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公开(公告)号：US11877781B2
公开(公告)日：2024-01-23
申请号：US16149819
申请日：2018-10-02
Applicant: ENDOCARE, INC.
Inventor： Thach Duong , Jay J. Eum
CPC classification number: A61B18/02 , A61B2018/00011 , A61B2018/0212 , A61B2018/0262
Abstract: A cryosurgical probe assembly including a cryosurgical probe having a shaft, an insulation element housed within the cryosurgical probe and being slideably repositionable relative to the shaft, and a fluid supply line having an inlet portion for connection to a cryogenic fluid source.
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公开(公告)号：US20150257810A1
公开(公告)日：2015-09-17
申请号：US14715092
申请日：2015-05-18
Applicant: Endocare, Inc.
Inventor： John M. Baust , Claudia Luekge , Roy Cheeks , John G. Baust , Anthony T. Robilotto
IPC: A61B18/02
CPC classification number: A61B18/02 , A61B2017/00084 , A61B2017/003 , A61B2018/00202 , A61B2018/00208 , A61B2018/00577 , A61B2018/00797 , A61B2018/0212
Abstract: One embodiment of the invention is a flexible cryogenic probe tip. The flexible probe tip has a linear freeze zone at a distal end of the probe that allows for its placement and precisely controlled movements. The flexible cryogenic probe tip precisely conforms to the target tissue surface to create a linear lesion. In addition, the probe tip is steerable to facilitate proper placement with minimal access points into a patient's body. Various configurations of the flexible probe tip allow it to conform and ablate tissue of many sizes, shapes, and/or dimensions. Methods of utilizing the cryogenic probe tip include steps of positioning the distal end at a tissue site for at least one ablative procedure, maneuvering the distal end to the tissue site, directing a cryogen from the supply source to the distal end, controlling a flow of cryogen from the supply source to the distal end and back to the supply source, and segmenting control of the distal end mechanically or through the step of controlling the flow of cryogen.
Abstract translation: 本发明的一个实施例是柔性低温探针尖端。 柔性探针尖端在探头的远端具有允许其放置和精确控制运动的线性冻结区。 柔性低温探针尖端精确地符合目标组织表面以产生线性损伤。 此外，探针尖是可操纵的，以便于以最小的接入点进入患者身体的正确放置。 柔性探针尖端的各种构造允许其适应并消融许多尺寸，形状和/或尺寸的组织。 使用低温探针尖端的方法包括以下步骤：将远端定位在组织部位处至少一个烧蚀程序，将远端操纵到组织部位，将冷冻剂从供应源引导到远端，控制流动 冷冻剂从供应源到远端并返回到供应源，并且机械地或通过控制冷冻剂流动的步骤来分段远端的控制。
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公开(公告)号：US11026737B2
公开(公告)日：2021-06-08
申请号：US14213441
申请日：2014-03-14
Applicant: ENDOCARE, INC.
Inventor： John G. Baust , John M. Baust , Anthony T. Robilotto
Abstract: Embodiments of the present invention relate to cryogenic systems and methods useful to cool objects, including living tissue, to freezing or cryogenic temperatures by placing the object in thermal communication with sub-cooled supercritical nitrogen.
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公开(公告)号：US20170224401A1
公开(公告)日：2017-08-10
申请号：US15581218
申请日：2017-04-28
Applicant: Endocare, Inc.
Inventor： John M. Baust , John G. Baust , Roy E. Cheeks , Anthony Robilotto
CPC classification number: A61B18/02 , A61B17/29 , A61B18/1445 , A61B2017/00212 , A61B2017/00398 , A61B2017/00539 , A61B2017/00544 , A61B2017/2932 , A61B2018/00101 , A61B2018/00714 , A61B2018/00791 , A61B2018/00839 , A61B2018/0212 , A61B2018/0225 , A61B2018/0262 , A61B2090/064 , A61B2090/0811
Abstract: A cryogenic medical device is disclosed for use in minimally invasive surgical procedures. Various configurations of cryoprobes are designed in combination with a clamp to form a cryoclamp for the treatment of damaged, diseased, cancerous or other unwanted tissues. The device is an integrated cryoablation probe with a hinged clamp that allows for single entry into the chest cavity through a thorascopic port, by surgical or other means. The integrated cryoablation probe allows for the clamping of tissue as well as freezing with a single device. The clamp acts as an outer sheath so that when closed, directional freezing of the cryoprobe is achieved on the opposing probe surface away from the clamp or on an internal surface that is between the clamp. The cryoclamp may be a removable attachment or integrated into the unitary device.
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公开(公告)号：US09724150B1
公开(公告)日：2017-08-08
申请号：US13731639
申请日：2012-12-31
Applicant: ENDOCARE, INC.
