公开(公告)号：US11076667B2

公开(公告)日：2021-08-03

申请号：US16840096

申请日：2020-04-03

Applicant: Michael Joseph McCarthy

Inventor： Michael Joseph McCarthy

IPC: A45C13/02 ,  A45C13/10 ,  A45C11/00 ,  A45F3/04

Abstract: A backpack with magnetic back-panel is provided and configured to enable a user to store their valuable and fragile belongings in the backpack and use the magnetic back-panel to securely store the backpack against any metal structure. Through the easily accessible magnetic back panel, the backpack securely connects to most of, if not all, metal surfaces. With this magnetic feature, the backpack can be positioned vertically or horizontally on metal structures to give the user a plethora of options to position at their desired setting. These options provide an environment that reduces the chance of damage and theft to the backpack, while making completely accessible to the user and removing health and injury concerns.

公开(公告)号：US07765385B2

公开(公告)日：2010-07-27

申请号：US11736923

申请日：2007-04-18

Applicant: David L. Darrington ,  Patrick Joseph McCarthy ,  Amanda Peters ,  Albert Sidelnik

Inventor： David L. Darrington ,  Patrick Joseph McCarthy ,  Amanda Peters ,  Albert Sidelnik

IPC: G06F9/00

CPC classification number: G06F11/2007

Abstract: An apparatus and method for overcoming a torus network failure in a parallel computer system. A mesh routing mechanism in the service node of the computer system configures the nodes from a torus to a mesh network when a failure occurs in the torus network. The mesh routing mechanism takes advantage of cutoff registers in each node to route node to node data transfers around the faulty node or network connection.

Abstract translation: 一种在并行计算机系统中克服环面网络故障的装置和方法。 在环网中发生故障时，计算机系统的服务节点中的网状路由机制将环网配置为网状网络。 网格路由机制利用每个节点中的截止寄存器将节点路由到故障节点或网络连接周围的节点数据传输。

公开(公告)号：US07674822B2

公开(公告)日：2010-03-09

申请号：US11285223

申请日：2005-11-22

Applicant: Jinbo Lee ,  Michael J. Smith ,  Alessandro Fabio Moretto ,  Zhao-Kui Wan ,  Eva Deanna Binnun ,  Weixin Xu ,  Kenneth W. Foreman ,  Diane M. Joseph-McCarthy ,  David V. Erbe ,  Steve Y. Tam

Inventor： Jinbo Lee ,  Michael J. Smith ,  Alessandro Fabio Moretto ,  Zhao-Kui Wan ,  Eva Deanna Binnun ,  Weixin Xu ,  Kenneth W. Foreman ,  Diane M. Joseph-McCarthy ,  David V. Erbe ,  Steve Y. Tam

IPC: A61K31/381 ,  C07D495/04

CPC classification number: C07D495/04 ,  C07D333/70 ,  C07D333/74

Abstract: This invention relates to modulating (e.g., inhibiting) protein tyrosine phosphatase 1B (PTP1B).

Abstract translation: 本发明涉及调节（例如抑制）蛋白质酪氨酸磷酸酶1B（PTP1B）。

公开(公告)号：US07644254B2

公开(公告)日：2010-01-05

申请号：US11736811

申请日：2007-04-18

Applicant: David L. Darrington ,  Patrick Joseph McCarthy ,  Amanda Peters ,  Albert Sidelnik ,  Brian Edward Smith ,  Brent Allen Swartz

Inventor： David L. Darrington ,  Patrick Joseph McCarthy ,  Amanda Peters ,  Albert Sidelnik ,  Brian Edward Smith ,  Brent Allen Swartz

IPC: G06F15/173

CPC classification number: H04L45/22 ,  G06F11/203 ,  G06F11/2038 ,  G06F11/2051 ,  G06F15/17381 ,  H04L41/0659 ,  H04L45/00 ,  H04L45/02 ,  H04L45/28

Abstract: A method and apparatus for dynamically rerouting node processes on the compute nodes of a massively parallel computer system using hint bits to route around failed nodes or congested networks without restarting applications executing on the system. When a node has a failure or there are indications that it may fail, the application software on the system is suspended while the data on the failed node is moved to a backup node. The torus network traffic is routed around the failed node and traffic for the failed node is rerouted to the backup node. The application can then resume operation without restarting from the beginning.

