中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

5 records (took 0.016 seconds)

    Assessment method
    1.
    发明申请
    Assessment method 审中-公开
    评估方法

    公开(公告)号：US20070059696A1

    公开(公告)日：2007-03-15

    申请号：US10549557

    申请日：2004-03-19

    Applicant: Sandra Ebert ,  Michael Uwe ,  Roland Nau ,  David De Kretser ,  David Phillips

    Inventor： Sandra Ebert ,  Michael Uwe ,  Roland Nau ,  David De Kretser ,  David Phillips

    IPC: C12Q1/68 ,  G01N33/53

    CPC classification number: G01N33/6893 ,  G01N2333/495

    Abstract: The present invention relates generally to a method of diagnosing, predicting and/or monitoring the development or progress of an inflammatory response in a mammal. More particularly, the present invention relates to a method of diagnosing, predicting and/or monitoring the development or progress of an inflammatory response by analysing one or both of activin or follistatin expression levels either in a subject mammal or in a biological sample derived from said mammal. The present invention further provides a method for predicting, diagnosing and/or monitoring conditions associated with or characterised by the onset of inflammatory response. Also provided are diagnostic agents useful for detecting activin and/or follistatin expression levels.

    Abstract translation: 本发明一般涉及诊断，预测和/或监测哺乳动物炎症反应的发展或进展的方法。 更具体地说，本发明涉及通过分析受试哺乳动物或衍生自所述哺乳动物的生物样品中的活化素或卵泡抑素表达水平中的一种或两种来诊断，预测和/或监测炎症反应的发展或进展的方法 哺乳动物。 本发明还提供了一种用于预测，诊断和/或监测与炎性反应发作相关或特征在于其发作的病症的方法。 还提供了用于检测激活素和/或卵泡抑素表达水平的诊断剂。

    Therapeutic Method
    3.
    发明申请
    Therapeutic Method 有权
    治疗方法

    公开(公告)号：US20070248609A1

    公开(公告)日：2007-10-25

    申请号：US10575049

    申请日：2004-10-06

    Applicant: David De Kretser ,  David Phillips ,  Kristian Jones ,  Robyn O'Hehir ,  Shane Patella ,  Kathryn Wilson ,  Kimberly Sebire

    Inventor： David De Kretser ,  David Phillips ,  Kristian Jones ,  Robyn O'Hehir ,  Shane Patella ,  Kathryn Wilson ,  Kimberly Sebire

    IPC: A61K38/18 ,  A61K31/711 ,  A61K39/395 ,  A61K38/17

    CPC classification number: A61K38/1709 ,  C07K16/26

    Abstract: The present invention relates generally to a method of modulating an inflammatory response in a mammal and to agents useful for same. More particularly, the present invention relates to a method of modulating an inflammatory response in a mammal by modulating the functional activity of activin and thereby modulating the pro-inflammatory mediator cascade. The method of the present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by an aberrant, unwanted or otherwise inappropriate inflammatory response including, inter alia, sepsis and inflammation of the airway. The present invention is further directed to methods for identifying and/or designing agents capable of modulating activin mediated regulation of the inflammatory response.

    Abstract translation: 本发明一般涉及一种调节哺乳动物炎症反应的方法以及可用于其的药剂。 更具体地说，本发明涉及通过调节激活素的功能活性从而调节促炎介质级联来调节哺乳动物炎症反应的方法。 本发明的方法尤其可用于治疗和/或预防特征在于异常，不想要的或其它不适当的炎症反应的病症，特别是包括气道的败血症和炎症。 本发明还涉及用于鉴定和/或设计能够调节激活素介导的炎性反应调节的药剂的方法。

    Follistatin isoforms and uses thereof
    5.
    发明申请
    Follistatin isoforms and uses thereof 审中-公开
    Follistatin同种型及其用途

    公开(公告)号：US20070135336A1

    公开(公告)日：2007-06-14

    申请号：US10571837

    申请日：2004-09-15

    Applicant: David De Kretser ,  John Roderick Morrison ,  Shyr-Yeu Lin

    Inventor： David De Kretser ,  John Roderick Morrison ,  Shyr-Yeu Lin

    IPC: A61K38/22

    CPC classification number: A61K38/22 ,  A01K67/0278 ,  A01K2207/15 ,  A01K2217/00 ,  A01K2217/075 ,  A01K2227/105 ,  A01K2267/03 ,  C07K14/4703 ,  C12N15/8509

    Abstract: The present invention relates generally to regulating biological developmental process such as the biological functions involved in such developmental processes including growth and survival of an animal and particularly to methods of modifying the developmental processes and biological functions in cells. The invention also relates to methods of preventing and treating biological-development related conditions by regulating the developmental processes and modifying the biological functions in the cells.

    Abstract translation: 本发明一般涉及调节生物发育过程，例如涉及包括动物生长和存活在内的发育过程的生物学功能，特别涉及修饰细胞发育过程和生物功能的方法。 本发明还涉及通过调节发育过程和改变细胞中生物学功能来预防和治疗生物发育相关病症的方法。

Patent Agency Ranking