Inventor： Shenghao Bao , Jay J. Eum
CPC classification number: A61B18/0218 , A61B5/0008 , A61B5/01 , A61B8/0841 , A61B8/085 , A61B8/0858 , A61B8/4254 , A61B8/4263 , A61B8/4416 , A61B8/5223 , A61B8/5238 , A61B8/5253 , A61B8/546 , A61B18/02 , A61B34/10 , A61B2017/00274 , A61B2018/00011 , A61B2018/00511 , A61B2018/00529 , A61B2018/00547 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00982 , A61B2034/104 , A61B2090/378
Abstract: A cryosurgical system including a computer system programmed with software configured to perform the following steps: a) capturing at least one first view of a region of interest in a human body; b) capturing at least one second view of the region of interest; c) outlining the region of interest and at least one area outside the region of interest with the assistance of an operator; d) constructing a 3-dimensional model of the region of interest and the at least one area outside the region of interest utilizing the at least one first view and the at least one second view of the region of interest; and e) utilizing the 3-dimensional model of the region of interest and the at least one area outside the region of interest to determine at least one cryosurgical probe placement location.
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Patent Agency Ranking
公开(公告)号：US20140350537A1
公开(公告)日：2014-11-27
申请号：US14213441
申请日：2014-03-14
Applicant: ENDOCARE, INC.
Inventor： John G. Baust , John M. Baust , Anthony T. Robilotto
IPC: A61B18/02
CPC classification number: A61B18/02 , A61B2018/00023 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262 , A61B2018/0293
Abstract: Embodiments of the present invention relate to cryogenic systems and methods useful to cool objects, including living tissue, to freezing or cryogenic temperatures by placing the object in thermal communication with sub-cooled supercritical nitrogen.
Abstract translation: 本发明的实施方案涉及通过将物体与次冷的超临界氮热连通来将低温系统和方法用于将物体（包括活组织）冷却至冷冻或低温的温度。
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公开(公告)号：US20220211423A9
公开(公告)日：2022-07-07
申请号：US16149819
申请日：2018-10-02
Applicant: ENDOCARE, INC.
Inventor： THACH DUONG , JAY J. EUM
IPC: A61B18/02
Abstract: A cryosurgical probe assembly including a cryosurgical probe having a shaft, an insulation element housed within the cryosurgical probe and being slideably repositionable relative to the shaft, and a fluid supply line having an inlet portion for connection to a cryogenic fluid source.
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公开(公告)号：US10828105B2
公开(公告)日：2020-11-10
申请号：US15128372
申请日：2015-03-23
Applicant: ENDOCARE, INC.
Inventor： Alind Sahay , Robert J. Riker , Cristian Atria
Abstract: A system for assisting a surgeon in placing at least one ablation device into a treatment region of a patient, where the system includes at least one computer system having a display, a user interface and software, is described. The system uses patient image data of the treatment region to generate an image of the treatment region on the display and identifies the treatment region to ablate with a target. Tissue properties of the treatment region are identified and used to perform thermal modeling. Treatment parameters are generated and an ablation zone is calculated. A computer system display is generated showing (a) the number of ablation devices required to ablate the treatment region and the location and orientation of each ablation device in the treatment region and (b) the ablation zone.
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公开(公告)号：US20200030018A1
公开(公告)日：2020-01-30
申请号：US16593914
申请日：2019-10-04
Applicant: Endocare, Inc.
Inventor： John M. Baust , Claudia Lueckge , Roy Cheeks , John G. Baust , Anthony T. Robi
IPC: A61B18/02
Abstract: An ablation instrument having a longitudinal body with a plurality of sidewalls that form a flexible sleeve, where the plurality of sidewalls that form the flexible sleeve are slotless. The longitudinal body has a proximal end, a distal end, and a central axis. A luminary space is formed within the plurality of sidewalls and at least one internal component is inserted through the proximal end of the longitudinal body and extends through the luminary space to the distal end. The internal component is interconnected with a deflection mechanism for controlling the distal end of the longitudinal body such that the distal end is capable of multi-planar movement.
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公开(公告)号：US09974592B2
公开(公告)日：2018-05-22
申请号：US14808750
申请日：2015-07-24
Applicant: Endocare, Inc.
Inventor： John M. Baust , John G. Baust , Roy E. Cheeks , Melissa K. Dobson , Anthony T. Robilotto , Kristi K. Snyder , Robert G. Van Buskirk
CPC classification number: A61B18/02 , A61B2018/00041 , A61B2018/00357 , A61B2018/00577 , A61B2018/00791 , A61B2018/00863 , A61B2018/00982 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262 , F04C2270/0421
Abstract: Cryogenic medical devices and apparatus are disclosed which are capable of generating cryogen to a supercritical state, specifically supercritical nitrogen. The cryogenic medical devices and apparatus disclosed are useful in methods of treating damaged, diseased, cancerous or other unwanted tissues.
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