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公开(公告)号：US10166131B2
公开(公告)日：2019-01-01
申请号：US15058407
申请日：2016-03-02
Inventor： Michael Schwager , Martin Frei , Suk-Woo Ha
Abstract: Stent delivery system having a contracted delivery configuration and an expanded deployed configuration is provided. The stent delivery system includes a stent having a plurality of expandable elements and a plurality of interstices disposed between adjacent expandable elements, and a delivery catheter having an inflatable balloon including creases extending non-uniformly within the interstices of the stent in the contracted delivery configuration. Each crease defines a maximum radial height within a corresponding interstice, and the maximum radial heights of the creases vary. A method for stenting at a target site within a patient's vessel including providing a stent delivery system is also provided.
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公开(公告)号：US09398947B2
公开(公告)日：2016-07-26
申请号：US13942215
申请日：2013-07-15
Inventor： Milisav Obradovic , Rainer Bregulla
CPC classification number: A61F2/07 , A61F2/852 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/072 , A61F2002/91575 , A61F2220/0058 , A61F2250/0063
Abstract: A stent-graft including an inner stent having a wall structure including juxtaposed strut-patterns with interconnected struts and connectors connecting the strut-patterns is described. The wall structure of the inner stent has a predetermined length. An outer stent is coaxially arranged around the inner stent and has a wall structure including juxtaposed strut-patterns with interconnected struts and connectors connecting the strut-patterns. The wall structure of the outer stent has a predetermined length and a flexible stretchable material layer arranged between the inner stent and the outer stent. The wall structure of the inner stent has a design differing from the design of the wall structure of the outer stent and the length of the inner stent is equal to the length of the outer stent.
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公开(公告)号：US20160175130A1
公开(公告)日：2016-06-23
申请号：US15058407
申请日：2016-03-02
Inventor： Michael Schwager , Martin Frei , Suk-Woo Ha
CPC classification number: A61F2/958 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91558 , A61F2002/9522 , A61F2002/9583 , A61F2310/00011 , A61M2025/1004 , Y10T29/49927
Abstract: Stent delivery system having a contracted delivery configuration and an expanded deployed configuration is provided. The stent delivery system includes a stent having a plurality of expandable elements and a plurality of interstices disposed between adjacent expandable elements, and a delivery catheter having an inflatable balloon including creases extending non-uniformly within the interstices of the stent in the contracted delivery configuration. Each crease defines a maximum radial height within a corresponding interstice, and the maximum radial heights of the creases vary. A method for stenting at a target site within a patient's vessel including providing a stent delivery system is also provided.
Abstract translation: 提供具有合同传送配置和扩展部署配置的支架传送系统。 支架输送系统包括具有多个可扩张元件的支架和设置在相邻的可膨胀元件之间的多个间隙，以及具有可膨胀气囊的输送导管，其包括在收缩递送构型中在支架的空隙内不均匀延伸的折痕。 每个折痕限定相应空隙内的最大径向高度，并且折痕的最大径向高度变化。 还提供了一种用于在患者容器内的靶部位进行支架置入的方法，包括提供支架输送系统。
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4.发明授权Method, apparatus, and electrolytic solution for electropolishing metallic stents 有权用于电抛光金属支架的方法，设备和电解液公开(公告)号：US09255341B2
公开(公告)日：2016-02-09
申请号：US14135279
申请日：2013-12-19
Inventor： Elena Wulf
CPC classification number: C25F3/16 , A61L31/14 , A61L2400/18 , C25F7/00
Abstract: An apparatus, a method, and an electrolytic solution are described for electropolishing metallic stents made, for example, of high-strength medical alloys. The apparatus may include an electropolishing container made from material of low thermal conductivity. The apparatus may include at least one spiral cathode for optimization of solution agitation and/or voltage distribution in the electrolytic solution. Further, an electrolytic solution including at least dimethylsulfate is described. A method for improved electropolishing to consistently produce smooth surfaces is also described.
