公开(公告)号：US12287282B2

公开(公告)日：2025-04-29

申请号：US17758291

申请日：2020-12-28

Applicant: ARYBALLE

Inventor： Cyril Herrier ,  David Harbine ,  Yanis Caritu

IPC: G01N21/27 ,  G01N21/552 ,  G01N21/78

Abstract: A method for recalibrating an electronic nose includes successively injecting, into a measurement chamber, reference gases that do not contain target compounds and that have various values of relative humidity. A measurement signal is determined in the course of each injection. Then, for each reference gas, a baseline is determined, which baseline is representative of the determined measurement signal. The baseline is also associated with the relative humidity of the reference gas present. A second correction function is determined on the basis of the determined baselines and of the predetermined values of relative humidity. The second correction function is then stored in a processing unit instead of a first correction function.

公开(公告)号：US20240280495A1

公开(公告)日：2024-08-22

申请号：US18568555

申请日：2022-06-06

Applicant: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES ,  ARYBALLE

Inventor： Loic LAPLATINE ,  Cyril HERRIER ,  Thierry LIVACHE

IPC: G01N21/77 ,  G01N21/25

CPC classification number: G01N21/7703 ,  G01N21/253 ,  G01N2021/7779

Abstract: An interferometric system for detecting analytes present in a fluid sample, including: an array of Mach-Zehnder interferometers arranged periodically and rectangularly whose arms extend in a spiral and/or serpentine fashion with an aspect ratio equal to 1; and an array of sensitive surfaces each formed of receptors with which the analytes are able to interact by adsorption/desorption and arranged periodically and hexagonally.

公开(公告)号：US11447387B2

公开(公告)日：2022-09-20

申请号：US17296715

申请日：2018-11-29

Applicant: ARYBALLE

Inventor： Didier Jost ,  Alan Jost ,  Frederic Rustanys

IPC: B67D7/34 ,  G01N33/00

Abstract: Dispensing device including a dispensing conduit configured to convey a liquid between a supply source and a tank, the dispensing conduit including a closure system having an open state and a closed state, an analysis system including an analysis chamber and an odor sensor, a central electronic system capable of placing the closure system in the open state if an odor signal delivered by the odor sensor matches the odor of the liquid intended to fill the tank, and placing the closure system in the closed state if an odor signal delivered by the odor sensor does not match the odor of the liquid intended to fill the tank.

公开(公告)号：US20250110128A1

公开(公告)日：2025-04-03

申请号：US18727911

申请日：2023-01-11

Applicant: ARYBALLE ,  COMMISSARIAT À L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  UNIVERSITE GRENOBLE ALPES

Inventor： Cristina-Cassiana ANDREI ,  Cyril HERRIER ,  Sami SLIMANI ,  Yanxia HOU-BROUTIN ,  Christophe MOREAU ,  Thierry LIVACHE

IPC: G01N33/569 ,  G01N21/552

Abstract: A method for detecting biological objects by means of an SPR imaging detection system comprising an optical measurement device configured to generate plasmon resonance on a functionalized surface when said surface is exposed to a gas; the method comprising: an assimilation step by exposing the functionalized surface to a sample of interest formed of an aqueous carrier liquid containing the biological objects; a step of removing the liquid in contact with the functionalized surface and exposing the surface to a gas not containing the biological objects, said objects remaining bound to the ligands of the sensitive site of the functionalized surface; a step of acquiring an image of the sensitive site; a step of detecting the biological objects from the acquired image.

公开(公告)号：US20240175853A1

公开(公告)日：2024-05-30

申请号：US18549403

申请日：2022-03-04

Applicant: ARYBALLE

Inventor： Pierre Maho

IPC: G01N33/00 ,  G01N21/552

CPC classification number: G01N33/0059 ,  G01N21/553 ,  G01N33/0021

Abstract: A method for characterizing an analyte A present in a gas sample using an electronic nose including M sensitive site, a parasitic chemical species P being present in the gas sample, the method include: a phase 100 of acquiring N first signatures, where N>1, of the gas samples containing the analyte A and the parasitic species P, the gas samples exhibiting deviations ΔcP(n) which differ from one gas sample to the next; a phase 200 of solving an optimization problem so as to obtain N corrected signatures, characterising the analyte A present in the N gas samples, from the N first signatures, by optimizing to objective functions.

