公开(公告)号：US20110056844A1

公开(公告)日：2011-03-10

申请号：US12872735

申请日：2010-08-31

Applicant: Hiroshi AOKI ,  Hiroaki TAO ,  Akiko KITAJIMA

Inventor： Hiroshi AOKI ,  Hiroaki TAO ,  Akiko KITAJIMA

IPC: G01N27/26 ,  G01N27/30

CPC classification number: G01N33/542 ,  G01N2458/30

Abstract: Constitute a molecular recognition probe comprising: an electrochemically active group; an activity suppression group that suppresses an electrochemical activity of the electrochemically active group; a receptor area where a molecule of a target substance is specifically recognized; and a molecule area where a steric structure is changed as a result of molecular recognition; wherein the electrochemically active group is suppressed of its activity by the activity suppression group before the molecule is recognized and restores its activity after the molecule is recognized; or constitute a molecular recognition sensor by providing an anchor area on the molecular recognition probe and fixing it on a surface of an electrode.

Abstract translation: 构成分子识别探针，其包含：电化学活性基团; 抑制电化学活性基团的电化学活性的活性抑制基团; 特异性识别目标物质分子的受体区域; 以及分子识别结果改变空间结构的分子区域; 其中所述电化学活性基团在分子被识别之前被活性抑制基团抑制其活性，并且在分子被识别后恢复其活性; 或通过在分子识别探针上提供锚定区域并将其固定在电极的表面上来构成分子识别传感器。

公开(公告)号：US08454820B2

公开(公告)日：2013-06-04

申请号：US12872735

申请日：2010-08-31

Applicant: Hiroshi Aoki ,  Hiroaki Tao ,  Akiko Kitajima

Inventor： Hiroshi Aoki ,  Hiroaki Tao ,  Akiko Kitajima

IPC: G01N27/327

CPC classification number: G01N33/542 ,  G01N2458/30

Abstract: Constitute a molecular recognition probe comprising: an electrochemically active group; an activity suppression group that suppresses an electrochemical activity of the electrochemically active group; a receptor area where a molecule of a target substance is specifically recognized; and a molecule area where a steric structure is changed as a result of molecular recognition; wherein the electrochemically active group is suppressed of its activity by the activity suppression group before the molecule is recognized and restores its activity after the molecule is recognized; or constitute a molecular recognition sensor by providing an anchor area on the molecular recognition probe and fixing it on a surface of an electrode.

Abstract translation: 构成分子识别探针，其包含：电化学活性基团; 抑制电化学活性基团的电化学活性的活性抑制基团; 特异性识别目标物质分子的受体区域; 以及分子识别结果改变空间结构的分子区域; 其中所述电化学活性基团在分子被识别之前被活性抑制基团抑制其活性，并且在分子被识别后恢复其活性; 或通过在分子识别探针上提供锚定区域并将其固定在电极的表面上来构成分子识别传感器。