Abstract translation: 一种方法和装置，用于在大型并行计算机系统的计算节点上动态重新路由节点进程，该提取位使用提示位来绕故障节点或拥塞​​网络路由，而不重新启动在系统上执行的应用。 当节点发生故障或有迹象表明可能会失败时，系统上的应用软件将被暂停，同时将故障节点上的数据移动到备份节点。 环网网络流量围绕故障节点进行路由，故障节点的流量将重新路由到备份节点。 然后，应用程序可以从头开始重新启动。

公开(公告)号：US07512836B2

公开(公告)日：2009-03-31

申请号：US11608891

申请日：2006-12-11

Applicant: David L. Darrington ,  Patrick Joseph McCarthy ,  Amanda Peters ,  Albert Sidelnik

Inventor： David L. Darrington ,  Patrick Joseph McCarthy ,  Amanda Peters ,  Albert Sidelnik

IPC: G06F11/20

CPC classification number: G06F11/203 ,  G06F11/2025 ,  G06F11/2041

Abstract: A method and apparatus for fast backup of a set of compute nodes to save the state of the software in a parallel computer system. A fast backup mechanism in the service node of the computer system configures a set of nodes to be used for a backup and when needed uses the network hardware to perform a fast backup from node to node from an original set of nodes to the backup set of nodes. In the preferred embodiments a the fast backup is done with respect to a midplane or rack of nodes copied to a backup rack of nodes.

Abstract translation: 一种用于快速备份一组计算节点以便在并行计算机系统中保存软件的状态的方法和装置。 计算机系统的服务节点中的快速备份机制配置要用于备份的一组节点，并且当需要时使用网络硬件来执行从节点到节点从原始节点组到备份组的快速备份 节点。 在优选实施例中，快速备份相对于复制到节点的备份机架的中间面或机架节点进行。

公开(公告)号：US20090048286A1

公开(公告)日：2009-02-19

申请号：US12236121

申请日：2008-09-23

Applicant: Jinbo Lee ,  Steven J. Kirincich ,  Michael J. Smith ,  Douglas P. Wilson ,  Bruce C. Follows ,  Zhao-Kui Wan ,  Diane M. Joseph-McCarthy ,  David V. Erbe ,  Yan-Ling Zhang ,  Weixin Xu ,  Steve Y. Tam

Inventor： Jinbo Lee ,  Steven J. Kirincich ,  Michael J. Smith ,  Douglas P. Wilson ,  Bruce C. Follows ,  Zhao-Kui Wan ,  Diane M. Joseph-McCarthy ,  David V. Erbe ,  Yan-Ling Zhang ,  Weixin Xu ,  Steve Y. Tam

IPC: A61K31/4365 ,  C07D495/04 ,  A61K31/381 ,  C07D333/70 ,  C12N9/99

CPC classification number: C07D495/04 ,  C07D333/70

Abstract: Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted bicyclic fused-thiophene compounds can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.

Abstract translation: 蛋白酪氨酸磷酸酶（PTPases）如PTP1B可以在调节各种细胞反应（如胰岛素信号）中发挥作用。 取代的双环稠合噻吩化合物可以抑制PTP1B，从而诱导更大的胰岛素敏感性。 因此，PTP1B抑制可以为PTPase介导的病症例如糖尿病提供替代治疗。

公开(公告)号：US20080263387A1

公开(公告)日：2008-10-23

申请号：US11736923

申请日：2007-04-18

Applicant: David L. Darrington ,  Patrick Joseph McCarthy ,  Amanda Peters ,  Albert Sidelnik

Inventor： David L. Darrington ,  Patrick Joseph McCarthy ,  Amanda Peters ,  Albert Sidelnik

IPC: G06F11/00

CPC classification number: G06F11/2007

Abstract: An apparatus and method for overcoming a torus network failure in a parallel computer system. A mesh routing mechanism in the service node of the computer system configures the nodes from a torus to a mesh network when a failure occurs in the torus network. The mesh routing mechanism takes advantage of cutoff registers in each node to route node to node data transfers around the faulty node or network connection.

Abstract translation: 一种在并行计算机系统中克服环面网络故障的装置和方法。 在环网中发生故障时，计算机系统的服务节点中的网状路由机制将环网配置为网状网络。 网格路由机制利用每个节点中的截止寄存器将节点路由到故障节点或网络连接周围的节点数据传输。

公开(公告)号：US20060140346A1

公开(公告)日：2006-06-29

申请号：US11302466

申请日：2005-12-13

Applicant: Joseph McCarthy

Inventor： Joseph McCarthy

IPC: H01J35/12 ,  H01J35/10

CPC classification number: H05G1/02 ,  F25B1/06 ,  F25B23/00 ,  F25B2341/0011 ,  F25B2500/01 ,  H01J2235/127 ,  H01J2235/1275 ,  H05G1/025

Abstract: A system and method for reducing or eliminating pump cavitation in a closed system having at least one or a plurality of fluid phase changes. The system comprises a venturi having a throat which is coupled to a reservoir tank.

