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    WIRELESSLY DETECTABLE TAMPER EVIDENT SEAL
    1.
    发明申请
    WIRELESSLY DETECTABLE TAMPER EVIDENT SEAL 审中-公开
    无线检测篡改密封件

    公开(公告)号：US20120261476A1

    公开(公告)日：2012-10-18

    申请号：US13386853

    申请日：2010-07-26

    Applicant: Gary Bortz ,  Jonathan Hugh Elcombe ,  Kevin John Partridge

    Inventor： Gary Bortz ,  Jonathan Hugh Elcombe ,  Kevin John Partridge

    IPC: G06K19/077 ,  B65B51/00 ,  H05K7/00

    CPC classification number: G06K19/07749 ,  G06K19/041 ,  G06K19/07798

    Abstract: A wirelessly detectable tamper-evident seal (1) including a receptacle part (10) and a frangible part (50), the receptacle part (10) including a first receptacle (10a) and a second receptacle (10b-d) attachable to a container to seal a closure of the container and the frangible part (50) including a first portion (51) and a second portion (52) frangibly connected to each other, the first receptacle (10a) adapted to receive the first portion (51) and the second receptacle (10b-d) adapted to receive the second portion (52), the frangible part (50) including a transponder (54), the second portion (52) able to be trapped against movement in the reverse direction in the second receptacle (10b-d) to effect a tamper evident seal between the first and second receptacles (10a-d), wherein the transponder (54) includes at least two circuit interruption locations (94a, 94b) that must be connected to activate the transponder (54) and the transponder (54) is activatable by inserting the second portion (51) in the second receptacle (10b-d) whereby to connect both or all circuit interruption (94a,94b) locations.

    Abstract translation: 一种包括容器部分（10）和易碎部分（50）的无线可检测的防窃启密封件（1），所述容器部分（10）包括第一容器（10a）和第二容器（10b-d） 容器以密封容器的封闭件和易碎部分（50），其包括彼此易碎地连接的第一部分（51）和第二部分（52），适于容纳第一部分（51）的第一容器（10a） 以及适于接收所述第二部分（52）的所述第二容器（10b-d），所述易碎部分（50）包括应答器（54），所述第二部分（52）能够在所述第二部分 第二插座（10b-d），用于在所述第一和第二插座（10a-d）之间实现显窃启密封，其中所述应答器（54）包括必须连接的至少两个电路中断位置（94a，94b） 应答器（54）和应答器（54）可通过插入第二端口来激活 在第二插座（10b-d）中的（51）上，从而连接两个或所有电路中断（94a，94b）位置。

    MICROWAVEABLE PACKAGING FOR FOOD PRODUCTS INCLUDING A FROZEN COMPONENT
    2.
    发明申请
    MICROWAVEABLE PACKAGING FOR FOOD PRODUCTS INCLUDING A FROZEN COMPONENT 有权
    包括冷冻组件的食品的微波包装

    公开(公告)号：US20120205366A1

    公开(公告)日：2012-08-16

    申请号：US13372343

    申请日：2012-02-13

    Applicant: Animequom Adams ,  Hunter Gartner ,  John Partridge ,  Janice Harte ,  Keith Emery

    Inventor： Animequom Adams ,  Hunter Gartner ,  John Partridge ,  Janice Harte ,  Keith Emery

    IPC: H05B6/80

    CPC classification number: H05B6/6408

    Abstract: Packaging and a dessert food product combines a hot portion and a cold portion. In one embodiment, the dessert combines hot pie with a topping of ice cream in a single package. In one aspect of the invention, the microwaveable food product and package incorporates a food package that simultaneously includes various susceptor films that allow for differential heating of food. The susceptor film(s) shield the cold-portion food products from being heated in the microwave while they provide even heating of the hot portion of the product. The packaging provides a quick, convenient and tasty dessert with minimal effort. In another aspect of the present invention, the pie and ice cream formulation has been optimized to maintain superior flavor and texture properties after freezing and microwave reheating.

    Abstract translation: 包装和甜点食品结合了热部分和冷部分。 在一个实施方案中，甜点将热馅饼与单个包装中的冰淇淋顶部组合。 在本发明的一个方面，可微波食品和包装包括食品包装，其同时包括允许差别加热食物的各种感受器膜。 感光薄膜可以防止冷部分食物在微波炉中被加热，同时它们可以均匀地加热产品的热部分。 包装提供了一个快速，方便和美味的甜点，最小的努力。 在本发明的另一方面，馅饼和冰淇淋配方已被优化以在冷冻和微波加热之后保持优异的风味和质地特性。

    A1 Adenosine Receptor Antagonists
    5.
    发明申请
    A1 Adenosine Receptor Antagonists 审中-公开
    A1腺苷受体拮抗剂