公开(公告)号：US20230032568A1

公开(公告)日：2023-02-02

申请号：US17791768

申请日：2021-01-08

Applicant: ARYBALLE

Inventor： Kirill ARKHIPOV

IPC: G01N21/552 ,  G01N21/27 ,  G01N33/00

Abstract: An electronic device for assessing a state of a product likely to transform by emission of volatile organic compounds includes olfactory sensors, designed to provide signals representative of a presence of volatile organic compounds in the ambient air close to the product, and a processor for processing the provided signals to obtain a signature representative of the state of the product. It further includes a memory for storing a reference signature, representative of an exposure of the olfactory sensors to a reference humid environment in which the product is not present, and a computer which computes a similarity value for similarity between the signature representative of the state of the product and the reference signature, to provide a product transformation index value from the computed similarity value.

公开(公告)号：US20220120682A1

公开(公告)日：2022-04-21

申请号：US17419463

申请日：2019-12-28

Applicant: ARYBALLE TECHNOLOGIES

Inventor： Yanis Caritu ,  Kirill Arkhipov

IPC: G01N21/552 ,  G01N21/77

Abstract: Disclosed is a method for characterizing target compounds using an analyzing system comprising a measurement chamber intended to receive the target compounds contained in a fluid sample and in which a plurality of separate sensitive sites each comprise receivers able to interact with the target compounds. The method includes supplying a fluid sample, determining a measurement signal Sk(ti) representative of the interactions between the target compounds and the receivers; computing a normed vector Sn(ti); and reiterating the determining and computing steps, while incrementing the measurement time, until a stability criterion is met, so as to obtain a characterization of the target compounds from the normed vector Sn(ti).

公开(公告)号：US10928369B2

公开(公告)日：2021-02-23

申请号：US16490527

申请日：2018-03-02

Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  UNIVERSITE GRENOBLE ALPES ,  ARYBALLE TECHNOLOGIES

Inventor： Cyril Herrier ,  Yanxia Hou-Broutin ,  Francois-Xavier Gallat ,  Thierry Livache ,  Tristan Rousselle

IPC: G01N33/00 ,  G01N21/41 ,  G01N21/552 ,  G01N21/61

Abstract: The invention relates to a method for calibrating an electronic nose, said electronic nose comprising a plurality of optical sensors arranged on a surface and capable of being in contact with a gaseous medium of interest, said optical sensors being capable of delivering a signal representative of the local optical index of the gaseous medium of interest when they are excited by photons, the method being characterized in that it comprises the following steps: after having placed the electronic nose in a gaseous medium of interest at the initial pressure (P0) and the initial temperature (T0): a) sending photons in the direction of the sensors so as to excite said sensors; b) measuring the signal delivered by each of the sensors, this measurement providing as many responses as there are sensors; c) modifying the pressure and/or temperature of the gaseous medium of interest; d) repeating step b); and e) for each sensor, determining a correction factor such as a variation in the signal between steps d) and b) corrected by the correction factor either equal to or substantially equal to a variation in the signal between these same steps for a reference, said reference being provided by a reference sensor or a combination of reference sensors. Such a method allows a physical calibration, that in the present case is relative, to be performed between the different sensors.

公开(公告)号：US11953483B2

公开(公告)日：2024-04-09

申请号：US17442201

申请日：2020-03-25

Applicant: ARYBALLE

Inventor： Thierry Livache ,  Cyril Herrier ,  Romain Dubreuil

IPC: G01N33/00

CPC classification number: G01N33/007

Abstract: A method determines a potential poisoning of a sensor of an electronic nose by a volatile compound following an exposure of the sensor to a gaseous sample including at least this volatile compound. If there is poisoning, the method determines whether the sensor is still functional such that the sensor is still capable of carrying out one or a plurality of reliable measurements, or on the contrary, whether the sensor is saturated and must no longer be used. The method may be used with any type of electronic nose.

公开(公告)号：US20230243754A1

公开(公告)日：2023-08-03

申请号：US18009763

申请日：2021-06-14

Applicant: ARYBALLE

Inventor： Thierry CHAVIGNER

IPC: G01N21/77 ,  G01N29/12

CPC classification number: G01N21/7703 ,  G01N29/12 ,  G01N2291/023 ,  G01N2021/7779

Abstract: The invention relates to an electronic device for analyzing an analyte (2) present in a fluid, comprising: a consumable and interchangeable sensor (10) comprising temporary receptors (14) capable of an interaction with the analyte present in the fluid, causing a change in local property; a sensor holder (50) in which the sensor is intended to be reversibly placed; and a transducer for the change in local property (130, 131; 230, 231), positioned on the sensor and/or on the sensor holder and able to convert the change in local property into an electronic signal expressing the change in local property. The sensor comprises a protection (17) for the temporary receptors. The invention also relates to the method of manufacturing this device, as well as to the consumable and interchangeable sensor and to its method of manufacturing.