Abstract translation: 描述了用于电抛光例如由高强度医用合金制成的金属支架的装置，方法和电解液。 该装置可以包括由导热性低的材料制成的电解抛光容器。 该装置可以包括用于优化电解溶液中的溶液搅拌和/或电压分布的至少一个螺旋阴极。 此外，描述至少包含硫酸二甲酯的电解液。 还描述了用于改进电解抛光以一致地产生光滑表面的方法。
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公开(公告)号：US20150196407A1
公开(公告)日：2015-07-16
申请号：US14665764
申请日：2015-03-23
IPC: A61F2/966
CPC classification number: A61F2/966 , A61M25/005
Abstract: The invention relates to a catheter for delivery of a self-expanding stent into a body lumen, comprising a shaft having a distal end and a proximal end, the shaft defining a lumen and a stent accommodating portion at its outside for carrying a self-expanding stent, a catheter tip arranged at the distal end of the shaft, a sheath arranged concentrically to the shaft, a pusher coil arranged concentrically in between the shaft and the sheath, and proximal to the stent accommodating portion, wherein the sheath comprises an inside layer, an outside layer, and a wire layer of interwoven wires, the wire layer being arranged in between the inside layer and the outside layer.
Abstract translation: 本发明涉及一种用于将自扩张支架输送到体腔中的导管，包括具有远端和近端的轴，所述轴在其外部限定内腔和支架容纳部分，用于承载自扩张 支架，布置在轴的远端的导管尖端，与轴同心地布置的护套，同心地布置在轴和护套之间并且靠近支架容纳部分的推动器线圈，其中护套包括内层 ，外层和交织丝的线层，所述线层布置在所述内层和外层之间。
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Patent Agency Ranking
6.发明申请METHODS AND APPARATUS FOR STENTING COMPRISING ENHANCED EMBOLIC PROTECTION COUPLED WITH IMPROVED PROTECTIONS AGAINST RESTENOSIS AND THROMBUS FORMATION 有权用于包括增强的保护性保护的改进方法和装置与改进的保护和血栓形成的保护公开(公告)号：US20140324157A1
公开(公告)日：2014-10-30
申请号：US14323658
申请日：2014-07-03
Inventor： Joost J. Fierens , Silvio R. Schaffner , Marc Gianotti , Gerd Seibold , Randolf von Oepen
CPC classification number: A61F2/07 , A61F2/82 , A61F2/856 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/0086 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2220/0008 , A61F2220/0016 , A61F2220/005
Abstract: Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
Abstract translation: 提供了用于支架置入的装置和方法，其包括附着于多孔生物相容性材料的支架，所述多孔生物相容性材料可渗透内皮细胞向内生长，但不能透过预定尺寸的栓塞。 提供优选的支架设计，以及优选的制造技术。 还提供了用于血管分支的装置和方法。 此外，本发明的实施方案可以包括被配置用于局部递送治疗剂的涂层。 预期本发明的实施方案可提供增强的栓塞保护，改善的力分布和改善的再交联性，同时降低再狭窄和血栓形成的风险。
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7.发明申请METHOD, APPARATUS, AND ELECTROLYTIC SOLUTION FOR ELECTROPOLISHING METALLIC STENTS 有权用于电镀金属棒的方法，装置和电解质公开(公告)号：US20140110272A1
公开(公告)日：2014-04-24
申请号：US14135279
申请日：2013-12-19
Inventor： Elena Wulf
IPC: C25F3/16
CPC classification number: C25F3/16 , A61L31/14 , A61L2400/18 , C25F7/00
Abstract: An apparatus, a method, and an electrolytic solution are described for electropolishing metallic stents made, for example, of high-strength medical alloys. The apparatus may include an electropolishing container made from material of low thermal conductivity. The apparatus may include at least one spiral cathode for optimization of solution agitation and/or voltage distribution in the electrolytic solution. Further, an electrolytic solution including at least dimethylsulfate is described. A method for improved electropolishing to consistently produce smooth surfaces is also described.