公开(公告)号：US20050271347A1

公开(公告)日：2005-12-08

申请号：US11056870

申请日：2005-02-11

Applicant: Ronald Kimball ,  Robert Knowlton ,  Joseph McCarthy ,  Ji Wang ,  Donnell Walton ,  Luis Zenteno

Inventor： Ronald Kimball ,  Robert Knowlton ,  Joseph McCarthy ,  Ji Wang ,  Donnell Walton ,  Luis Zenteno

IPC: C03B37/014 ,  C03B37/023 ,  C03C13/04 ,  G02B6/00 ,  G02B6/024 ,  G02B6/036 ,  H01S3/067 ,  H01S3/16

CPC classification number: C03B37/01413 ,  C03B2201/10 ,  C03B2201/12 ,  C03B2201/14 ,  C03B2201/28 ,  C03B2201/31 ,  C03B2201/32 ,  C03B2201/34 ,  C03B2201/36 ,  C03B2203/04 ,  C03B2203/10 ,  C03B2203/23 ,  C03B2203/30 ,  C03B2207/85 ,  C03B2207/90 ,  C03C13/046 ,  G02B6/024 ,  G02B6/03611 ,  G02B6/0365 ,  G02B6/03694 ,  H01S3/06716 ,  H01S3/1618

Abstract: According to one example of the invention an optical fiber comprises: (i) silica based, rare earth doped core having a first index of refraction n1; (ii) at least one silica based cladding surrounding the core and having a second index of refraction n2, such that n1>n2; wherein at least one of the core or cladding is doped with Al2O3, such that the ratio of max wt % to min wt % of Al2O3 concentration is less than 2:1

Abstract translation: 根据本发明的一个示例，光纤包括：（i）具有第一折射率n 1的二氧化硅基稀土掺杂的核; （ii）至少一个二氧化硅基包层，其围绕所述芯并具有第二折射率n 2 2，使得n 1/2 2 n 2 ; 其中所述芯或包层中的至少一个掺杂有Al 2 O 3 3，使得Al 2 O 3的最大重量％与最小重量％的比例< / 3 3 3浓度小于2:1

公开(公告)号：US06972020B1

公开(公告)日：2005-12-06

申请号：US10159269

申请日：2002-06-03

Applicant: Barry Grayson ,  Bruno Vendittelli ,  Joseph McCarthy ,  Matthew Harrow ,  Brian Schumacher

Inventor： Barry Grayson ,  Bruno Vendittelli ,  Joseph McCarthy ,  Matthew Harrow ,  Brian Schumacher

IPC: A61B17/58 ,  A61B17/66

CPC classification number: A61B17/663

Abstract: The present invention provides an improved orthopedic system for the modification of the distance between the maxilla and zygoma. In a preferred embodiment, the system includes proximal and distal footplates attached to an orthopedic device. The distal footplate is attached to the zygoma, with the proximal footplate being mechanically coupled to the maxilla. This mechanical coupling is achieved either through attachment directly to the maxilla or by attachment to a construct which is then wired to the patient's teeth. The orthopedic device, which may be a distractor, allows for modification of the distance between the maxilla and zygoma. The entire system can advantageously be placed intra-orally within a patient. In a preferred embodiment, the footplates are also detachable from the orthopedic device and are composed of a bioresorbable material, such that they will be absorbed by the patient's body. Methods for using this novel orthopedic system are also disclosed.

Abstract translation: 本发明提供了一种改进的矫形系统，用于修改上颌骨和合子之间的距离。 在优选实施例中，系统包括附接到整形外科装置的近端和远端足板。 远端足底板连接到合子，近端足底板与上颌骨机械联接。 这种机械联接可以通过直接连接到上颌骨上或者通过附接到构造物来实现，然后将其结合到患者的牙齿上。 可能是牵引器的矫形装置允许修改上颌骨和合子之间的距离。 整个系统可有利地被口内放置在患者体内。 在一个优选实施例中，脚踏板也可从矫形装置拆卸，并且由生物可再吸收的材料组成，使得它们将被患者的身体吸收。 还公开了使用这种新型矫形系统的方法。