公开(公告)号：US06410342B1

公开(公告)日：2002-06-25

申请号：US08914861

申请日：1997-08-19

Applicant: Rhett L. Affleck ,  Doug Hobbs ,  Ilya Feygin ,  Gregory L. Kirk ,  James A. Connelly ,  Ning Zhao ,  James P. Mueller ,  Peter Kieselbach

Inventor： Rhett L. Affleck ,  Doug Hobbs ,  Ilya Feygin ,  Gregory L. Kirk ,  James A. Connelly ,  Ning Zhao ,  James P. Mueller ,  Peter Kieselbach

IPC: G01N33543

CPC classification number: B82Y30/00 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00306 ,  B01J2219/00308 ,  B01J2219/00527 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00659 ,  B01J2219/00711 ,  B01J2219/00713 ,  B01J2219/0072 ,  C07K1/04 ,  C07K1/12 ,  C40B60/14 ,  G01N33/54353

Abstract: A method for photoeluting photocleavable linker-attached chemical compounds, and an apparatus suitable for implementing the method, are disclosed. According to the method, photocleavable linker-attached library compounds are photoeluted from solid support media under conditions of controlled light exposure and controlled temperature. An apparatus suitable for carrying out the present photoelution method includes means for substantially evenly illuminating the photocleavable linker, means for controlling illumination time and intensity, and means for controlling sample temperature.

Abstract translation: 公开了一种光可剥离接头连接的化合物的光洗脱方法，以及适用于实施该方法的装置。 根据该方法，可光裂解的连接物连接的文库化合物在受控的曝光和受控温度的条件下从固体支持介质中光固化。 适用于实施本发明的光洗涤方法的装置包括用于基本均匀地照射可光切割接头的装置，用于控制照明时间和强度的装置，以及用于控制样品温度的装置。

公开(公告)号：US06468787B1

公开(公告)日：2002-10-22

申请号：US09294169

申请日：1999-04-19

Applicant: Rhett L. Affleck ,  Doug Hobbs ,  Ilya Feygin ,  Gregory L. Kirk ,  James A. Connelly ,  Ning Zhao ,  James P. Mueller ,  Peter Kieselbach

Inventor： Rhett L. Affleck ,  Doug Hobbs ,  Ilya Feygin ,  Gregory L. Kirk ,  James A. Connelly ,  Ning Zhao ,  James P. Mueller ,  Peter Kieselbach

IPC: C12M100

CPC classification number: B82Y30/00 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00306 ,  B01J2219/00308 ,  B01J2219/00527 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00659 ,  B01J2219/00711 ,  B01J2219/00713 ,  B01J2219/0072 ,  C07K1/04 ,  C07K1/12 ,  C40B60/14 ,  G01N33/54353

Abstract: A method for photoeluting photocleavable linker-attached chemical compounds, and an apparatus suitable for implementing the method, are disclosed. According to the method, photocleavable linker-attached library compounds are photoeluted from solid support media under conditions of controlled light exposure and controlled temperature. An apparatus suitable for carrying out the present photoelution method includes means for substantially evenly illuminating the photocleavable linker, means for controlling illumination time and intensity, and means for controlling sample temperature.