    公开(公告)号：US20070274910A1

    公开(公告)日：2007-11-29

    申请号：US10560853

    申请日：2004-06-07

    Applicant: Constance Wilson ,  John Partridge

    Inventor： Constance Wilson ,  John Partridge

    IPC: A61K31/522

    CPC classification number: C07D473/06

    Abstract: This invention relates to compounds of formula (I): wherein R1 is a branched or straight chain C1-C6 alkyl; R2 is of the formula (II), wherein n is an integer ranging from 1 to 8; R5 is H or (CH2)pCH3, and R6 is H or (CH2)mOH, wherein p is an integer ranging from 1 to 7 and m is an integer ranging from 1 to 8; R3 is of the formula (III), wherein q is an integer ranging from 1 to 8; and R7 is selected from the group consisting of H, OH, NH2, (CH2)tOH, and R9COOH; wherein R9 is a straight or branched chain alkylene or alkenylene group having 1 to 8 carbon atoms, and t is an integer ranging from 1 to 8; R4 is of the formula (IV), wherein r is an integer ranging from 1 to 8 and R8 is selected from the group consisting of H, OH, (CH2)fNH2, (CH2)sOH, and R10COOH; wherein f is 0 or f and s are independently integers ranging from 1 to 8; and, R10 is a C1-C8 straight or branched chain alkylene or alkenylene; and; salts, solvates, and hydrates thereof. The present invention further provides methods of preparing the compounds of formula (I) and their use as therapeutic agents and diagnostic agents.

    Abstract translation: 本发明涉及式（I）化合物：其中R 1是支链或直链C 1 -C 6烷基; R 2具有式（II），其中n是1至8的整数; R 5是H或（CH 2）2 CH 3 CH 3，和R 6 是H或（CH 2 CH 2）m OH，其中p是1至7的整数，m是1至8的整数; R 3具有式（III），其中q是1至8的整数; 和R 7选自H，OH，NH 2，（CH 2）2， OH和R 9 COOH; 其中R 9是具有1至8个碳原子的直链或支链亚烷基或亚烯基，t是1至8的整数; R 4具有式（IV）的化合物，其中r是1至8的整数，R 8选自H，OH，（CH NH 2，（CH 2）n OH，R 2，R 2，R 2， 10 COOH; 其中f为0或f且s为独立地为1至8的整数; 且R 10是C 1 -C 8直链或支链亚烷基或亚烯基; 和; 盐，溶剂化物和水合物。 本发明还提供制备式（I）化合物及其作为治疗剂和诊断剂的用途的方法。

    Compositions and methods for treating respiratory disorders
    6.
    发明申请
    Compositions and methods for treating respiratory disorders 审中-公开
    用于治疗呼吸系统疾病的组合物和方法

    公开(公告)号：US20070219223A1

    公开(公告)日：2007-09-20

    申请号：US11715089

    申请日：2007-03-07

    Applicant: Constance Wilson ,  John Partridge

    Inventor： Constance Wilson ,  John Partridge

    IPC: A61K31/522 ,  C07D473/04

    CPC classification number: C07D473/04 ,  A61K31/522 ,  C07D473/06

    Abstract: Methods and compositions for treating and preventing respiratory disorders are provided. The methods of the invention comprise administering to a subject a therapeutically effective amount of a pharmaceutically acceptable salt of an A1 adenosine receptor antagonist, particularly 1-hydroxy-2-naphthoic acid salts or 3-hydroxy-2-naphthoic acid salts, more particularly a 1-hydroxy-2-naphthoic acid salt of 3-[2-(4-aminophenyl)ethyl]-8-benzyl-7-{2-[ethyl-(2-hydroxyethyl)amino]ethyl}-1-propyl-3,7-dihydropurine-2,6-dione (i.e., an L-97-1 xinafoic acid salt). Hydrates of the A1 adenosine receptor antagonist salts described herein are further provided. The invention further encompasses pharmaceutical compositions comprising a pharmaceutically acceptable salt of an A1 adenosine receptor antagonist in a pharmaceutically acceptable carrier. The compositions of the invention find use in methods for treating and preventing respiratory disorders.

    Abstract translation: 提供了治疗和预防呼吸系统疾病的方法和组合物。 本发明的方法包括向受试者施用治疗有效量的A 1 N 2腺苷受体拮抗剂的药学上可接受的盐，特别是1-羟基-2-萘甲酸盐或3-羟基-2 - 萘甲酸盐，更特别是3- [2-（4-氨基苯基）乙基] -8-苄基-7- {2- [乙基 - （2-羟乙基）氨基]乙酸的1-羟基-2-萘甲酸盐， 乙基} -1-丙基-3,7-二氢嘌呤-2,6-二酮（即L-97-1十一酸盐）。 进一步提供本文所述的A 1 N 2腺苷受体拮抗剂盐的水合物。 本发明还包括在药学上可接受的载体中包含A 1 N 2腺苷受体拮抗剂的药学上可接受的盐的药物组合物。 本发明的组合物可用于治疗和预防呼吸系统疾病的方法。

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