 ,  C08L67/04

    Abstract: The invention provides a method of manufacturing an implantable medical device, the method comprising: (a) disposing a polymer fluid comprising a solvent and a matrix polymer into a forming apparatus for forming a polymeric part; (b) cooling the formed polymeric part upon removal from the apparatus, the cooled polymeric part comprises the polymer and a substantial portion of the solvent from the polymer fluid; and (c) fabricating an implantable medical device from the cooled polymeric part.

    Abstract translation: 本发明提供了一种制造可植入医疗装置的方法，该方法包括：（a）将包含溶剂和基质聚合物的聚合物流体置于用于形成聚合物部分的成形装置中; （b）在从装置上取出后冷却形成的聚合物部分，冷却的聚合物部分包含聚合物和大部分来自聚合物流体的溶剂; 和（c）从冷却的聚合物部件制造可植入医疗装置。

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