公开(公告)号：US20250166483A1

公开(公告)日：2025-05-22

申请号：US19031414

申请日：2025-01-18

Applicant: Howard Levin

Inventor： Howard Levin

IPC: G08B21/18

Abstract: A system, method, and apparatus are provided to facilitate social distancing. The system issues alarms based on the distance between a user and an object and one or more variable social distancing thresholds. The system enables trade-offs between risk and a desire to have in-person interaction for different activities by using one or more variable social distancing thresholds that may be based on social distancing guidelines and various characteristics. The system may include penalties and rewards to incentivize adherence to social distancing guidelines.

公开(公告)号：US12243407B2

公开(公告)日：2025-03-04

申请号：US18215889

申请日：2023-06-29

Applicant: Howard Levin

Inventor： Howard Levin

IPC: G08B21/18

Abstract: A system, method, and apparatus are provided to facilitate social distancing. The system issues alarms based on the distance between a user and an object and one or more variable social distancing thresholds. The system enables trade-offs between risk and a desire to have in-person interaction for different activities by using one or more variable social distancing thresholds that may be based on social distancing guidelines and various characteristics.

公开(公告)号：US20160324563A1

公开(公告)日：2016-11-10

申请号：US15214222

申请日：2016-07-19

Applicant: Mark GELFAND ,  Howard LEVIN

Inventor： Mark GELFAND ,  Howard LEVIN

IPC: A61B18/02 ,  A61M25/00 ,  A61B18/14

CPC classification number: A61B18/0218 ,  A61B18/1492 ,  A61B18/18 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00279 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00404 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00714 ,  A61B2018/00791 ,  A61B2018/0212 ,  A61B2018/0225 ,  A61B2018/0293 ,  A61B2018/1407 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/3784 ,  A61M25/0082

Abstract: Systems, devices, and methods for treating a patient having a sympathetically mediated disease associated at least in part with augmented peripheral chemoreflex or heightened sympathetic activation. The treatments include ablating one or more peripheral chemoreceptors or associated afferent nerves to reduce or remove afferent neural signals from the peripheral chemoreceptor.

Abstract translation: 用于治疗患有交感神经介导的疾病的患者的系统，装置和方法至少部分地与增加的外周化学反应或增强的交感神经激活相关联。 治疗包括消融一种或多种外周化学感受器或相关传入神经以减少或消除来自外周化学感受器的传入神经信号。

公开(公告)号：US20130324989A1

公开(公告)日：2013-12-05

申请号：US13908995

申请日：2013-06-03

Applicant: Mark Leung ,  Brett Schleicher ,  Charles Lennox ,  Ary Chernomorsky ,  Zoar Jacob Engelman ,  Marat Fudim ,  Martin M. Grasse ,  Mark Gelfand ,  Howard Levin

Inventor： Mark Leung ,  Brett Schleicher ,  Charles Lennox ,  Ary Chernomorsky ,  Zoar Jacob Engelman ,  Marat Fudim ,  Martin M. Grasse ,  Mark Gelfand ,  Howard Levin

IPC: A61B18/02

CPC classification number: A61B18/02 ,  A61B8/0841 ,  A61B8/0891 ,  A61B8/12 ,  A61B8/145 ,  A61B8/4227 ,  A61B8/488 ,  A61B18/1477 ,  A61B18/22 ,  A61B90/11 ,  A61B2018/00041 ,  A61B2018/00404 ,  A61B2018/00791 ,  A61B2018/0212 ,  A61B2018/0293 ,  A61B2090/376 ,  A61B2090/3762 ,  A61B2090/378 ,  A61N7/022 ,  A61N2007/0026 ,  F04C2270/0421

Abstract: Methods and percutaneous devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via percutaneous carotid body ablation.

Abstract translation: 用于评估和治疗患有交感神经介导的疾病的患者的方法和经皮装置，通过经由经皮颈动脉体消融将化学传感器输入减少到神经系统，涉及增加的外周化学反应和增强的交感神经紧张。

公开(公告)号：US20120215272A1

公开(公告)日：2012-08-23

申请号：US13426068

申请日：2012-03-21

Applicant: Howard Levin ,  Mark Gelfand

Inventor： Howard Levin ,  Mark Gelfand

IPC: A61N1/362

CPC classification number: A61M25/10181 ,  A61M25/10 ,  A61M25/1018 ,  A61M29/00 ,  A61M2025/102 ,  A61N1/36117 ,  A61N1/3627 ,  A61N1/368 ,  A61N1/37235

Abstract: A method and apparatus for treatment of heart failure by increasing secretion of endogenous naturetic hormones ANP and BNP such as by stimulation of the heart atria. Heart pacing is done at an atrial contraction rate that is increased and can be higher than the ventricular contraction rate. Pacing may include mechanical distension of the right atrial appendage. An implantable device is used to periodically cyclically stretch the walls of the appendage with an implanted balloon.

Abstract translation: 通过增加内源性激素ANP和BNP的分泌来治疗心力衰竭的方法和装置，例如通过刺激心脏心房。 心脏起搏是以增加的心房收缩速率完成的，可以高于心室收缩率。 起搏可能包括右心耳的机械扩张。 使用可植入装置周期性地用植入的气球循环地拉伸附肢的壁。

公开(公告)号：US20110172731A1

公开(公告)日：2011-07-14

申请号：US12987498

申请日：2011-01-10

Applicant: Howard Levin ,  Mark Gelfand

Inventor： Howard Levin ,  Mark Gelfand

IPC: A61N1/365

CPC classification number: A61N1/3627 ,  A61B5/0452 ,  A61N1/3624 ,  A61N1/368 ,  A61N1/3684 ,  A61N1/37235

Abstract: A method and apparatus for treatment of hypertension and heart failure by increasing vagal tone and secretion of endogenous atrial hormones by excitory pacing of the heart atria. Atrial pacing is done during the ventricular refractory period resulting in atrial contraction against closed AV valves, and atrial contraction rate that is higher than the ventricular contraction rate. Pacing results in the increased atrial wall stress. An implantable device is used to monitor ECG and pace the atria in a nonphysiologic manner.

