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    Dermocosmetic Preparations
    4.
    发明申请
    Dermocosmetic Preparations 审中-公开
    皮肤科药物制剂

    公开(公告)号：US20080220031A1

    公开(公告)日：2008-09-11

    申请号：US11996424

    申请日：2006-07-14

    Applicant: Thomas Wunsch ,  Sylke Haremza ,  Axel Jentzsch ,  Gerhard Wagenblast

    Inventor： Thomas Wunsch ,  Sylke Haremza ,  Axel Jentzsch ,  Gerhard Wagenblast

    IPC: A61K8/49 ,  A61Q5/00 ,  A61Q19/00 ,  A61K8/06

    CPC classification number: A61K8/4926 ,  A61K8/817 ,  A61K2800/522 ,  A61Q1/02 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/12 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/002 ,  A61Q19/004 ,  A61Q19/10

    Abstract: The present invention relates to dermocosmetic compositions comprising a compound comprising the structural element of the formula I where the radical Z has the following meaning: H, C1-C22alkyl group, C6-C10-aryl group, C1-C22-alkoxy group or a C6-C10-O-aryl group substituted by a C1-C22-alkyl or C-C22-alkoxy group,and the radicals R1 to R6, independently of one another, have the following meaning: H, C1-C22-alkyl group, C6-C10-aryl group, O, OH, C1-C22-alkoxy group or a C6-C10-O-aryl group substituted by a C1-C22-alkyl or C1-C22-alkoxy group,it being possible for R5 and R6 to be bridged in such a way that a five- to eight-membered ring is formed and, in the case of a five-membered ring, this ring may be part of an oligomer as a result of covalent bonds at positions 3 and 4.The invention furthermore relates to the use of said compounds in dermocosmetic formulations and the use of the dermocosmetics according to the invention for reducing skin or hair damage caused by free radicals. The invention furthermore relates to the use of the compounds according to the invention for increasing the stability of dermocosmetic formulations.

    Abstract translation: 本发明涉及皮肤科药物组合物，其包含包含式I结构元素的化合物，其中基团Z具有以下含义：H，C 1 -C 22烷基 C 6 -C 10 - 芳基，C 1 -C 22 - 烷氧基或C 1 -C 12 - 被C 1 -C 22 -C 22 - 烷基取代的芳基或CC 22个 - 烷氧基，基团R 1至R 6彼此独立地具有如下含义：H，C 1 C 22 - - - 烷基，C 6 -C 10 - 芳基，O，OH，C 1 -C 22 - 烷氧基或被C 1 -C 6烷基取代的C 6 -C 10 -C 10 -O-芳基， C 1 -C 22烷基或C 1 -C 22 - 烷氧基，可以是R 5 和R 6以桥接形式形成五至八元环，并且在五元环的情况下， 由于位置3和4的共价键，s环可以是低聚物的一部分。本发明还涉及所述化合物在皮肤科药物制剂中的用途以及根据本发明的皮肤用品用于减少皮肤或毛发损伤的用途 由自由基。 本发明还涉及根据本发明的化合物用于增加皮肤科药物制剂的稳定性的用途。

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