Abstract translation: 描述了用于电抛光例如由高强度医用合金制成的金属支架的装置，方法和电解液。 该装置可以包括由导热性低的材料制成的电解抛光容器。 该装置可以包括用于优化电解溶液中的溶液搅拌和/或电压分布的至少一个螺旋阴极。 此外，描述至少包含硫酸二甲酯的电解液。 还描述了用于改进电解抛光以一致地产生光滑表面的方法。
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8.发明申请Methods and apparatus for stenting comprising enhanced embolic protection coupled with improved protections against restenosis and thrombus formation 有权用于支架置入的方法和装置包括增强的栓塞保护以及改进的针对再狭窄和血栓形成的保护公开(公告)号：US20040236407A1
公开(公告)日：2004-11-25
申请号：US10859636
申请日：2004-06-03
Inventor： Joost J. Fierens , Silvio R. Schaffner , Marc Gianotti , Gerd Seibold , Randolf von Oepen
IPC: A61F002/06
CPC classification number: A61F2/07 , A61F2/82 , A61F2/856 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/0086 , A61F2002/91508 , A61F2002/91533 , A61F2002/91558 , A61F2220/0008 , A61F2220/0016 , A61F2220/005
Abstract: Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
Abstract translation: 提供了用于支架置入的装置和方法，其包括附着于多孔生物相容性材料的支架，所述多孔生物相容性材料可渗透内皮细胞向内生长，但不能透过预定尺寸的栓塞。 提供优选的支架设计，以及优选的制造技术。 还提供了用于血管分支的装置和方法。 此外，本发明的实施方案可以包括被配置用于局部递送治疗剂的涂层。 预期本发明的实施方案可提供增强的栓塞保护，改善的力分布和改善的再交联性，同时降低再狭窄和血栓形成的风险。
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公开(公告)号：US09375304B2
公开(公告)日：2016-06-28
申请号：US14677331
申请日：2015-04-02
Inventor： Boris Anukhin , David Mackiewicz , Michael L. Green , Sanjay Shrivastava
CPC classification number: A61F2/01 , A61F2/88 , A61F2002/011 , A61F2002/016 , A61F2210/0057 , A61F2220/0016 , A61F2230/0006 , A61F2230/005 , A61F2230/0069 , A61F2230/0091 , A61F2240/001 , A61F2250/0029 , A61F2250/0039 , A61F2250/0059 , Y10T29/49826
Abstract: An implantable lumen filter is described. The filter may include a body formed from an elongate member. The body may include loops encircling an axis extending along the length of the body. The body may be sized to be implanted into a body lumen. The body may be capable of transitioning from a collapsed state to a deployed state. The filter may include a first group of a plurality of members positioned around at least one loop of said body. At least a portion of the plurality of members may be oriented towards the axis. The plurality of members may be arranged to capture and/or lyse particulates of a selected size and/or to inhibit the particulates from passing through the body. Methods to of making, deploying, and retrieving the same are described.
Abstract translation: 描述可植入管腔滤器。 过滤器可以包括由细长构件形成的主体。 身体可以包括环绕沿着身体长度延伸的轴线的环。 身体的尺寸可以被植入体腔内。 身体可能能够从折叠状态转换到展开状态。 过滤器可以包括围绕所述主体的至少一个环定位的多个构件的第一组。 多个构件的至少一部分可以朝向轴线定向。 多个构件可以布置成捕获和/或溶解选定尺寸的颗粒和/或抑制颗粒通过身体。 描述了制作，部署和检索该方法的方法。
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10.发明申请COLD-MOLDING PROCESS FOR LOADING A STENT ONTO A STENT DELIVERY SYSTEM 审中-公开用于将STENT加载到STENT交付系统的冷模工艺公开(公告)号：US20130239396A1
公开(公告)日：2013-09-19
申请号：US13779683
申请日：2013-02-27
Inventor： Michael Schwager , Martin Frei , Suk-Woo Ha
IPC: A61F2/958
CPC classification number: A61F2/958 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91558 , A61F2002/9522 , A61F2002/9583 , A61F2310/00011 , A61M2025/1004 , Y10T29/49927
Abstract: A method of making a stent delivery system is provided in which a delivery catheter has a balloon that extends non-uniformly into interstices of a stent. In accordance with the method a balloon/stent/crimping tube assembly is placed in a crimping tool, the balloon is inflated, and the crimping tool is actuated to compress the stent on the outside of the balloon without application of heat or chemicals, thereby causing creases of the balloon to extend non-uniformly into the interstices of the stent. Optionally, pillows may be formed in the balloon to prevent longitudinal movement of the stent with respect to the balloon during intravascular delivery. One or more secondary crimpings also may be performed to achieve a smoother delivery profile.
Abstract translation: 提供一种制造支架输送系统的方法，其中输送导管具有不均匀地延伸到支架的间隙中的气囊。 根据该方法，气球/支架/压接管组件放置在压接工具中，气囊膨胀，并且压接工具被致动以在气囊的外侧压缩支架而不施加热或化学物质，从而导致 球囊的折痕不均匀地延伸到支架的间隙中。 任选地，可以在气囊中形成枕头以防止在血管内递送期间支架相对于气囊的纵向运动。 也可以执行一个或多个二次卷曲以实现更平滑的传送轮廓。
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