Abstract translation: 一种通过增加迷走神经张力和通过心脏心房的兴奋性起搏分泌内源性心房激素来治疗高血压和心力衰竭的方法和装置。 心房起搏在心室不应期内完成，导致闭合性AV瓣膜的心房收缩，心房收缩率高于心室收缩率。 起搏导致心房壁压力增加。 可植入装置用于监测心电图并以非生理学方式对心房进行加速。

公开(公告)号：US20080097273A1

公开(公告)日：2008-04-24

申请号：US11960145

申请日：2007-12-19

Applicant: Howard Levin ,  Mark Gelfand ,  John O'Mahony ,  Hans-Dietrich Polaschegg

Inventor： Howard Levin ,  Mark Gelfand ,  John O'Mahony ,  Hans-Dietrich Polaschegg

IPC: A61M1/34 ,  A61M1/10

CPC classification number: A61M1/341 ,  A61M1/1692 ,  A61M1/34 ,  A61M1/361 ,  A61M1/3612 ,  A61M2205/3393 ,  A61M2205/50 ,  A61M2205/7563

Abstract: A fluid removal apparatus comprising a blood removal catheter for insertion into a peripheral vein or artery and having a size 16 standard gage needle or less; a filter having a blood inlet port coupled to the blood removal catheter, a blood outlet port, an excess fluid removal port, and a blood flow passage with porous membrane which passes fluids to the fluid removal port and retains solutes of 60,000 Daltons or greater, and a blood return catheter for inserting into a peripheral vein or artery and having a size of 16 standard gage needle or less.

Abstract translation: 一种流体去除装置，包括用于插入到外周静脉或动脉中并具有尺寸16标准规格针或更小的止血导管; 过滤器，其具有联接到除血导管的血液入口端口，血液出口端口，多余的流体移除端口以及具有多孔膜的血流通道，其将流体传递到流体移除端口并保持60,000道尔顿或更大的溶质， 以及用于插入外周静脉或动脉并具有16个标准规格针或更小尺寸的血液回流导管。

公开(公告)号：US20060135912A1

公开(公告)日：2006-06-22

申请号：US11282694

申请日：2005-11-21

Applicant: Ary Chernomorsky ,  Mark Gelfand ,  Howard Levin

Inventor： Ary Chernomorsky ,  Mark Gelfand ,  Howard Levin

IPC: A61M1/00

CPC classification number: A61M25/0084 ,  A61B17/00491 ,  A61B2017/00247 ,  A61B2018/00392

Abstract: A system has been developed for injecting a biodegradable pericardial constraint including: a biodegradable viscoelastic substance (BES); an external injection container for the BES; a cannula having a distal section adapted to be inserted into a pericardial sac of a mammalian heart and a proximal section connectable to the external injection container; wherein BES from the injection container is injected into the pericardial sac through the cannula.

Abstract translation: 已经开发了用于注射可生物降解的心包约束的系统，包括：生物可降解粘弹性物质（BES）; 用于BES的外部注射容器; 套管，其具有适于插入哺乳动物心脏的心包囊中的远端部分和可连接到外部注射容器的近端部分; 其中来自注射容器的BES通过套管被注射到心包囊中。

公开(公告)号：US20210298824A1

公开(公告)日：2021-09-30

申请号：US17304007

申请日：2021-06-11

Applicant: Pajhand IRANITALAB ,  Casey Andrew MILLER ,  Thomas Ryan McGRATH ,  Manuel Arzadon JAVIER ,  Anisha BAPNA ,  Zoar Jacob ENGELMAN ,  Howard LEVIN ,  Nicholas C. VanDILLEN ,  Anne Marie AHONEN

Inventor： Pajhand IRANITALAB ,  Casey Andrew MILLER ,  Thomas Ryan McGRATH ,  Manuel Arzadon JAVIER ,  Anisha BAPNA ,  Zoar Jacob ENGELMAN ,  Howard LEVIN ,  Nicholas C. VanDILLEN ,  Anne Marie AHONEN

IPC: A61B18/14

Abstract: Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are methods of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.

公开(公告)号：US20140243809A1

公开(公告)日：2014-08-28

申请号：US14188452

申请日：2014-02-24

Applicant: Mark GELFAND ,  Howard LEVIN ,  Charles LENNOX ,  Marcus W. WILBORN ,  Paul A. SOBOTKA ,  Zoar Jacob ENGELMAN ,  Martin M. GRASSE ,  Mark S. LEUNG

Inventor： Mark GELFAND ,  Howard LEVIN ,  Charles LENNOX ,  Marcus W. WILBORN ,  Paul A. SOBOTKA ,  Zoar Jacob ENGELMAN ,  Martin M. GRASSE ,  Mark S. LEUNG

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B18/16 ,  A61B2018/00214 ,  A61B2018/00279 ,  A61B2018/00285 ,  A61B2018/00404 ,  A61B2018/00577 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1467 ,  A61B2018/1475 ,  A61B2018/1497 ,  A61B2218/002 ,  A61N7/022

Abstract: Methods, devices, and systems for carotid body modulation via accessing a target site with an endovascular approach through a superficial temporal artery.

Abstract translation: 用于通过浅表颞动脉通过血管内途径进入目标部位进行颈动脉体调节的方法，装置和系统。