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1.
公开(公告)号:US20100160371A1
公开(公告)日:2010-06-24
申请号:US12619913
申请日:2009-11-17
Applicant: Gerald RANGES , William Scott , Michael Bombara , Deborah Rauner , Aniko Redman , Roger Smith , Holger Paulsen , David Gunn , Jinshan Chen , Joel Renick
Inventor: Gerald RANGES , William Scott , Michael Bombara , Deborah Rauner , Aniko Redman , Roger Smith , Holger Paulsen , David Gunn , Jinshan Chen , Joel Renick
IPC: A61K31/381 , A61K31/341 , A61K31/40 , A61K31/433 , A61K31/47 , A61K31/404 , A61P29/00 , A61P37/00 , A61P19/10 , A61P11/06
CPC classification number: A61K31/4709 , A61K31/341 , A61K31/381 , A61K31/40 , A61K31/4025 , A61K31/433 , Y02A50/401 , Y02A50/411 , Y02A50/414
Abstract: This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical compositions for use in such therapy.
Abstract translation: 本发明涉及一组芳基脲在治疗癌症以外的细胞因子介导的疾病和除了癌症以外的蛋白水解酶介导的疾病以及用于这种治疗的药物组合物中的用途。
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公开(公告)号:US08168758B2
公开(公告)日:2012-05-01
申请号:US12086320
申请日:2006-12-12
Applicant: Paul Tamburini , Gerald Ranges , Lila Adnane , Timothy Mccabe , Pamela Trail , Sha Ha
Inventor: Paul Tamburini , Gerald Ranges , Lila Adnane , Timothy Mccabe , Pamela Trail , Sha Ha
IPC: C12P21/08
CPC classification number: C07K16/40 , A61K39/395 , A61K47/6803 , A61K47/6817 , A61K47/6851 , A61K47/6871 , A61K2039/505 , C07K16/30 , C07K2317/21 , C07K2317/55 , C07K2317/565 , C07K2317/732 , C07K2317/77 , C07K2317/92 , A61K2300/00
Abstract: The invention provides antibodies having an antigenic binding site specifically directed against an MN protein, and methods for using such antibodies in treating and diagnosing an MN-related disorder.
Abstract translation: 本发明提供具有针对MN蛋白特异性抗原结合位点的抗体,以及使用这些抗体治疗和诊断MN相关病症的方法。
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公开(公告)号:US06344476B1
公开(公告)日:2002-02-05
申请号:US09083396
申请日:1998-05-22
Applicant: Gerald Ranges , William Scott , Michael Bombara , Deborah Rauner , Aniko Redman , Roger Smith , Holger Paulsen , David Gunn , Jinshan Chen , Joel Renick
Inventor: Gerald Ranges , William Scott , Michael Bombara , Deborah Rauner , Aniko Redman , Roger Smith , Holger Paulsen , David Gunn , Jinshan Chen , Joel Renick
IPC: A61K3138
CPC classification number: A61K31/4709 , A61K31/341 , A61K31/381 , A61K31/40 , A61K31/4025 , A61K31/433 , Y02A50/411 , Y02A50/414
Abstract: This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical compositions for use in such therapy.
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公开(公告)号:US20120301468A1
公开(公告)日:2012-11-29
申请号:US13459558
申请日:2012-04-30
Applicant: Paul Tamburini , Gerald Ranges , Lila Adnane , Timothy McCabe , Pamela Trail , Sha Ha
Inventor: Paul Tamburini , Gerald Ranges , Lila Adnane , Timothy McCabe , Pamela Trail , Sha Ha
IPC: C07K16/30 , G01N33/574 , A61P35/00 , A61K39/395
CPC classification number: C07K16/40 , A61K39/395 , A61K47/6803 , A61K47/6817 , A61K47/6851 , A61K47/6871 , A61K2039/505 , C07K16/30 , C07K2317/21 , C07K2317/55 , C07K2317/565 , C07K2317/732 , C07K2317/77 , C07K2317/92 , A61K2300/00
Abstract: The invention provides antibodies having an antigenic binding site specifically directed against an MN protein, and methods of using such antibodies in treating and diagnosing an MN-related disorder.
Abstract translation: 本发明提供具有特异性针对MN蛋白的抗原结合位点的抗体,以及使用这些抗体治疗和诊断MN相关病症的方法。
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公开(公告)号:US20100129315A1
公开(公告)日:2010-05-27
申请号:US12086320
申请日:2006-12-12
Applicant: Paul Tamburini , Gerald Ranges Hamden , Lila Adnane , Timothy McCabe , Pamela Trail , Sha Ha
Inventor: Paul Tamburini , Gerald Ranges Hamden , Lila Adnane , Timothy McCabe , Pamela Trail , Sha Ha
CPC classification number: C07K16/40 , A61K39/395 , A61K47/6803 , A61K47/6817 , A61K47/6851 , A61K47/6871 , A61K2039/505 , C07K16/30 , C07K2317/21 , C07K2317/55 , C07K2317/565 , C07K2317/732 , C07K2317/77 , C07K2317/92 , A61K2300/00
Abstract: The invention provides antibodies having an antigenic binding site specifically directed against an MN protein, and methods for using such antibodies in treating and diagnosing an MN-related disorder.
Abstract translation: 本发明提供具有针对MN蛋白特异性抗原结合位点的抗体,以及使用这些抗体治疗和诊断MN相关病症的方法。
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